Case Reports in Rheumatology最新文献_第3页

Antisynthetase Syndrome in a Patient with Pulmonary Embolism and Nonbacterial Thrombotic Endocarditis. 肺栓塞合并非细菌性血栓性心内膜炎患者的抗合成酶综合征。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/9068597

Anusha Vege, Jesse Beery, Areeba Kara

引用次数: 2

Peripheral Spondyloarthritis Presenting with Fever and Severe Systemic Inflammatory Response Mimicking Infection: A Case Series and Literature Review. 周围性脊柱炎表现为发热和严重的全身炎症反应模拟感染:一个病例系列和文献回顾。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/6651961

Ibrahim Abdulmomen, Eman Satti, Basem Awadh

{"title":"Peripheral Spondyloarthritis Presenting with Fever and Severe Systemic Inflammatory Response Mimicking Infection: A Case Series and Literature Review.","authors":"Ibrahim Abdulmomen, Eman Satti, Basem Awadh","doi":"10.1155/2023/6651961","DOIUrl":"https://doi.org/10.1155/2023/6651961","url":null,"abstract":"Objective: To describe four peripheral spondyloarthritis patients presenting with fever and severe systemic inflammatory response mimicking infection.Methods: Between 2017 and 2019, four patients with the final diagnosis of peripheral spondyloarthritis had atypical presentation of fever and severe systemic inflammatory response requiring hospital admission and extensive workup.Results: We reported four patients who were admitted to the hospital for fever and arthritis. They all had laboratory tests of the severe systemic inflammatory response (leukocytosis, thrombocytosis, high ESR, and high CRP) concerning infection. They underwent extensive workup for infectious causes, including septic arthritis, which came back negative. Other rheumatic diseases that are known to present with fever such as adult-onset Still's disease, reactive arthritis, and crystal arthritis were all excluded. The final diagnosis of spondyloarthritis was made during their follow-up: three patients with peripheral spondyloarthritis and one with psoriatic arthritis. All patients received conventional DMARDs (methotrexate and sulfasalazine) and two patients received tumor necrosis factor inhibitors in addition to conventional DMARDs to control their disease.Conclusion: We observed a subgroup of peripheral spondyloarthritis patients presenting with fever and severe systemic inflammatory response requiring hospitalization. Recognition of this subgroup is important and should be considered once an infection is ruled out.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"6651961"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9887909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy. 他汀类药物治疗5年后出现的免疫介导的坏死性肌病。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/1178035

Nathan G DeRon, Francis Fischer, Dylan Lopez, Elizabeth C Brewer

{"title":"Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy.","authors":"Nathan G DeRon, Francis Fischer, Dylan Lopez, Elizabeth C Brewer","doi":"10.1155/2023/1178035","DOIUrl":"https://doi.org/10.1155/2023/1178035","url":null,"abstract":"Immune-mediated necrotizing myopathy (IMNM) is an increasingly common and serious condition in which autoantibodies attack muscle fibers causing clinically significant muscle weakness, fatigue, and myalgias. Recognizing the clinical presentation of IMNM is difficult but necessary, as rapid intervention decreases morbidity. We present a case of a 53-year-old female with IMNM induced by statin therapy with confirmed anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibodies present on serologic testing. The patient's statin therapy was halted, and the patient was provided with one dose of methylprednisolone and ongoing therapy with mycophenolate. She showed subsequent slow improvements in her muscle weakness and myalgias. It is important for clinicians to be aware of the possible consequences of statin therapy, as these drugs are generally regarded as benign in the medical community. Clinicians should also be aware that statin-induced myopathy can occur at any time during statin therapy. The condition does not necessarily correlate with beginning a new statin medication, as demonstrated in this case in which the patient was on chronic statin therapy before developing symptoms. Continued clinician education and building the fund of medical knowledge regarding this disease are vital to enable clinicians to recognize this disease and act promptly to reduce patient morbidity and improve outcomes.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"1178035"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9410852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Previously Undiagnosed Systemic Lupus Erythematosus and Mycobacterium tuberculosis Infection Presenting as Diffuse Alveolar Hemorrhage. 以弥漫性肺泡出血为表现的系统性红斑狼疮合并结核分枝杆菌感染1例。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/3686772

Henna Iqbal, Benny Screws, Muhammad S Khan

引用次数: 1

Childhood-Onset COPA Syndrome Recognized Retrospectively in the Context of Polyarticular Juvenile Idiopathic Arthritis and Rheumatoid Arthritis. 儿童期发作的COPA综合征在多关节幼年特发性关节炎和类风湿关节炎的背景下回顾性识别。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/3240245

Roko P A Nikolic, Cristina Moran Toro

引用次数: 0

Systemic Mastocytosis: A Mimicker of Reactive Arthritis. 系统性肥大细胞增多症:反应性关节炎的模拟者。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/6655005

Oussama G Nasrallah, Razan Mohty, Jean El-Cheikh, Mira Merashli

引用次数: 0

Use of Doxycycline in a Patient following Minocycline-Induced Lupus. 多西环素在二甲胺四环素诱发狼疮患者中的应用。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/7353644

Katherine Quinn Newman, Charles Guy Castles

引用次数: 0

A 20-Year-Old Man with IgA Vasculitis following COVID-19 Vaccination. 1例20岁男性在接种COVID-19疫苗后出现IgA血管炎。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/9505383

Abdulaziz Alsubaie, Abdulmajeed Alshabanat, Abdulrahman Almizel, Mohammed Omair, Rahaf Alodaini

引用次数: 0

A Rare Case of Takayasu Arteritis Presenting as Pericarditis with Effusion. 罕见的高须动脉炎表现为心包炎并积液。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/6044765

Ian J Robertson, David K Mecham, Lisa M Conte, Michael F Loncharich

{"title":"A Rare Case of Takayasu Arteritis Presenting as Pericarditis with Effusion.","authors":"Ian J Robertson, David K Mecham, Lisa M Conte, Michael F Loncharich","doi":"10.1155/2023/6044765","DOIUrl":"https://doi.org/10.1155/2023/6044765","url":null,"abstract":"Takayasu arteritis (TAK) is a rare large-vessel vasculitis that is seen primarily in young females of Asian descent and is infrequently diagnosed in the United States. Pericardial effusion with or without pericarditis as a presenting feature of TAK is rare, with only about five percent of cases of pericarditis attributable to any autoimmune etiology. We present a case of a 22-year-old Caucasian woman who presented with a large, symptomatic pericardial effusion of unclear etiology, who after extensive laboratory workup and imaging to include whole-body positron emission tomography (PET) was diagnosed with TAK. In our patient, the use of whole-body PET showing characteristic hypermetabolism within the aortic arch helped secure our diagnosis while avoiding the need for pericardiocentesis. The patient had rapid symptomatic and radiographic improvement with the use of high-dose oral steroids in addition to colchicine and ibuprofen for her pericarditis and associated pericardial effusion. At follow-up just 1 week after initiation of steroids, only trace effusion was identified on transthoracic echocardiogram.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"6044765"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10151307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of an Elderly Woman Who Developed Corneal Perforation in the Clinical Course of Myeloperoxidase Positive Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. 老年妇女髓过氧化物酶阳性抗中性粒细胞细胞质抗体相关血管炎临床过程中出现角膜穿孔1例。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/4246075

Shuhei Kobayashi, Makoto Harada, Aiko Yamada, Yasuhiro Iesato, Koji Hashimoto, Yuji Kamijo

{"title":"A Case of an Elderly Woman Who Developed Corneal Perforation in the Clinical Course of Myeloperoxidase Positive Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.","authors":"Shuhei Kobayashi, Makoto Harada, Aiko Yamada, Yasuhiro Iesato, Koji Hashimoto, Yuji Kamijo","doi":"10.1155/2023/4246075","DOIUrl":"https://doi.org/10.1155/2023/4246075","url":null,"abstract":"Antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV) is a systemic vasculitis characterized by ANCA positivity and categorized into three main types: microscopic polyangiitis, granulomatosis with polyangiitis, and eosinophilic granulomatous with polyangiitis. Although AAV leads to systemic organ injury, such as of the lungs, kidneys, nerves, and skin, patients with AAV sometimes develop ocular lesions. Here, we report the case of an elderly woman who had been treated for AAV for seven years. She developed scleritis and relapsed twice, with elevation of serum disease markers such as ANCA titer and C-reactive protein. After the decline of these markers due to treatment with additional medication, her scleritis relapsed again and caused a corneal ulcer, which resulted in perforation without obvious marker elevation. She did not present with any symptoms of organ injury, except for ocular lesions. She was treated with surgery, followed by methylprednisolone and rituximab therapy. Subsequently, her ocular lesions and symptoms improved, and she did not relapse. AAV can cause various ocular manifestations. Although C-reactive protein and ANCA titers are useful markers of disease activity and the relapse of AAV complications, including ocular lesions, these markers do not always increase at the time of worsening ocular lesions. Therefore, it is important for clinicians treating patients with AAV to pay careful attention to serum data and physical findings, including the eyes.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"4246075"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10151310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0