Kevin R Murray, Diana Cagliero, Thomas Kiebalo, Sarah Engelhart
{"title":"Scorbut chez une femme de 65 ans dont la capacité fonctionnelle et le réseau social sont fort limités.","authors":"Kevin R Murray, Diana Cagliero, Thomas Kiebalo, Sarah Engelhart","doi":"10.1503/cmaj.240769-f","DOIUrl":"10.1503/cmaj.240769-f","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 41","pages":"E1377-E1379"},"PeriodicalIF":9.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Empyema necessitans: a rare presentation of <i>Mycobacterium tuberculosis</i> infection.","authors":"Jenny Lu-Song, Monique Raubenheimer, Vivek Dhawan","doi":"10.1503/cmaj.240694","DOIUrl":"10.1503/cmaj.240694","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 41","pages":"E1370-E1373"},"PeriodicalIF":9.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Celina DeBiasio, Elizabeth Nizalik, Genevieve Gavigan
{"title":"Linear morphea: a persistent bruise on the temple of a 9-year-old boy.","authors":"Celina DeBiasio, Elizabeth Nizalik, Genevieve Gavigan","doi":"10.1503/cmaj.241089","DOIUrl":"10.1503/cmaj.241089","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 41","pages":"E1375-E1376"},"PeriodicalIF":9.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcella Cabral Caires, Keren Mbondo Kasuku, Bethlehem Mengesha, Habibat Garuba, Angeline Law, Christopher Johnson, David Ian Paterson, Carole Dennie, Elena Pena, Li Chen, Benjamin J W Chow, Gary R Small
{"title":"Prognostic importance of extensive coronary calcium on lung cancer screening chest computed tomography.","authors":"Marcella Cabral Caires, Keren Mbondo Kasuku, Bethlehem Mengesha, Habibat Garuba, Angeline Law, Christopher Johnson, David Ian Paterson, Carole Dennie, Elena Pena, Li Chen, Benjamin J W Chow, Gary R Small","doi":"10.1503/cmaj.231602","DOIUrl":"10.1503/cmaj.231602","url":null,"abstract":"<p><strong>Background: </strong>Low-dose chest computed tomography (CT) is used for lung cancer screening, but can also detect coronary artery disease as coronary artery calcium. We sought to determine the prevalence and prognostic utility of coronary artery calcium in a population at high risk of cancer.</p><p><strong>Methods: </strong>We reviewed CT scans from consecutive participants screened for lung cancer between March 2017 and November 2018 as part of the Ontario Health Lung Cancer Screening Pilot for People at High Risk. We quantified coronary artery calcium using an estimated Agatston score. We identified the composite primary outcome of all-cause death and cardiovascular events using linked electronic medical record data from The Ottawa Hospital to December 2023.</p><p><strong>Results: </strong>Among 1486 people who underwent screening CT, coronary artery calcium was detected in 1232 (82.9%) and was extensive in 439 (29.5%). On multivariable analysis, extensive coronary artery calcium was associated with the composite primary outcome (hazard ratio [HR] 2.13, 95% confidence interval [CI] 1.35-3.38), all-cause death (HR 2.39, 95% CI 1.34-4.27), and cardiovascular events (HR 2.06, 95% CI 1.13-3.77). Extensive coronary artery calcium remained predictive of cardiovascular events after we adjusted for noncardiovascular death as a competing risk (HR 2.05, 95% CI 1.09-3.85).</p><p><strong>Interpretation: </strong>Among people undergoing low-dose chest CT for lung cancer screening, extensive coronary artery calcium was an independent predictor of all-cause death and cardiovascular events, even after adjustment for noncardiovascular death. The opportunity to identify and reduce risks from coronary artery disease may represent an additional benefit of lung cancer screening.</p>","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 41","pages":"E1362-E1369"},"PeriodicalIF":9.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nevena Rebić, Lucy Cheng, Michael R Law, Jacquelyn J Cragg, Lori A Brotto, Mary A De Vera
{"title":"Predictors of cost-related medication nonadherence in Canada: a repeated cross-sectional analysis of the Canadian Community Health Survey.","authors":"Nevena Rebić, Lucy Cheng, Michael R Law, Jacquelyn J Cragg, Lori A Brotto, Mary A De Vera","doi":"10.1503/cmaj.241024","DOIUrl":"10.1503/cmaj.241024","url":null,"abstract":"<p><strong>Background: </strong>In Canada, many patients face substantial out-of-pocket costs for prescription medication, which may affect their ability to take their medications as prescribed. We sought to conduct a comprehensive analysis of the burden and predictors of cost-related nonadherence in Canada.</p><p><strong>Methods: </strong>Using pooled data from the 2015, 2016, 2018, 2019, and 2020 iterations of the Canadian Community Health Survey, we calculated weighted population estimates of the burden of cost-related nonadherence in the preceding 12 months and used logistic regression models to measure the association of 15 demographic, health, and health system predictors of cost-related nonadherence overall and stratified by sex.</p><p><strong>Results: </strong>We included 223 085 respondents. We found that 4.9% of respondents aged 12 years or older reported cost-related nonadherence. Those who self-identified as female, belonging to a racial or ethnic minority group, or bisexual, pansexual, or questioning were more likely to report cost-related nonadherence. Younger age, higher disease burden, poorer health, non-employer prescription drug coverage, and not living in the province of Quebec were associated with cost-related nonadherence.</p><p><strong>Interpretation: </strong>Our nationally representative findings reveal inequities that disproportionally affect marginalized people at the intersections of sex, race, age, and disability, and vary by province. This foundational understanding of the state of cost-related nonadherence may be used to inform potential expansion of public drug coverage eligibility, premiums, and cost-sharing policies that address financial barriers to medication adherence.</p>","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 40","pages":"E1331-E1340"},"PeriodicalIF":9.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccination contre le virus respiratoire syncytial pendant la grossesse.","authors":"Bahaa Abu-Raya, Joanne M Langley, Pascal Lavoie","doi":"10.1503/cmaj.240773-f","DOIUrl":"10.1503/cmaj.240773-f","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 40","pages":"E1353-E1354"},"PeriodicalIF":9.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The first, fragile foundations of national pharmacare in Canada.","authors":"Matthew B Stanbrook","doi":"10.1503/cmaj.241650","DOIUrl":"10.1503/cmaj.241650","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 40","pages":"E1347-E1348"},"PeriodicalIF":9.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Des mesures pour éviter les blessures liées aux voiturettes de golf sont requises de toute urgence.","authors":"Douglas Lau, Tara Esbati, Michael D Cusimano","doi":"10.1503/cmaj.240583-f","DOIUrl":"10.1503/cmaj.240583-f","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 40","pages":"E1359-E1361"},"PeriodicalIF":9.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"People who use wheelchairs.","authors":"Lisa Freeman","doi":"10.1503/cmaj.241433","DOIUrl":"10.1503/cmaj.241433","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 40","pages":"E1346"},"PeriodicalIF":9.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nirsévimab pour réduire la morbidité infantile causée par le virus respiratoire syncytial.","authors":"Bahaa Abu-Raya, Joanne M Langley, Pascal Lavoie","doi":"10.1503/cmaj.240780-f","DOIUrl":"10.1503/cmaj.240780-f","url":null,"abstract":"","PeriodicalId":9609,"journal":{"name":"Canadian Medical Association journal","volume":"196 40","pages":"E1349-E1352"},"PeriodicalIF":9.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}