Case Reports in Nephrology最新文献_第9页

Renal Tubular Acidosis in the Postpartum Period: A Case Report and Literature Review. 产后肾小管酸中毒1例报告及文献复习。

Case Reports in Nephrology Pub Date : 2021-09-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6693013

Carlos E Duran, Mayra Estacio, Fredy Lozano, Esteban Echeverri, Maria Juliana Riascos, Juan Guillermo Posada, Johanna Schweineberg

引用次数: 1

COVID-19 and APOL-1 High-Risk Genotype-Associated Collapsing Glomerulonephritis. COVID-19和apol1高危基因型相关塌陷性肾小球肾炎

Case Reports in Nephrology Pub Date : 2021-08-04 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3737751

Sasmit Roy, Srikanth Kunaparaju, Narayana Murty Koduri, Vikram Sangani, Mytri Pokal, Venu Madhav Konala, Mamtha Balla, Sreedhar Adapa

引用次数: 6

Acute Kidney Injury Secondary to Rhabdomyolysis and COVID-19: A Case Report and Literature Review. 横纹肌溶解和 COVID-19 引起的急性肾损伤：病例报告和文献综述

Case Reports in Nephrology Pub Date : 2021-08-02 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5528461

Vishaka K Chetram, Akram I Ahmad, Saira Farid, Tanuj Sood

引用次数: 0

A 24-Year-Old Female Transplant Recipient with Type 2 Membranoproliferative Glomerulonephritis and Disseminated Shingles: A Cautionary Tale of Deferring to Primary Care. 24岁女性2型膜增生性肾小球肾炎和播散性带状疱疹移植受体:推迟初级保健的警示故事。

Case Reports in Nephrology Pub Date : 2021-07-24 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6663689

Benjamin T Burdorf

{"title":"A 24-Year-Old Female Transplant Recipient with Type 2 Membranoproliferative Glomerulonephritis and Disseminated Shingles: A Cautionary Tale of Deferring to Primary Care.","authors":"Benjamin T Burdorf","doi":"10.1155/2021/6663689","DOIUrl":"https://doi.org/10.1155/2021/6663689","url":null,"abstract":"In this report, the case of a 24-year-old Caucasian female with type 2 membranoproliferative glomerulonephritis status-post living donor kidney transplant managed on triple regimen immunosuppressive therapy who developed shingles is discussed. With its onset, she promptly reached out to her nephrologist who deferred her to primary care. Prior to seeing her primary provider, she developed disseminated herpes zoster. She consulted emergency services where she was given inadequate care and again deferred to primary care. One day later, the dissemination included her entire torso, face, oral cavity, and all extremities. Fortunately, the patient had the insight to again reach out to her nephrologist who arranged for her to be admitted for appropriate care 6 days after her initial inquiry that carried 6 days of zoster progression. This case demonstrates how it is pertinent that specialists recognize potentially lethal complications associated with the conditions they follow. Although convenient to defer to primary care, if specialists were to take on the responsibility of providing a broader scope of care for their unique subsets of patients, it would likely result in a reduction in the 80% of serious medical errors that occur as a result of miscommunication, or lack thereof, between care providers.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":"2021 ","pages":"6663689"},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39269469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical Antiglomerular Basement Membrane Disease in a Pediatric Patient Successfully Treated with Rituximab. 非典型抗肾小球基底膜病的儿童患者成功治疗利妥昔单抗。

Case Reports in Nephrology Pub Date : 2021-07-17 eCollection Date: 2021-01-01 DOI: 10.1155/2021/2586693

Kuang-Yu Jen, Ari Auron

{"title":"Atypical Antiglomerular Basement Membrane Disease in a Pediatric Patient Successfully Treated with Rituximab.","authors":"Kuang-Yu Jen, Ari Auron","doi":"10.1155/2021/2586693","DOIUrl":"https://doi.org/10.1155/2021/2586693","url":null,"abstract":"Classic antiglomerular basement membrane (anti-GBM) disease is an exceedingly rare but extremely aggressive form of glomerulonephritis, typically caused by autoantibodies directed against cryptic, conformational epitopes within the noncollagenous domain of the type IV collagen alpha-3 subunit. Pathologic diagnosis is established by the presence of strong, diffuse, linear staining for immunoglobulin on immunofluorescence microscopy. Recently, patients with atypical clinical and pathologic findings of anti-GBM disease have been described. These patients tend to have an indolent clinical course, without pulmonary involvement, and laboratory testing rarely reveals the presence of anti-GBM antibodies. Specific guidelines for the treatment and management of these patients are unclear. Here, we describe a case of atypical anti-GBM disease in a young child who presented with hematuria and prominent proteinuria. Throughout the course of his illness, creatinine remained normal. He was conservatively treated with steroids and rituximab, resulting in resolution of his clinical symptoms and normalization of laboratory findings.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":"2021 ","pages":"2586693"},"PeriodicalIF":0.0,"publicationDate":"2021-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39265849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Complex Case of Emphysematous Cystitis in a Peritoneal Dialysis Patient. 腹膜透析患者并发复杂肺气肿性膀胱炎1例。

Case Reports in Nephrology Pub Date : 2021-07-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8343022

Christina Okello, Rajesh Raj

引用次数: 0

Bartonella-Associated Endocarditis with Severe Active Crescentic Glomerulonephritis and Acute Renal Failure. 巴尔通体相关心内膜炎合并严重活动性月牙状肾小球肾炎和急性肾功能衰竭。

Case Reports in Nephrology Pub Date : 2021-05-29 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9951264

Ramanath Dukkipati, Benjamin Lawson, Cynthia C Nast, Anuja Shah

引用次数: 3

Profound Metabolic Acidosis due to Metformin Intoxication Requiring Dialysis. 二甲双胍中毒引起的需要透析的深度代谢性酸中毒。

Case Reports in Nephrology Pub Date : 2021-05-24 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9914982

Klodia Hermez, Carla Dudash-Mion

{"title":"Profound Metabolic Acidosis due to Metformin Intoxication Requiring Dialysis.","authors":"Klodia Hermez, Carla Dudash-Mion","doi":"10.1155/2021/9914982","DOIUrl":"https://doi.org/10.1155/2021/9914982","url":null,"abstract":"Metformin-associated lactic acidosis (MALA) is a rare but life-threatening condition with often high mortality rates. Despite this, metformin continues to be one of the most commonly prescribed antihyperglycemic agents in the market. We present a unique case of a 61-year-old female with severe acidosis of pH = 6.72 and lactic acid of 26 mmol/L who presented obtunded after ingestion of an unknown amount of metformin. She was subsequently intubated, became hypotensive, and was initiated on vasopressors. She was swiftly started on a combination of intermittent hemodialysis (IHD) and bicarbonate therapy 7 hours after admission followed by continuous renal replacement therapy (CRRT) as she became more hemodynamically unstable. The patient's renal function improved, and she was discharged 7 days after admission with favorable sequelae. Dialysis is often reported in cases of severe MALA; however, it remains unclear how quickly dialysis should be initiated. This case aims to explore the benefits of quick initiation of extracorporeal measures in the forms of IHD and CRRT with concurrent bicarbonate supplementation. Furthermore, this case demonstrates the importance of clinical suspicion in metabolic acidosis in a patient on metformin therapy.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":"2021 ","pages":"9914982"},"PeriodicalIF":0.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39090603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A Case of Severe and Refractory Membranous Nephropathy Associated to Mucous Membrane Pemphigoid. 严重难治性膜性肾病伴黏膜类天疱疮1例。

Case Reports in Nephrology Pub Date : 2021-05-11 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9940293

Eric Mereniuk, Laura Sabbah, Jean-Paul Makhzoum

{"title":"A Case of Severe and Refractory Membranous Nephropathy Associated to Mucous Membrane Pemphigoid.","authors":"Eric Mereniuk, Laura Sabbah, Jean-Paul Makhzoum","doi":"10.1155/2021/9940293","DOIUrl":"https://doi.org/10.1155/2021/9940293","url":null,"abstract":"Primary membranous nephropathy (MN) and mucous membrane pemphigoid (MMP) are two autoimmune conditions with well-defined diagnostic and treatment guidelines. MN has been linked to bullous pemphigoid (BP) in certain case reports, though little is known regarding the association of MN and other bullous diseases. The association of MN and MMP has rarely been described, and very little data exist regarding the treatment of this association. We report a case of severe refractory membranous nephropathy secondary to mucous membrane pemphigoid successfully treated with rituximab. A 35-year-old woman with known MMP was referred to our clinic for new-onset generalized edema and proteinuria. MN was confirmed on renal biopsy. Despite therapy with high-dose systemic glucocorticoids, combined with mycophenolate mofetil, and later azathioprine, nephrotic-range proteinuria persisted even at a daily dose of prednisone of 40 mg. The patient was then started on rituximab infusions, which induced remission of both mucous membrane pemphigoid and membranous glomerulonephritis. This suggests that MN can be secondary to MMP, and rituximab may be useful induce remission in cases that are refractory to standard therapy.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":"2021 ","pages":"9940293"},"PeriodicalIF":0.0,"publicationDate":"2021-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39034644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A Rare Case of Immunotactoid Glomerulopathy Associated with Hodgkin Lymphoma. 免疫因子样肾小球病变合并霍奇金淋巴瘤1例。

Case Reports in Nephrology Pub Date : 2021-05-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5527966

Keiki Nagaharu, Yuka Sugimoto, Keiki Kawakami

{"title":"A Rare Case of Immunotactoid Glomerulopathy Associated with Hodgkin Lymphoma.","authors":"Keiki Nagaharu, Yuka Sugimoto, Keiki Kawakami","doi":"10.1155/2021/5527966","DOIUrl":"https://doi.org/10.1155/2021/5527966","url":null,"abstract":"Immunotactoid glomerulopathy (ITG) is characterized by Congo red-negative microtubular deposits, and it has been reported as a rare paraneoplastic syndrome due to hematologic malignancies, viral infections, or autoimmune diseases. In hematologic malignancies, multiple myeloma and other mature B-cell malignancies are the most common hematologic malignancies, and Hodgkin lymphoma (HL) is extremely rare. A 59-year-old woman was admitted to our hospital because of a pulmonary mass and proteinuria. Computed tomography-guided lung biopsy confirmed the presence of HL stage IIA. Immunofixation of peripheral blood was positive for immunoglobulin G (IgG) kappa. Renal biopsy showed mesangial proliferation with deposits in the subendothelial lesion and no invasion of the HL. These deposits were positive for IgG3, C3, and kappa light chain but negative for C1q and lambda light chain. Electron microscopy showed randomly aligned tubular structures with a diameter of approximately 50 nm. We diagnosed the patient with immunotactoid nephropathy and HL. After systemic chemotherapy, the patient achieved a complete response and loss of proteinuria. On the contrary, her serum monoclonal gammopathy was observed after chemotherapy. The existence of a monoclonal antibody itself might not be a sufficient factor for ITG in some cases, and an additive trigger is necessary for development.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":"2021 ","pages":"5527966"},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38940904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1