New Journal of Chemistry最新文献

{"title":"K, Rb-hydroxyborates series with deep-ultraviolet KRbB5O8(OH) possessing moderate second harmonic generation response†","authors":"Aihaimaitijiang Ababaikeri, Xueting Pan, Xueling Hou and Jian Han","doi":"10.1039/D4NJ04016C","DOIUrl":"https://doi.org/10.1039/D4NJ04016C","url":null,"abstract":"<p >Herein, we reported three new hydroxyborate crystals, KRbB<small>₅</small>O<small>₈</small>(OH) (<strong>I</strong>), KRbB<small>₆</small>O<small>₉</small>(OH)<small>₂</small> (<strong>II</strong>), and K<small>_3.3</small>Rb<small>_0.7</small>B<small>₁₀</small>O<small>₁₅</small>(OH)<small>₄</small> (<strong>III</strong>), synthesized <em>via</em> a high-temperature solution method and hydrothermal method. Among them, <strong>I</strong> features a short deep-UV cut-off edge (190 nm), a moderate phase-matching second harmonic generation (SHG) response (0.9 × KDP), and an experimental birefringence of 0.025@546.1 nm. Besides, the syntheses, crystal structures, refractive indexes, and thermal properties of <strong>I</strong>, <strong>II</strong>, and <strong>III</strong> were investigated. In addition, the first-principles calculation was conducted to comprehend the relationship between the microstructure and macro optical property of <strong>I</strong>.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 46","pages":" 19501-19507"},"PeriodicalIF":2.7,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondria targeting combined with methyl modification of novel resveratrol derivatives enhances anti-tumor activity†","authors":"Jiang-Nan Wang, Mei-Nuo Chen, Chang Gao, Yi-Zhuo Yue, Zi-Yan Wang, Xiao-Lei Zhang, Yan-Fei Kang and Zhen-Hui Xin","doi":"10.1039/D4NJ04125A","DOIUrl":"https://doi.org/10.1039/D4NJ04125A","url":null,"abstract":"<p >Mitochondria-targeting methyl modification compounds <strong>A1–A6</strong> were synthesized by introducing TPP<small>⁺</small> into the pharmacophore. <strong>A4</strong> ((<em>E</em>)-Triphenyl(4-(4-(3,4-dimethylstyryl)phenoxy)butyl)phosphoniumiodide) could selectively accumulate in the mitochondria and exert excellent anticancer activity by both cell cycle arrest in G0/G1 and apoptosis induction in the mitochondrial pathway. The target mitochondria drug design is an effective strategy for exploiting the drug potential for cancer therapy.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 1","pages":" 92-98"},"PeriodicalIF":2.7,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142826076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HAase/GSH dual-responsive mesoporous organosilica nanoparticles for synergistic photodynamic/photothermal/pharmacological antibacterial therapy†","authors":"Wei Guo, Yunhan Huang, Jingrui Chang, Xinyu Wang and Bo Lu","doi":"10.1039/D4NJ03287J","DOIUrl":"https://doi.org/10.1039/D4NJ03287J","url":null,"abstract":"<p >Mesoporous organosilica nanoparticles (MONs) are promising drug carriers with excellent biocompatibility and biodegradability. In the context of the bacterial infection microenvironment, a hyaluronidase (HAase)/glutathione (GSH) dual-responsive degradable nanoplatform based on MON (ICG/CIP@MON@PEI-HA) has been developed for the multimodal treatment of bacterial infection. In this work, ciprofloxacin (CIP) and indocyanine green (ICG) are physically adsorbed into the MON, polyethyleneimine (PEI) is electrostatically adsorbed onto the MON surface, and hyaluronic acid (HA) is grafted onto the amino groups of PEI <em>via</em> the amide bonds. The overexpression of HAase at bacterial infection sites enables HA shell degradation, and positively charged PEI is exposed, which facilitates nanoparticle binding to negatively charged bacteria. Also, owing to the protonation of amine groups, PEI is swelled in the acidic environment of bacterial infection, which favours drug release. Subsequently, overexpressed GSH breaks the disulfide bonds in the MON, triggering structural degradation that inhibits carrier accumulation and accelerates drug release even further. According to <em>in vitro</em> antibacterial evaluations, the antibacterial effect can be enhanced to 100% when phototherapy and pharmaceutical therapy are combined. <em>In vitro</em> cytotoxicity assays have demonstrated that ICG/CIP@MON@PEI-HA possesses excellent biocompatibility. Therefore, this study offers a potential approach for developing biodegradable nanoplatforms for the combined treatment of bacterial infection.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 46","pages":" 19462-19471"},"PeriodicalIF":2.7,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study of luminescent Cd-MOF and Cd-MOF@HNT nanomaterials for the detection of hydroxyl-functionalized nitroaromatic compounds†","authors":"Kushal Arya, Sanjay Mehra, Ajay Kumar, Vaneet Saini, Arvind Kumar, Surinder Kumar Mehta and Ramesh Kataria","doi":"10.1039/D4NJ04352A","DOIUrl":"https://doi.org/10.1039/D4NJ04352A","url":null,"abstract":"<p >Metal–organic frameworks (MOFs) are emerging as a key solution for detecting and adsorbing hazardous nitroaromatic compounds, driven by environmental and security concerns. In this paper, a high pH and water-stable fluorescent MOF (PUC-10) with distorted pentagonal bipyramidal geometry and interesting <em>hcb</em> topology was prepared by a solvothermal method. Furthermore, a PUC-10 NP based composite (PUC-10@HNT) was fabricated and applied for the sensitive detection of hydroxyl group-containing nitroaromatic compounds (NACs). In particular, trinitrophenol (TNP), dinitrophenol (DNP) and <em>para</em>-nitrophenol (4-NP) rapidly quench the fluorescence of PUC-10@HNT, with a detection limit of 0.027 μM, 0.031 μM and 0.036 μM, respectively. The sensing ability of PUC-10 and PUC-10@HNT was compared to signify the composite formation. This method effectively analyzes the respective NACs in natural water and a Whatman-paper-strip sensing element was also developed for efficient visual detection of analytes. Moreover, PUC-10@HNT showed excellent recyclability over four cycles. Based on the DFT calculations, zeta-potential, absorption and photoluminescence spectra of the analytes and probe, the fluorescence quenching mechanism was analyzed and found to be due to a combination of PET, FRET, and competitive light absorption between the analytes and PUC-10@HNT.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 47","pages":" 20018-20033"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142761647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing photovoltaic properties of organic solar cells through core alteration of methyl-substituted bithiophene-based small molecule acceptors†","authors":"Smiti Rani Bora and Dhruba Jyoti Kalita","doi":"10.1039/D4NJ04211E","DOIUrl":"https://doi.org/10.1039/D4NJ04211E","url":null,"abstract":"<p >In organic solar cells (OSCs), acceptors have emerged as a significant class of photoactive materials. On account of the already reported compound PTT-FBTz, five D<small>₁</small>–π–D<small>₂</small>–π–D<small>₁</small> type acceptors (C1–C5) have been designed using methyl-substituted bithiophene as the common terminal unit (D<small>₁</small>) and five different core units (π–D<small>₂</small>–π). Both density functional theory (DFT) and its counterpart, time-dependent density functional theory (TD-DFT) approaches, were utilized to thoroughly examine the influence of core engineering on optoelectronic as well as photovoltaic properties. The results suggest that alteration of the core unit enhanced the designed acceptor molecules’ performance. Besides, the electron-accepting nature of the designed compounds is confirmed from the calculated reorganization energy (<em>λ</em>) values. Additionally, it is clear from the designed compounds’ absorption properties that compound C5 has higher <em>λ</em><small>_max</small> values in both phases. Based on the D/A complex properties, the designed A1/C1–C5 complexes, can boost the separation of charge carriers at the donor/acceptor junction. Besides, due to their photovoltaic performance, complex A1/C5 achieving a PCE of 24.65%, stands out as the most favorable option for OSC fabrication.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 47","pages":" 19963-19973"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142761642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fe3O4@C magnetite nanocomposite: an artificial peroxidase nanozyme for the development of a colorimetric glucose biosensor†","authors":"Hoang V. Tran, Nghia D. Nguyen, Anh-Tuan Le, Luyen T. Tran, Thu D. Le and Chinh D. Huynh","doi":"10.1039/D4NJ03808H","DOIUrl":"https://doi.org/10.1039/D4NJ03808H","url":null,"abstract":"<p >Horseradish peroxidase (HRP), a natural enzyme, consists of a Fe<small>^III</small> ion, which plays the role as an active center of the enzyme, wherein the binding of H<small>₂</small>O<small>₂</small> to the Fe<small>^III</small> ion creates an octahedral configuration around Fe<small>^III</small>, leading to the decomposition of the –O–O– bond of H<small>₂</small>O<small>₂</small>. Based on this considering, here, we propose amorphous-carbon-functionalized Fe<small>₃</small>O<small>₄</small> nanoparticles (Fe<small>₃</small>O<small>₄</small>@C) that serve as a peroxidase nanozyme with Fe<small>^III</small> and exhibits peroxidase-like catalytic activity. In this work, Fe<small>₃</small>O<small>₄</small>@C was synthesized <em>via</em> a simple hydrothermal process from a suspension of Fe<small>₃</small>O<small>₄</small> nanoparticles and glucose solution. The peroxidase-mimicking activity of Fe<small>₃</small>O<small>₄</small>@C was demonstrated following the Michaelis–Menten and Lineweaver–Burk equations of the enzymatic model. At optimized conditions, Fe<small>₃</small>O<small>₄</small>@C showed stronger catalytic activity than HRP, with Michaelis–Menten constants (<em>K</em><small>_m</small>) 0.052 mM and 0.004 mM for the H<small>₂</small>O<small>₂</small> substrate and TMB co-substrate, respectively. Using Fe<small>₃</small>O<small>₄</small>@C as a replacement for HRP, a colorimetric chemical sensor for H<small>₂</small>O<small>₂</small> sensing and a colorimetric biosensor for glucose detection were constructed, and they exhibited high selectivity and sensitivity with an LOD of 20 μM for H<small>₂</small>O<small>₂</small> and 40 μM for glucose. The applicability of the glucose biosensor was also tested in real samples, including a 5% intravenous glucose solution and human blood serum, revealing high recovery rates.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 47","pages":" 20007-20017"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142761646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A green method for the synthesis of lubricating ester oil using a bi-functional ionic liquid†","authors":"Yanan Wang, Qilong Zhao, Jun Yin, Huaigang Su, Hongyuan Yu and Wenjing Lou","doi":"10.1039/D4NJ03618B","DOIUrl":"https://doi.org/10.1039/D4NJ03618B","url":null,"abstract":"<p >A bi-functional ionic liquid 1-(benzotriazole-1-methylene)-3-methylimidazole bis(2-ethylhexyl) phosphate ([BTAMIM][DEHP]) was prepared. It exhibited high activity and selectivity for the esterification of pentaerythritol with caproic acid to pentaerythritol tetra-hexanoate (PETH). Meanwhile, the friction reduction and anti-wear performance of pentaerythritol tetra-hexanoate were improved significantly by [BTAMIM][DEHP].</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 45","pages":" 19040-19043"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/nj/d4nj03618b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142672317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly efficient extraction of alkaloids via bio-derived ionic liquids for complex wound repair†","authors":"Tianqi Liu, Lin Xie, Hailiang Xiao, De Bai, Ying Liu, Jichuan Zhang and Jiaheng Zhang","doi":"10.1039/D4NJ03289F","DOIUrl":"https://doi.org/10.1039/D4NJ03289F","url":null,"abstract":"<p > <em>Coptis chinensis</em> alkaloids have shown remarkable medical value in recent decades, however, their extraction efficiency is limited by the high cost and poor safety of traditional routes. In this study, a series of bio-based ionic liquids (ILs) were successfully prepared through an ion-exchange reaction using precursors derived from organic acids and alkaloids, which significantly enhanced the extraction of alkaloids from <em>Coptis chinensis</em>. By utilizing techniques of electron microscopy and analog computation, the novel extraction method is shown to be twice as effective as the traditional water extraction method. Furthermore, cellular level experiments verify the antimicrobial, anti-inflammatory and antioxidant properties, and animal experiments indicate that the IL-derived extraction route can boost the healing efficiency of complex wounds by three times. This study not only broadens the application of bio-based ionic liquids in plant extraction, but also delivers a low-cost, simple-to-use biologic agent for skin repair, demonstrating its great potential for application.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 48","pages":" 20201-20211"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thiadiazolophenanthroline-based hole-transporter for durable and efficient perovskite solar cells: atomic-level insights for performance enhancement†","authors":"Zhu-Zhu Sun, Yang Li, Yunhai Zhang, Quan-Song Li and Wei-Lu Ding","doi":"10.1039/D4NJ04021J","DOIUrl":"https://doi.org/10.1039/D4NJ04021J","url":null,"abstract":"<p >Finding remarkable hole-transporting materials (HTMs) for perovskite solar cells (PSCs) is crucial but challenging, and rationally regulating the acceptor structure is one of the most effective strategies. In this work, a novel electron-withdrawing moiety of thiadiazolophenanthroline (TPT) was first exploited as the acceptor structure of donor–acceptor–donor (D–A–D)-type HTMs. The isolated molecular and interfacial properties of TPT-based HTMs (SM-4) were methodically investigated by comparing with the simulated results of benzothiadiazole (BT, SM-1) and phenanthrothiadiazole (PT, SM-2) acceptors. Theoretical simulations manifest that SM-4 displays a more negative HOMO energy and larger hole mobility than SM-1 and SM-2. The higher mobility of SM-4 is derived from the larger hole transfer integral due to easier intermolecular orbital overlap. Moreover, the better optical excitation property, smaller exciton binding energy, and profitable solubility and stability are shown for SM-4. Furthermore, interfacial calculations reveal that advantageous photon-induced excitation dissociation can be anticipated at the interface because of greater interfacial charge redistribution and more suitable energy levels. Overall, our simulations suggest that the designed TPT-based acceptor molecule holds great promise as a potential HTM candidate, providing support for more efficient PSCs.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 47","pages":" 20051-20060"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142761650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of high-toughness PAM-Gel/CNTs-RGO hydrogel and its electromagnetic shielding properties†","authors":"Kunlan Diao, Teng Zhou, Jiajia Du, Yuhuan Xu and Daohai Zhang","doi":"10.1039/D4NJ03558E","DOIUrl":"https://doi.org/10.1039/D4NJ03558E","url":null,"abstract":"<p >With the rapid development of the electromagnetic (EMI) industry, EMI pollution has become a serious problem. In this work, the effect of filler content on electromagnetic shielding performance was studied by heat-induced polymerization of acrylamide (AM) and gelatin (Gel) to form double-mesh hydrogel (PAM-Gel), and then, different contents of carbon nanotubes (CNTs) and reduced graphene oxide (RGO) were added. Finally, a one-dimensional/two-dimensional (1D/2D) PAM-Gel/CNTs-RGO heterostructured van der Waals hydrogel was prepared by mixing CNTs with RGO. The experimental results showed that compared with PAM-Gel/CNTs hydrogel or PAM-Gel/RGO hydrogel, the mixed PAM-Gel/CNTs-RGO hydrogel showed the best EMI shielding performance. In general, the EMI shielding effect of PAM-Gel/CNTs-RGO-1 : 1 in the X-band with a thickness of 4 mm was as high as 45.14 dB, compressive stress–strain was 18.45 MPa and 95.90%, water content was 75.74%, and conductivity was 1.12 s m<small>⁻¹</small>.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 45","pages":" 19325-19336"},"PeriodicalIF":2.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142672193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}