CardioVascular and Interventional Radiology最新文献

{"title":"Percutaneous Transhepatic Intratumoural Glue Embolization: A Targeted Technique for Lung Shunt Reduction Before Y-90 Radioembolization.","authors":"Saurabh Kumar, Apoorva Batra","doi":"10.1007/s00270-026-04491-7","DOIUrl":"10.1007/s00270-026-04491-7","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2176-2179"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148041271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who is Afraid of the Gallbladder? Case Series of Unmitigated Pericholecystic Microwave Ablations of Liver Tumours with Pictorial Review.","authors":"Umberto Pisano, David Hunter Kay","doi":"10.1007/s00270-026-04415-5","DOIUrl":"10.1007/s00270-026-04415-5","url":null,"abstract":"<p><strong>Purpose: </strong>Thermal ablation of liver tumours is widely established. A location in vicinity of the gallbladder (GB) usually causes apprehension. Our intention was to gather data from our day-to-day practice to assess whether pericholecystic tumours can be ablated safely without protective measures.</p><p><strong>Materials and methods: </strong>Retrospective review of patient series undergoing microwave ablation of primary and secondary pericholecystic liver tumours (segments IVb-V) without hydro-pneumodissection between September 2018 and September 2025, in which the ablation zone encompassed the GB wall. Outcomes are technical success (> 5 mm safety margins), complication rate, hospital stay length, postoperative pain, modified gastrointestinal symptoms rating scale (mGSRS) score at 24h, rate of 30-day hospital readmission 3-, 6-, 12-month local tumour progression-free survival (LTPFS).</p><p><strong>Results: </strong>Forty-eight patients were included; 34 (70.8%) were males. Average age was 67 years (SD ± 10.2). Hepatocellular carcinoma was the most common diagnosis. Twenty-six (54.2%) procedures were performed on a single lesion near GB. Technical success was 100%. No severe complications were seen. Average pain score was 1.9 (SD ± 1.8; median 1, IQR 0.75-2.25), and mGSRS score was 8.6 (SD ± 5.8; median 7.5 IQR 4-11); average hospital stay length was 1.9 days (SD ± 2.3; median 1 day; IQR 1-2 days). Four patients (8.3%) required readmission: 1 (2.1%) due to delayed cholecystitis (treated conservatively) and 3 (6.3%) due to pain, but no additional intervention. 3-, 6-, 12-month LTPFS was 94%, 89% and 80%.</p><p><strong>Conclusion: </strong>The incidence of GB injury was low in this series, and the procedures were well tolerated. A protective hydro- or pneumodissection was found to be not essential.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2084-2094"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Scores are not Enough: Depression, Anxiety, and Patient-Perceived Treatment Response in Venous-Origin Chronic Pelvic Pain.","authors":"Neil M Khilnani","doi":"10.1007/s00270-026-04579-0","DOIUrl":"10.1007/s00270-026-04579-0","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2127-2128"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curative-Intent Cryoablation for Bone Metastases: Study Protocol for BOREALIS, a Prospective Multicentre Observational Investigation.","authors":"Roberto Luigi Cazzato, Xavier Buy, Fernando Gomez, Frederic Deschamps, Dirk Arnold, Dimitrios Filippiadis, Jack Jennings, Niklaus Schaefer, Olivier Schneegans, Georgia Tsoumakidou, Bleranda Zeka, Claire Poulet, Nathalie Kaufmann, Jean Palussiere, Afshin Gangi","doi":"10.1007/s00270-026-04550-z","DOIUrl":"10.1007/s00270-026-04550-z","url":null,"abstract":"<p><strong>Purpose: </strong>Cryoablation (CA) is a well-established, safe and effective palliative treatment for painful bone metastases (BM). Data exploring its curative potential (i.e. radical clearing of the target lesion) is however very scarce, mostly coming from small retrospective studies. The BOne metastases REgistry for patients undergoing cryoAbLation with curatIve purpoSe (BOREALIS) aims to address this shortcoming by collecting prospective, multicentric real-world data on the outcomes of curative-intent CA for bone metastases.</p><p><strong>Methods: </strong>BOREALIS is an observational cohort study designed to follow for 1 year up to 50 participants with BM (< 5 cm) from oligometastatic or bone oligo-progressive disease treated with curative-intent CA. The primary outcome measure is the 12-months local progression-free survival rate, assessed per lesion using the newly developed BOREALIS tumour response criteria. Secondary outcome measures include complete response rate, fracture-free, progression-free, and overall survival; safety; patient-reported pain; and health-related quality of life (HRQoL). The study will also evaluate the feasibility of a comprehensive procedure integrating, when indicated, biopsy and bone consolidation within the same CA session. Results will be reported using mainly descriptive statistics. Patient enrolment opened in April 2025.</p><p><strong>Conclusion: </strong>BOREALIS intends to provide insights into the effectiveness of curative-intent CA for BM to inform the development of future clinical guidelines. BOREALIS is registered on ClinicalTrial.gov (NCT06480955).</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2153-2161"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13642440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CIRSE Launches \"Access to Care\" Initiative to Strengthen Interventional Radiology Access in Africa and Eastern Europe.","authors":"Philippe L Pereira, Vincent Vidal, Christoph A Binkert, Birgit Slijepčević, Fabian M Laage Gaupp","doi":"10.1007/s00270-026-04542-z","DOIUrl":"10.1007/s00270-026-04542-z","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"1919-1921"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Feasibility Study of Trans-Arterial Chemoembolization as a First-Line Treatment for Locally Advanced Breast Cancer.","authors":"Ryusuke Kuzumi, Shinichi Hori, Atsushi Hori, Masato Takeuchi, Ikuo Dejima, Tatsuya Nakamura","doi":"10.1007/s00270-026-04471-x","DOIUrl":"10.1007/s00270-026-04471-x","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility of transarterial chemoembolization (TACE) for locally advanced breast cancer (LABC).</p><p><strong>Materials and methods: </strong>A total of 31 sequential patients with previously untreated LABC in Stages III or IV were evaluated retrospectively. Selective microcatheter insertion was performed on all branches angiographically identified to the breast tumours and axillary lymph node metastases. Angio-CT imaging was used to confirm the distribution of drugs within the tumour after the selective infusion of contrast material. The patients were treated with anti-neoplastic agents indicated for breast cancer therapy. Drugs were infused directly into the tumour-feeding arteries, and embolization was carried out with spherical embolic material, HepaSphere (50-100 µm). After the initial treatment, additional treatments were repeated as needed. The primary outcome measure was the local response of the primary tumours and lymph node metastases at 1, 3, 6, and 12 months after the initial therapy.</p><p><strong>Results: </strong>The mean number of sessions per patient was 6.8 (range 3-23). The response rates of primary breast lesions at 1, 2, 6, and 12 months were 19%, 48%, 79%, and 70%, respectively. No major adverse events requiring therapy were reported. Local pain, bleeding, or infection were well controlled after the initial treatment. A minor complication of treatment was a skin reaction characterised by discolouration. The 1 and 2-year survival rates were 87.1% and 67.6%, respectively. The overall survival was 29.7 months. The prognostic factor most strongly affecting survival was distant metastasis.</p><p><strong>Conclusion: </strong>TACE is a safe and effective first-line treatment for LABC.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2097-2104"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13642463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147962287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision of Ablation Margin Assessment After Liver Microwave Ablation: A Head-to-Head Comparison of Visual and Software-Assisted Methods.","authors":"Coline Morisot, Idriss Chami Khazraji, Vincent Habouzit, Nicolas Magand, Bertrand Le Roy, Ilies El Boukili, Claire Boutet, Sylvain Grange, Rémi Grange","doi":"10.1007/s00270-026-04528-x","DOIUrl":"10.1007/s00270-026-04528-x","url":null,"abstract":"<p><strong>Purpose: </strong>Minimal ablative margins (MAM) are critical for local tumour control after microwave ablation, yet their assessment remains subjective. We evaluated whether software improves the precision of ablation margin assessment after liver MWA.</p><p><strong>Materials and methods: </strong>In this retrospective study, patients undergoing CT-guided liver MWA between January 2019 and January 2025 were included. Two radiologists (with 4 and 5 years of experience in abdominal imaging) assessed MAM in two steps: first by side-by-side visual comparison of pre- and post-ablation CT using anatomical landmarks, then with dedicated software providing semi-automatic 3D co-registration and margin quantification. Each method included two reading sessions per reader, six weeks apart. Precision was assessed using intraclass correlation coefficients (ICC), Cohen's kappa (κ) for categorical classification (< 5, 5-10, > 10 mm), and Bland-Altman analysis.</p><p><strong>Results: </strong>Sixty-seven patients with 87 liver tumours were included. Visual assessment showed poor reliability, with low intrareader agreement (ICC 0.10 and 0.33) and near-random interreader agreement (κ =  - 0.10; ICC - 0.05), with limits of agreement approaching 17 mm. Software-assisted assessment improved reliability, with higher intrareader ICCs (0.54 and 0.83) and improved interreader agreement (κ = 0.38; ICC = 0.54). Interreader bias decreased from - 2.84 to + 0.91 mm, and limits of agreement narrowed to - 4.10 to + 5.92 mm (p < 0.001). The median absolute interreader difference decreased from 3.0 to 1.0 mm (p < 0.001).</p><p><strong>Conclusion: </strong>Software-assisted assessment improves reliability of MAM evaluation compared with visual methods, but interreader agreement remains only fair-to-moderate; further validation is required before routine clinical adoption.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2105-2115"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13642391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DSM-TACE Versus Conventional Approaches in HCC: A Systematic Review and Meta-Analysis.","authors":"Tumolo Salvatore, Sanchez Priscila, Posa Alessandro, Vingiani Vincenzo, Bilhim Tiago, Iezzi Roberto","doi":"10.1007/s00270-026-04595-0","DOIUrl":"10.1007/s00270-026-04595-0","url":null,"abstract":"<p><strong>Purpose: </strong>To perform a systematic review and meta-analysis comparing efficacy and the safety profile of Degradable Starch Microspheres TACE (DSM-TACE) with conventional treatments (cTACE and DEB-TACE) in patients with Hepatocellular carcinoma (HCC).</p><p><strong>Materials and methods: </strong>Comparative studies (including randomized controlled trials -RCTs- and observational studies) reporting at least one of the following outcomes were included and considered for statistical analysis: Tumor response according to mRECIST criteria, Overall Survival (OS), Adverse Events (AEs), increase of ALT and AST levels. Risk Ratios were calculated using random-effects models. Survival analyses and Hazard Ratios were derived using reconstructed individual patient data.</p><p><strong>Results: </strong>6/180 articles met inclusion criteria, including 1 RCT and 5 observational studies. Tumor response was comparable between DSM-TACE and control groups, without significant differences in the pooled analyses. DSM-TACE was not associated with a significant improvement in OS compared with conventional treatments (HR = 1.04; 95% CI: 0.73-1.49; p = 0.690). AEs were only assessed narratively, due to insufficient homogeneous data for a pooled quantitative analysis. Restricting the analysis to DSM-TACE and cTACE, the analyses of post-procedural ALT and AST levels suggested a trend toward lower enzyme elevations with DSM-TACE (ALT: β=30.3, p=0.163; AST: β=44.3, p=0.141), although differences were not statistically significant.</p><p><strong>Conclusion: </strong>DSM-TACE demonstrates radiological efficacy and an OS comparable to conventional treatments, with a trend toward a more favorable safety profile. DSM-TACE may represent an exploratory option within a personalized therapeutic strategy, although statistical significance was not demonstrated. Further well-designed clinical trials are required to better define its clinical role.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"1949-1962"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fear Leads to Failure and Failure Leads to Fear.","authors":"Julien Garnon, Julia Weiss","doi":"10.1007/s00270-026-04462-y","DOIUrl":"10.1007/s00270-026-04462-y","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2095-2096"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Specific-Activity Resin Yttrium-90 Radiation Segmentectomy of Hepatocellular Carcinoma: A Study of Efficacy, Safety, and Dosimetry Considerations.","authors":"Alexander Villalobos, Ali Alfrasiabi, Paolo Varela, Roshan Valentine, Bahareh Gholami, Haneyeh Shahbazian, Andrew M Moon, Neil Shah, Johannes L Du Pisanie, Hyeon Yu, David M Mauro, Nima Kokabi","doi":"10.1007/s00270-026-04553-w","DOIUrl":"10.1007/s00270-026-04553-w","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate efficacy, safety, particle density, and dosimetry of high-specific-activity (HSA) resin-based (RB) Yttrium-90 radiation segmentectomy (Y90-RS) for hepatocellular carcinoma (HCC).</p><p><strong>Materials and methods: </strong>All 4- and 5-day pre-calibration (DPC) Y90-RS performed on patients with HCC were retrospectively analyzed at a single-center between July 2023 and May 2025. Tumor response and adverse events (AE) were assessed using mRECIST and CTCAE v5 at 3, 6, and 12-months. Voxel-based dosimetry analysis on post-Y90 SPECT/CT was performed to create tumor dose (TD) volume histograms and particle density (PD) assessment. Receiver Operating Characteristic (ROC) curves were used to evaluate the dose thresholds able to predict a tumor complete response (CR) in relation to TD and PD. Variable differences were assessed with a Mann-Whitney U Test and the Chi-Square tests.</p><p><strong>Results: </strong>Sixty patients (63 tumors) underwent HSA RB Y90-RS (62% 4-DPC). The cohort was 62% male, median age 66 years (IQR, 62-71), with 95% solitary HCC. At 3 months, tumor control was 100% and CR was 79%. Treatment was well tolerated, with only two patients developing grade 3 AEs. The median delivered mean TD was 423 Gy (IQR 316-712), with the CR cohort showing higher mean TD than the incomplete response cohort (546 Gy vs. 299 Gy; p = 0.0003). Tumor PD and Mean TD thresholds predicting 3-month CR were 45,494 microspheres/mL (AUC = 0.80) and 416 Gy (AUC = 0.83), respectively. D95 TD of > 245 Gy was associated with CR (AUC = 0.81).</p><p><strong>Conclusion: </strong>Curative intent ablative Y90-RS of HCC with HSA RB microspheres is efficacious and well tolerated. Mean TD threshold of ≥ 416 Gy and tumor-PD of ≥ 45,494 microspheres/mL were associated with 3-month tumor CR.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"2072-2083"},"PeriodicalIF":3.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148617978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}