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Canadian Journal of Diabetes最新文献

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Patterns in the Incidence (1994–2018) and Prevalence (2004–2018) of Type 1 and Type 2 Diabetes Among Nova Scotian Youth Under 20 Years of Age 新斯科舍省20岁以下青年1型和2型糖尿病发病率（1994-2018）和患病率（2004-2018）的模式
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-12-01 Epub Date: 2025-09-24 DOI: 10.1016/j.jcjd.2025.09.003
Elizabeth A. Cummings MD , Teresa Pinto MD , O. Maya Rao BSc , Pamela Talbot MSc
{"title":"Patterns in the Incidence (1994–2018) and Prevalence (2004–2018) of Type 1 and Type 2 Diabetes Among Nova Scotian Youth Under 20 Years of Age","authors":"Elizabeth A. Cummings MD ,&nbsp;Teresa Pinto MD ,&nbsp;O. Maya Rao BSc ,&nbsp;Pamela Talbot MSc","doi":"10.1016/j.jcjd.2025.09.003","DOIUrl":"10.1016/j.jcjd.2025.09.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Rates of type 1 and type 2 diabetes (T1D and T2D, respectively) in youth may be increasing globally, but findings vary across populations. We aimed to determine changes in incidence and prevalence of T1D and T2D over a 25-year period (1994–2018) in youth &lt;20 years of age in Nova Scotia (NS).</div></div><div><h3>Methods</h3><div>This population-based descriptive epidemiologic study used the Diabetes Care Program of the NS Registry that prospectively collects population-based records for all cases of diabetes in youth. Incidence (1994–2018) and prevalence (2004–2018) of T1D and T2D were calculated per 100,000 for 5-year periods using national census population estimates (0–19 years) and analyzed by sex, age group, and rural vs urban residence.</div></div><div><h3>Results</h3><div>Incidence (95% confidence interval [CI]) of T1D rose from 26.4 (23.0–29.7) in 1994–1998 to 37.9 (33.3–42.6) in 2014–2018 in 0–14-year-olds. The average annual increase was 0.7 (0.43–0.97) per 100,000. Incidence appeared to plateau after 2008, except in 10–14-year-olds, where it continued to rise. Prevalence (95% CI) of T1D for youth 0–19 years of age increased from 288.4 (278.2–298.6) per 100,000 in 2004–2008 to 333.4 (321.7–345.1) in 2014–2018. Incidence of T2D in 10–19-year-olds rose from 2.9 per 100,000 in 1994–1998 to 13.0 per 100,000 in 2014–2018 and was higher in females and youth living in rural areas.</div></div><div><h3>Conclusions</h3><div>Incidence of both types of diabetes in NS is high and continuing to rise. Patterns in T1D incidence align with those reported in other high-incidence populations. Incidence and prevalence of T2D in NS youth were similar to or higher than most previous reports despite the lower ethnic diversity in NS compared with other high-incidence populations.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 8","pages":"Pages 461-469.e3"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145180770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tenfold Insulin Icodec Overdose 胰岛素过量10倍：1例报告。
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-12-01 Epub Date: 2025-07-25 DOI: 10.1016/j.jcjd.2025.07.005
Kara Hawker MD , Justin Morein MD , Gurleen Gill MD , Irena Druce MD, MSc
{"title":"Tenfold Insulin Icodec Overdose","authors":"Kara Hawker MD ,&nbsp;Justin Morein MD ,&nbsp;Gurleen Gill MD ,&nbsp;Irena Druce MD, MSc","doi":"10.1016/j.jcjd.2025.07.005","DOIUrl":"10.1016/j.jcjd.2025.07.005","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 8","pages":"Pages 470-472"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144736068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Group Exercise Classes as a Source of Motivation and Support for Those With Diabetes---a Silver Bullet? 团体运动课程作为糖尿病患者动力和支持的来源——灵丹妙药？
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-12-01 Epub Date: 2025-09-09 DOI: 10.1016/j.jcjd.2025.08.005
Lindsay S. Nagamatsu PhD , Joyla A. Furlano PhD , Samantha Marshall MSc , Olivia Ghosh-Swaby PhD , Gillian Rutherford , Jane Yardley PhD
{"title":"The Role of Group Exercise Classes as a Source of Motivation and Support for Those With Diabetes---a Silver Bullet?","authors":"Lindsay S. Nagamatsu PhD ,&nbsp;Joyla A. Furlano PhD ,&nbsp;Samantha Marshall MSc ,&nbsp;Olivia Ghosh-Swaby PhD ,&nbsp;Gillian Rutherford ,&nbsp;Jane Yardley PhD","doi":"10.1016/j.jcjd.2025.08.005","DOIUrl":"10.1016/j.jcjd.2025.08.005","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 8","pages":"Pages 473-475"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can a Combined Epigenetic-Biomarker Score Supplant Chronologic Age as an Independent Determinant of Incident Death in Adults With Dysglycemia 表观遗传-生物标志物联合评分能否取代年代学年龄作为成人血糖异常死亡事件的独立决定因素？
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-12-01 Epub Date: 2025-08-05 DOI: 10.1016/j.jcjd.2025.07.006
Hertzel C. Gerstein MD, MSc , Guillaume Pare MD, MSc , Keyun Zhou MSc , Serena Yang MSc , Michael Chong PhD , Gregory R. Steinberg PhD , Shun Fu Lee PhD
{"title":"Can a Combined Epigenetic-Biomarker Score Supplant Chronologic Age as an Independent Determinant of Incident Death in Adults With Dysglycemia","authors":"Hertzel C. Gerstein MD, MSc ,&nbsp;Guillaume Pare MD, MSc ,&nbsp;Keyun Zhou MSc ,&nbsp;Serena Yang MSc ,&nbsp;Michael Chong PhD ,&nbsp;Gregory R. Steinberg PhD ,&nbsp;Shun Fu Lee PhD","doi":"10.1016/j.jcjd.2025.07.006","DOIUrl":"10.1016/j.jcjd.2025.07.006","url":null,"abstract":"<div><h3>Objectives</h3><div>Diabetes and prediabetes are associated with premature death and are recognized as conditions of accelerated biologic aging. To date, the best measurement of biologic age is chronologic age. Measures of biologic age that can replace chronologic age as a predictor of death can better approximate risk in affected individuals.</div></div><div><h3>Methods</h3><div>The relationship between 238 biomarkers, epigenetic age scores, and incident death was analyzed in 2,755 participants (mean age 63.7±8 years) in the Outcomes Reduction with an Initial Glargine Intervention (ORIGIN) trial. Independent biomarkers for death identified using Cox models with forward selection were used to derive a biomarker risk score, which, after validation, was combined with epigenetic scores. Hazards for death per standard deviation higher epigenetic-biomarker score, chronologic age, or the age after adjustment for the score were estimated, and the respective β coefficients were compared.</div></div><div><h3>Results</h3><div>Four hundred eighty-one participants died during a median follow-up of 6.2 years. Each standard deviation higher age increased the hazard of death 1.69-fold (95% confidence interval [CI] 1.58 to 1.81, β=0.53). When 11 independent death biomarkers were combined with 3 epigenetic risk scores to yield an epigenetic-biomarker score, each standard deviation higher score increased the hazard of death 3.27-fold (95% CI 2.90 to 3.68). Adding standardized age to this model yielded a β coefficient for age of 0.00 (p=0.93). C statistics for the epigenetic-biomarker score alone and age alone were 0.77 (95% CI 0.74 to 0.78) and 0.66 (95% CI 0.63 to 0.68), respectively (p&lt;0.001 for the difference).</div></div><div><h3>Conclusion</h3><div>An epigenetic-biomarker risk score is a better predictor of death than chronologic age.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 8","pages":"Pages 424-430.e8"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Interpretive Description of Participant Experiences Doing Resistance Exercise for Post-Menopausal Females With Type 1 Diabetes 绝经后女性1型糖尿病患者抗阻运动的解释性描述
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-11-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jcjd.2025.10.090
JESSICA LOGAN , NORMAND BOULÉ , JANE YARDLEY
{"title":"An Interpretive Description of Participant Experiences Doing Resistance Exercise for Post-Menopausal Females With Type 1 Diabetes","authors":"JESSICA LOGAN ,&nbsp;NORMAND BOULÉ ,&nbsp;JANE YARDLEY","doi":"10.1016/j.jcjd.2025.10.090","DOIUrl":"10.1016/j.jcjd.2025.10.090","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 7","pages":"Page S35"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yukon Experiences in Management of Type 1 Diabetes: Patient Perspectives 育空地区1型糖尿病管理经验：患者视角
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-11-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jcjd.2025.10.005
MARNEY PARADIS , LIRIS SMITH , RUTH NIELSEN
{"title":"Yukon Experiences in Management of Type 1 Diabetes: Patient Perspectives","authors":"MARNEY PARADIS ,&nbsp;LIRIS SMITH ,&nbsp;RUTH NIELSEN","doi":"10.1016/j.jcjd.2025.10.005","DOIUrl":"10.1016/j.jcjd.2025.10.005","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 7","pages":"Page S2"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indigenous-Led Lower Limb Preservation Initiative 原住民主导的下肢保护倡议
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-11-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jcjd.2025.10.081
SAMANTHA LASCELLES , IRENE SAMUEL
{"title":"Indigenous-Led Lower Limb Preservation Initiative","authors":"SAMANTHA LASCELLES ,&nbsp;IRENE SAMUEL","doi":"10.1016/j.jcjd.2025.10.081","DOIUrl":"10.1016/j.jcjd.2025.10.081","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 7","pages":"Page S32"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Searching for Value-Based Healthcare Approaches Towards Diabetic Foot Care and Limb Preservation: Challenges With a Scoping Review 寻找以价值为基础的医疗保健方法，以糖尿病足护理和肢体保存：挑战与范围审查
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-11-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jcjd.2025.10.020
JAMES BOWEN , JOANNA M. BIELECKI , SUJA MATHEW , K. PATRICK LAFFIN , LOLA OYEFESO , AKHANSHA FERNANDO , MAJIDA MOHAMMED , ALISHA HANIF , KEVIN ZHAN , DEENA HASSAN , VALERIA RAC
{"title":"Searching for Value-Based Healthcare Approaches Towards Diabetic Foot Care and Limb Preservation: Challenges With a Scoping Review","authors":"JAMES BOWEN ,&nbsp;JOANNA M. BIELECKI ,&nbsp;SUJA MATHEW ,&nbsp;K. PATRICK LAFFIN ,&nbsp;LOLA OYEFESO ,&nbsp;AKHANSHA FERNANDO ,&nbsp;MAJIDA MOHAMMED ,&nbsp;ALISHA HANIF ,&nbsp;KEVIN ZHAN ,&nbsp;DEENA HASSAN ,&nbsp;VALERIA RAC","doi":"10.1016/j.jcjd.2025.10.020","DOIUrl":"10.1016/j.jcjd.2025.10.020","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 7","pages":"Page S8"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145595065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kidney Protection in Diabetes: What Primary Care Clinicians Need to Know Now 糖尿病的肾脏保护：初级保健临床医生现在需要知道什么
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-11-01 Epub Date: 2025-12-26 DOI: 10.1016/j.jcjd.2025.12.005
Alan Kaplan MD, CCFP(EM), FCFP
{"title":"Kidney Protection in Diabetes: What Primary Care Clinicians Need to Know Now","authors":"Alan Kaplan MD, CCFP(EM), FCFP","doi":"10.1016/j.jcjd.2025.12.005","DOIUrl":"10.1016/j.jcjd.2025.12.005","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 ","pages":"Pages 1-2"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BCL-XL as Potential Drug Target in Senescent Human Beta Cells During Type 1 Diabetes BCL-XL作为1型糖尿病患者衰老β细胞的潜在药物靶点
IF 2.6 4区 医学
Canadian Journal of Diabetes Pub Date : 2025-11-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jcjd.2025.10.093
NAYARA RAMPAZZO MORELLI , PETER THOMPSON
{"title":"BCL-XL as Potential Drug Target in Senescent Human Beta Cells During Type 1 Diabetes","authors":"NAYARA RAMPAZZO MORELLI ,&nbsp;PETER THOMPSON","doi":"10.1016/j.jcjd.2025.10.093","DOIUrl":"10.1016/j.jcjd.2025.10.093","url":null,"abstract":"","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"49 7","pages":"Page S36"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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