{"title":"DePoly","authors":"None Mark Peplow, special to C&EN","doi":"10.1021/cen-10137-cover4","DOIUrl":"https://doi.org/10.1021/cen-10137-cover4","url":null,"abstract":"In 2018, reports in the mainstream media about plastic pollution reached a crescendo. Dead whales with bellies full of plastic trash appeared on the pages of National Geographic . Scientists voiced concerns about microplastics in our food, water, and air. Images of tropical bays choked with plastic debris offered visceral proof that our waste management systems were failing. Samantha Anderson was a PhD student at the Swiss Federal Institute of Technology, Lausanne (EPFL), at the time , and she vividly remembers how these reports spurred her and her colleagues to take action. “We just decided that we were going to try and tackle it with chemistry and chemical engineering, because that’s what we knew,” she says. With her EPFL lab mates Christopher Ireland and Bardiya Valizadeh, Anderson developed a process for recycling polyethylene terephthalate (PET) in complex waste streams that most recyclers reject. In 2020, the trio cofounded DePoly to","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"55 26","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136283227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Industry profits evaporate in Europe","authors":"None Alex Scott","doi":"10.1021/cen-10137-buscon2","DOIUrl":"https://doi.org/10.1021/cen-10137-buscon2","url":null,"abstract":"Many of Europe’s biggest chemical producers—including the German firms BASF, Covestro, Evonik Industries, and Lanxess—have reported declining sales and net losses for the third quarter. Europe’s chemical sector is now firmly in cost-cutting mode, and some companies are closing manufacturing plants because of ongoing soft demand for their products. BASF, still the world’s largest chemical company, recorded a loss of $264 million for the third quarter, compared with earnings of $962 million in the year-earlier period, and sales of $16.2 billion, down 28%. The German major cites considerably lower prices for products sold by its materials, chemicals, and surface technologies businesses and lower sales volumes across the board. BASF announced measures to cut costs by about $215 million annually, adding to plans to cut costs by more than $750 million per year by 2027. The firm plans to reduce its capital investments over the next 5 years by about $4.3","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sublime Systems","authors":"None Bethany Halford","doi":"10.1021/cen-10137-cover10","DOIUrl":"https://doi.org/10.1021/cen-10137-cover10","url":null,"abstract":"Cement holds the modern world together, but it lacks the allure of high-tech materials. “The stuff is gray,” says Yet-Ming Chiang , a professor of ceramics and materials science at the Massachusetts Institute of Technology. “You would be forgiven for thinking it’s kind of dull and boring.” But it’s not for Chiang and Leah Ellis, cofounders of Sublime Systems . They say finding a new way to make cement is necessary to solve one of the planet’s most pressing problems: the carbon dioxide emissions that are driving climate change. Cement, or calcium silicate hydrate, binds rocks and sand together to form concrete. Worldwide, cement companies make roughly 4 billion metric tons (t) of the stuff annually, according to the US Geological Survey. By some estimates, cement production accounts for as much as 8% of global CO 2 emissions . About half that massive belch of CO 2 is an unavoidable","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
None Diane Krone, chair, ACS Committee on Committees
{"title":"We are stronger when we listen and smarter when we share","authors":"None Diane Krone, chair, ACS Committee on Committees","doi":"10.1021/cen-10137-comment1","DOIUrl":"https://doi.org/10.1021/cen-10137-comment1","url":null,"abstract":"Council-related committees have an important role in representing the perspective of the core membership of the American Chemical Society and contribute to governance decisions. Over the past few years, the Committee on Committees (ConC) has been reviewing the committee structure and the appointment process as it strives to fulfill its mission to ensure that ACS committees are inclusive, optimally organized, resourced, and engaged. As part of our process of looking for opportunities to improve the committee system, ConC partnered with McKinley Advisors, a consulting group with knowledge of ACS and other organizations in the nonprofit space, to review current committee structures and functions and to provide actionable recommendations that support the following ideal future: The portfolio of ACS committees and related governance processes reflects the current and anticipated needs of the society. ACS committees effectively collaborate to advance the mission and vision of the society. The membership, participation, and leadership","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"25 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Solugen joins with ADM to expand biobased chemical production","authors":"None Matt Blois","doi":"10.1021/cen-10137-buscon1","DOIUrl":"https://doi.org/10.1021/cen-10137-buscon1","url":null,"abstract":"As consumer pressure and government policies push chemical firms to reduce the use of petroleum feedstocks, the green chemistry company Solugen is planning to significantly increase production of its biobased chemicals with a new facility. The new plant will be located next to an ADM complex in Marshall, Minnesota, that produces dextrose, which Solugen will use as a feedstock. Its process coproduces hydrogen peroxide and the organic acids glucaric and gluconic acid. Solugen CEO Gaurab Chakrabarti says the companies will also work together to develop new products and new markets. “ADM has a lot of customers that we could sell the glucaric acid products into,” he says. Chakrabarti cofounded Solugen in 2016 to commercialize an enzyme he discovered while in an MD-PhD program. The company has since raised more than $640 million from investors. At an existing facility in Houston, Solugen produces about 12,000 metric tons (t) per year of","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"28 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Belharra Therapeutics","authors":"None Laura Howes","doi":"10.1021/cen-10137-cover2","DOIUrl":"https://doi.org/10.1021/cen-10137-cover2","url":null,"abstract":"There are many proteins involved in making people sick, but right now, small-molecule drugs target only a small fraction of them. The San Diego–based start-up Belharra Therapeutics wants to go after a wider swath, focusing on proteins that have never been targeted by a drug. The story of Belharra, which came out of stealth at the beginning of this year, begins with Christopher Parker, a chemist at Scripps Research in California. As a postdoctoral scholar in Benjamin Cravatt’s lab at the same institute, Parker worked to build techniques for discovering pockets on proteins where drugs could bind. Parker continued that work when he started his own lab in 2018. He took the techniques he was working on to his Scripps colleague John Teijaro, an expert in immunology and persistent viral infections, and they had success binding Parker’s chemical probes to pockets on notoriously tricky immune proteins. Parker and Teijaro went","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136283226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FDA seeks to ban brominated vegetable oil","authors":"None Britt E. Erickson","doi":"10.1021/cen-10137-polcon1","DOIUrl":"https://doi.org/10.1021/cen-10137-polcon1","url":null,"abstract":"Over 50 years after determining that brominated vegetable oil (BVO) is no longer generally recognized as safe (GRAS), the US Food and Drug Administration is proposing to ban the food ingredient. BVO is not safe in food in any amount, the agency announced Nov. 2. BVO was once widely used as an emulsifier in sodas and sports drinks to keep citrus flavoring from floating to the top. Many beverage manufacturers stopped using the ingredient about 10 years ago because of health concerns. Studies in laboratory animals show increased levels of bromine in some tissues and adverse effects on the thyroid after oral exposure to the chemical. The FDA declared in 1970 that BVO is no longer GRAS, though it still allows the use of small amounts as a food additive. Since then, the agency has “continued to study it to understand any potential health impacts,” James Jones, the FDA’s deputy","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 26","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drugs versus chemicals","authors":"None Michael McCoy","doi":"10.1021/cen-10137-editorial","DOIUrl":"https://doi.org/10.1021/cen-10137-editorial","url":null,"abstract":"For most of the 9 years that C&EN has published its 10 Start-Ups to Watch feature—which appears this week on page 16—we’ve assessed drug and materials companies by separate financial standards. Start-ups focused on drugs typically raise much more money than materials firms in series A or other early funding rounds. For example, Alltrna, one of the three drug discovery firms we profiled last year, had $50 million in investor funding when it launched in 2021. The other two each raked in $100 million or more in their early investment rounds. By contrast, the chemical, agricultural, and clean technology start-ups we profiled were lucky to hit $30 million in their series A investment rounds, the stage in which companies typically transition from a promising concept to a full-fledged business. Sure, 10 companies are a small sample. But figures from the venture capital data firm PitchBook point to the same dichotomy.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"68 31","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EPA will consider regulating tire compound","authors":"None Krystal Vasquez","doi":"10.1021/cen-10137-polcon3","DOIUrl":"https://doi.org/10.1021/cen-10137-polcon3","url":null,"abstract":"The US Environmental Protection Agency has agreed to hear a petition by the Yurok, Port Gamble S’Klallam, and Puyallup tribes calling for the agency to regulate the use of N -(1,3-dimethylbutyl)- N ’-phenyl- p -phenylenediamine, known as 6PPD, in tires. The compound is linked to mass die-offs of coho salmon , which are central to the cultures, diets, and economies of these three tribes and important to other communities on the West Coast. In a response to the petition , the EPA says that in the coming months it will issue an advance notice of proposed rulemaking for 6PPD and begin gathering data to better understand the health and environmental risks associated with the chemical and a by-product, 6PPD-quinone. The agency also plans to finalize a rule under the Toxic Substances Control Act that will require manufacturers and importers of 6PPD to report any unpublished health and safety studies on","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"27 26","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DMC opens R&D facility in North Carolina","authors":"None Craig Bettenhausen","doi":"10.1021/cen-10137-buscon8","DOIUrl":"https://doi.org/10.1021/cen-10137-buscon8","url":null,"abstract":"The biobased chemicals firm DMC Biotechnologies has opened an 880 m 2 R&D site in Research Triangle, North Carolina. DMC uses custom microbes to ferment a range of nutritional ingredients and other specialty chemicals. The facility will house strain and process development labs, analytical suites, and pilot-scale fermentation lines. DMC already has a lab in Boulder, Colorado, focused on isolating products after fermentation.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"28 23","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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