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Burger's Medicinal Chemistry and Drug Discovery最新文献

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FDA‐Approved Medicines FDA批准的药物应承担的
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC264
M. Kinch
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引用次数: 0
Computational Chemistry Tools 计算化学工具
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC280
Rainer Metcalf, K. Daniel, W. Brooks, W. Guida
{"title":"Computational Chemistry Tools","authors":"Rainer Metcalf, K. Daniel, W. Brooks, W. Guida","doi":"10.1002/0471266949.BMC280","DOIUrl":"https://doi.org/10.1002/0471266949.BMC280","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"407 1","pages":"1-31"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76482373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Design and Application of Bioisosteres in Drug Design 生物异构体在药物设计中的设计与应用
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC259
N. Meanwell
{"title":"The Design and Application of Bioisosteres in Drug Design","authors":"N. Meanwell","doi":"10.1002/0471266949.BMC259","DOIUrl":"https://doi.org/10.1002/0471266949.BMC259","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"808 1","pages":"1-81"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85466090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enzymes as Drug Targets 酶作为药物靶点
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC260
T. Meek
{"title":"Enzymes as Drug Targets","authors":"T. Meek","doi":"10.1002/0471266949.BMC260","DOIUrl":"https://doi.org/10.1002/0471266949.BMC260","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87334444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cryo‐Electron Microscopy in Drug Discovery and Development: Opportunities and Challenges 低温电子显微镜在药物发现和开发中的应用:机遇与挑战
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC266
Y. Gómez-Llorente, Chuan Hong, G. Scapin
{"title":"Cryo‐Electron Microscopy in Drug Discovery and Development: Opportunities and Challenges","authors":"Y. Gómez-Llorente, Chuan Hong, G. Scapin","doi":"10.1002/0471266949.BMC266","DOIUrl":"https://doi.org/10.1002/0471266949.BMC266","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"54 1","pages":"1-32"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79817195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence in Medicinal Chemistry 药物化学中的人工智能
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC267
E. Griffen, A. Dossetter, A. Leach, Shane Montague
{"title":"Artificial Intelligence in Medicinal Chemistry","authors":"E. Griffen, A. Dossetter, A. Leach, Shane Montague","doi":"10.1002/0471266949.BMC267","DOIUrl":"https://doi.org/10.1002/0471266949.BMC267","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"2015 1","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74267658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
JAK Family Inhibitors for Autoimmune Diseases 自身免疫性疾病的JAK家族抑制剂
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC279
R. Borzilleri, Amy C. Hart, R. Moslin, J. Tokarski, Stephen T. Wrobleski
{"title":"JAK\u0000 Family Inhibitors for Autoimmune Diseases","authors":"R. Borzilleri, Amy C. Hart, R. Moslin, J. Tokarski, Stephen T. Wrobleski","doi":"10.1002/0471266949.BMC279","DOIUrl":"https://doi.org/10.1002/0471266949.BMC279","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"5 1","pages":"1-86"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78428920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Approaches for Nonalcoholic Steatohepatitis ( NASH ) 非酒精性脂肪性肝炎(NASH)的治疗方法
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-28 DOI: 10.1002/0471266949.BMC274
Ralf Glatthar, R. Arch
{"title":"Therapeutic Approaches for Nonalcoholic Steatohepatitis (\u0000 NASH\u0000 )","authors":"Ralf Glatthar, R. Arch","doi":"10.1002/0471266949.BMC274","DOIUrl":"https://doi.org/10.1002/0471266949.BMC274","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"28 1","pages":"1-71"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84327148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Confronting the COVID ‐19 Pandemic: December 2019–May 2020 应对COVID - 19大流行:2019年12月- 2020年5月
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-27 DOI: 10.1002/0471266949.BMC300
R. Dolle, D. J. Abraham, B. Norman, M. Kinch
{"title":"Confronting the\u0000 COVID\u0000 ‐19 Pandemic: December 2019–May 2020","authors":"R. Dolle, D. J. Abraham, B. Norman, M. Kinch","doi":"10.1002/0471266949.BMC300","DOIUrl":"https://doi.org/10.1002/0471266949.BMC300","url":null,"abstract":"The SARS-CoV-2 (COVID-19) pandemic was officially declared by the World Health Organization on 11 March, 2020 From the initial public reports from China in December 2019, the contagion blazed its way from ground zero in Wuhan, China into 165 countries The health disaster caught the planet by surprise At the time of this writing, 6 6 million COVID-19 cases were confirmed worldwide Central and South America are the latest hotspots Utilizing state-of-the-art science and technology, industry, government, and academic enterprises internationally are engaged in a monumental campaign to combat and eliminate the viral threat Small-molecule therapeutics discovery largely by way of drug repurposing and accelerated vaccine development are at the forefront of this campaign Within five months time, 500 unique therapeutic agents have advanced into development, >150 clinical trials initiated, and seven agents authorized for emergency use This article presents a snapshot of these activities as of 29 May 2020","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"258 1","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"2021-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76203792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Gut Microbiome 肠道微生物组
Burger's Medicinal Chemistry and Drug Discovery Pub Date : 2021-04-27 DOI: 10.1002/0471266949.BMC297
Cassandra Francella, J. Foster
{"title":"The Gut Microbiome","authors":"Cassandra Francella, J. Foster","doi":"10.1002/0471266949.BMC297","DOIUrl":"https://doi.org/10.1002/0471266949.BMC297","url":null,"abstract":"","PeriodicalId":9514,"journal":{"name":"Burger's Medicinal Chemistry and Drug Discovery","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73667735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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