Bulletin of the Chemical Society of Ethiopia最新文献_第10页

Multi-component reactions for the synthesis of pyrazolo [1,5-a]quinoline derivatives together with their cytotoxic evaluations 多组分反应合成吡唑啉[1,5-a]喹啉衍生物及其细胞毒性评价

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.14

R. M. Mohareb, Maher H.E. Helal, Amany E. Mayhoub, Amira E.M. Abdallah

{"title":"Multi-component reactions for the synthesis of pyrazolo [1,5-a]quinoline derivatives together with their cytotoxic evaluations","authors":"R. M. Mohareb, Maher H.E. Helal, Amany E. Mayhoub, Amira E.M. Abdallah","doi":"10.4314/bcse.v37i3.14","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.14","url":null,"abstract":"ABSTRACT. A new approaches for the synthesis of novel pyrazolo[1,5-a]quinazoline 8a-f and pyrazolo[1,5-a]quinazolin-6-one 10a-s and 12a-s derivatives were obtained using 4-(2-phenylhydrazono)-4H-pyrazol-3-amine derivatives 5a-f via their multi-component reactions. The later pyrazole derivatives were prepared via arylhydrazone derivatives 3a-f. The structures of the synthesized compounds were established based on their respective analytical data. On the other hand, the cytotoxic effects of the synthesized compounds were obtained against the six cancer cell lines, namely A549, HT-29, MKN-45, U87MG, SMMC-7721 and, H460 utilizing foretinib as the positive control and the standard MTT assay in vitro. The obtained results showed that compounds 8c, 8f, 10c, 10i, 10l, 10p, 10s, 12c, 12i, 12l, 12p and, 12s were the most cytotoxic compounds. In most cases the presence of the electronegative Cl group enhanced the cytotoxicity of the tested compound. \u0000 \u0000KEY WORDS: Multi-component reactions, Pyrazolo[1,5-a]quinazoline, Pyrazolo[1,5-a]quinazolin-6-one, Cytotoxicity \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 717-734. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.14","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41866626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Preparation and characterization of vernolic acid methyl ester functionalized ordered mesoporous materials 羊油酸甲酯功能化有序介孔材料的制备与表征

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.12

Y. Chebude, G. Gonfa, I. Díaz

{"title":"Preparation and characterization of vernolic acid methyl ester functionalized ordered mesoporous materials","authors":"Y. Chebude, G. Gonfa, I. Díaz","doi":"10.4314/bcse.v37i3.12","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.12","url":null,"abstract":"ABSTRACT. Vernonia oil is a naturally epoxidized triglyceride oil extracted from the seed of Vernonia galamensis, a native plant in East Africa. After hydrolysis to vernolic acid (VA) and derivatization, vernolic acid methyl ester (VAME) is synthesized and used to functionalize ordered mesoporous materials (OMM). Al-MCM-41 with Si/Al ratio of 15, pure silica SBA-15 and periodic mesoporous organosilica (PMO) are employed as supports exploring the different surface properties. Following optimization of the VAME/OMM ratios, selected samples, i.e. those with 13% VAME, were impregnated with AgNO3 in NaBH4 to obtain Ag-nanoparticles. The final AgVAME-OMM potential catalysts were characterized by transmission electron microscopy, observing an efficient loading of Ag nanoparticles in pure silica SBA-15 with VAME with 500 m2 specific surface area and 6 nm pore size. \u0000 \u0000KEY WORDS: Vernolic acid methyl ester, Vernonia oil, Functionalization, Ordered mesoporous materials, Catalysis \u0000 \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 689-702. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.12","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46132359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A simple and low-cost new procedure for synthesis of nickel(II) and cadmium(II) sulfides in situ thiourea metal–chelation precursor 一种简单、低成本的硫脲金属螯合前体原位合成硫化镍（II）和硫化镉（II）的新工艺

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.10

M. S. Refat, M. Y. El-Sayed, Ibrahim H. Alsohaimi, Hassan M. Hassan, Thamer S. Alraddadid, Sultan Akhtar

{"title":"A simple and low-cost new procedure for synthesis of nickel(II) and cadmium(II) sulfides in situ thiourea metal–chelation precursor","authors":"M. S. Refat, M. Y. El-Sayed, Ibrahim H. Alsohaimi, Hassan M. Hassan, Thamer S. Alraddadid, Sultan Akhtar","doi":"10.4314/bcse.v37i3.10","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.10","url":null,"abstract":"ABSTRACT. Nickel(II) and cadmium(II) sulfides are a promising chemical material in various advanced research areas such as solar cells, supercapacitors, catalysts, and of significant interest for their practical implementations in up to photonics and electronics. Cadmium and nickel sulfides were synthesized with stoichiometries in aqueous media at elevated temperature from Ni(NO3)2.6H2O, NiCl2.6H2O, NiSO4.6H2O, CdCl2, Cd(NO3)2.4H2O, CdSO4.8H2O and thiourea as a sulfur precursor using a direct chemical reaction. At room temperature an octahedral and tetrahedral geometries result from the reactions between different nickel(II), cadmium(II) and thiourea with the molecular formulas can be presented as [Ni(NH2CSNH2)6]X2 and [Cd(NH2CSNH2)4]X2 where X = Cl-, NO3-, SO42. The novelty of our study is precipitated yellow cadmium sulfide and black nickel sulfide at elevated temperature ~80 oC through the molar ratio 1:10 (M2+: thiourea) in aqueous media. Infrared spectra, XRD, TEM including EDX, and elemental analysis were used for characterization the metal sulfides products. The average crystalline size of obtained CdS and NiS particles in range 20-25 nm. Different reaction conditions effects were evaluated on the size, morphology and particle size. \u0000 \u0000KEY WORDS: Nickel and cadmium sulfide, Chelation, Thiourea, XRD, TEM \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 663-674. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.10 \u0000 ","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49422882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Zinc leaching from smithsonite ore in lactic acid solution: Studies on parametric optimization, kinetic and mechanism 乳酸溶液中史密斯矿浸出锌的参数优化、动力学及机理研究

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.15

Sıla Sadiye Ilhan, F. Demir, Omer Lacin, Fatih Sevim

{"title":"Zinc leaching from smithsonite ore in lactic acid solution: Studies on parametric optimization, kinetic and mechanism","authors":"Sıla Sadiye Ilhan, F. Demir, Omer Lacin, Fatih Sevim","doi":"10.4314/bcse.v37i3.15","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.15","url":null,"abstract":"ABSTRACT. The solubility of low-grade zinc ores with a selective leaching environmentally friendly reagent has become a focus of great interest since zinc and its compounds have found wide application. For this purpose, lactic acid was used to investigate the selective leaching kinetics of smithsonite ore obtained from Kayseri region. The effects of particle size (137.5-725 µm), acid concentration (0.5-5 M), solid/liquid ratio (0.5/250-3/250 g mL-1), stirring speed (500-800 rpm) and temperature (40-70 °C) parameters on the smithsonite dissolution rate were experimentally studied. The results obtained show that leaching of about 99.8% of zinc is achieved using 425 µm particle size at a reaction temperature of 70 °C for 45 min reaction time with 2 M lactic acid, the solid/liquid ratio of 1/250 g mL-1 and stirring speed of 600 rpm. The statistical analysis of the experimental data obtained from the parameters revealed that smithsonite dissolution was the surface reaction-controlled with an apparent activation energy of 53.62 kJ.moL-1. The kinetic model describing the process was found as \u0000 \u0000KEY WORDS: Smithsonite, Dissolution kinetics, Lactic acid, Zinc lactate \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 735-744. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.15","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46169807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physicochemical properties and microbial load evaluation of raw cow milks of Jimma Town, Ethiopia 埃塞俄比亚Jimma镇生牛奶的理化性质和微生物负荷评价

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.2

Tesfaye Tadesse, A. Gure, K. Kedir

{"title":"Physicochemical properties and microbial load evaluation of raw cow milks of Jimma Town, Ethiopia","authors":"Tesfaye Tadesse, A. Gure, K. Kedir","doi":"10.4314/bcse.v37i3.2","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.2","url":null,"abstract":"ABSTRACT. In this study, physicochemical properties and microbial loads of raw and sterilized cow milks of Jimma town, Ethiopia, were investigated. Raw and sterilized milk samples were collected from milk venders and local market, respectively. Standard methods were used for analysis of both physicochemical and microbial loads of the samples. The results of the study showed that physicochemical properties of the studied milk samples were within the recommended values. The total bacteria count (TBC) and coliform count (CC) of raw milk samples were above the recommended values, whereas their values in the sterilized milk sample were comparable with the recommended values. However, the yeast and mould count (YMC) of the studied milk samples were comparable with their recommended values. ANOVA (p < 0.05) results showed the presence of significant differences in the physicochemical properties such as temperature, pH, titratable acidity, total solids, solids not fat, protein, fat, lactose, total bacteria count and coliform count among the studied milk samples. In general, the studied raw and sterilized milk samples had acceptable physicochemical properties. However, the TBC and CC of the raw milk samples were above their respective recommended values, which might be attributed to the low hygienic practices of the venders. \u0000 \u0000KEYWORDS: Raw and sterilized cow milks, Physicochemical properties, Microbial load \u0000 \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 553-563. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.2","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44123975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the effect of some polar organic solvents on the leaching and dissolution kinetics of chalcopyrite in hydrogen peroxide and sulfuric acid solution 几种极性有机溶剂对黄铜矿在过氧化氢和硫酸溶液中浸出和溶解动力学影响的研究

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.19

Mohamed Taha Osman Abdelraheem, T. Agacayak

{"title":"Investigation of the effect of some polar organic solvents on the leaching and dissolution kinetics of chalcopyrite in hydrogen peroxide and sulfuric acid solution","authors":"Mohamed Taha Osman Abdelraheem, T. Agacayak","doi":"10.4314/bcse.v37i3.19","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.19","url":null,"abstract":"ABSTRACT. The effect of acetic acid and ethanol as polar aqueous solvents on sulfuric acid with hydrogen peroxide as an oxidant was studied. A small amount of these polar aqueous solvents significantly improved the copper leaching recovery. The leaching parameters such as temperature, stirring speed, H2O2 concentration, solid/liquid ratio, H2SO4 concentration and particle size were examined. About 76.33% as highest Cu extraction was gained with 2 M H2O2, 600 rpm stirring speed, 50 °C temperature, 1 M H2SO4, 240 min of the reaction and 75 x 53 µm particle size fraction. Further experimental tests were carried out when the stirring speed, solid-to-liquid ratio (S/L), particle size, H2O2 concentration, temperature and H2SO4 concentration were kept constant to investigate the effect of ethanol and acetic acid concentration in the range of 0–2 M. The experimental results proved that the copper extraction recovery reached to 99.03% in 180 min of the reaction with 2 M acetic acid. While 2 M of ethanol increased copper extraction recovery up to 100% in 90 min of the leaching time. The dissolution reaction found to be described by mixed kinetic model and activation energy of 54.37 kJ/mol. Addition of acetic acid and ethanol suggested reaction controlled by diffusion across product layer. \u0000 \u0000KEY WORDS: Hydrogen peroxide, Sulfuric acid, Activation energy, Leaching, Chalcopyrite \u0000 \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 779-788. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.19","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47390328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Structure and properties of strontium phosphate glasses modified with aluminum oxide applied as glass ionomer cement 应用于玻璃离子水泥的氧化铝改性磷酸锶玻璃的结构与性能

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.9

G. El-Damrawi, D. Shosha, A. M. Abdelghany, M. I. Abdelghany

引用次数: 0

Adsorption of diazo dye direct red-28 and tetra-azo dye direct black-22 using calcined kaolin in aqueous solutions 煅烧高岭土在水溶液中吸附重偶氮染料直接红-28和四偶氮染料直接黑-22

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.5

S. Fındık

{"title":"Adsorption of diazo dye direct red-28 and tetra-azo dye direct black-22 using calcined kaolin in aqueous solutions","authors":"S. Fındık","doi":"10.4314/bcse.v37i3.5","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.5","url":null,"abstract":"ABSTRACT. In this study, the removal of diazo and tetra-azo dyes using calcined kaolin were compared. Direct red-28 (DR-28) and Direct black-22 (DB-22) was chosen as diazo and tetra-azo dyes, respectively. The kaolin obtained from Turkiye and calcined at 200 °C was found to be the most efficient adsorbent. Natural and calcined kaolins were characterized using SEM-EDS, FTIR, TGA, and XRD. The parameters such as, calcination temperature of the kaolin, adsorbent amount, temperature, initial pH, contact time, and initial concentration were studied. It was found that the removal rate of DR-28 was higher than that of DB-22 at the studied conditions. The removal of DR-28 and DB-22 were found to be 90.1% and 46.2% under the following conditions: adsorbent amount: 1.2 g/200 mL, initial concentration: 20 mg/L, original pH, temperature: 20 °C and contact time 120 min. The adsorption of the dyes was fitted to Langmuir isotherm model. The maximum adsorption capacity of calcined kaolin at 200 °C was determined as 5.39 and 3.5 mg/g for DR-28 and DB-22, respectively. The adsorption of DR-28 and DB-22 followed a pseudo-second order model. The thermodynamic study showed that the adsorption of DB-22 onto calcined kaolin was endothermic while that of DR-28 was exothermic. \u0000 \u0000KEY WORDS: Adsorption, Diazo dye, Tetra-azo dye, Kaolin \u0000 \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 593-610. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.5","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43895036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Zinc(II) complex of (Z)-4-((4-nitrophenyl)amino)pent-3-en-2-one, a potential antimicrobial agent: synthesis, characterization, antimicrobial screening, DFT calculation and docking study 潜在抗菌剂（Z）-4-（（4-硝基苯基）氨基）戊-3-烯-2-酮锌（II）配合物的合成、表征、抗菌筛选、DFT计算和对接研究

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.8

I. Waziri, O. O. Wahab, G. A. Mala, S. O. Oselusi, S. A. Egieyeh, H. Nasir

{"title":"Zinc(II) complex of (Z)-4-((4-nitrophenyl)amino)pent-3-en-2-one, a potential antimicrobial agent: synthesis, characterization, antimicrobial screening, DFT calculation and docking study","authors":"I. Waziri, O. O. Wahab, G. A. Mala, S. O. Oselusi, S. A. Egieyeh, H. Nasir","doi":"10.4314/bcse.v37i3.8","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.8","url":null,"abstract":"ABSTRACT. Herein, the synthesis and characterizations of (Z)-4-((4-nitrophenyl)amino)pent-3-en-2-one (HL) ligand and its Zn(II) complex are reported. The compounds were characterized using elemental and thermogravimetric (TGA) analysis, electrochemical studies, FTIR, UV-Vis, 1H and 13C{H}NMR, HRMS, and PXRD techniques. Antimicrobial activity was screened on some Gram-positive and Gram-negative bacteria. DFT predictions were achieved using B3LYP, ωB97XD and M06-2X functional with 6-31+G(d,p) and LANL2DZ basis sets for nonmetallic and metallic atoms, respectively. The therapeutic potentials of the compounds were evaluated based on protein binding affinity, ADME/T and drug-likeness properties. The experimental results revealed the formation of a complex in which two ligands coordinated to the zinc ion in a tetrahedral arrangement through their carbonyl and amino groups. The antimicrobial study showed that the complex possesses higher antimicrobial activity than free ligand and the control (Streptomycin). B3LYP emerged as the best performing functional having yielded the best IR spectra and geometrical parameters relative to the experimental data. The density functional theory (DFT) predictions revealed that the complex is more active than the ligand, and its formation is thermodynamically feasible and exothermic. The docking results revealed that the binding affinities of the compounds are in agreement with the in-vitro data, and they possess drug-like properties. \u0000 \u0000KEY WORDS: Schiff base, Zinc complex, Antimicrobial, DFT, Docking study \u0000 \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 633-651. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.8","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48952469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

p-Anisidine release study by hydrolysis of Schiff bases in homogeneous media 均匀介质中席夫碱水解对茴香胺释放研究

IF 1.2 4区化学

Bulletin of the Chemical Society of Ethiopia Pub Date : 2023-03-06 DOI: 10.4314/bcse.v37i3.16

Awatif Amaria Moulay, Kheira Diaf, Zineb Elbahri, Abderrezzak Mesli, N. Chafi, N. Besbes

{"title":"p-Anisidine release study by hydrolysis of Schiff bases in homogeneous media","authors":"Awatif Amaria Moulay, Kheira Diaf, Zineb Elbahri, Abderrezzak Mesli, N. Chafi, N. Besbes","doi":"10.4314/bcse.v37i3.16","DOIUrl":"https://doi.org/10.4314/bcse.v37i3.16","url":null,"abstract":"ABSTRACT. The objective of this work is to study the release of p-anisidine by the hydrolysis of synthesized Schiff bases N-vinylbenzylidene-p-anisidine (Im) as a monomer and its copolymers (Cp1, Cp2) with N,N-dimethylacrylamide (DMA). The hydrolysis behavior and kinetics are investigated in homogeneous media composed of ethanol/water (80% v/v) at 37 °C and at pH range of 4.0-10.0. The variation of the concentration over time is measured in thermostatically cells using UV-Vis spectroscopy. The results showed that the imine function hydrolysis obeyed to the first order for all compounds; the experimental kinetic constants are determined and the pH–rate diagram profile is established. It is noticed that the hydrolysis of imine function is extremely dependent on its carrier and the pH medium. \u0000 \u0000KEY WORDS: p-Anisidine, Copolymer, Schiff base, Hydrolysis, pH–rate diagram, Controlled release \u0000 \u0000Bull. Chem. Soc. Ethiop. 2023, 37(3), 745-755. \u0000DOI: https://dx.doi.org/10.4314/bcse.v37i3.16 ","PeriodicalId":9501,"journal":{"name":"Bulletin of the Chemical Society of Ethiopia","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48391491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0