Cardiovascular Intervention and Therapeutics最新文献

{"title":"Effective management of pinhole rupture in stent mount balloon during percutaneous coronary intervention.","authors":"Hirohiko Ando, Kento Kawaguchi, Tomohiro Onishi, Reiji Goto, Akihiro Suzuki, Tetsuya Amano","doi":"10.1007/s12928-025-01187-6","DOIUrl":"https://doi.org/10.1007/s12928-025-01187-6","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful two-stage revascularization by securing a temporary distal outflow via an arteriovenous fistula for a long-segment infrainguinal arterial occlusion.","authors":"Tetsuya Nomura, Mai Imanaka, Shuhei Ogawa, Hiroshi Kubota, Yukinori Kato, Naotoshi Wada","doi":"10.1007/s12928-025-01189-4","DOIUrl":"https://doi.org/10.1007/s12928-025-01189-4","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes after percutaneous coronary intervention or coronary artery bypass grafting in patient with left main coronary artery disease: the TOkai LEft main RevAscularizatioN sTrategy (TOLERANT) study.","authors":"Thitima Limjaroen, Yoshihisa Kinoshita, Yuki Suzuka, Yoshihiro Goto, Jyunji Yanagisawa, Yoriyasu Suzuki, Hideki Kitamura, Munenori Okubo, Yoshiaki Kawase, Hitoshi Matsuo, Yutaka Koyama, Yasuhide Okawa, Takahiko Suzuki","doi":"10.1007/s12928-025-01185-8","DOIUrl":"https://doi.org/10.1007/s12928-025-01185-8","url":null,"abstract":"<p><p>The outcome of percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) is still controversial for patients with left main coronary artery (LMCA) disease. This multicenter cohort study aimed to evaluate the clinical outcomes of LMCA disease patients who underwent PCI or CABG. We reviewed 875 consecutive patients diagnosed with LMCA disease between January 2009 and December 2020 who underwent coronary revascularization by PCI (n = 404) or CABG (n = 471). A one-to-one propensity score matching was employed to control the potential biases. The primary outcome was any major adverse cardiac events (MACE), which were composed of all causes of death, myocardial infarction, or stroke. Before propensity score matching, both groups significantly differed in essential baseline characteristics. Patients undergoing PCI were significantly older (age 72.4 vs. 70.5 years). They had a better baseline left ventricular function (left ventricular ejection fraction (LVEF) 59.1% vs. 55.8%). Moreover, patients in the PCI group had less coronary artery disease burden, such as less frequency of SYNTAX scores ≥ 33 (25.1% vs. 49.0%) and true left main bifurcation disease (18.6% vs. 33.1%). After propensity score analysis, 191 pairs of patients were successfully matched, and the median follow-up time was 4.5 years. A primary outcome event occurred in 8.9% of the patients in the PCI group and 15.2% in the CABG group (HR 0.70; 95% confidence interval [CI] 0.38-1.28; P = 0.253). All causes of death were lower in the PCI group than in the CABG group (8.4% vs. 13.6%; P = 0.347), but the difference was insignificant. In PCI and CABG groups, the incidence of cardiovascular death (1.6% vs. 1.1%), myocardial infarction (1.1% vs. 1.1%), and stroke (0% vs. 1.6%) were also not significantly different. However, the incidence of any revascularization and hospitalization for heart failure tended to be higher in the PCI group than in the CABG group, but the difference was not significant. In this propensity-matched study, PCI showed a statistically insignificant difference in all causes of death, myocardial infarction, or stroke compared with CABG for the treatment of LMCA disease. Furthermore, PCI showed no statistically significant difference compared to CABG in overall endpoints, including any revascularization.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stent thrombosis in acute myocardial infarction in the era of second-generation drug-eluting stent: incidence, prognosis, and historical comparisons with previous stent era.","authors":"Yosuke Kirii, Tairo Kurita, Hiroki Kainuma, Kazuma Yamaguchi, Hiroki Mori, Masashi Yanagisawa, Takahiro Okazaki, Akiyoshi Ikami, Tomoyuki Fukuma, Hiromasa Ito, Takashi Kato, Masaki Ishiyama, Akihiro Takasaki, Yuichi Sato, Takeshi Takamura, Kaoru Dohi","doi":"10.1007/s12928-025-01186-7","DOIUrl":"https://doi.org/10.1007/s12928-025-01186-7","url":null,"abstract":"<p><strong>Background: </strong>Stent thrombosis (ST) remains a serious complication after percutaneous coronary intervention, leading to acute myocardial infarction (AMI) in over 70% of cases. And it has been reported that the prognosis for ST is worse than for de-novo AMI. While the use of second-generation drug-eluting stents (G2-DES) has reduced ST incidence, ST remains a concern, and its incidence and prognosis in the G2-DES era have not been well studied.</p><p><strong>Aims: </strong>To evaluate the incidence and prognosis of AMI due to ST in the G2-DES era compared with de-novo AMI.</p><p><strong>Methods: </strong>From January 2013 to November 2022, we analyzed 6273 consecutive AMI patients from the Mie ACS Registry, including 78 ST and 6195 de-novo type 1 AMI (de-novo AMI) after exclusion of the other type of AMI. The primary endpoint was all-cause mortality, and target lesion revascularization (TLR) was the secondary endpoint.</p><p><strong>Results: </strong>ST occurred in 1.2% (n = 78) of AMI, predominantly as very late ST (79.5%, n = 62). Thirty-day mortality was marginally lower in ST (2.6%) than de-novo AMI (6.7%, p = 0.16), with ST not being an independent predictor of 30-day mortality (HR 0.39, p = 0.19). However, ST patients had a higher 2-year TLR rate (21.4% vs. 11.9%, p = 0.02), confirmed as an independent predictor (HR 2.03, p = 0.01). Compared to previous clinical data, the reduced incidence of ST and the improved prognosis was observed.</p><p><strong>Conclusions: </strong>While ST-related AMI prognosis has improved, with mortality comparable to de-novo AMI, the higher TLR rate in ST patients persists, and an optimized revascularization strategy is still needed.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of procedural efficiency between transradial and transfemoral access in iliac artery EVT: a retrospective study.","authors":"Tomohide Endo, Kazumasa Saito, Shuntaro Sakai, Daisuke Horiuchi, Hiromitsu Matsui","doi":"10.1007/s12928-025-01182-x","DOIUrl":"https://doi.org/10.1007/s12928-025-01182-x","url":null,"abstract":"<p><p>Transradial access (TRA) is increasingly used in endovascular therapy (EVT) due to its favorable safety profile. However, its procedural efficiency compared to transfemoral access (TFA) remains under investigation. We retrospectively analyzed 132 consecutive EVT procedures for iliac artery lesions performed between April 2020 and March 2024. After excluding 11 dialysis-dependent and 3 urgent cases, 118 elective cases were included (TRA: 65; TFA: 53). Four procedural time intervals were assessed: (1) room entry to local anesthesia, (2) local anesthesia to sheath removal, (3) sheath removal to room exit, and (4) total room time. In the primary analysis, 45 matched pairs were created using propensity score matching based on five covariates: chronic total occlusion (CTO), bilateral calcification, TASC C/D lesions, stent occlusion, and covered stent use. A secondary analysis was performed in 19 matched CTO cases using three covariates. In the matched cohort, TRA demonstrated significantly shorter total room time compared to TFA (75 [60-115] vs. 105 [74-163] min, p = 0.003). Sheath removal to room exit time was also consistently shorter in the TRA group (7 [5-10] vs. 14 [12-17] min, p < 0.001). Similar findings were observed in the CTO-matched subgroup (93 [77-163] vs. 160 [110-220] min, p = 0.012). TRA significantly reduces procedural time compared to TFA in iliac artery EVT. The consistent reduction across all phases, including the post-procedural period, highlights TRA as an efficient and practical access strategy in peripheral vascular interventions.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When size matters: successful transcatheter closure of an extra-large PFO using an ASD occluder.","authors":"Ryotaro Maeda, Takeshi Nakamura, Michiyo Yamano, Tetsuhiro Yamano, Kan Zen, Satoaki Matoba","doi":"10.1007/s12928-025-01184-9","DOIUrl":"https://doi.org/10.1007/s12928-025-01184-9","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic phenotypes of severe aortic stenosis in patients with small aortic annulus and implications for transcatheter aortic valve implantation outcomes.","authors":"Lorenzo Niro, Chiara Pidone, Elena Ferrer-Sistach, Albert Teis, Victoria Vilalta, Eduard Fernández-Nofrerias, Xavier Carrillo, Antoni Bayes-Genís, Victoria Delgado","doi":"10.1007/s12928-025-01180-z","DOIUrl":"https://doi.org/10.1007/s12928-025-01180-z","url":null,"abstract":"<p><p>Patients with severe aortic stenosis (AS) and small aortic annulus pose diagnostic and therapeutic challenges. To investigate the frequency of discordant grading of severe AS in patients with a small aortic annulus and to evaluate the outcomes after transcatheter aortic valve implantation (TAVI). Patients with severe AS, an aortic annulus diameter of < 21 mm on echocardiography, a mean annulus diameter of < 23 mm, and an area ≤ 4.3 cm² on cardiac computed tomography, who underwent TAVI, were retrospectively analyzed. The frequency of low-gradient severe AS was assessed. Patients were followed up for the occurrence of the composite endpoint of all-cause mortality, rehospitalizations for heart failure, non-fatal myocardial infarction, and non-fatal stroke. Among 230 patients with severe AS and a small aortic annulus (age 82 ± 6 years, 85% female), 52 (23%) had low gradient, while 120 (52%) exhibited normal flow-high gradient and 58 (25%) had low flow-high gradient. During a median follow-up of 2 years, the composite endpoint occurred in 29% of the total cohort. Patients with low-gradient severe AS experienced the worse outcome (HR = 2.46; 95% CI: 1.13-5.33; p = 0.023). Almost one-fourth of patients with severe AS and small annulus have low gradient AS. These patients experienced worse outcomes, likely reflecting advanced myocardial remodeling due to delayed referral and the diagnostic challenges posed by small annular dimensions.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closure of left atrial appendage following incomplete surgical ligation using an Amplatzer^™ Septal Occluder.","authors":"Pierre Rossignon, Thomas De Beenhouwer, Michael Rietz, Panagiotis Xaplanteris, Ivan Dimov, Quentin de Hemptinne","doi":"10.1007/s12928-025-01181-y","DOIUrl":"https://doi.org/10.1007/s12928-025-01181-y","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first in-silico simulation of Evolut-in-Evolut TAVR: reproduction of a real clinical scenario.","authors":"Benedetta Grossi, Ottavia Cozzi, Giulia Luraghi, Damiano Regazzoli, Francesco Migliavacca, Giulio Stefanini","doi":"10.1007/s12928-025-01183-w","DOIUrl":"https://doi.org/10.1007/s12928-025-01183-w","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-density lipoprotein cholesterol to apolipoprotein B ratio as a predictor of clinical outcomes following percutaneous coronary intervention: a propensity score-matched analysis.","authors":"Masaki Matsuzaki, Takashi Kuwano, Riku Tsudome, Takashi Maruo, Yuto Kawahira, Eiji Shigemoto, Makoto Sugihara, Shin-Ichiro Miura","doi":"10.1007/s12928-025-01178-7","DOIUrl":"https://doi.org/10.1007/s12928-025-01178-7","url":null,"abstract":"<p><p>Residual cardiovascular risk after percutaneous coronary intervention (PCI) remains a concern despite optimal low-density lipoprotein cholesterol (LDL-C) management. The LDL-C/apolipoprotein B (ApoB) ratio is a potential marker for LDL particle size and atherogenicity. This study investigated the prognostic value of the pre-treatment LDL-C/ApoB ratio for major adverse cardiac events (MACE) in patients with coronary artery disease who underwent PCI. Among 2116 consecutive patients enrolled between 2015 and 2022 in the Fukuoka University PCI prospective registry, this study analyzed 1682 individuals who were divided into two groups according to their LDL-C/ApoB ratio (< 1.2 vs. ≥ 1.2). The primary outcome was 3-year MACE. After propensity score matching (315 pairs), the low LDL-C/ApoB ratio (< 1.2) was associated with higher MACE (Adjusted HR 1.50, 95% CI 1.04-2.16, p = 0.030). Restricted cubic spline analysis in the matched cohort revealed a significant continuous inverse association between the LDL-C/ApoB ratio and MACE risk. Notably, this predictive value persisted even after propensity score matching balanced for triglyceride-rich lipoprotein-related markers (triglycerides, remnant-like particle cholesterol) and HDL-C. The pre-treatment LDL-C/ApoB ratio is an independent predictor of MACE after PCI, demonstrating a continuous inverse relationship with risk, even when accounting for other atherogenic lipoproteins. This easily calculable ratio may enhance risk stratification by identifying residual risk associated with LDL particle characteristics.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}