Cardiovascular Journal of Africa最新文献

{"title":"Evaluation of six-month clinical outcomes of patients with venous thromboembolism treated with apixaban, rivaroxaban, edoxaban or dabigatran.","authors":"Abdulkadir Yilmaz, Dogan Emre Sert, Sinan Sabit Kocabeyoglu, Emrah Uguz, Enis Burak Gül, Bekir Boğaçhan Akkaya, Umit Kervan, Zeki Catav","doi":"10.5830/CVJA-2026-015","DOIUrl":"10.5830/CVJA-2026-015","url":null,"abstract":"<p><strong>Background: </strong>The advantages of direct oral anticoagulants (apixaban, rivaroxaban, edoxaban, dabigatran) over warfarin and low molecular weight heparin have been demonstrated in many studies in the treatment of patients with acute venous thromboembolism (VTE). However, a single-centre study comparing the effectiveness and safety of oral anticoagulants against each other has not yet been conducted.</p><p><strong>Aim: </strong>The study aimed to compare the results of the efficacy and safety profiles of direct oral anticoagulants (DOACs). The purpose of this study was to compare the effectiveness and safety profiles of DOACs.</p><p><strong>Methods: </strong>The study included 192 patients diagnosed with VTE in Ankara City Hospital between 2019 and 2022. Patients diagnosed with deep vein thrombosis by venous doppler ultrasonography and those diagnosed with pulmonary embolism by pulmonary computed tomography angiography (CTA) were included in the study. The patients who received regular treatment for six months and came to their controls regularly were analysed. During the six months, control venous doppler ultrasonography or pulmonary CTA was performed in all patients with symptoms or examination findings suspicious of VTE. Relevant blood values of patients with hepatic or renal dysfunction were observed at the beginning of the treatment. The primary endpoints were recurrent VTE, mortality, and major bleeding events.</p><p><strong>Results: </strong>The 192 patients included in the study were divided into four groups, with at least 45 patients in each drug group. There was no significant difference between the groups regarding gender, age, weight, comorbidity, rate of provoked VTE, and kidney and liver function tests. 90.6% of the patients had isolated deep venous thrombosis. There was a provoking reason in 49.5%. Obesity and immobilisation were the most frequent provoking causes. During the six-month treatment period, recurrent VTE was observed in three patients, major bleeding in two patients, and death in four patients. Non-major bleeding was seen in 40 patients. There was no significant difference between the four drug groups regarding efficacy and safety.</p><p><strong>Conclusion: </strong>Our study is essential in comparing the efficacy and safety of four direct oral anticoagulant drugs. Our findings supported that dabigatran, apixaban, edoxaban, and rivaroxaban treatments can be used safely and effectively in the treatment of acute VTE. While high efficacy was achieved with all drugs, a low rate of side effects was observed.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 3","pages":"253-258"},"PeriodicalIF":0.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between serum uric acid-to-high-density lipoprotein cholesterol ratio and myocardial bridging: a cross-sectional study.","authors":"Emirhan Hancıoğlu, Sevgi Özcan, Özkan Bekler, Asım Enhoş, Ertuğrul Okuyan","doi":"10.5830/CVJA-2026-012","DOIUrl":"https://doi.org/10.5830/CVJA-2026-012","url":null,"abstract":"<p><strong>Background: </strong>Myocardial bridging (MB) is a congenital coronary anomaly that is often regarded as a benign condition but may lead to adverse clinical outcomes. Systemic metabolic and inflammatory markers have been suggested as potential indicators of MB.</p><p><strong>Objective: </strong>To investigate the association between the uric Acid-to-high-density lipoprotein cholesterol ratio (UHR) and the presence of MB.</p><p><strong>Methods: </strong>In this retrospective study, patients who underwent elective coronary angiography were evaluated. A total of 245 patients meeting the inclusion criteria were included. Based on angiographic findings, patients were classified into two groups: those with MB (MB[+]) and a control group with normal coronary arteries. Serum UHR, neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-HDL cholesterol ratio (MHR) were calculated. Univariate and multivariate logistic regression analyses were performed to determine independent predictors of MB. Receiver operating characteristic (ROC) curve analysis was used to evaluate the discriminative performance of inflammatory indices.</p><p><strong>Results: </strong>Among the 245 patients included in the study, 129 (52.6%) had MB. In multivariate analysis, NLR (odds ratio [OR] = 2.858, 95% confidence interval [CI]: 1.750-4.668, p = 0.001), MHR (OR = 1.126, 95% CI: 1.021-1.242, p = 0.018), and UHR (OR = 1.342, 95% CI: 1.161-1.552, p = 0.001) were independent predictors of MB. ROC analysis demonstrated that UHR had the highest discriminative ability for MB (AUC = 0.853, 95% CI: 0.803-0.902, p < 0.001), with an optimal cut-off value of 9.9, yielding 81.4% sensitivity and 80.3% specificity.</p><p><strong>Conclusion: </strong>UHR is an independent predictor of MB and may serve as a useful biomarker for guiding clinical management.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 3","pages":"264-268"},"PeriodicalIF":0.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148419084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-operative MELD-Na score as an independent predictor of post-operative mortality after valve surgery in rheumatic valvular heart disease patients.","authors":"Lidetu K Kayamo, Yonas A Teferi, Arega F Leta","doi":"10.5830/CVJA-2026-016","DOIUrl":"https://doi.org/10.5830/CVJA-2026-016","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Rheumatic heart disease (RHD) poses a significant global health challenge due to its high rates of premature morbidity, mortality, and disability, particularly in low-income countries. Existing risk scoring systems for valve replacement in cardiac surgery have primarily focused on non-RHD cases, making them less applicable to RHD patients due to the distinct pathology of valvular damage. This study aims to evaluate the Model for End-stage Liver Disease, including sodium (MELD-Na) score, as a predictive tool for pre-operative mortality risk assessment following cardiac surgery in RHD patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective cohort study was conducted at Tenwek Hospital in Kenya and included 93 patients who underwent open heart valve replacement surgery between March 2022 and March 2023. Patients who underwent mechanical mitral valve replacement (MVR), mechanical aortic valve replacement (AVR), and tricuspid valve repair surgery (TVr) were included. Data were collected from Tenwek Hospital's electronic medical record system, and statistical analysis was performed using IBM SPSS Statistics 27.0, including Chi-square and binary logistic regression. Operative mortality was defined as all deaths occurring during the hospitalisation period of the operation and within 30 days post-discharge, unless unrelated to the procedure.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study included a cohort of 93 patients, comprising 36 (38.7%) males and 57 (61.3%) females, with a median age of 25. The majority of patients presented with mitral valve disease, 63 (67.7%), with varying degrees of mitral regurgitation, 32 (34.4%) and mitral stenosis, 31 (33.3%). Notably, 43 (46.2%) of patients exhibited an elevated MELD-Na score falling within the range of 9-15, while 20 (21.5%) had severely elevated scores exceeding 15. The overall mortality rate was 10 (10.8%), with a majority, six (60%), of deaths occurring in patients with severely elevated MELD-Na scores and the remaining 40% in the moderate category. Logistic regression analysis was employed to compare the predictive value of MELD-Na score with EuroScore II as a baseline indicator. Subsequently, the analysis was repeated, incorporating individual components of the MELD-Na score. The results indicated a significant link between the MELD-Na score and operative mortality (p = 0.003), showing an odds ratio (OR) of 1.17 (95% confidence interval (CI): 1.05-1.30). Additionally, both serum creatinine (p = 0.012, OR: 1.04, 95% CI: 1.02-1.09) and the international normalised ratio (INR) (p = 0.005, OR: 2.8, 95% CI: 1.38-6.0) emerged as notable predictors of operative mortality.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Elevated MELD-Na scores are associated with an increased risk of operative mortality following RHD valve surgery, suggesting potential utility as a pre-operative risk stratification tool. Our findings underscore the utility of the MELD-Na score, particularly its components s","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 3","pages":"245-252"},"PeriodicalIF":0.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient education in cardiovascular disease in Sub-Saharan Africa: the \"Heart School\" pilot project at IPMS/Cheikh Anta Diop University of Dakar, Senegal.","authors":"Ngoné Diaba Gaye, Aliou Alassane Ngaïdé, Fatou Aw, Mame Madjiguène Ka, Cheikh Tidiane Tall, Abdoul Kane","doi":"10.5830/CVJA-2026-013","DOIUrl":"10.5830/CVJA-2026-013","url":null,"abstract":"<p><strong>Objective: </strong>To describe a patient education (PE) pilot project named \"theHeart School\" at Cheikh Anta Diop University of Dakar.</p><p><strong>Methods: </strong>This cross-sectional study included all patients referred to a PE program. PE was delivered in weekly one-onone sessions. Progression was assessed through self-evaluation scales with scores ranging from 0 to 10, administered before and after the program. Data analysis was performed with SPSS version 18 with a significance level of p < 0.05.</p><p><strong>Results: </strong>45 patients benefited from this educational program. Coronary artery disease (CAD) was the primary indication in 87% of cases. At the end of the program, there was a significant improvement in knowledge of the disease (4.5 vs. 7.4; p < 0.001) and its treatment (4.7 vs. 6.8; p < 0.001), as well as good practices of physical activity (4.5 vs. 7; p < 0.001), cardioprotective diet (4.2 vs. 7; p < 0.001) and motivation to change lifestyle (5.6 vs. 7.8; p < 0.001).</p><p><strong>Conclusion: </strong>Results from this pilot project were promising. However, long-term follow-up is necessary to better assess the sustainability of these results.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 3","pages":"259-263"},"PeriodicalIF":0.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes and haemodynamic evolution following Perceval sutureless aortic valve implantation in high-risk aortic stenosis patients.","authors":"Emced Khalil","doi":"10.5830/CVJA-2026-020","DOIUrl":"https://doi.org/10.5830/CVJA-2026-020","url":null,"abstract":"<p><strong>Background: </strong>Sutureless aortic valve replacement (AVR) has been recognised as a potential option in the management of High-risk patients, characterised by reduced procedural times and satisfactory haemodynamic results. However, mid-term results of valve-related outcomes are scarce. This study aimed to investigate clinical, echocardiographic, and valve-related outcomes of high-risk patients undergoing Perceval sutureless AVR.</p><p><strong>Methods: </strong>The current retrospective, single-centre study included 50 consecutive high-risk patients who had isolated Perceval sutureless AVR. The time period was between January 2023 and December 2024. The primary endpoint was one-year valve-related survival. The secondary endpoints included echocardiographic performance, paravalvular leakage (PVL), patient-prosthesis mismatch (PPM), and the need for pacemaker implantation. Transthoracic echocardiography was performed at discharge and follow-up.</p><p><strong>Results: </strong>Complete echocardiographic follow-up at 12 months was available for 44 patients (88%). The transvalvular gradient significantly decreased from 46.8 ± 11.2 to 12.4 ± 3.6 at discharge and remained stable at 12 months (12.1 ± 3.5; p < 0.001). The indexed effective orifice area increased from 0.58 ± 0.09 to 1.10 ± 0.16 cm²/m² at 12 months. No case of severe patient-prosthesis mismatch (PPM) was noted, but moderate PPM occurred in 12%. PVL was trivial or mild in all patients. Permanent pacemaker implantation was necessary in 20%, all within the index hospitalisation period, without any recovery of native conduction at follow-up. Valve-related survival at 12 months was 94%, with death from non-valve-related causes.</p><p><strong>Conclusion: </strong>Sutureless Perceval aortic valve implantation has been shown to provide excellent clinical and haemodynamic results at midterm follow-up in high-risk patients with low rates of valve-related complications, PVL, and patient prosthesis mismatch.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 3","pages":"269-274"},"PeriodicalIF":0.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of dobutamine stress echocardiography: A South African experience.","authors":"André P Dippenaar, Lariska Scherman, Amanda Espach, Anja De Lange, Louiso du Pisanie, Brandon Franckeiss, Paul A Brink, Pieter van der Bijl","doi":"10.5830/CVJA-2025-115","DOIUrl":"https://doi.org/10.5830/CVJA-2025-115","url":null,"abstract":"<p><strong>Background: </strong>Dobutamine stress echocardiography (DSE) is a well-established modality for the diagnosis and risk-stratification of coronary artery disease, but no prognostic data have been reported from Southern Africa.</p><p><strong>Objectives: </strong>We investigated the prognostic utility of a South African DSE programme and compared the results to larger, internationals series.</p><p><strong>Methods: </strong>All patients under going DSE from 2019 to 2023 at a single South African centre were included. A new wall motion abnormality (≥ 2 segments) signified inducible ischaemia.</p><p><strong>Results: </strong>166 patients (median age 65 ± 11years, 69% male) were analysed. 52 patients (31%) had diabetes mellitus, 155 (93%) had dyslipidaemia and 35 (21%) were smokers. 48 (29%) patients had received previous percutaneous revascularization and 10 (6%) coronary artery bypass surgery. During a median follow-up of 36 ± 7 months, 33 (20%) patients died or underwent coronary artery revascularization. Individuals with demonstrable, inducible ischaemia, experienced a higher rate of all-cause mortality or revascularization during follow-up.</p><p><strong>Conclusion: </strong>The prognostic value of a South African DSE programme for all-cause mortality and revascularization was demonstrated for the first time. Data are aligned with large, international series with comparable follow-up time.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 2","pages":"229-233"},"PeriodicalIF":0.7,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between symptomatic lower extremity peripheral artery disease with carotid artery stenosis and ischemic stroke.","authors":"Hasan Hüseyin Kır, Mehmet Işık, Ömer Tanyeli, Mukaddes Ruveydagül Ceran, Ali Vasfi Ağlarcı, Muhammet Talha Ceran, Hasan Hüseyin Kozak","doi":"10.5830/CVJA-2026-001","DOIUrl":"https://doi.org/10.5830/CVJA-2026-001","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the prevalence of carotid artery stenosis (CAS) in peripheral artery disease (PAD) patients requiring surgical or interventional procedures, to examine the clinical relationship between CAS and PAD, and to determine the characteristics of ischemic stroke developing within a one-year postoperative period.</p><p><strong>Methods: </strong>Between August 2020 and January 2024, Doppler ultrasonography was performed to image the carotid arteries in patients diagnosed with PAD who underwent interventional procedures or surgical operations (Fontaine classification stage 2B and above). A total of 108 patients who continued follow-up were prospectively monitored for cerebrovascular events for 1 year.</p><p><strong>Results: </strong>A near-significant association was observed between claudication distance and history of stroke (p = 0.08). Another near-significant association was found between claudication distance and National Institutes of Health Stroke Scale (NIHS) scores in patients who had a stroke (p = 0.07). A positive correlation (p < 0.01) was found between a history of stroke with severe CAS and NIHS scores.</p><p><strong>Conclusions: </strong>In our study, we found that the prevalence of CAS was higher in PAD patients compared to the general population, and that they had a significant risk of cerebrovascular events during follow-up. Our study supports other studies recommending routine carotid ultrasound in patients diagnosed with PAD. The use of simple clinical measures such as claudication distance in cerebrovascular risk assessment may be beneficial in developing early diagnosis and treatment strategies in clinical practice.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 2","pages":"234-238"},"PeriodicalIF":0.7,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148326276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive efficiency of serum fibrinogen and D-Dimer levels for left ventricular remodelling after acute myocardial infarction.","authors":"Dong Li, Haiying Dong, Chengzhen Rong","doi":"10.5830/CVJA-2026-018","DOIUrl":"https://doi.org/10.5830/CVJA-2026-018","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to explore serum D-dimer plus fibrinogen (FIB) levels in acute myocardial infarction (AMI) for their efficiency in predicting subsequent left ventricular remodelling (LVRM).</p><p><strong>Methods: </strong>With the period between September 2021 and January 2023 selected, 112 AMI patients hospitalised for treatment were enrolled as the subjects that were allocated to either the non-LVRM group (n = 76) or the LVRM group (n = 36) based on the findings of echocardiography.</p><p><strong>Results: </strong>LVRM was found in 36 out of the 112 AMI patients, with an incidence rate of 32.14%, whereas the remaining 76 patients did not develop LVRM, accounting for 67.86%. The LVRM-related risk factors in AMI subjects included large infarction size, high D-dimer level, history of diabetes mellitus plus hypertension, infarction location (apex of left ventricle), and high FIB level (odds ratio > 1, p < 0.05). FIB and D-dimer levels had the areas under the plotted receiver operating characteristic curves for predicting LVRM in AMI patients of 0.764 and 0.875, respectively, showing high predictive values. FIB and D-dimer levels had a certain value in predicting LVRM in AMI patients within the threshold range of 0.04-0.95.</p><p><strong>Conclusion: </strong>The D-dimer and FIB level measurement for AMI sufferers is conducive to the prediction of LVRM incidence.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 2","pages":"239-244"},"PeriodicalIF":0.7,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: unilateral varicose veins.","authors":"Yu-Tzu Chien, Ping-Yi Lin","doi":"10.5830/CVJA-2026-010","DOIUrl":"https://doi.org/10.5830/CVJA-2026-010","url":null,"abstract":"<p><p>A healthy 69-year-old man presented to the cardiovascular surgery outpatient department with a 20-year history of right leg swelling and varicose veins (Figure A). He denied experiencing resting pain and had no bad habits such as smoking or alcohol consumption. His vital signs were normal. On physical examination, a palpable vein was noted with no redness, heat, or pain. Peripheral sonography revealed engorgement of the great saphenous vein. The laboratory results showed no significant findings except for a Para-Bombay blood group type A. Due to concerns about abdominal vessel disease, a computed tomography scan was performed, identifying an aneurysm in the abdominal aorta (Figure B) and common iliac artery? (Figure C), along with compression of the inferior vena cava and right common iliac vein.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 2","pages":"221-222"},"PeriodicalIF":0.7,"publicationDate":"2026-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity testing of the novel European Society of Cardiology EURObservational Research Programme PPCM Registry score to predict left ventricular recovery in a cohort of Ugandan women with PPCM.","authors":"Juliet Nabbaale, Karen Sliwa, Alice Jackson, Elena Libhaber, Emmy Okello, Annettee Nakimuli, Graham Chakafana","doi":"10.5830/CVJA-2025-099","DOIUrl":"10.5830/CVJA-2025-099","url":null,"abstract":"<p><strong>Background: </strong>Recently under the European Society of Cardiology (ESC) EURObservational Research Programme (EORP) PPCM registry the first predictive score was derived. This study sought to test the validity of this predictive score in a cohort of women with PPCM in Uganda.</p><p><strong>Methods: </strong>80 PPCM cases enrolled had a 12-lead electrocardiography, echocardiography at baseline and at 6-months follow-up. Core clinical data included LVEF, LVEDD, duration of symptoms, QRS duration and pre-eclampsia were captured.</p><p><strong>Results: </strong>Recovered participants' scores included one case who scored ≤ 1 and one of 2, six cases had a score of 3, fifteen cases had a score of 4, six cases had a score of 5, two cases had a score of 6 and only five cases had the highest score of 7. The discrimination analysis achieved a c-statistic of 0.67.</p><p><strong>Conclusion: </strong>The ESC EORP PPCM LV predictive recovery score under performed in predicting LV recovery in our Ugandan PPCM cohort.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"37 2","pages":"215-220"},"PeriodicalIF":0.7,"publicationDate":"2026-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148283387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}