CHEST pulmonaryPub Date : 2024-09-01DOI: 10.1016/j.chpulm.2024.100048
{"title":"Adapting the Tools of Our Trade","authors":"","doi":"10.1016/j.chpulm.2024.100048","DOIUrl":"10.1016/j.chpulm.2024.100048","url":null,"abstract":"","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S294978922400014X/pdfft?md5=1cc8501f0999a6eb9d2d64ca327addbb&pid=1-s2.0-S294978922400014X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-09-01DOI: 10.1016/j.chpulm.2024.100061
{"title":"Tackling Comprehensive Asthma Education for Providers One Breath at a Time","authors":"","doi":"10.1016/j.chpulm.2024.100061","DOIUrl":"10.1016/j.chpulm.2024.100061","url":null,"abstract":"<div><h3>Background</h3><p>Exponential growth of knowledge in asthma has advanced the diagnosis and treatment of personalized, phenotype- and endotype-driven care in asthma leading to improved clinical outcomes. However, many knowledge and practice gaps persist among health care professionals. Microlearning has demonstrated efficacy in educational outcomes but is often limited by fragmentation and incomplete information. To integrate the benefits of microlearning into a comprehensive asthma curriculum that addresses knowledge gaps in this rapidly growing field, we built an extensive curriculum in bite-sized, “one breath at a time” portions for physicians managing asthma.</p></div><div><h3>Research question</h3><p>Is creating an asthma curriculum online educational program with modules of microlearning feasible and useful in improving knowledge of clinicians?</p></div><div><h3>Study Design and Methods</h3><p>The CHEST Curriculum Pathway for Asthma was published online on the American College of Chest Physicians (CHEST) learning management site in September 2022. It was derived from existing asthma education at the CHEST organization and was vetted by asthma experts. Pretests and posttests, satisfaction surveys, and user engagement data were collected.</p></div><div><h3>Results</h3><p>In the first 6 months, 523 participants engaged with the CHEST Curriculum Pathway for Asthma. Participant satisfaction was high, and participants answered 68% of the knowledge pretest correctly and 82% of the posttest correctly. Participants completed 82.8% of the individual videos that they opened. Completion rates for each asthma chapter ranged from 22.6% to 57.9%.</p></div><div><h3>Interpretation</h3><p>This educational program is, to our knowledge, the first comprehensive microlearning online curriculum issued by a medical association on asthma. Our results suggest that the CHEST Curriculum Pathway for Asthma was effective in improving knowledge and had high user satisfaction. Comprehensive online educational programs broken into microlearning components may be useful in other topics in pulmonary medicine.</p></div>","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949789224000278/pdfft?md5=36d1504b247ffeaf3e7dae6225b345e4&pid=1-s2.0-S2949789224000278-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-09-01DOI: 10.1016/j.chpulm.2024.100052
{"title":"Dynamic Digital Radiography Pulmonary Function Testing","authors":"","doi":"10.1016/j.chpulm.2024.100052","DOIUrl":"10.1016/j.chpulm.2024.100052","url":null,"abstract":"<div><h3>Background</h3><p>Common diagnostic tests for pulmonary disorders include chest radiography and pulmonary function tests (PFTs). Although essential, these tests only offer a static assessment. Chest dynamic digital radiography (DDR) integrates lung and diaphragm motion in one study with limited radiation exposure. DDR is relatively easy to obtain, but barriers to its clinical adoption include time-consuming manual analysis and unclear correlation with PFTs.</p></div><div><h3>Research Question</h3><p>Can a machine learning pipeline automate DDR analysis? What is the strength of the relationship between PFT measures and automated DDR-based lung area measurements?</p></div><div><h3>Study Design and Methods</h3><p>PFT and DDR studies were obtained in 55 participants. We developed an analysis pipeline using convolutional neural networks capable of quantifying lung areas in DDR images to generate DDR-based PFTs (dPFTs). PFT and dPFT measures were correlated in patients with normal, obstructive, and restrictive lung physiology.</p></div><div><h3>Results</h3><p>We observed statistically significant (<em>P</em> < 1 × 10<sup>-6</sup>), strong correlations between dPFT areas and PFT volumes, including total lung capacity (<em>r</em> = 0.764), FEV<sub>1</sub> (<em>r</em> = 0.591), vital capacity (<em>r</em> = 0.763), and functional residual capacity (<em>r</em> = 0.756). Automated DDR and lung shape tracking revealed differences between normal, restrictive, and obstructive physiology using diaphragm curvature indices and strain analysis measurements. Linear regressions allowed for derivation of PFT values from dPFT measurements.</p></div><div><h3>Interpretation</h3><p>Statistically significant correlations found between dPFTs and PFTs suggest that dPFTs can act as a surrogate to PFTs when these are not available or unable to be performed. This study contributes to the potential integration of DDR as a reliable alternative to PFTs.</p></div>","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949789224000187/pdfft?md5=9d2d97c098696dc1a1baf8a3c6ae782b&pid=1-s2.0-S2949789224000187-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140400217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-09-01DOI: 10.1016/j.chpulm.2024.100071
{"title":"POINT: Liquid Markers for Risk Stratification of Pulmonary Nodules, Ready for Prime Time? Yes!","authors":"","doi":"10.1016/j.chpulm.2024.100071","DOIUrl":"10.1016/j.chpulm.2024.100071","url":null,"abstract":"","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949789224000370/pdfft?md5=95f5260546ce40846f6351f049ffdf87&pid=1-s2.0-S2949789224000370-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141389423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-07-01DOI: 10.1016/j.chpulm.2024.100081
A. Goizueta, Aileen Anglin, Bruce F. Sabath
{"title":"A 53-year-old woman with stage IV non-small cell lung cancer presenting with progressive paratracheal lymphadenopathy.","authors":"A. Goizueta, Aileen Anglin, Bruce F. Sabath","doi":"10.1016/j.chpulm.2024.100081","DOIUrl":"https://doi.org/10.1016/j.chpulm.2024.100081","url":null,"abstract":"","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141716748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-07-01DOI: 10.1016/j.chpulm.2024.100084
M. Scholand, Sachin Gupta, Kevin R. Flaherty, R. Ignacio, Zhongze Li, A. Adegunsoye
{"title":"Demographic and Clinical Factors Associated with Diagnostic Confidence in Interstitial Lung Disease: Findings from the Pulmonary Fibrosis Foundation Patient Registry","authors":"M. Scholand, Sachin Gupta, Kevin R. Flaherty, R. Ignacio, Zhongze Li, A. Adegunsoye","doi":"10.1016/j.chpulm.2024.100084","DOIUrl":"https://doi.org/10.1016/j.chpulm.2024.100084","url":null,"abstract":"","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-07-01DOI: 10.1016/j.chpulm.2024.100082
Mohleen Kang, Sachin Gupta, Yi-Hsuan Tu, Karina Raimundo, Anisha M. Patel, Kevin R. Flaherty
{"title":"Impact of Pirfenidone on Patient-Reported Outcomes in Patients With Idiopathic Pulmonary Fibrosis From the Pulmonary Fibrosis Foundation Patient Registry","authors":"Mohleen Kang, Sachin Gupta, Yi-Hsuan Tu, Karina Raimundo, Anisha M. Patel, Kevin R. Flaherty","doi":"10.1016/j.chpulm.2024.100082","DOIUrl":"https://doi.org/10.1016/j.chpulm.2024.100082","url":null,"abstract":"","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CHEST pulmonaryPub Date : 2024-07-01DOI: 10.1016/j.chpulm.2024.100076
E. Decurtis, S. Kuss-Duerkop, Iara M.P. Machado, Zoe P. Stewart, Matt Jackson, E. Hasenohr, Jessica L. Crumby, S.D. Groshong, C. Coeshott, R. Harbeck, James Woodrow, R. Sandhaus, Yongbao Wang
{"title":"Pathogenic mutations conferring alpha-1 antitrypsin deficiency are accurately identified by a novel multiplexed molecular assay","authors":"E. Decurtis, S. Kuss-Duerkop, Iara M.P. Machado, Zoe P. Stewart, Matt Jackson, E. Hasenohr, Jessica L. Crumby, S.D. Groshong, C. Coeshott, R. Harbeck, James Woodrow, R. Sandhaus, Yongbao Wang","doi":"10.1016/j.chpulm.2024.100076","DOIUrl":"https://doi.org/10.1016/j.chpulm.2024.100076","url":null,"abstract":"","PeriodicalId":94286,"journal":{"name":"CHEST pulmonary","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}