Transgender health最新文献

{"title":"Impact of Gender-Affirming Care Legislation on Medical Student Plans for Residency.","authors":"Tess I Jewell, Atticus M Wolfe, Elizabeth M Petty","doi":"10.1089/trgh.2024.0180","DOIUrl":"10.1089/trgh.2024.0180","url":null,"abstract":"<p><strong>Purpose: </strong>This study explored how state policies limiting access to gender-affirming care (GAC) for youth have impacted medical student decisions and plans for residency training.</p><p><strong>Methods: </strong>We administered a cross-sectional mixed-methods survey among medical students in the United States from March 7, 2024 through April 12, 2024. Respondents were asked if and how legislation limiting access to GAC for youth has or will impact their residency plans. Quantitative analysis included descriptive statistics and multinomial logistic regression analyses that assessed factors associated with the belief that GAC-restricting legislation would, would not, or may impact the residency program they attend in the future and concern that GAC-restricting legislation may be enacted where they pursue residency. Qualitative responses were analyzed thematically with axial coding.</p><p><strong>Results: </strong>Our sample included 237 medical students. Among those who applied to residency in the 2023-2024 application cycle (<i>n</i> = 38), 55.26% reported that legislation limiting access to GAC for youth impacted the residency programs to which they applied. Among those who did not apply to residency in 2023-2024 (<i>n</i> = 199), 58.79% reported that this legislation would impact the residency program they attend in the future. In qualitative responses, respondents cited two primary concerns alone or in combination: professional opportunity and personal safety.</p><p><strong>Conclusion: </strong>State legislation limiting youth access to GAC may have broad, long-term impacts on the distribution of physicians across the United States. Further research should investigate the effect of GAC-restricting legislation on the composition, capacity, and well-being of the health care workforce.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 4","pages":"265-275"},"PeriodicalIF":1.8,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13358181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148439597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Iterative Model of Informed Consent: A Trauma-Informed Approach to Consent in Gender-Affirming Surgery.","authors":"Elijah R Castle, Rey L Daigle, Andres Cazares, Nathan Levitt, Augustus Klein","doi":"10.1089/trgh.2024.0119","DOIUrl":"10.1089/trgh.2024.0119","url":null,"abstract":"<p><p>Discourse regarding informed consent in trans health care generally addresses overarching interventions (hormones, surgery) and not specific details of these interventions (who will be involved, what kind of and where touch is required), which threatens patient autonomy and bodily agency and reinforces power imbalances inherent in health care. Pelvic care has made the case for a trauma-informed approach to informed consent, which offers a strategy to discuss these specific details and mitigate such threats. In this article, we provide guidance for how clinicians working in gender-affirming surgery can implement a trauma-informed approach to informed consent through an iterative model of informed consent.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 3","pages":"157-160"},"PeriodicalIF":1.8,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physician Follow-up Among Transgender and Gender Diverse Individuals after Psychiatric Emergency Department Visits and Hospitalizations: A Retrospective Population-Based Cohort Study.","authors":"June Sing Hong Lam, Alex Abramovich, J Charles Victor, Juveria Zaheer, Paul Kurdyak","doi":"10.1089/trgh.2024.0102","DOIUrl":"10.1089/trgh.2024.0102","url":null,"abstract":"<p><strong>Purpose: </strong>The study compared physician-based outpatient mental health care follow-up between transgender and gender diverse (TGD) individuals and the general population who had a mental health-related emergency department (ED) visit or hospitalization.</p><p><strong>Methods: </strong>This retrospective population-based cohort study used linked health administrative data to examine all adult psychiatric patients discharged from an ED visit (ED cohort) or hospitalization (hospitalization cohort) between 2012 and 2018 in Ontario, Canada. TGD individuals were identified and their data linked with health administrative data. The primary outcome was the proportion of individuals with any outpatient physician visit for mental health reasons within 30 days of the index discharge. Multivariable logistic regression analyses examined follow-up outcomes, including by diagnostic category, with adjustment for sociodemographic and clinical factors.</p><p><strong>Results: </strong>There were 728 TGD and 581,708 general population individuals with a mental health-related ED visit, while 454 TGD and 217,507 general population individuals had a psychiatric hospitalization. TGD individuals had higher 30-day post-ED follow-up (adjusted risk ratio [aRR] =1.21; 95% confidence interval [CI]: 1.02-1.42), particularly with a psychiatrist (aRR = 1.27; 95% CI: 1.07-1.52) and for those with an anxiety and related disorder diagnosis (aRR = 1.63; 95% CI: 1.23-2.15). Meanwhile, TGD individuals had lower 30-day follow-up posthospitalization (aRR = 0.80; 95% CI: 0.66-0.98) after adjusting for covariates.</p><p><strong>Conclusions: </strong>TGD individuals had greater rates of post-ED mental health follow-up, particularly with a psychiatrist, but lower rates of follow-up after a hospitalization. The higher follow-up after ED visits likely reflects greater clinical need. Lower follow-up after hospitalization is concerning given the risk of adverse outcomes and requires further research.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 3","pages":"172-184"},"PeriodicalIF":1.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Cost-Effectiveness and Cost Savings of Gender-Affirming Mastectomy.","authors":"Brian J Conway, Alexandra O Polovneff, Emily McGinley, Conner J McMains, Liliana E Pezzin, Kate B Krucoff","doi":"10.1089/trgh.2024.0123","DOIUrl":"10.1089/trgh.2024.0123","url":null,"abstract":"<p><strong>Purpose: </strong>Gender-affirming surgery (GAS) improves both physical and mental health in transgender and gender-diverse individuals. However, access to GAS in the United States is hindered by unreliable insurance coverage and the geographically limited availability of gender-affirming surgeons. This study aimed to demonstrate the cost-effectiveness of gender-affirming mastectomy to encourage more routine insurance coverage.</p><p><strong>Methods: </strong>A cost-effectiveness analysis was performed using a Markov model with a willingness-to-pay threshold of $50,000/quality-adjusted life year (QALY). The two main arms of the Markov model were access to, or lack of access to, mastectomy followed by additional sub-arms for negative or positive health events. Data on health event probability, quality of life, and cost were extracted from the 2015 US Transgender Survey Report, a large Midwest academic health system, and published literature.</p><p><strong>Results: </strong>Compared with no mastectomy ($14,195, 1.13 QALYs), gender-affirming mastectomy resulted in a greater annual cost and effectiveness ($22,438, 1.46 QALYs) with an incremental cost-effectiveness ratio (ICER) of $24,979/QALY in the second year. By the seventh year of the model and beyond, mastectomy was less costly while still remaining more effective than lack of surgery (ICER $-85/QALY).</p><p><strong>Conclusions: </strong>Our findings indicate that gender-affirming mastectomy is cost-effective in the second-year post-surgery and modeled to save the health care system money seven years after surgery. These results imply that the provision of gender-affirming mastectomy services results in better outcomes at a lower cost, making the business case for public policymakers and private third-party payers to expand their coverage.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 3","pages":"185-195"},"PeriodicalIF":1.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiota, Gender-Affirming Hormone Therapy, and Inflammatory Biomarkers in Transgender Women with HIV: Potential Implications for Cardiovascular Disease.","authors":"Tiffany R Glynn, Courtney A Broedlow, Violeta Rodriguez, Nicholas Fonseca Nogueira, Valeria Londono, Theodora Brophy, Suresh Pallikkuth, Margaret Roach, Savita Pahwa, Lydia A Fein, Barry E Hurwitz, Deborah Jones, Maria L Alcaide, Nichole Klatt, Claudia Martinez","doi":"10.1089/trgh.2024.0042","DOIUrl":"10.1089/trgh.2024.0042","url":null,"abstract":"<p><strong>Purpose: </strong>The intersecting disparities of human immunodeficiency virus (HIV) and cardiovascular disease (CVD) among transgender women have raised questions about the role of the gut microbiota and gender-affirming hormone therapy (GAHT) in the pathogenesis of CVD in the context of HIV. The purpose of this study was to provide an early exploration of the associations between these possible mechanisms driving inflammatory CVD risk markers among transgender women with HIV.</p><p><strong>Methods: </strong>We conducted a preliminary study with 21 transgender women with HIV exploring the relationship between GAHT use (self-report), gut/rectal microbiota composition (rectal swabs), and inflammatory markers linked to CVD (plasma). Microbiota measures included alpha (richness, evenness, and Shannon diversity) and beta (Bray-Curtis, un/weighted UniFrac) diversity metrics. Inflammatory biomarkers included intestinal fatty-acid binding protein, monocyte chemoattractant protein-1, soluble CD163, intercellular adhesion molecule 1, tumor necrosis factor alpha (TNFa), soluble TNF receptor I (sTNF-I), sTNF-II, interleukin (IL)-6, IL-8, IL-1b, IL-1a, soluble CD14, d-dimer (domain dimer), vascular cell adhesion molecule 1, and high-sensitivity C-reactive protein. Wilcoxon rank sum test, log-level regression, Spearman's rho, permutational multivariate analysis of variance, and differential abundance testing assessed relationships between constructs.</p><p><strong>Results: </strong>Key inflammatory markers linked to CVD were associated with GAHT use-an increased sTNF-I and sTNF-II levels and decreased IL-1a levels. Microbiota composition was not related to GAHT use but was variably associated with inflammatory biomarkers related to CVD risk.</p><p><strong>Conclusions: </strong>Although preliminary, these findings suggest a potential association between inflammation linked to CVD risk and microbiota composition and GAHT. The results contribute to the characterization of interconnecting factors that may inform understanding and interventions to enhance overall health and well-being in transgender women with HIV. Further research is essential to elucidate the mechanisms underlying these associations, ultimately striving for health equity.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 2","pages":"114-125"},"PeriodicalIF":1.8,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alterations in Body Fat and Composition Among Thai Transmasculine Individuals Undergoing Short-Term Testosterone Therapy.","authors":"Panachai Nimitpanya, Krasean Panyakhamlerd, Ammarin Suwan, Vichadet Vichuladda, Sira Vachatimanont, Thanapob Bumphenkiatikul, Punika Panichaya","doi":"10.1089/trgh.2023.0244","DOIUrl":"10.1089/trgh.2023.0244","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the early impacts of masculinizing hormone therapy on body composition among testosterone-naive Thai transmasculine (TM) individuals, focusing on changes in fat and lean mass within the initial 3-6 months of treatment.</p><p><strong>Methods: </strong>In total, 32 participants were enrolled in this prospective study, receiving a 6-month course of 250-mg intramuscular testosterone enanthate. The assessment included whole-body dual X-ray absorptiometry, alongside anthropometric and laboratory evaluations.</p><p><strong>Results: </strong>After 6 months of testosterone administration, a significant reduction in total fat mass (FM) was observed (-4.5%; 95% confidence interval [CI] -8.5 to -0.5). Concurrently, there was an increase in total fat-free mass (FFM) (7.0%; 95% CI 3.3 to 10.8). Stratifying participants based on the World Health Organization Asian obesity criteria (body mass index <23 kg/m² for normal and ≥23 kg/m² for overweight-obesity), an elevation in FFM was observed in both categories, with a significant FM reduction only among individuals with obesity. Additional findings included hemoconcentration, reduced high-density lipoprotein cholesterol (HDL-C), and a decline in sex hormone-binding globulin (SHBG).</p><p><strong>Conclusions: </strong>Within a brief timeframe of testosterone therapy, a substantial decrease in FM and an increase in FFM were noted. Notably, this reduction in FM was more prominent in participants with obesity. Various alterations in laboratory parameters, such as hemoconcentration, reduced HDL-C, and diminished SHBG, were attributed to changes in hepatic metabolism and pituitary suppression induced by exogenous testosterone. These findings contribute valuable insights into the nuanced effects of hormone therapy on body composition among the TM population. Clinical Trial Registration Number-TCTR20241004001.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 3","pages":"196-205"},"PeriodicalIF":1.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonmedical Gender-Affirming Supports and Resources Most Desired by Transgender and Non-Binary Adolescents.","authors":"Kevin Bocek, Nicole F Kahn, Peter G Asante, Tumaini R Coker, Kacie M Kidd, Dimitri A Christakis, Wanda Pratt, Laura P Richardson, Gina M Sequeira","doi":"10.1089/trgh.2024.0084","DOIUrl":"10.1089/trgh.2024.0084","url":null,"abstract":"<p><strong>Purpose: </strong>Nonmedical gender-affirming interventions, or social transition, for transgender and non-binary (TNB) adolescents are associated with positive physical and mental health outcomes. The purpose of this study was to identify the nonmedical support needs of greatest interest to TNB adolescents and explore how these interests vary by demographic characteristics.</p><p><strong>Methods: </strong>Adolescents aged 13-17 whose gender identity or pronouns differed from their sex assigned at birth in the electronic health record were recruited to complete an electronic survey, which asked them to indicate their levels of interest in various nonmedical gender-affirming interventions on a five-point Likert scale. Descriptive statistics were used to identify nonmedical supports of greatest interest, and <i>t</i>-tests evaluated whether these varied by demographic characteristics.</p><p><strong>Results: </strong>TNB adolescents (<i>n</i> = 338) were most interested in legal name change (3.63 ± 1.87), seeing a therapist with experience caring for TNB youth (3.47 ± 1.70), and talking to a TNB adult (3.23 ± 1.63). Various significant differences emerged when comparing demographic groups, particularly among those who identified as non-binary, Black or African American, Asian, rural, and who were not out about their gender identity to their parents.</p><p><strong>Conclusion: </strong>Findings from this study can inform future research and intervention development focused on the provision of nonmedical supports to TNB adolescents in diverse communities to improve their mental health and well-being.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 2","pages":"106-113"},"PeriodicalIF":1.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural Adaptation and Evaluation of Evidence for Validity of a Gender Minority Stress Measure Among Transgender Women and Transfeminine People in China.","authors":"Willa Dong, Yongjie Sha, Weiming Tang, Joseph D Tucker, Will J Hall, Lisa B Hightow-Weidman, Edwin Fisher, Alexandra F Lightfoot, Xi Huang, Kathryn E Muessig","doi":"10.1089/trgh.2024.0028","DOIUrl":"10.1089/trgh.2024.0028","url":null,"abstract":"<p><strong>Purpose: </strong>Gender minority stress is a culturally situated, complex construct. Despite high levels of gender minority stress reported by transgender and gender-diverse (TGD) people in mainland China, measurement of this construct in this setting is not well understood. We conducted cultural adaptation of a gender minority stress measure (discrimination, rejection, victimization, nonaffirmation of gender identity, internalized transphobia, negative expectations for the future, and nondisclosure of gender identity subscales) and evaluated evidence of validity and reliability in a sample of Chinese transgender women, transfeminine people, and other gender-diverse people assigned male at birth (<i>n</i> = 277).</p><p><strong>Methods: </strong>Community-engaged cultural adaptation included needs assessment, cognitive interviewing, translation, and community and academic expert consultation. Participants (<i>n</i> = 277) completed an online questionnaire assessing seven stress subscales adapted from the Gender Minority Stress and Resilience (GMSR) measure (November 2019-June 2020). We conducted confirmatory factor analyses to confirm the underlying structure and examined divergent and criterion validity.</p><p><strong>Results: </strong>A confirmatory factor analysis found that a first-order seven-factor model had adequate fit and was more appropriate than a second-order model. The seven subscales had positive correlations with each other of under 0.60, which supported the divergent validity hypothesis. However, while all subscales were positively correlated with depressive symptoms, only nonaffirmation was correlated with cigarette use, suggesting partial support for the criterion validity hypothesis.</p><p><strong>Conclusion: </strong>Results suggest good evidence for validity of the GMSR stress subscales and support its future use among other Chinese TGD populations. Community-engaged methods may be beneficial for adapting complex measures across settings.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 2","pages":"126-136"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving HIV Care Among Transgender Women in Argentina: A Longitudinal Study on HIV-Related Outcomes.","authors":"Pablo D Radusky, Inés Aristegui, Paola Beato Fernández, Nadir Cardozo, Mariana Duarte, Solange Fabian, Emanuel Dell'Isola, Maria L Alcaide, Violeta J Rodriguez, Omar Sued, Chloe J Kaminsky, Deborah L Jones","doi":"10.1089/trgh.2024.0038","DOIUrl":"10.1089/trgh.2024.0038","url":null,"abstract":"<p><p>In Argentina, transgender women (TW) have the highest HIV prevalence (34%) among key populations, reporting challenges in adherence to antiretroviral therapy (ART) and HIV care. Physician-delivered motivational interviewing (MI) was examined for its impact on HIV-related outcomes. Multilevel models found an increase in patient-provider communication and self-reported ART adherence over 24 months in 41 TW re-engaged in HIV care. About one-third (37%) of participants were retained in care at 24 months, and 55% achieved viral suppression at follow-up. Data supporting a link between MI and these improvements are inconclusive, and targeted interventions are needed in this population. Trial Registration Number: NCT02846350.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 4","pages":"276-281"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13358173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148439556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Application of the Pantheoretical Framework of Dehumanization to Understanding Self-Injury Among Trans Young People: A Systematic Review.","authors":"Kirsty Hird, Penelope Hasking, Mark Boyes, Larissa Marion, Sylvanna Mirichlis, Sophie Haywood, Adrienne Wilmot, Kassandra Hon, Katrina Hon, Penelope Strauss","doi":"10.1089/trgh.2023.0200","DOIUrl":"10.1089/trgh.2023.0200","url":null,"abstract":"<p><p>Nonsuicidal self-injury (NSSI), the deliberate injury of one's own body without suicidal intent, is notably prevalent among trans young people. This may be attributed to the unique adversities commonly faced by trans young people, including transphobic experiences, poor body image, and gender dysphoria. The Pantheoretical Framework of Dehumanization offers an explanation of why these adversities may drive negative outcomes, including NSSI, among trans individuals. In an application of this framework, we present a systematic review of relationships between transphobic experiences, body image, gender dysphoria, and NSSI among trans people under the age of 25. We searched PsycINFO, PsycArticles, MEDLINE, Web of Science, and ProQuest. Study quality was assessed using JBI Critical Appraisal Checklists. Our findings are presented in narrative synthesis. Eleven studies were included in the review. Consistent with the Pantheoretical Framework, our findings indicate that trans young people engage in NSSI to cope with transphobic stigma and feelings of gender dysphoria. Two studies found an association between NSSI and body image concerns, although a third study had conflicting findings. A lack of research in this area underscores the need for future studies to further explore the factors contributing to NSSI among trans youth and better understand the behavior. Transphobic experiences, body image, and gender dysphoria all appear to play a role in NSSI among trans young people. However, further research is needed to understand how these factors may work together to drive self-injurious behavior, as proposed by the Pantheoretical Framework.</p>","PeriodicalId":94256,"journal":{"name":"Transgender health","volume":"11 3","pages":"161-171"},"PeriodicalIF":1.8,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}