{"title":"Thoughts on the Passing of Dr John Geddes.","authors":"S W Webb, J A Purvis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"40-41"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First steps down the slippery slope?: An analysis of the slippery-slope argument and its application to the question of assisted suicide.","authors":"Michael Trimble","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>On 29 November 2024, the House of Commons voted in favour of legalising assisted suicide. The aim of the Bill is to \"allow adults who are terminally ill, subject to safeguards and protections, to request and be provided with assistance to end their own life.\" At the time of writing, the Bill is under consideration at the Committee stage. This paper considers the implications of the bill and the appropriateness of using the \"slippery slope\" argument in its critique. It may be seen that when considering the practice of assisted suicide in jurisdictions where it has been legalised, the empirical form of the argument is shown to be valid. However, the logical form of the argument is less relevant as, once the principle is conceded, there are no further significant barriers and the slope is, in fact, a cliff edge. History shows that the proposed safeguards are unlikely to be robust or sufficient to withstand challenge.</p>","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"42-46"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The New Absence.","authors":"David J Armstrong","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial Intelligence in Endoscopy: A Narrative Review.","authors":"C E Tham, D Rea, T C Tham","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"16-23"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ankita Dash, Art O'Hagan, Kristofer Holte, John Joseph Friel, Lakshmi Venkatraman
{"title":"An Atypical Presentation of VEXAS Syndrome: A Diagnostic Conundrum.","authors":"Ankita Dash, Art O'Hagan, Kristofer Holte, John Joseph Friel, Lakshmi Venkatraman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>VEXAS syndrome is a rare and recently identified autoinflammatory disorder recently, characterized by the involvement of multiple organ systems, with manifestations in dermatology, hematology, and rheumatology. The syndrome results from a somatic mutation in the UBA1 gene, leading to defective ubiquitin-mediated protein degradation, which triggers a cascade of inflammatory responses. We report the case of a 76-year-old male who presented with a recurrent rash initially suggestive of Sweet's syndrome. Following a comprehensive diagnostic workup, including genetic testing, the patient was diagnosed with VEXAS syndrome due to the identification of a pathogenic variant in the UBA1 gene. This case highlights the diagnostic challenges clinicians face when confronting rare syndromes with nonspecific clinical features. The absence of formal diagnostic criteria and its overlap with more common inflammatory and haematologic diseases complicates prompt diagnosis and management. Timely recognition, genetic confirmation, and early intervention are critical for preventing disease progression and improving outcomes in VEXAS patient.</p>","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"24-27"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Cancer Pain Syndromes.","authors":"Alexandros-Gazi Bsarat","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"31-34"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Trials involving <i>Mycobacterium abscessus</i>: An update.","authors":"J E Moore, B C Millar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"28-30"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"My Himalayan Health Experience.","authors":"Sean Diamond, Sandra Van Schaeybroeck","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94250,"journal":{"name":"The Ulster medical journal","volume":"94 1","pages":"38-39"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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