{"title":"Evaluation of the Effect of Post-Curing Times on the Optical and Mechanical Properties and the Chemical Structure of Different 3D-Printed and Conventional Temporary Crown Materials.","authors":"Büşra Tosun, Nur Uysal, Alper Özdoğan, Ömer Kayır","doi":"10.11607/ijp.9377","DOIUrl":"10.11607/ijp.9377","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the effect of post-printing treatment conditions, including curing time, on the optical and mechanical properties of temporary crown (TC) materials.</p><p><strong>Materials and methods: </strong>A total of 108 specimens of TC materials (PowerResins Temp, PioNext Temporary Restoration Resin, and conventional polymethyl methacrylate (PMMA) were produced. The 3D-printed specimens were post-cured for different time durations (0, 15, 30, and 45 min) (n = 11). During the evaluation of optical properties, color measurement and translucency measurement were performed, while surface hardness and flexural strength were tested mechanically. For structural characterization, analyses were carried out using Fourier Transform Infrared Spectroscopy (FTIR) and scanning electron microscopy. Data was analyzed with an analysis of variance (ANOVA) (P = .05).</p><p><strong>Results: </strong>The highest color change was observed in the PioNext Temporary Restoration Resin cured for 15 minutes (11.81 ± 0.95), while the lowest was in the non-cured PowerResins Temp group (1.93 ± 0.38) (P < .001). Hardness and flexural strength increased significantly with curing duration (P < .001). FTIR analysis revealed optimal polymerization at 30 min, suggesting this duration offers a clinically favorable balance of mechanical, optical, and chemical properties.</p><p><strong>Conclusions: </strong>Both post-curing times and different production techniques affected the microstructural, optical, and mechanical properties of the tested samples. Although longer curing time improved the mechanical properties of the materials, chemical analysis showed that 45 min of curing negatively affected the polymerization. Moreover, curing for 30 min had a positive effect on the mechanical properties without changing the chemical structure of the samples.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-31"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sakineh Nikzad, Azin Zare, Faezeh Atri, Dana Jafarpour, Shahram Zare, Abbas Azari
{"title":"Effect of Different Concentrations of Nano Hydroxyapatite on the Microshear Bond Strength of Zirconia to Resin Cement.","authors":"Sakineh Nikzad, Azin Zare, Faezeh Atri, Dana Jafarpour, Shahram Zare, Abbas Azari","doi":"10.11607/ijp.9205","DOIUrl":"10.11607/ijp.9205","url":null,"abstract":"<p><strong>Statement of problem: </strong>The impact of varying thicknesses and densities of nano hydroxyapatite (n-HA) coating on the microshear bond strength (μSBS) of zirconia ceramics to resin cements is not well investigated.</p><p><strong>Purpose: </strong>This study aimed to assess the impact of nano hydroxyapatite coating of different concentrations on the microshear bond strength of zirconia ceramics to resin cements.</p><p><strong>Materials and method: </strong>48 Cercon Y-TZP blocks (4×4×4 mm) were randomly divided into 4 groups (n=12); 1) Control group, 2) 5gr n-HA coating, 3) 10gr n-HA coating, and 4) 15gr n-HA coating. The specimens were sintered at 1250°C. The thickness of the coatings was characterized using scanning electron microscopy (SEM). Energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD) analyses were carried out to characterize the surface. All specimens were then bonded to Panavia F2.0 cement. Microshear bond testing was carried out using a universal testing machine. Stereomicroscope imaging was used to evaluate the zirconia surface failure mode. The data were analyzed using Kruskall-wallis and Mann-whitney test and P<0.05 was considered statistically significant.</p><p><strong>Results: </strong>The mean μSBS value of the 5gr n-HA coated group with a thickness of 7.71±2.51 micron was 28.30±3.02 Mpa, which was significantly higher than the control group with the mean value of 19.94±1.86 Mpa (P<0.05). The mean μSBS value of the 10gr and 15gr n-HA with thicker coatings were 21.66±3.63 Mpa and 15.23±3.34 Mpa, respectively. Additionally, the main mode of failure for the 5gr n-HA group was a mixed failue. In contrast, the adhesive mode of failure was more dominant in the control group. EDS and XRD analysis revealed the formation of crystalline HA on zirconia blocks, highlighting the predominant zirconia peak at 32°. The SEM analysis of the coated specimens displayed a uniform layer of n-HA coating with evident cracks which were filled with the resin cement. These cracks themselves can help increase the bond strength between ceramic and resin cement.</p><p><strong>Conclusion: </strong>A thin coating of nanocrystalline hydroxyapatite on zirconia surface can be effective in enhancing the micro shear bond strength of these ceramics to resin cements. The microshear bond strength of nHA-coated zirconia significantly improved compared to the untreated specimens.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Validation of an Occlusal Force-based Implant Surgical Guide System: Enhanced Accuracy in Edentulous Patient Treatment with Negligible Positional Deviation.","authors":"Sangjin Suh, Sichan Park, Heechul Kim, Chan Park","doi":"10.11607/ijp.9360","DOIUrl":"10.11607/ijp.9360","url":null,"abstract":"<p><p>A method for designing a 3-piece surgical guide is proposed, which incorporates patient-specific occlusal forces when fabricating digital implant surgical guides for patients with complete edentulism. This approach allows more precise vertical implant placement by incorporating the natural occlusal forces of patients into guide seating. Clinical validation of this system demonstrated improved positional accuracy compared to conventional guided surgery methods, particularly in the critical aspect of vertical positioning. This innovative approach effectively addresses the fundamental challenge of achieving precise implant placement in patients with edentulism, yielding highly predictable surgical outcomes.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco De Angelis, Matteo Buonvivere, Camilla Mancini, Giuseppe Daniele Rondoni, Mirco Vadini, Camillo D'Arcangelo
{"title":"Influence of Dentin Bonding and Interfacial Adhesion on the Flexural Properties of a 4 Mol% Yttria Partially Stabilized Zirconia.","authors":"Francesco De Angelis, Matteo Buonvivere, Camilla Mancini, Giuseppe Daniele Rondoni, Mirco Vadini, Camillo D'Arcangelo","doi":"10.11607/ijp.9283","DOIUrl":"10.11607/ijp.9283","url":null,"abstract":"<p><strong>Purpose: </strong>4 mol% yttria partially stabilized zirconia (4Y-PSZ) offers improved translucency compared to 3% tetragonal polycrystalline zirconia but lacks transformation toughening, which may affect its flexural strength. Since adhesive luting was shown to improve mechanical performances of all-ceramic materials, this research evaluated the influence of different cements on the 3-point flexural strength of a 4Y-PSZ bonded to bovine dentin.</p><p><strong>Materials and methods: </strong>Thirty 1-mm-thick dentin slices were obtained from bovine incisors, paired with 1-mm-thick 4Y-PSZ slices, then divided into three groups (n=10) based on the cement investigated: a 10-MDP-free self-adhesive resin cement (SA), a 10-MDP-based adhesive resin cement (MDP-A), and a conventional glass ionomer cement (GI). After luting, the obtained assemblies were cut to obtain 1-mm-wide bar-shaped specimens, which were subjected to 3-point bending test. Fracture loads and flexural strength were recorded, and the modes of failure were analyzed.</p><p><strong>Results: </strong>The highest fracture load and flexural strength were observed in the MDP-A group (76.5 N and 401.5 MPa), followed by the SA group (62.3 N and 326.8 MPa). The GI group exhibited the lowest values (45.6 N and 239.5 MPa). In MDPA group samples predominantly exhibited concurrent dentin and zirconia fractures without debonding, while in SA and GI groups a frequent incidence of debonding at the interface was observed.</p><p><strong>Conclusion: </strong>Adhesive cementation enhances the flexural strength of 4Y-PSZ bonded to bovine dentin, with the 10-MDP-based resin cement yielding the best performances. Effective adhesive techniques could improve the mechanical performance of 4Y-PSZ restorations, making them more reliable for clinical applications.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"INfORM/IADR Key Points for Good Clinical TMD Practice - A Critical Comment.","authors":"Jens Christoph Türp, Güzin Neda Hasanoğlu Erbaşar","doi":"10.11607/ijp.9336","DOIUrl":"10.11607/ijp.9336","url":null,"abstract":"<p><strong>Purpose: </strong>To critically evaluate the recently published INfORM/IADR consensus paper containing ten key points for good clinical practice in the management of patients with temporomandibular disorders.</p><p><strong>Materials and methods: </strong>After perusing the text of the document, followed by intensive discussion, the 10 key points were carefully analyzed and commented.</p><p><strong>Results: </strong>Two key points could be replaced by other (clinically relevant) statements. In addition to terminologically and semantically imprecise formulations some verbal descriptions remain superficial and vague. While no distinction was made between acute and chronic TMDs, the INfORM/IADR author group differentiates between first-line and second-line therapeutic modalities without explaining the rationale for such a classification. Furthermore, no medication recommendations were made.</p><p><strong>Conclusions: </strong>We anticipate that the INfORM/IADR publication will have a beneficial impact on the care of TMD patients. However, in our opinion, a reflection on some of the contents of the 10-point document seems justified in order to reduce the risk of misinterpretation of some statements, which could lead to inappropriate diagnostic and therapeutic measures.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stress Distribution on Mucosa Soft Tissue of Alveolar Ridge at the Dislocation of BPS: A Three-Dimensional Finite Element Analysis.","authors":"Sheng Fang, Kailun Chen, Xiaohan Lin, Zhu Tie, Ziqin Lin, Junjie Lin, Rui He, Botao Wang","doi":"10.11607/ijp.9312","DOIUrl":"10.11607/ijp.9312","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the stress distribution and displacement of alveolar ridge mucosal tissue when Biofunctional prosthetic system (BPS) dentures were dislocated under three conditions.</p><p><strong>Materials and methods: </strong>CBCT was used to obtain the data of the patient's jaw, and the patient's BPS scan data was gained through the oral scanner. Through Mimics, Geomagic Studio and Unigraphics NX software, the CT data files were built into 3D finite element models (FEM) of the upper and lower edentulous jaws, mucosa and BPS complete dentures, then analyze the stress distribution and mucosal tissue displacement caused by ridge mucosal tissue when BPS dentures were dislocated under three conditions (BPS denture dislocation along the anterior alveolar ridge, BPS denture dislocation caused by the left posterior teeth biting hard food or anterior teeth biting hard food), respectively.</p><p><strong>Results: </strong>In general, under the three different circumstances, the value in the relatively large area of the maxillary and mandibular equivalent stress was similar, but the deformation value of the mandibular mucosa was significantly higher than that of the maxillary mucosa.</p><p><strong>Conclusion: </strong>When BPS complete denture is dislocated, the stress distribution of the mucosa under the base of the maxillary and mandibular dentures is uniform and extensive, and the stress distribution of the palatal mucosa is small. In comparison to the dislocation of BPS dentures that were removed and worn independently, the mucosal stress distribution was more uneven when BPS dentures were subjected to biting hard food, resulting in greater deformation.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ho-Jin Lee, Seok-Hwan Cho, Chonghwa Kim, Hang-Nga Mai, Thaw Thaw Win, Shilpa Rana, Du-Hyeong Lee
{"title":"Effects of Post-Curing Duration on Color Changes in 3D-Printed Fixed Polymeric Restorations of Varying Thicknesses.","authors":"Ho-Jin Lee, Seok-Hwan Cho, Chonghwa Kim, Hang-Nga Mai, Thaw Thaw Win, Shilpa Rana, Du-Hyeong Lee","doi":"10.11607/ijp.8982","DOIUrl":"10.11607/ijp.8982","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate color changes in 3D-printed acrylic restorations of varying thicknesses and exposed to different post-curing durations.</p><p><strong>Materials and methods: </strong>Three virtual full-contour maxillary central incisor crowns with different buccal thicknesses (1.0, 1.5, and 2.0 mm) were designed and manufactured using a 3D printer and a photopolymer (n = 9 per thickness group). The lightness, hue, and chroma of the restorations were measured at baseline (prior to post-curing) and again at 5 min intervals up to 30 min during the post-curing process using a spectrophotometer. Color changes (ΔE) were calculated by comparing the CIE L*, a*, b* coordinates at different time points to the baseline values. Repeated-measures analysis of variance and the Tukey's post-hoc test were used for statistical analysis (α = .05).</p><p><strong>Results: </strong>The ΔE increased significantly within the first 5 min of post-curing and was more gradual thereafter in all thickness groups. The ΔE values were significantly higher in the 1.5 and 2.0 mm thickness groups compared to the 1.0 mm thickness group. The C* coordinate was seen to increase significantly within the first 5 min of post-curing, and did not change significantly afterward.</p><p><strong>Conclusions: </strong>During post-curing, the hue of a 3D printed polymeric restoration changed to yellowish and reddish shades, the brightness decreased, and the saturation increased. Most color changes occurred within the first 5 min of post-curing and were also more noticeable in thicker restorations.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-18"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omnia M Refai, Yasmine Said Elsherbeeny, Amany Mostafa Saad Farahat
{"title":"Comparison of Retention Between Different Duplication Techniques: Conventional Versus CAD/CAM: A Within Subject Controlled Clinical Trial.","authors":"Omnia M Refai, Yasmine Said Elsherbeeny, Amany Mostafa Saad Farahat","doi":"10.11607/ijp.9274","DOIUrl":"10.11607/ijp.9274","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare retention and occlusal force distribution between conventional and two three-dimensional (3D) printed computer-aided design and computer-aided manufacturing (CAD/CAM) duplication techniques for refitted maxillary complete dentures.</p><p><strong>Materials and methods: </strong>Twenty completely edentulous individuals with preexisting complete dentures participated in this within-subject controlled clinical trial. Dentures were duplicated using three methods: Group I (conventional duplication), Group II (3D printing to create a separate base made of pink polymethyl methacrylate (PMMA) and teeth made of tooth-colored PMMA teeth), and Group III (3D printing of a single unit denture with a veneered base made of pink photo-curable resin). Occlusal force distribution was measured for the reference denture before duplication. Retention and occlusal force distribution were measured at the time of denture insertion. A one-way analysis of variance (ANOVA) was used for group comparisons, and Bonferroni's post hoc test was utilized for multiple comparisons.</p><p><strong>Results: </strong>The highest mean retention was observed in Group II (36.53±3.75), followed by Group III (35.01±3.41) and Group I (27.95±4.32) with a statistically significant difference between Group I and the other two Groups. For occlusal force distribution, the highest mean difference was recorded in Group I (14.35±3.25), followed by Group II (7.60±1.84) and Group III (3.82±0.91) in comparison to the reference denture with a statistically significant difference (P=0.001).</p><p><strong>Conclusion: </strong>Within the study's limitations, 3D-printed dentures showed superior retention and more balanced occlusal force distribution compared to conventional methods. These findings imply that 3D printing technology may improve prosthodontics' ability to construct duplicate dentures.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-27"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor de Melo Soares, Andréa Cândido Dos Reis, Mariana Lima da Costa Valente
{"title":"Influence of Printing Angle on The Physico-Mechanical Properties of PMMA-Based Resins for Dental Use: A Systematic Review of in Vitro Studies.","authors":"Victor de Melo Soares, Andréa Cândido Dos Reis, Mariana Lima da Costa Valente","doi":"10.11607/ijp.9169","DOIUrl":"https://doi.org/10.11607/ijp.9169","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the influence of printing angle on the physico-mechanical properties of PMMA.</p><p><strong>Material and methods: </strong>This systematic review included the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA 2020) and was registered with the Open Science Framework (osf.io/y4qm8). Electronic searches were carried out in the PubMed/Medline, Scielo, Scopus, Embase and Science Direct databases. Risk of bias was analyzed using the Joanna Briggs Institute (JBI) instrument for quasi-experimental studies.</p><p><strong>Results: </strong>Of the 1917 studies identified, 25 were included and qualitatively assessed after the selection stages. Printing dental devices for prosthetic use in PMMA-based resins provides satisfactory performance, with better resistance to bending and fracture at 0°. After polishing, the differences observed in surface roughness concerning the printing angle became insignificant. The different printing angles can influence the optical properties significantly, but other factors such as the composition of the resin can influence these results.</p><p><strong>Conclusion: </strong>Printing dental devices in PMMA-based resins provides satisfactory performance for prosthetic use. In general, better mechanical performance was attributed to 0° compared to 45° and 90°. Varying the printing angle can be a strategy for individualizing prosthetic devices according to the physical and mechanical needs presented by each type of clinical application.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-24"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonography: A Potential Tool for Diagnostic and Interventional Applications in Prosthodontics.","authors":"Leonardo Mancini, Daniel S Thoma","doi":"10.11607/ijp.9445","DOIUrl":"https://doi.org/10.11607/ijp.9445","url":null,"abstract":"<p><p>The aim of this report is to highlight the potential of high-frequency ultrasonography (HFUS) as a diagnostic and interventional tool in fixed prosthodontics. HFUS enables a minimally invasive evaluation of the buccal, palatal, or lingual aspects, providing both transverse and horizontal sections of teeth and/or implants sites. By applying a conductive gel, bone, soft tissues, roots, implants, abutments, and crowns profiles can be effectively visualized. This approach might reduce the reliance on ionizing radiation while enhancing diagnostic accuracy and procedural predictability. High-frequency ultrasound (HFUS) demonstrates significant potential to advance clinical research and expand prosthodontic applications by providing a safe, non-invasive, and user-friendly imaging modality.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}