The Canadian journal of hospital pharmacy最新文献

{"title":"Motivation of Hospital Pharmacists Regarding the Transfer of Knowledge in Geriatrics (MOTIVPHARM-G).","authors":"Olivier Beauparlant Lamarre, Mélina Del Bianco-Rondeau, Laurie Jeannotte, Caroline Spinelli, Anne Julie Frenette, Katherine Desforges","doi":"10.4212/cjhp.3873","DOIUrl":"10.4212/cjhp.3873","url":null,"abstract":"<p><strong>Background: </strong>To foster equity for vulnerable populations, hospital pharmacists should be motivated to acquire new knowledge in geriatrics. No tool specifically designed to assess their motivation in this area exists.</p><p><strong>Objectives: </strong>To assess the motivation of clinical pharmacists in Quebec university hospital centres who are not experts in geriatrics to participate in a knowledge transfer strategy developed by geriatric experts.</p><p><strong>Methods: </strong>A survey, constructed using a Delphi method, was conducted from July to October 2022. The topics covered by the survey included participants' perceptions, barriers faced, and openness to participating in a knowledge transfer strategy in geriatrics.</p><p><strong>Results: </strong>Of the 703 pharmacists invited to participate, 202 (28.7%) responded to the questionnaire. The average motivation score was 78.9/108 (standard deviation 5.8). No statistically significant difference was observed between pharmacists in critical care and those in other sectors, nor were there differences related to year of graduation.</p><p><strong>Conclusions: </strong>Clinical pharmacists working in Quebec university hospital centres seemed motivated to improve their knowledge in geriatrics.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 3","pages":"e3873"},"PeriodicalIF":0.0,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13544584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Chemotherapy-Induced Peripheral Neuropathy: Development and Internal Validation of the Novel Foresight Neuro-Wing Model.","authors":"Navarat Panjasawatwong, Natharin Phattayanon, Tanakit Nantakwang, Pattaraporn Ruthamnong, Nuannapa Aurchit, Anugool Lamkhum, Nopphadol Nuntamool","doi":"10.4212/cjhp.3825","DOIUrl":"10.4212/cjhp.3825","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and debilitating side effect that significantly reduces cancer patients' quality of life, limits treatment tolerance, and can compromise treatment efficacy. Accurate prediction of CIPN risk is crucial for targeted interventions.</p><p><strong>Objective: </strong>To develop and validate a risk prediction model, Foresight Neuro-Wing, for identifying patients at increased risk of CIPN during chemotherapy with common cytotoxic agents.</p><p><strong>Methods: </strong>A retrospective cohort study was used to analyze the electronic medical records of patients receiving chemotherapy at a single institution. Potential risk factors (demographic characteristics, as well as cancer-related and chemotherapy-related factors) were assessed using logistic regression. Model performance was evaluated using area under the receiver operating characteristic curve and calibration plots. Internal validation involved bootstrapping and cross-validation. A classified score model stratified patients into 4 risk groups.</p><p><strong>Results: </strong>A total of 346 patients met the inclusion criteria. The incidence of CIPN was 33.5% (<i>n</i> = 116). Significant predictors included sex, underlying disease, cancer type, previous and current chemotherapy regimens, and number of chemotherapy cycles. The scoring model achieved a predictive performance of 87.33%, and the classified score model had a predictive performance of 85.93%. Decision curve analysis demonstrated that using the model to guide intervention decisions provided a greater net benefit than treating all or treating none.</p><p><strong>Conclusions: </strong>The Foresight Neuro-Wing model effectively identified patients at increased risk of CIPN. This tool has the potential to inform clinical decision-making, enabling targeted monitoring and preventive strategies, ultimately improving patient outcomes and quality of life.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 3","pages":"e3825"},"PeriodicalIF":0.0,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13544588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacists' Perceptions of Medication-Related Clinical Decision Support Alerts in an Electronic Health Record System.","authors":"Brandon Tong, Melvin Lau, Gordan Fan, Josh Batterink, Stacey Valalik, Sandra Yin","doi":"10.4212/cjhp.3802","DOIUrl":"10.4212/cjhp.3802","url":null,"abstract":"<p><strong>Background: </strong>The Clinical & Systems Transformation project implemented the Oracle Health (formerly Cerner) electronic health record system across 3 health organizations in British Columbia. Medication-related clinical decision support (CDS) alerts in such systems are intended to assist pharmacists during order verification but may contribute to alert fatigue.</p><p><strong>Objectives: </strong>To evaluate hospital pharmacists' perceptions of standard and custom CDS alerts within the pharmacist verification application of the new system, including their views on alert content, alert volume, and improvement opportunities.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted in late 2023 at the 3 health organizations, targeting pharmacists with at least 6 months of experience using the system. Quantitative data were analyzed using descriptive statistics, and qualitative responses were grouped into common themes.</p><p><strong>Results: </strong>A total of 47 responses were suitable for analysis. The majority of respondents rated CDS alert content positively. However, perceptions about the volume of alerts and overall alert satisfaction were primarily neutral. Certain custom alerts, such as those for low renal function, were rated as having high impact but were infrequently encountered.</p><p><strong>Conclusions: </strong>These findings highlight the need for ongoing optimization of CDS alerts to better support pharmacists through reduction of unnecessary alerts and improved implementation of high-impact alerts.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 3","pages":"e3802"},"PeriodicalIF":0.0,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13446725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148687259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Drug Monitoring of Vancomycin Based on Ratio of Area under the Curve to Minimum Inhibitory Concentration: A Quality Improvement Project.","authors":"Kaitlin McDougal, Vanessa Paquette, Jennifer Kendrick, Roxane Carr","doi":"10.4212/cjhp.3844","DOIUrl":"10.4212/cjhp.3844","url":null,"abstract":"<p><strong>Background: </strong>Various organizations recommend targeting a calculated ratio of area under the curve to minimum inhibitory concentration (AUC/MIC) of 400-600 for therapeutic drug monitoring (TDM) of vancomycin. Sites that have implemented AUC/MIC-based TDM for vancomycin have shown reduced vancomycin exposure, decreased nephrotoxicity rates, and fewer dosage adjustments relative to the use of trough monitoring.</p><p><strong>Objectives: </strong>To implement AUC/MIC-based TDM for vancomycin at a pediatric and obstetric tertiary care site and to assess pharmacists' knowledge and satisfaction before and 1 month after implementation and at 2-year follow-up.</p><p><strong>Methods: </strong>This quality improvement project involved the planning, implementation, and evaluation of AUC/MIC-based TDM for vancomycin. Anonymous electronic surveys were distributed to pharmacists before and after implementation and at 2-year follow-up, assessing practices, comfort, knowledge, and satisfaction with AUC/MIC-based TDM.</p><p><strong>Results: </strong>Implementation of AUC/MIC-based TDM for vancomycin occurred in April 2021, after 8 months of preparation during which educational sessions, a dosing calculator, guidelines, and written communications were developed and delivered. Surveys were partially or fully completed by 27 pharmacists before implementation, by 24 pharmacists at 1 month after implementation, and by 32 pharmacists at 2-year follow-up. At 1 month and 2 years after implementation, larger proportions of respondents felt knowledgeable (88% [<i>n</i> = 21] and 81% [<i>n</i> = 26], respectively, vs 22% [<i>n</i> = 6] before implementation) and comfortable (88% [<i>n</i> = 21] and 81% [<i>n</i> = 26], respectively, vs 19% [<i>n</i> = 5] before implementation) with AUC/MIC-based TDM. Respondents' satisfaction with implementation of AUC/MIC-based TDM was 88% (<i>n</i> = 21/24) at 1 month after implementation and 94% (<i>n</i> = 29/31) at the 2-year follow-up.</p><p><strong>Conclusions: </strong>AUC/MIC-based TDM for vancomycin was implemented with high pharmacist satisfaction. Future studies at this site should investigate clinical outcomes.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 3","pages":"e3844"},"PeriodicalIF":0.0,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13446726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148687262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on Leadership Development and Learning Needs of Pharmacy Leaders in Canadian Health Care Systems: A Qualitative Study.","authors":"Heather Naylor, Wooje Choi, Michael LeBlanc, Sheri Andrews, Preshit N Ambade, Neil J MacKinnon","doi":"10.4212/cjhp.3837","DOIUrl":"10.4212/cjhp.3837","url":null,"abstract":"<p><strong>Background: </strong>Strong leaders are essential for driving progress in pharmacy practice, yet some professionals believe that pharmacy leadership in Canada is facing a crisis. While leadership training is important for developing the next generation of leaders, there is limited understanding of the skills most valued by current health care-systems pharmacy leaders, as well as uncertainty about the effectiveness of existing training pathways.</p><p><strong>Objectives: </strong>To identify the leadership skills most valued by Canadian health care-systems pharmacy leaders and to explore perceptions of existing leadership training.</p><p><strong>Methods: </strong>As part of a mixed-methods study, virtual focus groups, based on a semistructured interview guide, were conducted with health care-systems pharmacy leaders from across Canada. Data were analyzed using reflexive thematic analysis.</p><p><strong>Results: </strong>Three focus groups (involving a total of 17 participants) were held in July 2024. The leadership skills most valued by participants were strong interpersonal skills, systems thinking, relationship-building, ability to prioritize, ability to delegate, self-awareness, and ability to coach others. Most participants had learned leadership skills on the job or through workplace-based training programs; however, these methods were considered inadequate to meet development needs. Enablers for improving leadership development included pharmacy-focused leadership training programs, mentorship, peer-support networks, guidance from professional organizations on training resources, encouragement of leadership potential in others, and provision to staff members of projects that challenge them beyond their current level of knowledge or skill.</p><p><strong>Conclusion: </strong>Improving health care-systems pharmacists' preparedness for leadership appears to require a comprehensive strategy. Suggested key approaches include increasing access to formal pharmacy-specific leadership training programs, providing mentorship, offering \"stretch\" opportunities, and strengthening support from professional organizations to guide development of the next generation of pharmacy leaders.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 3","pages":"e3837"},"PeriodicalIF":0.0,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13340459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leadership and Managerial Development Needs of Pharmacy Leaders in Canadian Health Care Systems: Results from a National Questionnaire.","authors":"Heather Naylor, Wooje Choi, Michael LeBlanc, Sheri Andrews, Preshit N Ambade, Breagh H MacKinnon, Neil J MacKinnon","doi":"10.4212/cjhp.3836","DOIUrl":"10.4212/cjhp.3836","url":null,"abstract":"<p><strong>Background: </strong>The scope of pharmacy practice in Canada is expanding, as are the responsibilities of health care-systems pharmacy leaders. However, there is limited knowledge of the training pathways used by current pharmacy leaders and the leadership and managerial skills they value most.</p><p><strong>Objectives: </strong>To identify key leadership skills valued by Canadian pharmacy leaders and to determine the development pathways for these skills.</p><p><strong>Methods: </strong>An electronic survey on leadership and management competencies was distributed in spring 2024 to health care-systems pharmacy leaders across Canada. Descriptive statistics, one-way analysis of variance, and linear regression were used to assess the associations between the self-reported skill deficit and sociodemographic and employment-related factors in the quantitative data.</p><p><strong>Results: </strong>A total of 141 pharmacy leaders answered some or all of the survey questions. Respondents were predominantly midcareer leaders in academic hospitals with up to 10 years' experience, many of whom had prior clinical leadership training. Respondents expressed confidence in their clinical or operational management skills and identified finance and budgeting, human resource management, and leadership as areas requiring further development. Every mean 1-point increase in the skill deficit was associated with a 2-point decrease in job satisfaction score (95% confidence interval -3.4 to -0.90, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>These findings suggest the need for further leadership and management training programs. It is recommended that a national pharmacy leadership and management competency framework be developed, along with leadership certification programs offering hands-on learning opportunities.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 3","pages":"e3836"},"PeriodicalIF":0.0,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13340458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un adieu aux lecteurs.","authors":"Stephen Shalansky","doi":"10.4212/cjhp.4036","DOIUrl":"https://doi.org/10.4212/cjhp.4036","url":null,"abstract":"","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 2","pages":"e4036"},"PeriodicalIF":0.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148214057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Canadian Healthcare-Systems Pharmacy Residency Graduates/Diplômés de Programmes Canadiens de Résidence en Pharmacie dans les Réseaux de la Santé.","authors":"","doi":"10.4212/cjhp.3993","DOIUrl":"https://doi.org/10.4212/cjhp.3993","url":null,"abstract":"","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 2","pages":"e3993"},"PeriodicalIF":0.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148214070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eligibility, Participation, and Matching Outcomes of International Pharmacy Graduates in Accredited Pharmacy Residency Programs in Canada: A Policy Scan and Cross-Sectional Analysis.","authors":"Mhd Wasem Alsabbagh, Deep Patel, Tim Mickleborough","doi":"10.4212/cjhp.3882","DOIUrl":"https://doi.org/10.4212/cjhp.3882","url":null,"abstract":"<p><strong>Background: </strong>International pharmacy graduates (IPGs) are underrepresented in Canadian hospitals. It has been speculated that structural factors, particularly limited access to residency programs, may contribute to IPGs' disproportionate streaming toward community pharmacy practice.</p><p><strong>Objectives: </strong>To review the criteria of accredited hospital pharmacy residency programs in Canada to determine whether IPGs are eligible to apply, to examine the extent of IPGs' participation and success in securing hospital pharmacy residency positions, and to determine the factors that influence success in the matching process.</p><p><strong>Methods: </strong>A policy scan of accredited residency programs that participate in the Canadian Pharmacy Residency Board matching program was conducted in September 2023. In addition, a descriptive cross-sectional study was performed using available application data from the Pharmacy Residency Application and Matching Service in Canada for the 2022/23 matching cycle (January 2023 match).</p><p><strong>Results: </strong>Of the 40 participating residency programs, 7 (17.5%) required graduation from a North American-accredited institution, whereas the others accepted candidates with eligibility for licensure in any Canadian province. Only one program explicitly mentioned and encouraged IPGs to apply. In the matching data, only 19 (6.2%) of 308 applicants were IPGs, of whom 3 (16%) were successfully matched to a program, whereas 131 (45.3%) of 289 domestic graduates were matched. There was a significant association between country of graduation and residency matching, with lower odds of matching for IPGs (adjusted odds ratio 0.230, 95% confidence interval 0.063-0.845).</p><p><strong>Conclusion: </strong>These results show that IPGs are substantially underrepresented in the residency application and matching processes and provides insights into potential systemic barriers that need to be addressed by policy-makers and stakeholders.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 2","pages":"e3882"},"PeriodicalIF":0.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148214043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Farewell to Readers.","authors":"Stephen Shalansky","doi":"10.4212/cjhp.4020","DOIUrl":"https://doi.org/10.4212/cjhp.4020","url":null,"abstract":"","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"79 2","pages":"e4020"},"PeriodicalIF":0.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148214039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}