The Canadian journal of hospital pharmacy最新文献

{"title":"Putting the Heart into Pharmacy: Creation and Implementation of a PharmD Cardiology Rotation in Tertiary Care.","authors":"Ashley Hermanus, Kirsten Tangedal, William Semchuk, Kari Rustad","doi":"10.4212/cjhp.3541","DOIUrl":"10.4212/cjhp.3541","url":null,"abstract":"","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3541"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Piloting a Hospital Pharmacy Performance Model in the Face of Province-Wide Implementation of Activity-Based Funding in Quebec Health Care Centres.","authors":"France Boucher, Sylvie Schryve, André Bonnici, Carl Desparois, François Paradis, Julie Racicot, Diem Vo, Benoît Lemire, Linda Vaillant","doi":"10.4212/cjhp.3590","DOIUrl":"10.4212/cjhp.3590","url":null,"abstract":"<p><strong>Background: </strong>In the face of province-wide implementation of activity-based hospital funding in Quebec, a need arose to effectively measure pharmacists' contributions along the patient care trajectory and to enable pharmacy benchmarking using valid performance indicators.</p><p><strong>Objectives: </strong>A 3-phase project was initiated to measure the performance and impact of pharmacists and pharmacy departments. Phases 2 and 3, described here, focused on gradually implementing, in various health care centres, the priority indicators selected in phase 1.</p><p><strong>Methods: </strong>The project involved multiple committees overseeing the implementation, data collection, analysis, and documentation of 18 performance indicators. Specific tools were developed to facilitate data collection and encourage pharmacists' participation. A feedback survey was used to document pharmacists' experiences.</p><p><strong>Results: </strong>Substantial data were gathered over 3 years (2017 to 2020), involving 358 pharmacists from 6 health care centres. The overall contribution rate to the daily data collection from front-line pharmacists was 55%. The feedback survey revealed that, of the various communication tools used to promote the project, in-person events were better perceived by the front-line pharmacists than online tools. Of the 183 respondents to the survey, most (94%, <i>n</i> = 172) believed it was important to collect data to document pharmacists' activities, and 82% (<i>n</i> = 150) saw the project as relevant to the upcoming activity-based funding system.</p><p><strong>Conclusions: </strong>Despite challenges, progress was made in defining relevant indicators, adjusting the list generated during phase 1, and reaching a consensus on 16 indicators. Stakeholders expressed interest, emphasizing the importance of documenting pharmacists' activities. The project has laid the foundation for demonstrating the value of pharmacists along the patient care trajectory and measuring pharmacy departments' performance. However, more integrated technological solutions are needed for province-wide implementation.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3590"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Discharge Opioid Prescription and Consumption Following Surgery: The POPCORN Observational Study\".","authors":"","doi":"10.4212/cjhp.3725","DOIUrl":"https://doi.org/10.4212/cjhp.3725","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.4212/cjhp.3574.].</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3725"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les traitements traditionnels et les compléments alimentaires chez le patient atteint de cancer: État des lieux en Tunisie.","authors":"Nawres Makhlouf, Imen Ben Jedidia, Marwa Bel Haj Ali, Mariem Chedly, Amani Cherif","doi":"10.4212/cjhp.3586","DOIUrl":"10.4212/cjhp.3586","url":null,"abstract":"<p><strong>Context: </strong>Alternative and complementary medicines are currently experiencing a real boom worldwide, especially among cancer patients who are looking to improve their physical and mental well-being.</p><p><strong>Objectives: </strong>To provide an overview of the use of traditional treatments and dietary supplements by cancer patients and to assess the impact of these approaches on cancer care.</p><p><strong>Methods: </strong>This prospective cross-sectional descriptive study was conducted at the oncology day hospital of a Tunisian medical centre. Data were collected from February 1 to March 30, 2022.</p><p><strong>Results: </strong>In the study population, the prevalence of complementary medicine use was 71%; users were predominantly female, and average age was 54 years. Herbal medicine was most commonly used (69.7%); animal-derived products, diet, massage therapy, and dietary supplements were also common, with percentages ranging between 20% and 40%. Cupping therapy (12.4%) and mind-body therapies (such as rokia charia and physical activity; 10%) were noted to a lesser extent. Of the plants identified, the most frequently consumed was <i>Nigella sativa</i> L. (44.9%), followed by <i>Ephedra foeminea</i> Forssk. (42.7%) and <i>Curcuma longa</i> L. (32.6%). Among the identified herb-drug interactions, 33.4% were classified as contraindicated, while 56.7% were classified as beneficial.</p><p><strong>Conclusions: </strong>The survey revealed a significant prevalence of alternative medicine use, which requires careful attention and further research.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3586"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overcoming Challenges during Breastfeeding to Prevent Perinatal HIV Transmission in Canada: A Case Series.","authors":"Rocky Lam, Jacqueline Myers, Carolyn Gray, Alexander Wong","doi":"10.4212/cjhp.3572","DOIUrl":"10.4212/cjhp.3572","url":null,"abstract":"","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3572"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Environmental Audit Tool for Hospital Pharmacy.","authors":"Caitlin Roy, Kirsten Fox, Kirsten Tangedal","doi":"10.4212/cjhp.3591","DOIUrl":"10.4212/cjhp.3591","url":null,"abstract":"<p><strong>Background: </strong>Health care contributes significantly to greenhouse gas emissions, and pharmacy departments have many opportunities to reduce their emissions.</p><p><strong>Objective: </strong>To describe the development and implementation of an environmental audit tool for hospital pharmacy departments.</p><p><strong>Methods: </strong>A pharmacy environmental audit tool was developed by modifying a generic workplace audit tool to include pharmacy-specific content. The audit tool contained 22 categories, with scoring on a 4-point scale (from 0 to 3). Members of a volunteer committee completed the audit by observing practice areas. The lowest-scoring categories were then prioritized for action.</p><p><strong>Results: </strong>Overall, the 4 main pharmacy sites in Regina, Saskatchewan, scored 23/66 (35%). Areas of strength identified in the audit included reuse of packaging materials, carpooling, and paperless meetings. Areas for improvement prioritized by the committee included paper use, plastic use, and recycling.</p><p><strong>Conclusions: </strong>The pharmacy environmental audit tool described here can facilitate reflection on current practice, benchmarking, and goal setting. Pharmacy professionals have a role in leading change for the benefit of planetary health.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3591"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous IV Deferoxamine for Chronic Iron Overload in Patients Undergoing Hemodialysis by Home Parenteral Therapy: A Case Report and Literature Review.","authors":"Huisun Lau, Eddie Huang, Caitlin Olatunbosun","doi":"10.4212/cjhp.3577","DOIUrl":"10.4212/cjhp.3577","url":null,"abstract":"","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3577"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glycemic Management in Patients with COVID-19 Admitted to the Intensive Care Unit: Evaluation of Glycemic Control and Drug Therapy.","authors":"Emily Blacklaws, Kieran Shah, Sarah N Stabler","doi":"10.4212/cjhp.3553","DOIUrl":"10.4212/cjhp.3553","url":null,"abstract":"<p><strong>Background: </strong>Emerging evidence describes the high incidence and strong impact of hyperglycemia on the outcomes of critically ill patients with a diagnosis of COVID-19. Given resource limitations during the COVID-19 pandemic, clinicians moved away from using continuous IV infusions of insulin to manage hyperglycemia.</p><p><strong>Objective: </strong>To evaluate glycemic control in critically ill patients receiving various medication regimens to manage their hyperglycemia.</p><p><strong>Methods: </strong>This retrospective cohort study involved 120 mechanically ventilated adult patients (> 18 years) with COVID-19 who were admitted to the intensive care unit (ICU) between February 2020 and December 2021. The following data were collected for the first 14 days of the ICU admission: blood glucose values (up to 4 times daily), hypoglycemia events, and antihyperglycemic medication regimens.</p><p><strong>Results: </strong>The use of IV insulin infusions maintained glucose measurements within the target range of 4 to 10 mmol/L more often than any other medication regimen, with 60% of measured values falling within the target range. The use of a sliding-scale insulin regimen maintained 52% of glucose measurements within the target range. Oral hypoglycemic agents performed relatively poorly, with only 12% to 29% of glucose measurements within range. The coadministration of corticosteroids led to worse glycemic control across all medication regimens.</p><p><strong>Conclusions: </strong>This study confirmed that ICUs should continue using the standard protocol of IV insulin infusion to achieve recommended blood glucose targets in critically ill patients with COVID-19, particularly those receiving corticosteroids.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3553"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Drug Reactions and Predictors of Medication Adherence in Patients with Prostate Cancer.","authors":"Chinonyerem O Iheanacho, Valentine U Odili","doi":"10.4212/cjhp.3567","DOIUrl":"10.4212/cjhp.3567","url":null,"abstract":"<p><strong>Background: </strong>Adherence to therapy with prostate cancer medicines is critical for delaying the progression of disease and enhancing health outcomes.</p><p><strong>Objectives: </strong>To determine patients' medication adherence, the predictors of adherence, and the frequency and types of adverse drug reactions (ADRs) in persons with prostate cancer.</p><p><strong>Methods: </strong>A serial entry-point cross-sectional study of patients with prostate cancer was conducted in 3 cancer hospitals in Nigeria over a 12-month period (January 7, 2022, to January 3, 2023). Data on medication adherence were self-reported by patients, and data on ADRs were obtained from hospital records. Descriptive and inferential statistical analyses were performed, and <i>p</i> less than 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Of the 133 study participants, most 112 (84.2%) reported high medication adherence. The cost of drugs was the most frequently reported potential barrier to adherence (<i>n</i> = 63, 47.4%). Adherence was significantly dependent on family history of cancer (df = 3, <i>F</i> = 4.557, <i>p</i> = 0.005) and health-related quality of life (HRQOL) (ß = 0.275, <i>T</i> = 2.170, <i>p</i> = 0.032) but not illness perception (ß = 0.046, <i>T</i> = 0.360, <i>p</i> = 0.72). Adverse events were observed in 36 participants (27.1%) and were deemed to be \"possible ADRs\" (<i>n</i> = 19, 53%) or \"probable ADRs\" (<i>n</i> = 17, 47%); all were nonpreventable and expected (100%), and most (<i>n</i> = 31, 86%) were within the level 1 category of severity. Loss of erection and low libido was the most frequently reported ADR (<i>n</i> = 14, 39%).</p><p><strong>Conclusions: </strong>In this study, medication adherence was high, with cost being a potential barrier to adherence. Family history of cancer and HRQOL significantly predicted medication adherence. The medications were well tolerated, and observed ADRs had minor severity. Policies targeting the reduction of cost-related factors for prostate cancer medications are essential.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3567"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacité de 6 scénarios de décontamination de bras de fauteuils contaminés volontairement au cyclophosphamide.","authors":"Mathilde Dupré, Manon Marc, Jean-François Bussières","doi":"10.4212/cjhp.3588","DOIUrl":"10.4212/cjhp.3588","url":null,"abstract":"<p><strong>Background: </strong>The arms of chairs in outpatient oncology clinics are frequently contaminated with cyclophosphamide.</p><p><strong>Objective: </strong>To evaluate the effectiveness of decontamination scenarios.</p><p><strong>Methods: </strong>This was a descriptive simulation-type study of 6 decontamination scenarios of a silicone fabric surface contaminated with 10 μg of cyclophosphamide. The decontamination products tested (quaternary ammonium, 0.5% hydrogen peroxide, 0.005% detergent, and sodium hypochlorite 0.5%) were applied with microfibre wipes. Residual contamination was measured using an ultra-performance liquid chromatography-tandem mass spectrometry system with identical cyclophosphamide detection and quantification limits (0.0006 ng/cm²).</p><p><strong>Results: </strong>Among the 59 samples, 3 blanks were negative, 5 allowed measurement of the recovery rate (93.7% [standard deviation 4.6%]), and 51 were experimental. The average efficiency of the agents was greater than or equal to 99.79%. Regardless of the agent used, effectiveness was 99.30% (SD 1.20%) after 1 cleanse (<i>n</i> = 18), 99.90% (SD 0.15%) after 2 cleanses (<i>n</i> = 18), and 99.95% (SD 0.06%) after 3 cleanses (<i>n</i> = 15).</p><p><strong>Conclusion: </strong>The 6 decontamination scenarios were effective. Repeated cleaning marginally increased the effectiveness of decontamination.</p>","PeriodicalId":94225,"journal":{"name":"The Canadian journal of hospital pharmacy","volume":"77 4","pages":"e3588"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}