The American journal of the medical sciences最新文献_第2页

The bamboo ceiling: An underrecognized barrier for Asians and Asian Americans in academic medicine. 竹天花板：亚洲人和亚裔美国人在学术医学中未被充分认识的障碍。

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-16 DOI: 10.1016/j.amjms.2025.09.013

So Hyun Jeon, Anson O'Young, Ho-Man Yeung

引用次数: 0

Changes in perceived neighborhood environments by COVID-19: A nationwide Korean survey. 新冠肺炎对邻里环境感知的变化——韩国全国调查。

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-16 DOI: 10.1016/j.amjms.2025.09.008

Ki Dong Ko, In Cheol Hwang, Hong Yup Ahn

引用次数: 0

Association of Gustave Roussy immune score and the risk of in-hospital mortality in patients with acute respiratory distress syndrome: A retrospective cohort study from MIMIC-IV database. 急性呼吸窘迫综合征患者Gustave Roussy免疫评分与住院死亡风险的关联：来自MIMIC-IV数据库的回顾性队列研究

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-16 DOI: 10.1016/j.amjms.2025.09.011

Qiong Ji, Wei Liu

{"title":"Association of Gustave Roussy immune score and the risk of in-hospital mortality in patients with acute respiratory distress syndrome: A retrospective cohort study from MIMIC-IV database.","authors":"Qiong Ji, Wei Liu","doi":"10.1016/j.amjms.2025.09.011","DOIUrl":"10.1016/j.amjms.2025.09.011","url":null,"abstract":"Background: There has been a lack of studies to describe the relationship between Gustave Roussy immune score (GRIm-s) and the risk of in-hospital mortality in patients with acute respiratory distress syndrome (ARDS) so far. This study aimed to investigate the relationship between GRIm-s and hospital mortality in patients with ARDS and to compare the predictive ability of GRIm-s with common scoring systems for predicting mortality risk based on MIMIC-IV database.Methods: GRIm-s was calculated based on albumin, neutrophil-to-lymphocyte ratio (NLR) and lactate dehydrogenase (LDH). The univariate and multivariate logistic regression analysis were used to explore association between GRIm-s and in-hospital mortality, with odds ratio (OR) and 95 % confidence intervals (CIs). The receiver operator characteristic (ROC) analysis was performed to verity the predictive power and the enhancement the predictive power of GRIm-s to NLR and sequential organ failure assessment (SOFA), simplified acute physiology score II (SAPSII) and confusion, uremia, respiratory rate, blood pressure, age ≥65 years (CURB-65), with area under the curve (AUC) and 95 %CI.Results: Totally 1238 eligible ARDS patients were included with the in-hospital mortality was 34.25 %. High GRIm-s was associated with higher risk of in-hospital mortality. The predictive value of GRIm-s was superior to NLR. GRIm-s can significantly improve the predictive power of a single score prediction system including SOFA, SAPSII, and CURB-65.Conclusions: High GRIm-s was associated with high risk of in-hospital mortality in ARDS patients. GRIm-s has a good predictive ability for the prognosis of ARDS patients.","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-hospital isolated coronary artery bypass grafting outcomes in patients with psoriasis: a population-based National Inpatient Sample study from 2015-2021. 银屑病患者院内孤立冠状动脉旁路移植术的预后：2015-2021年基于人群的全国住院患者样本研究

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-16 DOI: 10.1016/j.amjms.2025.09.010

Renxi Li, SeungEun Lee, Deyanira J Prastein, Stephen J Huddleston

{"title":"In-hospital isolated coronary artery bypass grafting outcomes in patients with psoriasis: a population-based National Inpatient Sample study from 2015-2021.","authors":"Renxi Li, SeungEun Lee, Deyanira J Prastein, Stephen J Huddleston","doi":"10.1016/j.amjms.2025.09.010","DOIUrl":"10.1016/j.amjms.2025.09.010","url":null,"abstract":"Background: Psoriasis is a chronic skin disease that shares common inflammatory pathways with atherosclerosis. Although psoriasis is known to increase risk of developing coronary artery disease, the impact of psoriasis on outcomes after coronary artery bypass grafting (CABG) remains less established. This study aimed to compare the in-hospital outcomes of isolated CABG between patients with and without psoriasis through a population-based analysis of a national database.Methods: Patients underwent CABG were selected from National Inpatient Sample from Q4 2015-2021. Patients with age <18 years and concomitant procedures were excluded. A 1:2 propensity-score matching was used to match demographics, socioeconomic status, primary payer status, hospital characteristics, comorbidities, and transfer/admission status between psoriasis and non-psoriasis patients. In-hospital outcomes were assessed.Results: There were 1,732 (0.95%) patients who underwent isolated CABG who had psoriasis. Patients with psoriasis were younger and more socioeconomically advantaged. After propensity-score matched to 3598 out of 191,175 non-psoriasis patients, patients with and without psoriasis had comparable in-hospital mortality rates (1.39% vs 1.03%, p = 0.27) and major adverse cardiovascular event (1.45% vs 1.86%, p = 0.31). Psoriasis patients had a slightly lower risk of venous thromboembolism (0.23% vs 0.67%, p = 0.04). All other in-hospital outcomes were comparable between psoriasis and non-psoriasis patients.Conclusions: The representation of psoriasis patients in CABG was lower than their prevalence in the general population. After propensity-score matching, outcomes for patients with and without psoriasis were comparable. Thus, despite the elevated cardiovascular risks associated with psoriasis, CABG may be as safe and as effective for these patients.","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mortality trends for bacterial septicaemia in the United States (1999-2024): Age, sex disparities and the impact of the COVID-19 pandemic. 美国细菌性败血症死亡率趋势（1999-2024）：年龄、性别差异和COVID-19大流行的影响

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-16 DOI: 10.1016/j.amjms.2025.09.012

Camilla Mattiuzzi, Giuseppe Lippi

{"title":"Mortality trends for bacterial septicaemia in the United States (1999-2024): Age, sex disparities and the impact of the COVID-19 pandemic.","authors":"Camilla Mattiuzzi, Giuseppe Lippi","doi":"10.1016/j.amjms.2025.09.012","DOIUrl":"10.1016/j.amjms.2025.09.012","url":null,"abstract":"Background: Sepsis remains a significant public health challenge, with persistent mortality rates despite advancements in diagnosis and treatment. This study examined mortality trends for bacterial septicaemia in the US between 1999-2024.Methods: Mortality data were obtained from the National Center for Health Statistics, National Vital Statistics System, Provisional Mortality WONDER Online Database. Bacterial septicaemia-related deaths were identified using ICD-10 codes, and Poisson regression analysis was performed to assess trends across demographics.Results: Mortality for bacterial septicaemia declined from 1999 to 2012, showing a modest increase until 2019. A sharp rise occurred during the COVID-19 pandemic (2020-2022), with total deaths for bacterial septicaemia increasing by 21.2 % compared to the pre-pandemic period (17.4 % in females and 23.9 % in males). Mortality rates in males were consistently higher than in females throughout the study period. Poisson regression analysis did not reveal statistically significant long-term cumulative or sex-specific trends. Age-stratified analysis showed a sustained decline in mortality over time among children under 15 years, whereas mortality increased in adults in all age groups between 25 and 74 years. Age-stratified analysis excluding the early pandemic years showed a relative decline in mortality for bacterial septicaemia in those aged <1 to 24 years, a relative increase in the 45-74-year age group, and a stable trend in other age categories.Conclusions: Although cumulative mortality for bacterial septicaemia remained stable in the long term, rising deaths in middle-aged adults and pandemic-related increases highlight the need for reinforced prevention, timely diagnosis and accurate management strategies.","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A multiple sclerosis review for the primary care physician. 初级保健医生多发性硬化症综述。

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-11 DOI: 10.1016/j.amjms.2025.09.007

William Meador, Helena Steen

引用次数: 0

In untreated non-diabetic subjects, obesity is accompanied by greater associations of blood viscosity with glucose and oxidative metabolism. 在未经治疗的非糖尿病受试者中，肥胖伴随着血液粘度与葡萄糖和氧化代谢的更大关联。

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-09 DOI: 10.1016/j.amjms.2025.09.006

Fumihiro Tomoda, Hiroko Kurosaki, Hiroko Sugimori, Tsutomu Koike, Maiko Ohara, Atsumi Nitta, Koichiro Kinugawa

{"title":"In untreated non-diabetic subjects, obesity is accompanied by greater associations of blood viscosity with glucose and oxidative metabolism.","authors":"Fumihiro Tomoda, Hiroko Kurosaki, Hiroko Sugimori, Tsutomu Koike, Maiko Ohara, Atsumi Nitta, Koichiro Kinugawa","doi":"10.1016/j.amjms.2025.09.006","DOIUrl":"10.1016/j.amjms.2025.09.006","url":null,"abstract":"Background: The influences of blood viscosity on metabolism and the peripheral circulation have not been fully explored in obesity. We evaluated the impact of obesity on the associations of blood viscosity with those two systems in non-diabetic subjects.Methods: In 119 obese and 163 non-obese non-diabetic subjects, blood viscosity was measured using a falling-ball microviscometer. Homeostasis model assessment of insulin resistance (HOMA-IR) and blood lactate were also determined as indices for insulin resistance and anaerobic metabolism, respectively.Results: Blood viscosity was significantly greater in the obese group than in the non-obese group (4.25±0.46 versus 4.14±0.44 mPa·S, p = 0.032). Blood viscosity was independently positively associated with log HOMA-IR and log blood lactate in the obese group, but not in the non-obese group. In all subjects, the body mass index status (i.e., non-obese or obese = 0 or 1) × blood viscosity interaction was significantly associated with log HOMA-IR and log blood lactate (partial r = 0.130, p = 0.029 and partial r = 0.173, p = 0.013). Thus, greater influences of blood viscosity on glucose and oxidative metabolism were observed in the obese group than the non-obese group. However, only approximately 9 to 11 % of the variance in blood viscosity was attributable to differences in log HOMA-IR or log blood lactate in the obese group. Contrastingly, blood viscosity did not relate with blood pressure in either group.Conclusions: In non-diabetic obesity, blood viscosity elevates, and such hemorheological change could at least partially contribute to the aggravations of insulin resistance and anaerobic metabolism.","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How often is multifocal atrial tachycardia mistaken for atrial fibrillation in the emergency department? 多灶性房性心动过速在急诊科误诊为房颤的频率有多高？

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-05 DOI: 10.1016/j.amjms.2025.09.003

Yuval Avidan, Amir Aker, Razi Khoury, Baruch Weizman, Sameer Kassem

引用次数: 0

Vagus nerve stimulation as a novel therapeutic approach for musculoskeletal diseases. 迷走神经刺激作为一种治疗肌肉骨骼疾病的新方法。

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-04 DOI: 10.1016/j.amjms.2025.09.005

Shivmurat Yadav, Stavros Stavrakis, Constance R Chu, Mary Beth Humphrey

引用次数: 0

The risk of gastrointestinal bleeding with dual antiplatelet therapy in cirrhotics undergoing liver transplant evaluation. 肝硬化肝移植术后双重抗血小板治疗消化道出血的风险评估。

IF 1.8

The American journal of the medical sciences Pub Date : 2025-09-04 DOI: 10.1016/j.amjms.2025.09.001

Mark Cromer, Kaitlyn Domning, Rebecca Sullivan, Mahmoud Aryan, Erin Petrie, Sujan Ravi, Mark Beasley, Mohamed Shoreibah

{"title":"The risk of gastrointestinal bleeding with dual antiplatelet therapy in cirrhotics undergoing liver transplant evaluation.","authors":"Mark Cromer, Kaitlyn Domning, Rebecca Sullivan, Mahmoud Aryan, Erin Petrie, Sujan Ravi, Mark Beasley, Mohamed Shoreibah","doi":"10.1016/j.amjms.2025.09.001","DOIUrl":"10.1016/j.amjms.2025.09.001","url":null,"abstract":"Background: Metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis is now the second leading indication for liver transplantation (LT) worldwide and is associated with increased risk of cardiovascular events before and after LT. Cirrhotics who undergo left heart catheterization (LHC) with coronary artery stenting for LT evaluation require dual antiplatelet therapy (DAPT). Data regarding the safety, risk of gastrointestinal (GI) bleeding, and mortality risk of cirrhotics receiving DAPT is limited.Aim: The objective of this study was to assess the risk of and outcomes related to GI bleeding in cirrhotics undergoing LT evaluation who received DAPT.Methods: We conducted a retrospective review of adults with decompensated cirrhosis who underwent a LHC as part of LT evaluation between 2014 and 2021.Results: A total of 291 patients were included. Thirty-three underwent LHC with coronary artery stenting and received DAPT, while 258 underwent LHC without intervention and received no DAPT. When comparing the DAPT and control groups, there were no significant differences in the following: GI bleeding on univariate analysis (9.09% vs 14.73%; p= 0.381) and multivariate analysis (odds ratio = 0.579; 95% confidence interval = 0.168 - 1.992; p = 0.386); recurrent GI bleeding (0% vs 4.26%; p = 0.227); variceal hemorrhage (3.03% vs 4.65%; p = 0.671); liver transplanation (30.30% vs 44.19%; p = 0.129); or 12-month mortality following GI bleeding (3.03% vs 5.81%; p = 0.509).Conclusions: Use of DAPT was not associated with an increased risk of GI bleeding or bleeding-related complications in decompensated cirrhotics with coronary artery disease undergoing LT evaluation.","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0