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Light Therapy Modalities in the Management of Acne. 痤疮治疗中的光疗模式。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Sarah Friske, Tejas P Joshi, Jaime Tschen
{"title":"Light Therapy Modalities in the Management of Acne.","authors":"Sarah Friske, Tejas P Joshi, Jaime Tschen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Much like the update in the classification of the acne commensal from <i>Propionibacterium acnes (P. acnes)</i> to <i>Cutibacterium acnes (C. acnes)</i>, the treatment of acne has observed advances, augmenting topical and oral medications, including anti-microbial peptides, chemical peels, microencapsulated medications, and probiotics. The traditional paradigm of acne treatment has its limitations, such as skin irritation, photosensitivity, concern over antibiotic resistance, and regimen complexity. Given these challenges, discussing alternative options for acne treatment in detail is important. Light therapy, in particular, is an emerging modality that has transformed the landscape of acne management and thus merits additional discussion (Table 1).</p>","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CABTREOTM (Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide) Topical Gel. CABTREOTM（克林霉素磷酸酯、阿达帕林和过氧化苯甲酰）外用凝胶。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Aditya K Gupta, Avantika Mann, Kimberly Vincent, William Abramovits
{"title":"CABTREO<sup>TM</sup> (Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide) Topical Gel.","authors":"Aditya K Gupta, Avantika Mann, Kimberly Vincent, William Abramovits","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cabtreo<sup>TM</sup> (1.2% clindamycin phosphate, 0.15% adapalene, and 3.1% benzoyl peroxide) or IDP-126 topical gel was approved by the US Food and Drug Administration (FDA) in October 2023 for the treatment of moderate to severe acne vulgaris in patients aged ≥12 years. Its effectiveness and safety were evaluated in two phase 3 trials (Trial 1 and Trial 2). In both trials, subjects were randomized into two groups, one received IDP-126 gel and the other received vehicle gel. The primary efficacy end point was treatment success at week 12, defined as subjects achieving at least a 2-grade reduction from baseline in Evaluator's Global Severity Score (EGGS) and a final score ranging from 0 (clear) to 1 (almost clear) as well as reduced counts of inflammatory and non-inflammatory lesions. In Trial 1 (N = 183), treatment success was achieved in 49.6% (61/122) of subjects in the IDP-126 group versus 24.9% (15/61) of subjects in the vehicle group (<i>P</i> < 0.01). In Trial 2 (N = 180), treatment success was achieved in 50.5% (61/120) of subjects in the IDP-126 group versus 20.5% (12/60) of subjects in the vehicle group (<i>P</i> < 0.01). IDP-126 is therefore recommended to be applied as a thin layer to the affected area once daily.</p>","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short Anagen Syndrome. 短促青春期综合征
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Jonathan Young, Michaela Mifsud, Liam Mercieca
{"title":"Short Anagen Syndrome.","authors":"Jonathan Young, Michaela Mifsud, Liam Mercieca","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 10-year-old healthy, Caucasian girl presented in May 2021 with short and thin scalp hair since birth (Figures 1A-C). She had achieved all of her developmental milestones, and her parents denied any similar family history. She had only two hair cuts in the past, which were performed to trim long hair over the midscalp to have a uniform length. Hair at the front, back, and sides of the scalp were never trimmed. Examination revealed short, dark, and thin hair, varying in length from a few millimeters to 2 cm, over the frontal, parietal, and occipital areas. Longer hair were present over the midscalp, varying in length from 5 cm to 8 cm. The hairpull test was negative, and dermatoscopic examination of short hair demonstrated tapered ends, rather than cut ends. Microscopic examination revealed no hair shaft abnormality, and a trichogram of 50 parietal hair fibers demonstrated an anagen versus telogen ratio of 68:32. No associated skin, dental, or nail abnormalities were discovered.</p>","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound Aspect of a New Hybrid Soft-Tissue Filler Combining Hyaluronic Acid and Calcium Hydroxyapatite. 一种新型混合软组织填充剂（玻尿酸与羟基磷灰石钙）的超声特性
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Mariana Calomeni Elias, Thamires Silva Cavalcante de Almeida, Bruna Souza Felix Bravo
{"title":"Ultrasound Aspect of a New Hybrid Soft-Tissue Filler Combining Hyaluronic Acid and Calcium Hydroxyapatite.","authors":"Mariana Calomeni Elias, Thamires Silva Cavalcante de Almeida, Bruna Souza Felix Bravo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lowell A. Goldsmith, MD, MPH (March 29, 1938-July 10, 2024). 洛厄尔-戈德史密斯（Lowell A. Goldsmith），医学博士，公共卫生硕士（1938 年 3 月 29 日-2024 年 7 月 10 日）。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Anthony A Gaspari
{"title":"Lowell A. Goldsmith, MD, MPH (March 29, 1938-July 10, 2024).","authors":"Anthony A Gaspari","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyclosporine-Iinduced Glycosuria. 环孢素诱发糖尿。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Heng Li Wei, Ho Sheun Ling Madeline, Yew Yik Weng
{"title":"Cyclosporine-Iinduced Glycosuria.","authors":"Heng Li Wei, Ho Sheun Ling Madeline, Yew Yik Weng","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our first patient was a 42-year-old healthy Chinese man with moderately severe psoriasis, not adequately controlled with potent topical steroids and vitamin D analogs. His pre-immunosuppressant work-up was normal. He was prescribed methotrexate prior to switching to cyclosporine with an initial dose of 200 mg daily (2.44 mg/kg/day). His urinalysis was normal 2 months after initiating cyclosporine. After 18 months of cyclosporine therapy, his urinalysis revealed glycosuria (300 mg/dL), even though his fasting serum glucose was 5.2 mmol/L (normal) and there was no indication of any urinary tract infection (UTI). This occurred at a dose of 100 mg every 2 days (0.610 mg/kg/day). The glycosuria resolved on the next check, and he was shifted to adalimumab.</p>","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acrodermatitis Continua of Hallopeau Evolving into Psoriatic Monoarthritis: Successfully Treated with Apremilast. 哈洛坡续发性银屑病演变为银屑病单关节炎：使用阿普司特治疗成功。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Tampouratzi Eleftheria, Giagkou Eirini-Nektaria, Katsantonis Ioannis, Douvali Theodora
{"title":"Acrodermatitis Continua of Hallopeau Evolving into Psoriatic Monoarthritis: Successfully Treated with Apremilast.","authors":"Tampouratzi Eleftheria, Giagkou Eirini-Nektaria, Katsantonis Ioannis, Douvali Theodora","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermatopathology Rotation and Education for Residents: The Art and Science of Traditional and Innovative Pedagogic Methods. 皮肤病理学轮转和住院医师教育：传统与创新教学方法的艺术与科学》。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Muhammad N Mahmood
{"title":"Dermatopathology Rotation and Education for Residents: The Art and Science of Traditional and Innovative Pedagogic Methods.","authors":"Muhammad N Mahmood","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Proficiency in dermatopathology is important for comprehending the mechanisms of skin diseases and determining efficacious clinical management. Dermatopathology learning is a core requirement for both dermatology and pathology residencies. Many traditional educational methods have been utilized over decades for teaching our residents. In the recent digitized era, technological advances are impacting the study and practice of medicine. Several innovative tools have become available that complement the conventional learning model. This contribution provides guidelines for establishing a robust dermatopathology rotation for residents and insights into the present and future advances in novel educational tools. Dermatopathology is an ever-growing body of knowledge. It takes years to accumulate practical knowledge of this discipline and requires a continuing effort to maintain and keep it updated. This journey of learning starts during the early years of postgraduate medical education. Attaining competency in dermatopathology is vital for both dermatology and pathology residents. The earlier the exposure they receive, the better the foundation and understanding of cutaneous disease processes they develop. Comprehensive training in the subspecialty of dermatopathology is critical for their medical education and the future practice.</p>","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predatory Conferences and Journals in Dermatology Are Black Widow Parties. 皮肤病学的掠夺性会议和期刊是黑寡妇派对。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Dedee F Murrell, Jeffrey M Weinberg, Paul S Yamauchi, Ayman Abdelmaksoud, Stephan Grabbe, Mohamad Goldust
{"title":"Predatory Conferences and Journals in Dermatology Are Black Widow Parties.","authors":"Dedee F Murrell, Jeffrey M Weinberg, Paul S Yamauchi, Ayman Abdelmaksoud, Stephan Grabbe, Mohamad Goldust","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Racial Disparities in Inpatient Consult Services: A Retrospective Analysis. 住院病人咨询服务中的种族差异：回顾性分析。
Skinmed Pub Date : 2024-10-22 eCollection Date: 2024-01-01
Alexander Sherban, Elizabeth Critchlow, Annyella Douglas, Matthew Keller
{"title":"Racial Disparities in Inpatient Consult Services: A Retrospective Analysis.","authors":"Alexander Sherban, Elizabeth Critchlow, Annyella Douglas, Matthew Keller","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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