RadiologiaPub Date : 2025-03-01DOI: 10.1016/j.rxeng.2023.09.010
L. Graña-López, L. Abelairas-López, A. Villares
{"title":"Cryoablation in breast tumours","authors":"L. Graña-López, L. Abelairas-López, A. Villares","doi":"10.1016/j.rxeng.2023.09.010","DOIUrl":"10.1016/j.rxeng.2023.09.010","url":null,"abstract":"<div><div>Cryoablation is a percutaneous thermal ablation technique developed to destroy focal groups of cells using extreme cold. It is an outpatient and image-guided procedure, performed under local anaesthesia, with typically short recovery times and good outcomes. Percutaneous cryoablation has good success rates for treating breast fibroadenomas. It is used in cases of malignant tumours mainly when a patient refuses surgery or is not considered to be a suitable candidate. Some studies indicate that cryoablation could be as effective and safe as lumpectomy in cases of low-risk early-stage breast cancer. Moreover, some studies have reported a regression of metastatic foci after ablation of a primary tumour thanks to an anti-tumour immune response stimulated by cryoablation. This article describes the technique and its indications with regards to breast tumours according to the existing literature.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 2","pages":"Pages 214-222"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-03-01DOI: 10.1016/j.rxeng.2023.06.005
S. Marsico , I. Carrión Barberà , A. Agustí Claramunt , J. Monfort Faure , J.M. Maiques Llácer , T.C. Salman Monte , A. Solano López
{"title":"Shear wave elastosonography applied to synovitis: A preliminary study","authors":"S. Marsico , I. Carrión Barberà , A. Agustí Claramunt , J. Monfort Faure , J.M. Maiques Llácer , T.C. Salman Monte , A. Solano López","doi":"10.1016/j.rxeng.2023.06.005","DOIUrl":"10.1016/j.rxeng.2023.06.005","url":null,"abstract":"<div><h3>Aim</h3><div>This study aims to evaluate the utility of shear wave elastography<span> (SWE) in identifying synovitis in patients with a history of arthritis within the diagnosis of a defined rheumatological disease.</span></div></div><div><h3>Materials and methods</h3><div>We performed B-mode and SWE (ultrasound) on 58 participants divided into two groups: group 1 included 29 patients with confirmed active wrist and/or hand synovitis; group 2 included 29 healthy volunteers without suspicion of synovitis. In a subset of patients (n<!--> <!-->=<!--> <span>8), joint counts and disease evaluations were performed during the elastography<span> to study the correlation between clinical and radiological findings.</span></span></div></div><div><h3>Results</h3><div>The mean maximum kPa value and the average joint kPa value were significantly different between cases and controls: maximum kPa value for cases was 38.14<!--> <!-->±<!--> <!-->35.08<!--> <!-->kPa, while for controls it was 4.72<!--> <!-->±<!--> <!-->5.93<!--> <!-->kPa; average joint value for cases was 29.77<!--> <!-->±<!--> <!-->26.07<!--> <!-->kPa, while for controls it was 4.17<!--> <!-->±<!--> <span>5.22. The most frequent location for joint effusion in both, cases and controls, was the dorsal radiocarpal joint: 41.4% of controls had a mean kPa value of 7.66</span> <!-->±<!--> <!-->5.39<!--> <!-->kPa, while 58.6% of cases had a mean kPa value of 40.61<!--> <!-->±<!--> <!-->40.76<!--> <!-->kPa (p-value 0.004). kPa values correlated with disease activity measurements in the 8 patients clinically evaluated at the moment of the SWE.</div></div><div><h3>Conclusions</h3><div>SWE is a promising technique that may have a role in the diagnosis and assessment of synovial inflammatory activity in arthritis.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 2","pages":"Pages 115-127"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138623438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-03-01DOI: 10.1016/j.rxeng.2025.02.001
V. Pai , C. Parra-Fariñas , F. Shaikh , A. Mallipatna , C. Zaarour , P. Muthusami
{"title":"An updated review of intra-arterial chemotherapy for retinoblastoma","authors":"V. Pai , C. Parra-Fariñas , F. Shaikh , A. Mallipatna , C. Zaarour , P. Muthusami","doi":"10.1016/j.rxeng.2025.02.001","DOIUrl":"10.1016/j.rxeng.2025.02.001","url":null,"abstract":"<div><div>Retinoblastoma (RB) is the most common pediatric ocular malignancy and causes high mortality if left untreated. An accurate diagnosis and prompt treatment are of utmost importance, leading to optimal clinical outcomes. RB treatment has evolved over the years with a paradigm shift from life-saving enucleation to globe- and vision-sparing strategies. Intra-arterial chemotherapy (IAC) has become an essential and effective pillar in the management of RB. It has gained popularity as it is a targeted chemotherapeutic agent infusion technique achieved via superselective ophthalmic artery (OA) catheterisation. This improves tumour treatment and reduces recurrence and systemic side effects. In addition, it is often performed as an outpatient procedure, reducing the need for prolonged hospital stays and improving the overall patient experience. In this review, we discuss the history of IAC as well as its technical evolution, outcomes, potential complications and limitations.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 2","pages":"Pages 162-175"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-03-01DOI: 10.1016/j.rxeng.2024.04.006
A. Aguado del Hoyo, M. Sánchez Pérez, M. Vázquez López, L. Vara de Andrés, Á. Lancharro Zapata, Y. Ruiz Martín
{"title":"Neuroinmunological diseases in paediatric patients: New entities and update","authors":"A. Aguado del Hoyo, M. Sánchez Pérez, M. Vázquez López, L. Vara de Andrés, Á. Lancharro Zapata, Y. Ruiz Martín","doi":"10.1016/j.rxeng.2024.04.006","DOIUrl":"10.1016/j.rxeng.2024.04.006","url":null,"abstract":"<div><div>Neuroinmunological diseases are a broad heterogeneous group of inflammatory disorders in which damage to the central nervous system occurs as a result of immune system abnormalities that can be caused by various pathogenic mechanisms. This may be produced by the presence of autoantibodies, mediated by cells, triggered by infections and paraneoplastic processes, or have a genetic cause.</div><div>Radiologists should be familiar with these diseases and be able to perform a differential diagnosis, as early diagnosis and appropriate treatment with immunotherapy can modify the course of the disease in some cases.</div><div>This update has two objectives:</div><div>Review the most common entities within each group, including demyelinating diseases, autoimmune encephalitis, lupus erythematosus, Rasmussen's encephalitis, and haemophagocytic lymphohistiocytosis.</div><div>Describe key imaging features that aid in the differential diagnosis between different entities.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 2","pages":"Pages 176-190"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-01-01DOI: 10.1016/j.rxeng.2023.09.007
F.D. Choque-Chávez , A. Jareño-Badenas , D. Benítez-Ribas , L. Oleaga
{"title":"Evaluation of central nervous system involvement in patients undergoing chimeric antigen receptor-engineered T-cell therapy by magnetic resonance imaging","authors":"F.D. Choque-Chávez , A. Jareño-Badenas , D. Benítez-Ribas , L. Oleaga","doi":"10.1016/j.rxeng.2023.09.007","DOIUrl":"10.1016/j.rxeng.2023.09.007","url":null,"abstract":"<div><div><span>Chimeric antigen receptor-engineered (CAR) T-cell therapy is an effective immunotherapy for aggressive hematologic cancers. However, it can lead to complications such as immune effector cell-associated </span>neurotoxicity syndrome<span><span> (ICANS), or complications related to the immunosuppressive status of these patients. The role of imaging in this context is essential to help in ICANS diagnosis and to rule out other potential diagnosis, such as </span>central nervous system infections. Two cases are presented to illustrate this clinical problem.</span></div></div><div><h3>Case 1</h3><div><span><span><span>describes a 38-year-old patient with diffuse large B-cell lymphoma who developed ICANS after CAR T-cell therapy. MRI revealed signs of </span>leukoencephalopathy. Case 2 involves a 57-year-old patient with mantle-cell lymphoma who presented </span>neurologic symptoms -clinically suggestive of ICANS- after CAR-T therapy. MRI showed signs indicative of </span>limbic encephalitis.</div><div>These two cases highlight the importance of MRI in clinical practice after CAR T-Cell Therapy underscoring the role of MRI in the diagnosis of complications in patients with neuropsychiatric symptoms.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 1","pages":"Pages 91-95"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139296148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-01-01DOI: 10.1016/j.rxeng.2023.05.005
A. Gomes Lima Junior , M.F. Lucena Karbage , P.A. Nascimento
{"title":"Update on ethical aspects in clinical research: Addressing concerns in the development of new AI tools in radiology","authors":"A. Gomes Lima Junior , M.F. Lucena Karbage , P.A. Nascimento","doi":"10.1016/j.rxeng.2023.05.005","DOIUrl":"10.1016/j.rxeng.2023.05.005","url":null,"abstract":"<div><div>The analysis of ethical aspects in clinical research has always been a challenge and has required constant updates.</div><div>In short, research ethics is the set of specific principles, rules, and norms of behavior that a research community has decided are appropriate and fair under the premise that research must be valid, reliable, legitimate, and representative.</div><div>This non-systematic review brings some ethical concerns that should be considered within the scientific community. Many studies and the development of new artificial intelligence (AI) tools, especially in radiology, make it necessary for the radiology research community to promote debates and establish ethical standards for the practice and development of new AI tools.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 1","pages":"Pages 85-90"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-01-01DOI: 10.1016/j.rxeng.2024.01.007
A. Ezponda , F.M. Caballeros Lam , G. Bastarrika Alemañ
{"title":"CT myocardial perfusion and FFR-CT for the assessment of coronary artery disease","authors":"A. Ezponda , F.M. Caballeros Lam , G. Bastarrika Alemañ","doi":"10.1016/j.rxeng.2024.01.007","DOIUrl":"10.1016/j.rxeng.2024.01.007","url":null,"abstract":"<div><div>CT coronary angiography is the most reliable non-invasive imaging technique for ruling out coronary artery disease. However, its specificity is not high. Thus, when coronary stenosis of uncertain functional significance is detected, the recommendation is to perform complementary imaging tests to assess myocardial ischemia. CT myocardial perfusion imaging and CT fractional flow reserve provide added diagnostic accuracy and prognostic value to CT coronary angiography, by increasing its predictive value and facilitating therapeutic decision-making.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 1","pages":"Pages 101-112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RadiologiaPub Date : 2025-01-01DOI: 10.1016/j.rxeng.2023.03.010
S. Groff , G. Barbiero , M. Battistel , A.C. Frigo , G. De Conti
{"title":"Effect of transarterial embolization of iatrogenic renal artery pseudoaneurysms without or with arteriovenous fistula on renal function at 6-month follow-up","authors":"S. Groff , G. Barbiero , M. Battistel , A.C. Frigo , G. De Conti","doi":"10.1016/j.rxeng.2023.03.010","DOIUrl":"10.1016/j.rxeng.2023.03.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Transarterial embolization (TAE) is the gold standard treatment for iatrogenic renal artery pseudoaneurysms (PSA) and pseudoaneurysms with arteriovenous fistula (PSA + AVF), but its impact on renal function has not been sufficiently investigated. The aim of the study is to assess the impact on of TAE on renal function and its technical and clinical effectiveness.</div></div><div><h3>Materials and methods</h3><div>Sixty-seven embolization procedures in 61 consecutive patients from December 2006 to October 2020 in two centers were retrospectively reviewed for the following parameters: technical and clinical success and failure, embolization materials, type and dimensions of vascular injuries, percentage of post-procedural ischemic renal parenchyma and estimated glomerular filtration rate (eGFR) values before and 1 day after the surgical, percutaneous or endoscopic (SPE) procedure and before, 1 day after and 6 months after TAE.</div></div><div><h3>Results</h3><div>We identified 44 PSA and 23 PSA + AVF. Technical success was 95.5%, primary clinical success was 90.2% and secondary clinical success was 96.7%. Different embolization materials were used. A significant decrease of the eGFR was found after the SPE procedure. No significant difference was found between eGFR before and after TAE. A minimal significant improvement of the eGFR was found 6 months after TAE. Embolization of larger lesions resulted in larger post-procedural ischemic areas. PSA + AVF were significantly larger (p = 0.0142) and determined a larger post-procedural ischemic area. No correlation was found between dimensions, kind of vascular injury or post-procedural ischemic area and eGFR.</div></div><div><h3>Conclusion</h3><div>TAE has high technical and clinical success rates and does not affect renal function negatively, regardless of dimensions or kind of vascular injuries or post-procedural ischemic area.</div></div>","PeriodicalId":94185,"journal":{"name":"Radiologia","volume":"67 1","pages":"Pages 3-16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}