Postgraduate medicine最新文献

筛选
英文 中文
Evaluation of the use of telemedicine in pediatric intensive care units: a cluster-randomized trial. 儿科重症监护室使用远程医疗的评估:分组随机试验。
Postgraduate medicine Pub Date : 2024-08-01 Epub Date: 2024-08-05 DOI: 10.1080/00325481.2024.2388023
Gabriela de Oliveira Laguna Silva, Emanuele König Klever, Jacqueline Castro da Rocha, Mariana Motta Dias da Silva, Jerusa da Rosa de Amorim, Vanessa Cristina Jacovas, Bárbara Marina Simionato, Luciane Gomes da Cunha, Ana Paula Berni Zaupa, João Ronaldo Mafalda Krauzer, Aristóteles de Almeida Pires, Felipe Cezar Cabral, Taís de Campos Moreira, Hilda Maria Rodrigues Moleda Constant
{"title":"Evaluation of the use of telemedicine in pediatric intensive care units: a cluster-randomized trial.","authors":"Gabriela de Oliveira Laguna Silva, Emanuele König Klever, Jacqueline Castro da Rocha, Mariana Motta Dias da Silva, Jerusa da Rosa de Amorim, Vanessa Cristina Jacovas, Bárbara Marina Simionato, Luciane Gomes da Cunha, Ana Paula Berni Zaupa, João Ronaldo Mafalda Krauzer, Aristóteles de Almeida Pires, Felipe Cezar Cabral, Taís de Campos Moreira, Hilda Maria Rodrigues Moleda Constant","doi":"10.1080/00325481.2024.2388023","DOIUrl":"10.1080/00325481.2024.2388023","url":null,"abstract":"<p><strong>Introduction: </strong>Telemedicine has shown promising results, allowing specialists to provide rapid and effective care in remote locations. However, to our knowledge, current evidence is not robust enough to prove the effectiveness of this tool. This cluster-randomized trial (CRT) aimed to evaluate the impact of telemedicine on clinical care indicators in pediatric intensive care units (PICUs).</p><p><strong>Methods: </strong>An open-label CRT was conducted in 16 PICUs within the Brazilian public health system. The trial took place from August 2022 to December 2023 and compared an intervention group, which received telemedicine support, with a control group, which received usual PICU care. The primary outcome was the PICU length of stay. The main secondary outcomes were mortality rate and ventilator-free days.</p><p><strong>Results: </strong>A total of 1393 participants were included, 657 in the control group and 736 in the intervention group. The mean PICU length of stay was 10.42 (SD, 10.71) days for the control group and 11.52 (SD, 10.80) days for the intervention group. The overall mean of ventilator-free days was 6.82 (SD, 7.71) days. Regarding mortality, 7.54% of participants died in total. No significant difference was found in the outcomes between the groups.</p><p><strong>Conclusion: </strong>Despite the potential benefits of telemedicine, its effective implementation in the Brazilian public health system faces considerable challenges, highlighting the continued importance of investigating and improving the role of telemedicine in pediatric critical care.</p><p><strong>Clinical trial registration: </strong>ClinicalTrials.gov NCT05260710 and ReBEC - RBR-7×j4wyp.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"633-640"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Legionella maceachernii pneumonia: a case report and literature review. 军团菌麦氏肺炎:病例报告和文献综述。
Postgraduate medicine Pub Date : 2024-08-01 Epub Date: 2024-07-31 DOI: 10.1080/00325481.2024.2385888
Gaofeng Pan, Maoying Fu, Huihui Ni, Wei Zhang, Yi Yao, Yingcong Xie, Jing Li, Yijia Zhang, Yuting Wang, Kexing Han, Yufeng Gao
{"title":"<i>Legionella maceachernii</i> pneumonia: a case report and literature review.","authors":"Gaofeng Pan, Maoying Fu, Huihui Ni, Wei Zhang, Yi Yao, Yingcong Xie, Jing Li, Yijia Zhang, Yuting Wang, Kexing Han, Yufeng Gao","doi":"10.1080/00325481.2024.2385888","DOIUrl":"10.1080/00325481.2024.2385888","url":null,"abstract":"<p><strong>Background: </strong>Legionella maceachernii pneumonia is a severe respiratory infection with low incidence but high mortality. However, the optimal treatment for this disease remains unclear. We report a case of successful treatment of Legionella maceachernii pneumonia, which is the first report of such a case in China.</p><p><strong>Case presentation: </strong>An 87-year-old man with concomitant chronic obstructive pulmonary disease, liver cirrhosis, and history of left nephrectomy was diagnosed with Legionella maceachernii pneumonia using Dano-seq pathogen metagenomic testing. After two weeks of treatment with cefoperazone/sulbactam combined with quinolone antibiotics, the patient showed improvement and was discharged. The patient continued to take oral quinolone antibiotics for one week after discharge and recovered during outpatient follow-up.</p><p><strong>Conclusions: </strong>Dano-seq pathogen metagenomic testing can rapidly diagnose Legionella maceachernii pneumonia, and taking quinolone antibiotics is an effective treatment.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"678-682"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the current situation and trend of home-based individualized nursing for residents in a certain area in China. 中国某地区居民居家个性化护理现状及趋势分析 "互联网+护理服务 "的认知与需求。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-28 DOI: 10.1080/00325481.2024.2370233
Yu-Qin Ren, Li Wang, Yan Gu, Yu-Fei Qian, Dan-Feng Li, San-Lian Zhou
{"title":"Analysis of the current situation and trend of home-based individualized nursing for residents in a certain area in China.","authors":"Yu-Qin Ren, Li Wang, Yan Gu, Yu-Fei Qian, Dan-Feng Li, San-Lian Zhou","doi":"10.1080/00325481.2024.2370233","DOIUrl":"10.1080/00325481.2024.2370233","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to examine the perception, willingness to engage, and demand of community residents regarding the 'internet + nursing service' in a designated pilot area, aiming to offer insights for the widespread adoption of the 'internet + nursing service' throughout China.</p><p><strong>Methods: </strong>A survey pertaining to the 'internet + nursing service' was conducted from March to April 2022. The study specifically targeted residents within two sub-districts of a city in the Jiangsu province. The sampling technique employed in this study was stratified random sampling.</p><p><strong>Results: </strong>Out of a total of 400 community residents selected from two sub-districts in this region, 378 provided valid responses, resulting in an effective rate of 94.5%. Within the study cohort, 80 participants (21.16%) demonstrated familiarity with the concept of 'internet + nursing service.' Additionally, 231 participants (61.11%) conveyed their willingness to adopt such services. Regarding service preferences, the primary demands were for health guidance, vital sign monitoring, and basic care. Challenges in implementing the service were attributed to concerns related to medical risks, personal safety for both nurses and patients, and potential breaches of privacy.</p><p><strong>Conclusions: </strong>Residents in the pilot area exhibited a moderate awareness of the 'internet + nursing service,' with a relatively high willingness to embrace the program. There is a need for further refinement of pertinent laws, widespread dissemination of policies, and enhancements in the quality of nursing services. These measures aim to ensure that a greater number of community residents can avail themselves of improved home-based nursing services.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"551-561"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Controlling Nutritional Status (CONUT) score is a novel marker of type 2 diabetes mellitus and diabetic microvascular complications. 控制营养状况(CONUT)评分是 2 型糖尿病和糖尿病微血管并发症的新型标记。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-28 DOI: 10.1080/00325481.2024.2373684
Gulali Aktas, Tuba Taslamacioglu Duman, Burcin Atak Tel
{"title":"Controlling Nutritional Status (CONUT) score is a novel marker of type 2 diabetes mellitus and diabetic microvascular complications.","authors":"Gulali Aktas, Tuba Taslamacioglu Duman, Burcin Atak Tel","doi":"10.1080/00325481.2024.2373684","DOIUrl":"10.1080/00325481.2024.2373684","url":null,"abstract":"<p><strong>Objectives: </strong>Type 2 diabetes mellitus (T2DM) and its microvascular complications are characterized by chronic inflammation. The Controlling Nutritional Status (CONUT) score is a tool used to assess nutritional status and is often associated indirectly with inflammatory processes. We aimed to compare the CONUT scores of T2DM patients with those of healthy volunteers and to compare T2DM patients with and without microvascular complications.</p><p><strong>Methods: </strong>Patients diagnosed with T2DM and healthy volunteers (as controls) were included in the study. The CONUT score is calculated using the following formula: serum albumin score + total cholesterol score + total lymphocyte count score. CONUT scores of T2DM patients and healthy controls, as well as those of diabetics with and without microvascular complications, were compared.</p><p><strong>Results: </strong>The CONUT scores of the T2DM and control groups were (1 [0-7]) and (0 [0-2]), respectively (<i>p</i> < 0.001). The sensitivity and specificity of the CONUT score (<1.5 threshold) in detecting T2DM were 43% and 90%, respectively (AUC: 0.67, <i>p</i> < 0.001, 95% CI: 0.64-0.71). Moreover, the CONUT score was an independent risk factor for T2DM (OR: 0.34, <i>p</i> < 0.001, 95% CI: 0.22-0.52). The CONUT score of T2DM patients with microvascular complications (2 [0-7]) was significantly higher than that of T2DM patients without microvascular complications (0 [0-4]) and control subjects (0 [0-2]) (<i>p</i> < 0.001). A CONUT score higher than 1.5 had 83% sensitivity and 92% specificity in detecting T2DM with microvascular complications (AUC: 0.91, <i>p</i> < 0.001, 95% CI: 0.89-0.93).</p><p><strong>Conclusion: </strong>The CONUT score could be useful in detecting diabetic microvascular complications in clinical practice, as it is an inexpensive and easy-to-assess marker.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"496-503"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141452549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immersive teaching using virtual reality technology to improve ophthalmic surgical skills for medical postgraduate students. 利用虚拟现实技术开展沉浸式教学,提高医学研究生的眼科手术技能。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-06 DOI: 10.1080/00325481.2024.2363171
Ning Wang, Shuo Yang, Qi Gao, Xiuming Jin
{"title":"Immersive teaching using virtual reality technology to improve ophthalmic surgical skills for medical postgraduate students.","authors":"Ning Wang, Shuo Yang, Qi Gao, Xiuming Jin","doi":"10.1080/00325481.2024.2363171","DOIUrl":"10.1080/00325481.2024.2363171","url":null,"abstract":"<p><p>Medical education is primarily based on practical schooling and the accumulation of experience and skills, which is important for the growth and development of young ophthalmic surgeons. However, present learning and refresher methods are constrained by several factors. Nevertheless, virtual reality (VR) technology has considerably contributed to medical training worldwide, providing convenient and practical auxiliary value for the selection of students' sub-majors. Moreover, it offers previously inaccessible surgical step training, scenario simulations, and immersive evaluation exams. This paper outlines the current applications of VR immersive teaching methods for ophthalmic surgery interns.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"487-495"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying malnutrition risk in hospitalized patients: an analysis of five tools in the light of GLIM criteria. 识别住院病人的营养不良风险:根据 GLIM 标准对五种工具进行分析。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-04 DOI: 10.1080/00325481.2024.2363169
Sedat Arslan, Nursel Dal, Kevser Tari Selcuk, Kezban Sahin, Ramazan Mert Atan
{"title":"Identifying malnutrition risk in hospitalized patients: an analysis of five tools in the light of GLIM criteria.","authors":"Sedat Arslan, Nursel Dal, Kevser Tari Selcuk, Kezban Sahin, Ramazan Mert Atan","doi":"10.1080/00325481.2024.2363169","DOIUrl":"10.1080/00325481.2024.2363169","url":null,"abstract":"<p><strong>Background: </strong>The prompt identification of malnutrition among hospitalized patients using the appropriate screening tool is paramount. The objective of our study is to compare the most recommended screening tools concerning the new GLIM criteria for malnutrition in hospitalized patients.</p><p><strong>Methods: </strong>In this cross-sectional study, we analyzed the data on 1,397 patients receiving inpatient treatment at Bandırma Training and Research Hospital between August 2022 and May 2023 to assess and compare malnutrition in them. Patients who received inpatient treatment in the internal and surgical clinics of Bandırma Training and Research Hospital. In addition to the GLIM criteria, we used nutritional screening and assessment tools such as NRS-2002, MST, GMS, MUST, and SNAQ. The GLIM criteria were considered the gold standard for the evaluation of sensitivity and specificity. Receiver operating characteristic (ROC) curves for the five screening tools were also used to assess the ability to distinguish malnutrition-risk patients accurately.</p><p><strong>Results: </strong>The comparison of the performances of different screening tools in detecting malnutrition demonstrated that while the GMS had the highest sensitivity (87.40%), the NRS-2002 had the highest specificity (91.70%). The area under the Curve (AUC) value indicated that the predictive values of the NRS-2002, MST, GMS, and SNAQ were excellent, and the predictive value of the MUST was good (<i>p</i> < 0.001). While the GLIM criteria in particular appear to be an effective tool for detecting malnutrition in hospitalized individuals, other screening tools are also useful in assessing their malnutrition risk.</p><p><strong>Conclusions: </strong>We emphasized MST's alignment with GLIM criteria, underscoring the importance of a multidisciplinary approach for early malnutrition diagnosis. Patients at risk of malnutrition can be diagnosed more quickly and accurately with appropriate screening tools and the effectiveness of treatments can be increased.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"504-513"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low free T3 level may predict the severity of acute pancreatitis. 低游离 T3 水平可预测急性胰腺炎的严重程度。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-24 DOI: 10.1080/00325481.2024.2370238
Başak Can, Esra Deniz Kahvecioğlu
{"title":"Low free T3 level may predict the severity of acute pancreatitis.","authors":"Başak Can, Esra Deniz Kahvecioğlu","doi":"10.1080/00325481.2024.2370238","DOIUrl":"10.1080/00325481.2024.2370238","url":null,"abstract":"<p><strong>Objectives: </strong>To demonstrate that deterioration in thyroid function tests can serve as an indicator of severity and prognosis in acute pancreatitis despite a healthy thyroid gland.</p><p><strong>Methods: </strong>This study is a retrospective, single-center study. Patients diagnosed with acute pancreatitis between May 2020 and June 2021 were evaluated. Acute pancreatitis was diagnosed and classified according to the 2012 revised Atlanta criteria. Patients were categorized into Non-Thyroidal Illness Syndrome and euthyroid groups and compared in terms of biochemical parameters and scoring systems such as Ranson, Glasgow, Balthazar and BISAP scores.</p><p><strong>Results: </strong>A total of 152 patients were included in the study. Eighty-three patients (54%) were euthyroid, with free triiodothyronine (T3), free thyroxine (T4), and Thyroid-stimulating hormone (TSH) levels within normal limits. Sixty-nine patients (46%) had Non-Thyroidal Illness Syndrome with low serum free T3 levels and low/normal TSH levels. As expected, free T3 was significantly lower in the Non-Thyroidal Illness Syndrome group than in the euthyroid group (1.5 ± 0.04 vs 2.6 ± 0.04, respectively, <i>p</i> < 0.0001). In the Non-Thyroidal Illness Syndrome group, Ranson score (3.35 ± 0.2 vs 2.11 ± 0.18 <i>p</i> < 0.0001), Glasgow (2.4 ± 0.2 vs 1.3 ± 0.1, <i>p</i> < 0.0001), Atlanta (<i>p</i> = 0.007), and Balthazar (2.1 ± 0.1 vs 1.4 ± 0.1, <i>p</i> = 0.001) scores were significantly higher than euthyroid group.</p><p><strong>Conclusion: </strong>Non-Thyroidal Illness Syndrome provides insight into the prognosis of acute pancreatitis. Free T3 values are a significant parameter that may indicate the prognosis of acute pancreatitis. We believe that free T3 could be incorporated into an ideal scoring system in a disease such as acute pancreatitis, where early determination of prognosis is known to significantly reduce mortality.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"562-566"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of two ablation procedures combined with high ligation and foam sclerotherapy and compression therapy for patients with venous leg ulcers. 对腿部静脉溃疡患者进行两种消融术联合高位结扎和泡沫硬化剂疗法及压力疗法的比较。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-13 DOI: 10.1080/00325481.2024.2366155
Guofu Zheng, Hailiang Xie, Minggui Lai, Bao Qin, Xiaochun Liu
{"title":"Comparison of two ablation procedures combined with high ligation and foam sclerotherapy and compression therapy for patients with venous leg ulcers.","authors":"Guofu Zheng, Hailiang Xie, Minggui Lai, Bao Qin, Xiaochun Liu","doi":"10.1080/00325481.2024.2366155","DOIUrl":"10.1080/00325481.2024.2366155","url":null,"abstract":"<p><strong>Aim: </strong>To compare the ablation techniques' efficacy of endovenous microwave ablation (EMA) combined with high ligation (HL), foam sclerotherapy (FS) and compression therapy (CT) and endovenous laser ablation (EVLA) combined with HL-FS-CT in the treatment of VLUs.</p><p><strong>Method: </strong>301 consecutive patients with VLUs from 2013 to 2022 in a 3200-bed hospital were intervened by EMA combined with HL-FS-CT and EVLA combined with HL-FS-CT were retrospectively compared.</p><p><strong>Results: </strong>One hundred thirty-four patients underwent EMA+HL-FS-CT and 167 patients underwent EVLA+HL-FS-CT. The primary outcome of the ulcer healing time was 1.45(0.75-1.5) months and 1.86(0.5-2.5) months, respectively, in the two groups (HR for ulcer healing was 1.26, 95% CI [0.96-1.66], <i>p</i> = 0.097). Secondary outcomes included that no significant difference was found in ulcer recurrence and GSV recanalization and complications between the two groups, and the postoperative VCSS and AVVQ were significantly lower than the baseline values in the respective groups (<i>p</i> = 0.0001).</p><p><strong>Conclusion: </strong>EMA+HL-FS-CT and EVLA+HL-FS-CT are both effective at treating VLUs. Both of the two comprehensive treatments were beneficial to the healing of ulcers, but no evidence showed which one was superior in the ulcer healing time.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"514-522"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are all ADHD medications created equal? Exploring the differences that enable evening dosing. 所有多动症药物都一样吗?探究晚间用药的差异。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-26 DOI: 10.1080/00325481.2024.2370230
Gregory W Mattingly, Julie A Carbray, Perry Roy, Frank A López
{"title":"Are all ADHD medications created equal? Exploring the differences that enable evening dosing.","authors":"Gregory W Mattingly, Julie A Carbray, Perry Roy, Frank A López","doi":"10.1080/00325481.2024.2370230","DOIUrl":"10.1080/00325481.2024.2370230","url":null,"abstract":"<p><p>With more than 30 available stimulant medications, choosing among therapeutic options for attention-deficit/hyperactivity disorder (ADHD) has become increasingly complex and patient specific. All ADHD stimulants owe their action to variants of either amphetamine or methylphenidate, yet formulation and delivery system differences create unique pharmacokinetic and clinical profiles for each medication. A benefit of the diversity within ADHD pharmacotherapy is that it facilitates tailoring treatment to meet patient needs. Historically, there has been a constant among long-acting stimulant options, regardless of formulation, which was morning dosing. The introduction of delayed-release and extended-release methylphenidate (DR/ER-MPH) is the first long-acting stimulant that patients take in the evening, with the clinical effect delayed until awakening in the morning. This paradigm shift has generated questions among clinicians and continued interest in real-world experience and data. This review used available clinical data, real-world evidence, emerging analyses, and clinical experience to evaluate the characteristics of DR/ER-MPH and its clinical utility within the greater context of ADHD medications and to provide clinicians with practical guidance on the use of DR/ER-MPH in children, adolescents, and adults with ADHD.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"475-486"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wearable monitoring device based on an internet management platform improves metabolic parameters in type 2 diabetes patients: a prospective pilot study. 基于互联网管理平台的可穿戴监测设备可改善 2 型糖尿病患者的代谢参数:一项前瞻性试点研究。
Postgraduate medicine Pub Date : 2024-06-01 Epub Date: 2024-06-13 DOI: 10.1080/00325481.2024.2366156
Ping Peng, Yunfeng Shen, Haixia Xiong
{"title":"Wearable monitoring device based on an internet management platform improves metabolic parameters in type 2 diabetes patients: a prospective pilot study.","authors":"Ping Peng, Yunfeng Shen, Haixia Xiong","doi":"10.1080/00325481.2024.2366156","DOIUrl":"10.1080/00325481.2024.2366156","url":null,"abstract":"<p><strong>Objectives: </strong>This pilot study aimed to prospectively investigate the effects of a wearable monitoring device, based on an Internet management platform, on the comprehensive management of type 2 diabetes mellitus (T2DM) patients.</p><p><strong>Methods: </strong>A total of 120 hospitalized patients with T2DM were enrolled and randomly divided into the control group and the intervention group. Patients in the control group only received conventional diabetes treatments, while patients in the intervention group were provided with a wearable monitoring device in addition to conventional diabetes treatments. Moreover, the wearable device could connect to an Internet platform for diabetes management and upload self-monitoring data. All patients were followed for 3 months. The changes in parameters representing glucose metabolism, blood lipids, renal function, and patient satisfaction were compared between the two groups. All results were analyzed on an intention-to-treat basis.</p><p><strong>Results: </strong>One hundred twenty subjects met all criteria and agreed to participate in this study. During the follow-up period, 5 and 4 subjects were lost to follow-up in the intervention and control groups, respectively. Compared with the control group, the blood glucose of the intervention group decreased significantly after 3 months (<i>p</i> < 0.05). Subgroup analysis found that females, those younger than 60 years, with baseline glycated hemoglobin A1c (HbA1c) levels of 8% or greater, and patients with good adherence showed significant improvements in HbA1c (<i>p</i> < 0.05). However, there was no significant difference in blood lipid and renal function. The intervention group showed a better adherence rate to blood glucose, comprehensive adherence rate, and diabetes treatment satisfaction (<i>p</i> < 0.05). One subject in the intervention group and two subjects in the control group reported mild hypoglycemia. No other adverse events such as infections and skin allergies occurred in the two groups.</p><p><strong>Conclusion: </strong>The intervention of a wearable monitoring device based on an Internet management platform significantly improved blood glucose control in T2DM patients, as well as the overall adherence rate and patient satisfaction with treatment.</p><p><strong>Clinical trial registration: </strong>NCT04973644.</p>","PeriodicalId":94176,"journal":{"name":"Postgraduate medicine","volume":" ","pages":"523-532"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141319410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信