Modern rheumatology case reports最新文献_第9页

Paediatric Cogan Syndrome masquerading as IgA vasculitis. 儿童Cogan综合征伪装成IgA血管炎。

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad060

Praveen K Ramani, Florin Grigorian, Heidi Lightle, Saumya V Joshi

{"title":"Paediatric Cogan Syndrome masquerading as IgA vasculitis.","authors":"Praveen K Ramani, Florin Grigorian, Heidi Lightle, Saumya V Joshi","doi":"10.1093/mrcr/rxad060","DOIUrl":"10.1093/mrcr/rxad060","url":null,"abstract":"Paediatric Cogan Syndrome is a rare and underrecognised autoimmune vasculitis characterised by ocular inflammation and sensorineural hearing loss. Its etiopathogenesis, diagnosis, and management are not well defined. We report a 12-year-old girl who initially presented with symptoms of IgA vasculitis formerly called Henoch Schoenlein Purpura (HSP) and eventually developed anterior uveitis and bilateral sensorineural hearing loss leading to the diagnosis of atypical Cogan Syndrome. The workup for infectious etiologies and other systemic rheumatologic disorders was negative. The management was multidisciplinary involving Rheumatology, Ophthalmology, Otorhinolaryngology, and Audiology. The anterior uveitis responded well to systemic glucocorticoids and Methotrexate, but the hearing loss was grossly progressive warranting a cochlear implant. We are not aware of Paediatric Cogan Syndrome being reported as a mimicker of IgA vasculitis previously in the literature. It is an important finding as IgA vasculitis is prevalent in the paediatric age group and new-onset ocular or vestibular symptoms after IgA vasculitis should alert the clinician to the possibility of Cogan Syndrome. In the absence of well-defined diagnostic criteria, it is crucial to recognise the clinical symptoms of Paediatric Cogan Syndrome for early diagnosis and treatment since the delay in diagnosis can lead to permanent disability.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71416413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of dupilumab combination therapy for exacerbation of atopic dermatitis in a patient with eosinophilic granulomatosis with polyangiitis treated with mepolizumab. 一例特应性皮炎加重，患者为嗜酸性粒细胞增多症伴多血管炎，用Mepolizumab治疗，并用Dupilumab联合治疗成功。

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad059

Yosuke Iwadate, Yoshiyuki Arinuma, Yu Matsueda, Tomoki Tanaka, Tatuhiko Wada, Sumiaki Tanaka, Kenji Oku, Kunihiro Yamaoka

引用次数: 0

A case of atypical IgG4-related disease presenting hypereosinophilia, polyneuropathy, and liver dysfunction. 一例非典型IgG4相关疾病，表现为嗜酸性粒细胞增多、多发性神经病和肝功能障碍。

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad053

Hiroki Mukoyama, Kosaku Murakami, Hideo Onizawa, Mirei Shirakashi, Ryosuke Hiwa, Hideaki Tsuji, Koji Kitagori, Shuji Akizuki, Ran Nakashima, Akira Onishi, Hajime Yoshifuji, Masao Tanaka, Akio Morinobu

引用次数: 0

Total knee arthroplasty for neuropathic arthropathy in a patient with leprosy. 全膝关节置换术治疗麻风患者的神经性关节病。

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad057

Sakumo Kii, Motoki Sonohata, Masaaki Mawatari

{"title":"Total knee arthroplasty for neuropathic arthropathy in a patient with leprosy.","authors":"Sakumo Kii, Motoki Sonohata, Masaaki Mawatari","doi":"10.1093/mrcr/rxad057","DOIUrl":"10.1093/mrcr/rxad057","url":null,"abstract":"Patients with leprosy are known to tend to develop neuropathic arthropathy, known as Charcot joint. There are no case reports of total knee arthroplasty (TKA) in patients with leprosy with polyarticular neuropathic arthropathy, and the results are unknown. In this study, we report a case of TKA in a patient with leprosy with polyarticular neuropathic arthropathy and discuss its outcomes and indications. Right TKA using the NexGen Legacy Constrained Condylar Knee implant was performed in a 62-year-old man with neuropathic arthropathy in multiple joints with clinical symptoms, particularly in the right knee. Seven years post-operation, the American Knee Society Score-knee and -function, which represent knee function and activities of daily living on a scale of 100 points, were significantly improved compared with preoperative values, from 30 to 99 points and 0 to 60 points, respectively. Indications for arthroplasty for neuropathic arthropathy should be carefully considered in each individual case. In this case, the patient had neuropathic arthropathy in multiple joints; however, TKA was performed because recovery of function in the right knee was expected to significantly improve the patient's activities of daily living, and a good mid-term clinical outcome was achieved. Therefore, indications for arthroplasty should be considered in patients with systemic neuropathic arthropathy such as leprosy, and with accurate assessment and appropriate implant selection, good long-term outcomes may be expected.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overlapping systemic lupus erythematosus, seropositive erosive rheumatoid arthritis, and ANCA-associated vasculitis: A case report and literature review. 重叠型系统性红斑狼疮、血清阳性侵蚀性类风湿性关节炎和ANCA相关血管炎的病例报告和文献综述。

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad056

Emma Reesor, Sankalp Virendrakumar Bhavsar

{"title":"Overlapping systemic lupus erythematosus, seropositive erosive rheumatoid arthritis, and ANCA-associated vasculitis: A case report and literature review.","authors":"Emma Reesor, Sankalp Virendrakumar Bhavsar","doi":"10.1093/mrcr/rxad056","DOIUrl":"10.1093/mrcr/rxad056","url":null,"abstract":"The overlap of rheumatoid arthritis and systemic lupus erythematosus is well described, with a syndrome known as 'rhupus'. ANCA-associated vasculitis, however, is uncommonly associated with other autoimmune conditions. Here, we present a case of lupus, rheumatoid arthritis, and ANCA-associated vasculitis, with significant time elapsed between presentations, resulting in an accumulation of the three diagnoses over the course of 35 years. The patient was diagnosed with lupus at age 45, presenting with inflammatory polyarthritis, thrombocytopenia, leukopenia, positive ANA, positive anti-DNA, and hypocomplementemia. She was maintained on hydroxychloroquine therapy with minimal disease activity. Approximately 20 years later, she had a flare of polyarthritis with bilateral wrist erosive arthropathy and a positive rheumatoid factor, diagnosed as rheumatoid arthritis. Anti-TNFα therapy was initiated, and she was stable for a further 10 years. At age 79, she developed ANCA-associated vasculitis AAV with pulmonary and renal manifestations, treated with rituximab induction therapy and steroids. She recovered and her MPO-ANCA titre normalised. One year later, off the anti-TNFα, she again experienced an acute kidney injury with a repeat rise in MPO-ANCA. She was re-induced and maintained on steroids and rituximab. This novel case highlights the range of possible overlap syndromes, as well as how multiple autoimmune diagnoses can evolve over decades in previously stable disease. There is growing work around polyautoimmunity with ANCA-associated vasculitis and other systemic autoimmune diseases, which has potential to identify common aetiologies and pathogenesis. Knowledge of these overlap syndromes can help to recognise and manage these conditions in a timely manner.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41177708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Arthritis after vaccination against SARS-CoV-2 infection: Reactive arthritis or post-vaccination arthritis? 接种严重急性呼吸系统综合征冠状病毒2型疫苗后的关节炎：反应性关节炎还是接种后关节炎？

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad058

Chokan Baimukhamedov, Galina Veklenko, Gaziza Smagulova

引用次数: 0

Nontuberculous mycobacteriosis oligoarthritis of the right hand misdiagnosed as rheumatoid arthritis: A case report. 非结核分枝杆菌病误诊为类风湿性关节炎的右手寡关节炎1例报告。

Modern rheumatology case reports Pub Date : 2023-12-29 DOI: 10.1093/mrcr/rxad052

Yuji Joyo, Sanshiro Yasuma, Takuya Usami, Yusuke Hattori, Yohei Noda, Sakurako Kato, Ryohei Kondo, Soichiro Watanabe, Yuko Waguri-Nagaya

引用次数: 0

Correction to: A case of atypical IgG4-related disease presenting hypereosinophilia, polyneuropathy, and liver dysfunction. 更正:1例非典型igg4相关疾病，表现为嗜酸性粒细胞增多、多发性神经病变和肝功能障碍。

Modern rheumatology case reports Pub Date : 2023-12-01 DOI: 10.1093/mrcr/rxad066

引用次数: 0