Modern rheumatology case reports最新文献_第2页

Kikuchi-Fujimoto Disease and primary Sjögren's Syndrome coexisting: a case-based literature review. 菊池-藤本氏病与原发性斯约格伦综合征并存：基于病例的文献综述。

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Modern rheumatology case reports Pub Date : 2024-09-21 DOI: 10.1093/mrcr/rxae058

Maria João Cadório, João Oliveira, João Gama, Cátia Duarte

{"title":"Kikuchi-Fujimoto Disease and primary Sjögren's Syndrome coexisting: a case-based literature review.","authors":"Maria João Cadório, João Oliveira, João Gama, Cátia Duarte","doi":"10.1093/mrcr/rxae058","DOIUrl":"https://doi.org/10.1093/mrcr/rxae058","url":null,"abstract":"Kikuchi-Fujimoto Disease (KFD), also known as Kikuchi histiocytic necrotizing lymphadenitis, is an extremely rare and benign condition that mostly affects young women. It is characterized by lymph node involvement with a predilection for the cervical region, commonly presenting with tender lymphadenopathy and a low-grade fever. The diagnosis requires excisional lymph node biopsy with immunohistochemical analysis. KFD is mostly self-limiting within a few weeks to months, with only some patients requiring symptomatic relief with NSAIDs or corticosteroids, and a minority developing recurrent episodes of the disease. Importantly, it has been reported in association with Systemic Lupus Erythematosus, and, to a lesser extent, other immune-mediated inflammatory rheumatic diseases, such as Sjögren's Syndrome, whose clinical presentation itself may include lymphadenopathy. In this paper, we present an unusual case of a woman with primary Sjögren Syndrome (pSS) and a past medical history relevant for lymphoma, sarcoidosis and thymoma, who later developed KFD, a particularly challenging diagnosis in this setting. We then performed a literature review of the association between KFD and pSS, gathering a total of 13 patients, and focusing epidemiological, clinical, and laboratory data.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tense blisters and hemorrhagic bullae as the first manifestation of eosinophilic granulomatosis with polyangiitis. 嗜酸性粒细胞肉芽肿伴多血管炎的首发症状--张力性水疱和出血性大疱。

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Modern rheumatology case reports Pub Date : 2024-09-16 DOI: 10.1093/mrcr/rxae056

Hajime Inokuchi, Mitsuhiro Akiyama, Hiroto Horikawa, Yasushi Kondo, Shuntaro Saito, Jun Kikuchi, Hironari Hanaoka, Yuko Kaneko

引用次数: 0

A case of eosinophilic granulomatosis with polyangiitis preceded by allergic bullous lesions. 一例嗜酸性粒细胞肉芽肿伴多血管炎病例，发病前出现过敏性大疱。

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Modern rheumatology case reports Pub Date : 2024-09-11 DOI: 10.1093/mrcr/rxae046

Eiko Hasegawa, Momoko Iijima, Akinari Sekine, Noriko Inoue, Kiho Tanaka, Tatsuya Suwabe, Masayuki Yamanouchi, Yuki Oba, Ayako Kume, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Yutaka Yamaguchi, Yasuhiro Suyama, Takehiko Wada, Naoki Sawa, Kotono Takahashi, Shigeharu Ueki, Yoshifumi Ubara

{"title":"A case of eosinophilic granulomatosis with polyangiitis preceded by allergic bullous lesions.","authors":"Eiko Hasegawa, Momoko Iijima, Akinari Sekine, Noriko Inoue, Kiho Tanaka, Tatsuya Suwabe, Masayuki Yamanouchi, Yuki Oba, Ayako Kume, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Yutaka Yamaguchi, Yasuhiro Suyama, Takehiko Wada, Naoki Sawa, Kotono Takahashi, Shigeharu Ueki, Yoshifumi Ubara","doi":"10.1093/mrcr/rxae046","DOIUrl":"https://doi.org/10.1093/mrcr/rxae046","url":null,"abstract":"A 62-year-old man with a history of diabetes mellitus was hospitalised with numbness of lower limbs, bullous lesions of the whole body, kidney dysfunction, presence of eosinophils, and elevated antineutrophil cytoplasmic antibodies to myeloperoxidase and anti-bullous pemphigoid 180 antibodies and was diagnosed with mononeuritis multiplex. Kidney and muscle biopsies showed vasculitis with fibrinoid necrosis, whereas skin biopsies showed only blister formation between the epidermis and dermis; a high eosinophilic infiltrate was present in all three tissues. These findings led to a diagnosis of eosinophilic granulomatosis with polyangiitis combined with allergic bullous lesions. Immunohistological examination indicated cytolytic eosinophils and extracellular traps, suggesting the presence of eosinophil extracellular trap cell death (eosinophil ETosis) in diseased tissue.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elderly-onset inflammatory myopathy associated with Sjögren's syndrome following SARS-CoV-2 vaccination. 接种 SARS-CoV-2 疫苗后，老年炎症性肌病与斯约格伦综合征相关。

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Modern rheumatology case reports Pub Date : 2024-09-11 DOI: 10.1093/mrcr/rxae055

Yuta Komori, Satomi Kobayashi, Keiko Hatano, Yuko Saito, Tomio Arai, Kanae Kubo

{"title":"Elderly-onset inflammatory myopathy associated with Sjögren's syndrome following SARS-CoV-2 vaccination.","authors":"Yuta Komori, Satomi Kobayashi, Keiko Hatano, Yuko Saito, Tomio Arai, Kanae Kubo","doi":"10.1093/mrcr/rxae055","DOIUrl":"https://doi.org/10.1093/mrcr/rxae055","url":null,"abstract":"As vaccination against SARS-CoV-2 has progressed, various autoimmune diseases, including inflammatory myopathies, have been reported to develop after vaccination. Sjögren's syndrome (SS) sometimes presents as extra-glandular manifestations including inflammatory myopathy. In this report, we describe a case of inflammatory myopathy associated with SS that occurred in an atypically elderly patient after receiving the first dose of the SARS-CoV-2 mRNA vaccine (BNT162b2). The inflammatory myopathy was pathologically classified into non-specific myositis and characterised by predominant infiltration of the B cell lineage in this case. Combined treatment with glucocorticoid, intravenous immunoglobulin, and immunosuppressant resulted in an improvement in swallowing function and muscle strength. While we recognise the efficacy and safety of SARS-CoV-2 vaccines, we also emphasise the importance of recognising that individuals with an immunogenetic predisposition such as positivity of anti SS-A antibody may show disease activity including inflammatory myopathy following vaccination in SS, even at an atypically old age.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Heart Failure with Reduced Ejection Fraction Following Ozoralizumab in A Patient with Rheumatoid Arthritis: A Case Report. 类风湿性关节炎患者使用奥唑来珠单抗后出现射血分数降低的急性心力衰竭：病例报告。

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Modern rheumatology case reports Pub Date : 2024-09-07 DOI: 10.1093/mrcr/rxae053

Takaaki Ito, Yuji Miyoshi

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A Japanese case of VEXAS syndrome after COVID-19 vaccination: Comparison with previously reported cases. 日本一例接种 COVID-19 疫苗后出现的 VEXAS 综合征：与先前报告病例的比较。

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Modern rheumatology case reports Pub Date : 2024-09-07 DOI: 10.1093/mrcr/rxae054

Yui Miyagi, Hiroshi Kobayashi, Yoshihiro Umebayashi, Akira Okimura, Munehide Nakatsugawa, Ayaka Maeda, Yohei Kirino, Akiko Aoki

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Induced membrane technique and intramedullary beaming for the extensive bone defect of the talonavicular joint: A case report and literature review. 诱导膜技术和髓内束治疗距骨关节广泛骨缺损：病例报告和文献综述。

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Modern rheumatology case reports Pub Date : 2024-09-05 DOI: 10.1093/mrcr/rxae048

Yuki Ohue, Kosho Togei, Hiroaki Shima, Yoshihiro Hirai, Ken Tanaka, Masashi Neo

引用次数: 0

Reply to the Letter from Suzuki K et al. 对 Suzuki K 等人来信的答复

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Modern rheumatology case reports Pub Date : 2024-09-02 DOI: 10.1093/mrcr/rxae052

Koto Hattori, Shigeru Tanaka, Hiroshi Nakajima

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Visceral disseminated varicella zoster virus infection masquerading as lupus mesenteric vasculitis recurrence. 伪装成狼疮肠系膜血管炎复发的内脏播散性水痘带状疱疹病毒感染。

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Modern rheumatology case reports Pub Date : 2024-09-02 DOI: 10.1093/mrcr/rxae051

Koji Suzuki, Mitsuhiro Akiyama, Yuko Kaneko

引用次数: 0

Epstein-Barr Virus-Encoded RNA-Positive Lymphocytes in Bone Marrow and Lymph Nodes in an Autopsy Case of TAFRO Syndrome. 一例 TAFRO 综合征尸检病例骨髓和淋巴结中的 Epstein-Barr 病毒编码 RNA 阳性淋巴细胞

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Modern rheumatology case reports Pub Date : 2024-08-24 DOI: 10.1093/mrcr/rxae049

Nao Tsugita, Ippei Miyagawa, Shingo Nakayamada, Aya Nawata, Shumpei Kosaka, Masanobu Ueno, Yoshiya Tanaka

{"title":"Epstein-Barr Virus-Encoded RNA-Positive Lymphocytes in Bone Marrow and Lymph Nodes in an Autopsy Case of TAFRO Syndrome.","authors":"Nao Tsugita, Ippei Miyagawa, Shingo Nakayamada, Aya Nawata, Shumpei Kosaka, Masanobu Ueno, Yoshiya Tanaka","doi":"10.1093/mrcr/rxae049","DOIUrl":"https://doi.org/10.1093/mrcr/rxae049","url":null,"abstract":"A 55-year-old man was admitted to the hospital with vomiting, diarrhoea, and chest pain. Upon examination, he exhibited signs of increased inflammatory response, acute kidney injury, and thrombocytopenia, leading to a diagnosis of TAFRO syndrome, which was supported by the clinical evidence of generalized lymphadenopathy, pleural effusion, and hepatosplenomegaly. Despite receiving intensive multimodal immunosuppressive therapy, including glucocorticoid pulse therapy (methylprednisolone 1,000 mg/day), tocilizumab, and cyclosporine in the intensive care unit, the patient showed minimal response and succumbed to the disease on the seventh day of hospitalization. Histopathological analysis of the lymph nodes revealed idiopathic multicentric Castleman disease (iMCD)-like features, and Epstein-Barr virus-encoded RNA (EBER) in situ hybridization identified multiple EBER-positive cells. These findings highlight the elusive pathogenic mechanism of TAFRO syndrome and the potential resistance of some patients to standard treatments such as tocilizumab. The presence of EBER-positive cells in lymph nodes or bone marrow may serve as an indicator of disease severity and treatment resistance. Therefore, histopathological detection of EBER-positive cells may help predict responsiveness to conventional treatments, disease severity, and prognosis in patients with TAFRO syndrome.","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0