Mental health science最新文献

{"title":"A Longitudinal Investigation of Mechanisms in the Mental and Physical Health Effects of Discrimination on Sexual Minority Women","authors":"Laura C. Wilson","doi":"10.1002/mhs2.70042","DOIUrl":"https://doi.org/10.1002/mhs2.70042","url":null,"abstract":"<p>Because the majority of existing literature examining mental health outcomes in sexual minority individuals has focused on men, the present study examined mechanisms in mental health disparities among sexual minority women. These analyses were based on the 200 sexual minority women (71.5% white) who completed an online survey at two time points, 6 months apart (August, 2024 and February, 2025). The online survey included measures of discrimination, group-specific processes, general psychological mechanisms, and mental and physical health. The indirect associations between discrimination and depression symptoms (<i>ab</i> = 0.06, 95% CI [0.012, 0.106]), PTSD symptoms (<i>ab</i> = 0.07, 95% CI [0.023, 0.131]) and physical health difficulties (<i>ab</i> = 0.04, 95% CI [0.007, 0.084]) via maladaptive coping were significant. The indirect association between discrimination and depression symptoms via adaptive coping was also significant (<i>ab</i> = <i>−</i>0.02, 95% CI [−0.050, −0.001]). No indirect associations were supported for group-specific mechanisms. The results are presented in the context of empirical and clinical implications.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147565074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Longitudinal Investigation of Mechanisms in the Mental and Physical Health Effects of Discrimination on Sexual Minority Women","authors":"Laura C. Wilson","doi":"10.1002/mhs2.70042","DOIUrl":"10.1002/mhs2.70042","url":null,"abstract":"<p>Because the majority of existing literature examining mental health outcomes in sexual minority individuals has focused on men, the present study examined mechanisms in mental health disparities among sexual minority women. These analyses were based on the 200 sexual minority women (71.5% white) who completed an online survey at two time points, 6 months apart (August, 2024 and February, 2025). The online survey included measures of discrimination, group-specific processes, general psychological mechanisms, and mental and physical health. The indirect associations between discrimination and depression symptoms (<i>ab</i> = 0.06, 95% CI [0.012, 0.106]), PTSD symptoms (<i>ab</i> = 0.07, 95% CI [0.023, 0.131]) and physical health difficulties (<i>ab</i> = 0.04, 95% CI [0.007, 0.084]) via maladaptive coping were significant. The indirect association between discrimination and depression symptoms via adaptive coping was also significant (<i>ab</i> = <i>−</i>0.02, 95% CI [−0.050, −0.001]). No indirect associations were supported for group-specific mechanisms. The results are presented in the context of empirical and clinical implications.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147565073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dementia and Mild Cognitive Impairment in Prison Care Pathway (DECISION): An Initial Programme Theory Informed by Umbrella Review and Participatory Co-Design Workshops","authors":"Deborah Buck,&nbsp;Adam O'Neill,&nbsp;Lee D. Mulligan,&nbsp;Stuart Ware,&nbsp;Jenny J. Shaw,&nbsp;Catherine Robinson,&nbsp;Charlotte Lennox,&nbsp;Louise Robinson,&nbsp;Jane Senior,&nbsp;Leanne Heathcote,&nbsp;Katrina Forsyth","doi":"10.1002/mhs2.70041","DOIUrl":"https://doi.org/10.1002/mhs2.70041","url":null,"abstract":"<p>In England and Wales, approximately 8% of prisoners aged 50 and over are likely to have dementia/MCI, but they do not receive equivalent care to their counterparts in the community. We previously designed DECISION (Dementia and Mild Cognitive Impairment in prison), a care pathway and training/awareness package for use in prison. The aim of this article is to describe the development of an initial programme theory (IPT) and logic model for the DECISION care pathway. Development of the IPT and logic model was an iterative process involving: i) an umbrella review approach to synthesising information from seven systematic reviews of dementia in prison; ii) co-design workshops with key stakeholders including experts by experience; and iii) reviewing our previous qualitative work. Key elements of the IPT and logic model include specialist training for and ongoing supervision of dementia care coordinators; ageing awareness training for all staff in prison; use of two cognitive screening tools; and release planning, including awareness-raising among probation and third sector groups who work with people released from prison who have dementia/MCI. The IPT and logic model will provide stakeholders with a proposed framework for the innovation or further development of dementia care and support in prison.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dementia and Mild Cognitive Impairment in Prison Care Pathway (DECISION): An Initial Programme Theory Informed by Umbrella Review and Participatory Co-Design Workshops","authors":"Deborah Buck,&nbsp;Adam O'Neill,&nbsp;Lee D. Mulligan,&nbsp;Stuart Ware,&nbsp;Jenny J. Shaw,&nbsp;Catherine Robinson,&nbsp;Charlotte Lennox,&nbsp;Louise Robinson,&nbsp;Jane Senior,&nbsp;Leanne Heathcote,&nbsp;Katrina Forsyth","doi":"10.1002/mhs2.70041","DOIUrl":"10.1002/mhs2.70041","url":null,"abstract":"<p>In England and Wales, approximately 8% of prisoners aged 50 and over are likely to have dementia/MCI, but they do not receive equivalent care to their counterparts in the community. We previously designed DECISION (Dementia and Mild Cognitive Impairment in prison), a care pathway and training/awareness package for use in prison. The aim of this article is to describe the development of an initial programme theory (IPT) and logic model for the DECISION care pathway. Development of the IPT and logic model was an iterative process involving: i) an umbrella review approach to synthesising information from seven systematic reviews of dementia in prison; ii) co-design workshops with key stakeholders including experts by experience; and iii) reviewing our previous qualitative work. Key elements of the IPT and logic model include specialist training for and ongoing supervision of dementia care coordinators; ageing awareness training for all staff in prison; use of two cognitive screening tools; and release planning, including awareness-raising among probation and third sector groups who work with people released from prison who have dementia/MCI. The IPT and logic model will provide stakeholders with a proposed framework for the innovation or further development of dementia care and support in prison.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adapting WHO's Step-By-Step Digital Intervention for Anxiety and Depression for Delivery Via Radio: Development, Piloting and Mixed-Methods Evaluation of the Lumuno Radio Campaign In Zambia","authors":"Abbie Clare,&nbsp;Rina Mukumba,&nbsp;Megan Mclaren,&nbsp;Naeem Dalal,&nbsp;Joanna Murray,&nbsp;Sonali Wayal,&nbsp;Jennifer Hollowell","doi":"10.1002/mhs2.70035","DOIUrl":"https://doi.org/10.1002/mhs2.70035","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Digital self-help interventions for mental health can improve symptoms of common mental disorders such as depression and anxiety. However, such online interventions remain inaccessible to the majority of people in LMICs due to a lack of smartphone access, internet signal and/or affordability of data. However, radio persists as a key form of information and entertainment, and remains the most popular form of mass media in Africa. This study aimed to improve the accessibility of a well-evidenced online self-help intervention (WHO's Step-by-Step) by adapting it for delivery over radio. The objectives were to a) explore the feasibility of adapting the intervention to radio and b) evaluate impacts on mental health symptoms in adults with mild-moderate depression and/or anxiety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The Lumuno radio campaign was adapted from WHO's Step-by-Step intervention using formative research with mental health researchers, clinical professionals, community groups and people with lived experience of mental illness. The resulting radio campaign was broadcast daily, at high intensity, for 26 weeks. A mixed-methods pilot study, including a pre-post panel of 440 individuals recruited from Mazabuka town, Zambia, was used to evaluate the campaign's impact on depression and anxiety levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mean depression score (PHQ-9) decreased by 19.7% (effect size −0.65, <i>p</i> &lt; 0.001) and mean anxiety score (GAD-7) dropped by 10.7% (effect size −0.22, <i>p</i> &lt; 0.05). At endline, 41% and 54% respectively of those who had moderate to moderately severe depression, or moderate anxiety at baseline achieved a clinically significant reduction in symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This is the first study to indicate that a radio campaign promoting self-help for depression and anxiety is feasible and may significantly improve mental health outcomes, however, a more rigorous trial is needed to confirm these promising pilot results. Radio may provide an accessible and cost-effective platform for delivering mental health support in Zambia and, potentially, other LMIC contexts where radio listenership is high.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145750901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adapting WHO's Step-By-Step Digital Intervention for Anxiety and Depression for Delivery Via Radio: Development, Piloting and Mixed-Methods Evaluation of the Lumuno Radio Campaign In Zambia","authors":"Abbie Clare,&nbsp;Rina Mukumba,&nbsp;Megan Mclaren,&nbsp;Naeem Dalal,&nbsp;Joanna Murray,&nbsp;Sonali Wayal,&nbsp;Jennifer Hollowell","doi":"10.1002/mhs2.70035","DOIUrl":"https://doi.org/10.1002/mhs2.70035","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Digital self-help interventions for mental health can improve symptoms of common mental disorders such as depression and anxiety. However, such online interventions remain inaccessible to the majority of people in LMICs due to a lack of smartphone access, internet signal and/or affordability of data. However, radio persists as a key form of information and entertainment, and remains the most popular form of mass media in Africa. This study aimed to improve the accessibility of a well-evidenced online self-help intervention (WHO's Step-by-Step) by adapting it for delivery over radio. The objectives were to a) explore the feasibility of adapting the intervention to radio and b) evaluate impacts on mental health symptoms in adults with mild-moderate depression and/or anxiety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The Lumuno radio campaign was adapted from WHO's Step-by-Step intervention using formative research with mental health researchers, clinical professionals, community groups and people with lived experience of mental illness. The resulting radio campaign was broadcast daily, at high intensity, for 26 weeks. A mixed-methods pilot study, including a pre-post panel of 440 individuals recruited from Mazabuka town, Zambia, was used to evaluate the campaign's impact on depression and anxiety levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mean depression score (PHQ-9) decreased by 19.7% (effect size −0.65, <i>p</i> &lt; 0.001) and mean anxiety score (GAD-7) dropped by 10.7% (effect size −0.22, <i>p</i> &lt; 0.05). At endline, 41% and 54% respectively of those who had moderate to moderately severe depression, or moderate anxiety at baseline achieved a clinically significant reduction in symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This is the first study to indicate that a radio campaign promoting self-help for depression and anxiety is feasible and may significantly improve mental health outcomes, however, a more rigorous trial is needed to confirm these promising pilot results. Radio may provide an accessible and cost-effective platform for delivering mental health support in Zambia and, potentially, other LMIC contexts where radio listenership is high.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145750902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Behavioral Threat Avoidance in Pediatric Anxiety With Naturalistic Games","authors":"Purnima Qamar,&nbsp;Eli R. Lebowitz,&nbsp;Rany Abend,&nbsp;Daniel S. Pine,&nbsp;Peter A. Kirk","doi":"10.1002/mhs2.70036","DOIUrl":"10.1002/mhs2.70036","url":null,"abstract":"<p>Behavioral avoidance exacerbates anxiety symptoms. Capturing and identifying maladaptive avoidance patterns holds clinical utility. However, effective assessment tools which provide unique information on behavior beyond self-report are needed. Here, we assess the replicability of an interactive game to distinguish between clinically anxious and healthy youth's behavioral avoidance. One hundred and fifteen youth (8–17 years old) completed the Yale Interactive Kinect Environment Software (YIKES) paradigm, whereby behavioral avoidance of aversive and non-aversive faces is captured. Our primary, preregistered analyses used mixed ANOVA models to test differences in behavioral avoidance by diagnostic status, clinician-reported avoidance, and self-reported social anxiety symptoms. Secondary, non-preregistered analyses pooled data across two published studies (<i>n</i> = 189 youth). Primary analyses found no association between clinician-rated anxiety symptoms and avoidance (<i>ps</i> &gt; 0.296). A secondary, pooled analysis with additional data indicated a positive association between self-reported social anxiety symptom severity and avoidance of aversive faces (<i>r</i> = 0.25, <i>p</i> &lt; 0.001). A positive association also emerged between overall self-reported anxiety symptoms and avoidance of aversive faces (<i>r</i> = 0.18, <i>p</i> = 0.014). Here, we provide evidence that a naturalistic interactive game is effective for capturing avoidance patterns. While no associations with clinician-rated measures emerged, behavioral avoidance was correlated with self-reported anxiety. This appeared stronger for social anxiety compared to overall anxiety symptom severity. Our results suggest that self-report may be more sensitive to capturing behavioral patterns of avoidance than clinician-report, although replication and further work building on this paradigm is warranted.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145619339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Narrative Synthesis of Mental Health Clinicians' Attitudes Toward Online Therapy","authors":"Tamara M. Whitehead,&nbsp;Duaa H. Alrashdi,&nbsp;Shiyi Bin,&nbsp;Eugenia Drini","doi":"10.1002/mhs2.70039","DOIUrl":"https://doi.org/10.1002/mhs2.70039","url":null,"abstract":"<p>Online psychological therapy practices have increased in frequency in recent years, especially since the onset of the COVID-19 pandemic. Recent research has proven their effectiveness; however, mental health clinicians' attitudes toward their use have been less explored. This is important as these attitudes can influence patient outcomes and the implementation of evidence-based interventions. As such, we aimed to explore mental health clinicians' attitudes toward online therapy through a systematic review. Four electronic databases (MEDLINE, PsycINFO, Web of Science, and Scopus) were searched, as well as gray literature (PsycEXTRA and ProQuest) and manual searches of Overton, charity websites, Google Scholar, and reference lists. Themes were identified from the resulting qualitative studies, and quantitative and mixed methods studies were mapped onto these themes using a matrix. The synthesis followed a narrative approach. Thirteen themes were discovered from the 28 included studies, which highlight a range of clinicians' attitudes toward online therapy, both positive and negative. Themes consist of the therapeutic relationship, communication and relational aspects, time and space, technical aspects, professional self-doubt, individual differences, practical aspects, patient privacy, risk, perception of patient experience, transition to online therapy, change in attitude with the pandemic, and general attitudes/future intentions. Clinicians generally had somewhat positive attitudes toward online therapy, especially since the COVID-19 pandemic; however, they also identified key limitations. Training clinicians to use technology and online modalities might be a key direction for future clinical practice and research to improve clinicians' confidence and attitudes toward online therapy.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145626038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Narrative Synthesis of Mental Health Clinicians' Attitudes Toward Online Therapy","authors":"Tamara M. Whitehead,&nbsp;Duaa H. Alrashdi,&nbsp;Shiyi Bin,&nbsp;Eugenia Drini","doi":"10.1002/mhs2.70039","DOIUrl":"https://doi.org/10.1002/mhs2.70039","url":null,"abstract":"<p>Online psychological therapy practices have increased in frequency in recent years, especially since the onset of the COVID-19 pandemic. Recent research has proven their effectiveness; however, mental health clinicians' attitudes toward their use have been less explored. This is important as these attitudes can influence patient outcomes and the implementation of evidence-based interventions. As such, we aimed to explore mental health clinicians' attitudes toward online therapy through a systematic review. Four electronic databases (MEDLINE, PsycINFO, Web of Science, and Scopus) were searched, as well as gray literature (PsycEXTRA and ProQuest) and manual searches of Overton, charity websites, Google Scholar, and reference lists. Themes were identified from the resulting qualitative studies, and quantitative and mixed methods studies were mapped onto these themes using a matrix. The synthesis followed a narrative approach. Thirteen themes were discovered from the 28 included studies, which highlight a range of clinicians' attitudes toward online therapy, both positive and negative. Themes consist of the therapeutic relationship, communication and relational aspects, time and space, technical aspects, professional self-doubt, individual differences, practical aspects, patient privacy, risk, perception of patient experience, transition to online therapy, change in attitude with the pandemic, and general attitudes/future intentions. Clinicians generally had somewhat positive attitudes toward online therapy, especially since the COVID-19 pandemic; however, they also identified key limitations. Training clinicians to use technology and online modalities might be a key direction for future clinical practice and research to improve clinicians' confidence and attitudes toward online therapy.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145626039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediators in the Relationship Between Attention-Deficit/Hyperactivity Disorder Symptoms and Disordered Eating Symptoms: A Scoping Review","authors":"Lauris Annatha Mariam Auch,&nbsp;Andreas Riedel,&nbsp;Kerstin Gabriel Felleiter,&nbsp;Salvatore Corbisiero","doi":"10.1002/mhs2.70038","DOIUrl":"10.1002/mhs2.70038","url":null,"abstract":"<p>Attention-deficit/hyperactivity disorder (ADHD) is associated with disordered eating habits, and individuals with eating disorders show more ADHD symptoms. Little is known about the underlying mechanism of this association. In this scoping review, we aim to provide an overview of researched mediators in adults and discuss implications for future research. We followed the <i>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</i> extension for Scoping Reviews Checklist. A literature search was conducted on PubMed, Ovid, and PubPsych. We included studies written in English or German and conducted on adults (18+ years). Of the 884 search results, 22 studies were included. <i>N</i> = 11 studies examined hyperactivity/impulsivity as a mediator, <i>n</i> = 8 inattention, <i>n</i> = 5 emotion dysregulation/emotional eating, <i>n</i> = 7 depression, negative mood, and/or anxiety, <i>n</i> = 6 general genetics and genetics in dopamine signaling pathways, <i>n</i> = 3 attractiveness of food, <i>n</i> = 4 interoceptive awareness/sensitivity, <i>n</i> = 2 general psychopathological symptoms and personality factors, and <i>n</i> = 1 circadian rhythm disruption. Inattention, hyperactivity, and impulsivity are cross-sectionally well-researched mediators but do not seem to mediate either a total or a causal relationship. Emotion dysregulation as well as the role of the dopaminergic reward system, including addictive-like behavior, seem to be involved as mediators and should receive more attention. Future research should not only focus on investigating one mediator while controlling for comorbidities and confounding factors but should also include prospective longitudinal study designs.</p>","PeriodicalId":94140,"journal":{"name":"Mental health science","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mhs2.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}