Medicina intensiva最新文献_第2页

The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study 败血症患者体温与 28 天死亡率之间的关系：回顾性观察研究

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.08.004

Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen

引用次数: 0

Impact of patient safety on outcomes. From prevention to the treatment of post-intensive care syndrome 患者安全对疗效的影响。从预防到治疗重症监护后综合征。

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.04.008

Carola Giménez-Esparza , María Ángeles Relucio , Kapil Laxman Nanwani-Nanwani , José Manuel Añón

{"title":"Impact of patient safety on outcomes. From prevention to the treatment of post-intensive care syndrome","authors":"Carola Giménez-Esparza , María Ángeles Relucio , Kapil Laxman Nanwani-Nanwani , José Manuel Añón","doi":"10.1016/j.medine.2024.04.008","DOIUrl":"10.1016/j.medine.2024.04.008","url":null,"abstract":"<div><div>Survivors of critical illness may present physical, psychological, or cognitive symptoms after hospital discharge, encompassed within what is known as post-intensive care syndrome. These alterations result from both the critical illness itself and the medical interventions surrounding it. For its prevention, the implementation of the ABCDEF bundle (Assess/treat pain, Breathing/awakening trials, Choice of sedatives, Delirium reduction, Early mobility and exercise, Family) has been proposed, along with additional strategies grouped under the acronym GHIRN (Good communication, Handout materials, Redefined ICU architectural design, Respirator, Nutrition). In addition to these preventive measures during the ICU stay, high-risk patients should be identified for subsequent follow-up through multidisciplinary teams coordinated by Intensive Care Medicine Departments.</div></div>","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":"49 4","pages":"Pages 224-236"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140767854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When fat-free parenteral nutrition is required: The strategy that becomes a double-edge sword 需要无脂肪肠外营养时：成为双刃剑的策略

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.09.003

Marta de Antonio-Cuscó , Agustí Albalat-Torres , Lucía Picazo Moreno , Javier Mateu-de Antonio

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Academic disobey 学术不服从。

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.10.008

Marcos Valiente Fernández, Francisco de Paula Delgado Moya, Amanda Lesmes González de Aledo, Isaías Martín Badía

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Material and human resources invested in a program aimed at potentially critical trauma patients in the emergency department 为一项针对潜在危重创伤患者的计划投入物力和人力。

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.11.001

Alejandro Arturo Caballo Manuel, Carlos García Fuentes, Jesús Barea Mendoza, Susana Bermejo-Aznáres, Mario Chico-Fernández

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Shocked and moved. Early mobilisation in cardiogenic shock 震惊与感动。心源性休克患者的早期动员。

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.11.006

José Luis García-Garmendia

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Comparisons are odious

Medicina intensiva Pub Date : 2025-04-01 DOI: 10.1016/j.medine.2024.10.010

Marcos Valiente Fernández, Alejandro Caballo Manuel, José Ginestal Calvo, Lidia Orejon García

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β-lactam antibiotics to prevent ventilator-associated pneumonia (VAP) in coma patients: A systematic review and meta-analysis of randomized controlled trials.

Medicina intensiva Pub Date : 2025-03-25 DOI: 10.1016/j.medine.2025.502199

Edinson Dante Meregildo-Rodriguez, Mariano Ortiz-Pizarro, Martha Genara Asmat-Rubio, Carlos Geraldo Fernandez-Narváez, Gustavo Adolfo Vásquez-Tirado

{"title":"β-lactam antibiotics to prevent ventilator-associated pneumonia (VAP) in coma patients: A systematic review and meta-analysis of randomized controlled trials.","authors":"Edinson Dante Meregildo-Rodriguez, Mariano Ortiz-Pizarro, Martha Genara Asmat-Rubio, Carlos Geraldo Fernandez-Narváez, Gustavo Adolfo Vásquez-Tirado","doi":"10.1016/j.medine.2025.502199","DOIUrl":"https://doi.org/10.1016/j.medine.2025.502199","url":null,"abstract":"Objective: To evaluate the effect of parenteral β-lactam antibiotics on outcomes related to ventilator-associated pneumonia (VAP) in adult patients in coma due to acute brain injury (ABI).Design: Systematic review and meta-analysis.Setting: Randomized controlled trials (RCTs) published up toSeptember 30, 2024.Patients or participants: Adult patients in coma due to ABI.Interventions: Parenteral β-lactam antibiotics.Main variables of interest: Incidence and outcomes related to VAP.Results: Three RCTs involving 483 patients met inclusion criteria; 231 patients received β-lactam prophylaxis. Among these, there were 115 cases of early-onset VAP (EO-VAP), 49 of late-onset VAP (LO-VAP), and 102 deaths. All studies were conducted in Europe. Causes of coma included trauma, stroke, and CO poisoning. Intravenous β-lactams (ampicillin/sulbactam, cefuroxime, and ceftriaxone) reduced EO-VAP risk by 57% (RR 0.43; 95% CI 0.30-0.61), and all-VAP by 35% (RR 0.65; 95% CI 0.53-0.80). No impact was observed on LO-VAP (RR 0.95; 95% CI 0.54-1.67), 28-day mortality (RR 0.76; 95% CI 0.53-1.09), intubation duration (SMD -0.13; 95% CI -0.46-0.21), or ICU length of stay (SMD -0.22; 95% CI -0.55-0.12). Heterogeneity and the risk of bias were low, with high overall evidence certainty.Conclusions: In adult patients in coma due to ABI, intravenous β-lactam antibiotics reduce EO-VAP and all-VAP risk.","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":" ","pages":"502199"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Penetrating trauma in Spain: analysis of the Spanish trauma registry (RETRAUCI).

Medicina intensiva Pub Date : 2025-03-25 DOI: 10.1016/j.medine.2025.502165

Judit Gutiérrez-Gutiérrez, Jesús Abelardo Barea-Mendoza, Carlos García-Fuentes, Juan Antonio Llompart-Pou, Begoña Guardiola-Grau, Mikel Durán-Suquía, María Ángeles Ballesteros-Sanz, Javier González-Robledo, Lluís Serviá-Goixart, Cristina Méndez-Benegassi Cid, Jose Maria Toboso Casado, Mario Chico-Fernández

{"title":"Penetrating trauma in Spain: analysis of the Spanish trauma registry (RETRAUCI).","authors":"Judit Gutiérrez-Gutiérrez, Jesús Abelardo Barea-Mendoza, Carlos García-Fuentes, Juan Antonio Llompart-Pou, Begoña Guardiola-Grau, Mikel Durán-Suquía, María Ángeles Ballesteros-Sanz, Javier González-Robledo, Lluís Serviá-Goixart, Cristina Méndez-Benegassi Cid, Jose Maria Toboso Casado, Mario Chico-Fernández","doi":"10.1016/j.medine.2025.502165","DOIUrl":"https://doi.org/10.1016/j.medine.2025.502165","url":null,"abstract":"Objective: To describe the epidemiology of penetrating trauma, mortality associated factors and its management in Spanish intensive care units.Design: Multicenter, prospective registry. A comparison is established between two cohorts defined by the type of trauma (blunt and penetrating).Patients: Patients with traumatic injury admitted to the participating ICUs from June 2015 to June 2022.Interventions: None.Main variable of interest: Epidemiology, injury pattern, prehospital and hospital care, resource utilization, and clinical outcomes.Results: 12,806 patients were eligible, of whom 821 (6.4%) suffered penetrating trauma; 418 patients (50.9%) from stab wounds, 93 (11.3%) from gunshot wounds, and 310 (37.8%) from other objects. The most common intent was assault (47.7%). The mean ISS was 15.2 ± 10.6 in penetrating trauma and 19.8 ± 11.9 in blunt trauma (p < 0.001). ICU mortality was 7.8% compared to 11.7% in blunt trauma, with deaths more frequently occurring within the first 24 hours (64% vs. 39%). Factors associated with mortality included female sex, prior use of antithrombotic agents, older age, higher NISS score, and the presence of cranial trauma or shock.Conclusions: Penetrating trauma is an emergent pathology in our context with high complexity, highlighting the need for focused study and documentation, protocol development, and resource optimization to provide quality care.","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":" ","pages":"502165"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-CoV-2 vaccination reduces the risk of thrombotic complications in severe COVID-19.

Medicina intensiva Pub Date : 2025-03-21 DOI: 10.1016/j.medine.2025.502167

M Ángeles Alonso Fernández, Carola Bledig, Madian Manso Álvarez, Raquel Gómez Guardiola, Marina Blancas García, Irene Bartolomé, Manuel Quintana Díaz, Pilar Marcos Neira, Jose Alberto Silva Obregón, Ainhoa Serrano Lázaro, Salvador Campillo Morales, Blanca López Matamala, Carmen Martín Parra, Ángela Algaba Calderón, Rafael Blancas Gómez-Casero, Óscar Martínez González

{"title":"SARS-CoV-2 vaccination reduces the risk of thrombotic complications in severe COVID-19.","authors":"M Ángeles Alonso Fernández, Carola Bledig, Madian Manso Álvarez, Raquel Gómez Guardiola, Marina Blancas García, Irene Bartolomé, Manuel Quintana Díaz, Pilar Marcos Neira, Jose Alberto Silva Obregón, Ainhoa Serrano Lázaro, Salvador Campillo Morales, Blanca López Matamala, Carmen Martín Parra, Ángela Algaba Calderón, Rafael Blancas Gómez-Casero, Óscar Martínez González","doi":"10.1016/j.medine.2025.502167","DOIUrl":"https://doi.org/10.1016/j.medine.2025.502167","url":null,"abstract":"Objectives: The aim of this study was to evaluate the association between SARS-CoV-2 vaccination and the occurrence of thrombotic complications in patients admitted to intensive care for severe COVID-19 pneumonia.Design: Observational, descriptive, prospective, multicentre study.Setting: Intensive care units of five university hospitals.Patients: A total of 255 patients admitted to the intensive care unit (ICU) with SARS-CoV-2 pneumonia, confirmed by RT-PCR in throat swab or tracheal aspirate, starting the date the first vaccinated patient against SARS-CoV-2 was admitted in one of the participating ICUs, were included in the analysis.Main variables of interest: Vaccination status against SARS-CoV-2 and thrombotic events.Results: 18.8% of patients had received some form of vaccination. Thrombotic events occurred in 21.2% of patients. Lack of vaccination was associated with thrombotic events (OR 5.024; 95% CI: 1.104-23.123; p = 0.0037) and death (OR 5.161; 95% CI: 1.075-24.787; p = 0.04). ICU mortality was not associated with the occurrence of thrombotic complications.Conclusions: In this series of patients, vaccination against SARS-CoV-2 reduced the risk of thrombotic events and mortality in patients with severe COVID-19 admitted to the ICU. Thrombotic complications did not alter ICU mortality.","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":" ","pages":"502167"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0