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La Revue du praticien最新文献

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[VEXAS Syndrome]. (VEXAS综合症)。
La Revue du praticien Pub Date : 2025-02-01
Vincent Jachiet, Thibault Comont, Olivier Kosmider, Lin Pierre Zhao, Arsène Mekinian, Olivier Fain, Jérome Hadjadj
{"title":"[VEXAS Syndrome].","authors":"Vincent Jachiet, Thibault Comont, Olivier Kosmider, Lin Pierre Zhao, Arsène Mekinian, Olivier Fain, Jérome Hadjadj","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>VEXAS SYNDROME. VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) syndrome is a recently described autoinflammatory syndrome, mostly affecting men above 50 years, caused by somatic mutation in the X-linked UBA1 gene. Patients present a broad spectrum of inflammatory manifestations (fever, neutrophilic dermatosis, chondritis, pulmonary infiltrates, ocular inflammation, venous thrombosis) with hematological involvement (macrocytic anemia, thrombocytopenia, vacuoles in myeloid and erythroid precursor cells, dysplastic bone marrow) which are responsible for significant morbidity and mortality. The therapeutic management is currently poorly codified, and based on two main approaches: controlling inflammatory symptoms by using corticosteroids, JAK inhibitors or tocilizumab, or targeting the UBA1-mutated hematopoietic population using azacitidine or allogeneic hematopoietic stem cell transplantation.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"196-200"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Impacts of endocrine disruptors on the placenta]. [内分泌干扰物对胎盘的影响]
La Revue du praticien Pub Date : 2025-02-01
Florence Joly
{"title":"[Impacts of endocrine disruptors on the placenta].","authors":"Florence Joly","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>IMPACTS OF ENDOCRINE DISRUPTORS ON THE PLACENTA. The placenta is a transitional organ that plays a major role during pregnancy, providing the vital functions required for the development of the fetus. However, its development and functions are still poorly understood. Exposure of pregnant women to chemical substances such as endocrine disruptors (ED) significantly impacts the placental development and disrupts its functioning. The impact of EDs on the placenta is primarily reflected in the increased occurrence of pregnancy complications, negatively influences the development of the fetus and contributes to the onset of chronic pathologies in childhood (asthma, obesity, IHD, ADHD, etc.) and adulthood (hormone-dependent cancers, diabetes, etc.). Recent data from studies carried out in vitro, in vivo, in experimental models or through epidemiological studies have enabled to better characterize the molecular pathways impacted, the physiological processes altered, and the consequences of exposure to EDs on the placenta.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"187-195"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Advances and integration of nuclear medicine in clinical practice]. [核医学在临床实践中的进展与整合]。
La Revue du praticien Pub Date : 2025-02-01
Laura Rozenblum
{"title":"[Advances and integration of nuclear medicine in clinical practice].","authors":"Laura Rozenblum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>ADVANCES AND INTEGRATION OF NUCLEAR MEDICINE IN CLINICAL PRACTICE. Nuclear medicine, a rapidly expanding field, plays a significant role in current technological and therapeutic advancements, particularly in oncology. Using radioactive substances for imaging and treatment, this specialty focuses on the use of radiopharmaceuticals that precisely target pathophysiological processes at the molecular level. This approach offers a functional rather than anatomical perspective of organs. Recent innovations include the development of new radiotracers, technical improvements in imaging cameras, and the expansion of radiopeptides ligand therapies applications to new diseases. The adoption of artificial intelligence in nuclear medicine is also revolutionizing the practice, making patient care less invasive while significantly increasing the speed and accuracy of diagnostics.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"160-163"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Open Forum Scientific analysis 2017-2024 of the Levothyrox crisis by the Association française des malades de la thyroïde]. [开放论坛科学分析2017-2024年左甲状腺危机由法国健康协会thyroïde]。
La Revue du praticien Pub Date : 2025-02-01
Jacques Guillet
{"title":"[Open Forum Scientific analysis 2017-2024 of the Levothyrox crisis by the Association française des malades de la thyroïde].","authors":"Jacques Guillet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Principle of equal access to healthcare for prisoners]. [囚犯平等获得医疗保健的原则]。
La Revue du praticien Pub Date : 2025-02-01
André Ferragne
{"title":"[Principle of equal access to healthcare for prisoners].","authors":"André Ferragne","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>PRINCIPLE OF EQUAL ACCESS TO HEALTHCARE FOR PRISONERS. The law of 18 January 1994, which vested the responsibility for the healthcare of prisoners in the public hospital service, has enabled the development of a comprehensive range of healthcare services. However, equal access to healthcare for prisoners is not completely ensured, because the conditions under which medical care is provided in prison exacerbate the diff iculties experienced by the hospital system in general, and the healthcare provision, theoretically egalitarian, does not suff iciently consider the significant health vulnerability of the prison population. Health units remain distant from the hospitals to which they are attached, and the security constraints imposed by prison can hinder access to care. While prison may off er an initial opportunity for contact with a doctor, it cannot be a place of care; for serious or chronic illnesses, suspensions of sentence for medical reasons must be developed.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"138-140"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Etiologic diagnosis of febrile exanthema in children]. [儿童热性疹的病因学诊断]。
La Revue du praticien Pub Date : 2025-01-01
Florie Solignac, Laura Poujade, Didier Bessis, Éric Jeziorski
{"title":"[Etiologic diagnosis of febrile exanthema in children].","authors":"Florie Solignac, Laura Poujade, Didier Bessis, Éric Jeziorski","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Inverted P waves]. [倒P波]。
La Revue du praticien Pub Date : 2025-01-01
Charlène Fraysse, Victoria Picquendar, Livia Mannaioni, Malika Roumeliotis, Valentin Gadeyne
{"title":"[Inverted P waves].","authors":"Charlène Fraysse, Victoria Picquendar, Livia Mannaioni, Malika Roumeliotis, Valentin Gadeyne","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[When and how should a stool blood test be prescribed?] 何时及如何进行粪便血液检查？］
La Revue du praticien Pub Date : 2025-01-01
Bernard Denis, Lionel Tabard, Christelle Guillon, Julien L'hirondel, Callum G Fraser
{"title":"[When and how should a stool blood test be prescribed?]","authors":"Bernard Denis, Lionel Tabard, Christelle Guillon, Julien L'hirondel, Callum G Fraser","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"13-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Chemsex: a growing and evolving practice]. [Chemsex：一种不断发展的实践]。
La Revue du praticien Pub Date : 2025-01-01
Jean-Victor Blanc
{"title":"[Chemsex: a growing and evolving practice].","authors":"Jean-Victor Blanc","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Chemsex: </strong>A GROWING AND EVOLVING PRACTICE. Chemsex, the voluntary use of psychoactive substances to facilitate, initiate, increase, intensify or prolong sexual relations and performance, often involves multiple substance use. These include synthetic cathinones, methamphetamine, ketamine and cocaine, all of which can induce psychic disorders. This article presents the current state of this practice, its psychiatric complications and its management. As dual pathologies are frequent, it is essential that people with problematic chemsex use should be able to have dual psychiatric and addictological follow-up when necessary.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"75-79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Algorithm for the management of pulmonary arterial hypertension]. 肺动脉高压的处理算法。
La Revue du praticien Pub Date : 2025-01-01
Marianne Riou, Sabina Salinas, Olivier Sitbon
{"title":"[Algorithm for the management of pulmonary arterial hypertension].","authors":"Marianne Riou, Sabina Salinas, Olivier Sitbon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>ALGORITHM FOR THE MANAGEMENT OF PULMONARY ARTERIAL HYPERTENSION. The management of pulmonary arterial hypertension (PAH) has improved significantly in recent years due to advances in the understanding of the pathophysiological mechanisms of the disease, the development of innovative medications and the use of more aggressive therapeutic strategies. Because PAH is a rare disease, it must be managed in a pulmonary hypertension (PH) expert center. PAH management combines general measures, symptomatic treatments and «specific» therapies targeting the vasoconstriction/vasodilation and pro-proliferation/anti-proliferation balance of the pulmonary arteries. Despite major therapeutic advances in recent years, the prognosis for PAH remains poor and lung transplantation (or cardiopulmonary) transplantation is currently the only curative treatment available for the most severe patients.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"43-49"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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