Emma D'Anglejan, Frédérique Bouchand, Aurélien Dinh
{"title":"[When should shortterm antibiotic therapy be chosen?]","authors":"Emma D'Anglejan, Frédérique Bouchand, Aurélien Dinh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>WHEN SHOULD SHORT-TERM ANTIBIOTIC THERAPY BE CHOSEN? Reducing antibiotic exposure by shortening treatment duration is a public health priority that could mitigate the emergence of bacterial resistance, minimize adverse effects, and lower costs. Additionally, a short yet effective antibiotic regimen is associated with improved patient compliance and satisfaction. Several trials in recent years have confirmed the efficacy of shorter treatment durations. For instance, five days of antibiotics are sufficient for uncomplicated pyelonephritis, while seven days suffice for non-febrile urinary tract infections in males. However, a 14-day regimen appears necessary for febrile urinary tract infections in men. A study examining a five-day treatment period found no difference compared to a 10-day regimen for skin and soft tissue infections. In acute community-acquired pneumonia, two randomized trials found three days of beta-lactam therapy to be effective. In intra-abdominal infections, durations ranging from four to eight days were found to be non-inferior to 15-day courses in two trials. Regarding osteoarticular infections, six weeks are adequate for spondylodiscitis, whereas 12 weeks are required for prosthetic joint infections. These findings validate shorter treatment durations across many clinical scenarios. However, in rare conditions such as febrile male urinary tract infections and prosthetic joint infections, shortening the duration may not be feasible. It is imperative to prescribe the shortest effective antibiotic duration possible in routine medical practice to combat antibiotic resistance.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"74 7","pages":"703-709"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[What role does the precautionary principle play in medicine?]","authors":"Alain C Masquelet, Jacques De Saint-Julien","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"74 7","pages":"710-713"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Management of varicose disease].","authors":"Laurent Baudino, Luc Bressollette","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>MANAGEMENT OF VARICOSE DISEASE. Chronic venous disease (CVD) is a chronic condition for which there is no cure. The therapeutic approach to CVD varies depending on the severity of the disease and must be individually adapted. There are two main treatment options: conservative treatment and interventional treatment. Conservative treatment consists in applying the classic venous hygiene guidelines to prevent the progression of the disease by encouraging the patient to modify his lifestyle. It includes general measures such as recommending exercise, weight management and the use of compression products. Pharmacological treatment, although controversial, may be prescribed to relieve symptoms associated with CVD. However, its effectiveness may vary from one individual to another. Interventional treatment has changed a lot. During the 20th century, open surgery was the dominant method for treating varicose disease. Nevertheless, the indications for this intervention have recently evolved thanks to the development of endovenous intervention techniques, whether they are thermal or not. These advances now make it possible to treat varicose veins on an outpatient basis. The management of CVD is not based on a single treatment, but rather on a combination aiming at relieving symptoms, preventing complications and slowing its progression.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"74 7","pages":"751-757"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}