Vincent Jachiet, Thibault Comont, Olivier Kosmider, Lin Pierre Zhao, Arsène Mekinian, Olivier Fain, Jérome Hadjadj
{"title":"[VEXAS Syndrome].","authors":"Vincent Jachiet, Thibault Comont, Olivier Kosmider, Lin Pierre Zhao, Arsène Mekinian, Olivier Fain, Jérome Hadjadj","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>VEXAS SYNDROME. VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) syndrome is a recently described autoinflammatory syndrome, mostly affecting men above 50 years, caused by somatic mutation in the X-linked UBA1 gene. Patients present a broad spectrum of inflammatory manifestations (fever, neutrophilic dermatosis, chondritis, pulmonary infiltrates, ocular inflammation, venous thrombosis) with hematological involvement (macrocytic anemia, thrombocytopenia, vacuoles in myeloid and erythroid precursor cells, dysplastic bone marrow) which are responsible for significant morbidity and mortality. The therapeutic management is currently poorly codified, and based on two main approaches: controlling inflammatory symptoms by using corticosteroids, JAK inhibitors or tocilizumab, or targeting the UBA1-mutated hematopoietic population using azacitidine or allogeneic hematopoietic stem cell transplantation.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"196-200"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Advances and integration of nuclear medicine in clinical practice].","authors":"Laura Rozenblum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>ADVANCES AND INTEGRATION OF NUCLEAR MEDICINE IN CLINICAL PRACTICE. Nuclear medicine, a rapidly expanding field, plays a significant role in current technological and therapeutic advancements, particularly in oncology. Using radioactive substances for imaging and treatment, this specialty focuses on the use of radiopharmaceuticals that precisely target pathophysiological processes at the molecular level. This approach offers a functional rather than anatomical perspective of organs. Recent innovations include the development of new radiotracers, technical improvements in imaging cameras, and the expansion of radiopeptides ligand therapies applications to new diseases. The adoption of artificial intelligence in nuclear medicine is also revolutionizing the practice, making patient care less invasive while significantly increasing the speed and accuracy of diagnostics.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"160-163"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Open Forum Scientific analysis 2017-2024 of the Levothyrox crisis by the Association française des malades de la thyroïde].","authors":"Jacques Guillet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Principle of equal access to healthcare for prisoners].","authors":"André Ferragne","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>PRINCIPLE OF EQUAL ACCESS TO HEALTHCARE FOR PRISONERS. The law of 18 January 1994, which vested the responsibility for the healthcare of prisoners in the public hospital service, has enabled the development of a comprehensive range of healthcare services. However, equal access to healthcare for prisoners is not completely ensured, because the conditions under which medical care is provided in prison exacerbate the diff iculties experienced by the hospital system in general, and the healthcare provision, theoretically egalitarian, does not suff iciently consider the significant health vulnerability of the prison population. Health units remain distant from the hospitals to which they are attached, and the security constraints imposed by prison can hinder access to care. While prison may off er an initial opportunity for contact with a doctor, it cannot be a place of care; for serious or chronic illnesses, suspensions of sentence for medical reasons must be developed.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 2","pages":"138-140"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Florie Solignac, Laura Poujade, Didier Bessis, Éric Jeziorski
{"title":"[Etiologic diagnosis of febrile exanthema in children].","authors":"Florie Solignac, Laura Poujade, Didier Bessis, Éric Jeziorski","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bernard Denis, Lionel Tabard, Christelle Guillon, Julien L'hirondel, Callum G Fraser
{"title":"[When and how should a stool blood test be prescribed?]","authors":"Bernard Denis, Lionel Tabard, Christelle Guillon, Julien L'hirondel, Callum G Fraser","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"13-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Chemsex: a growing and evolving practice].","authors":"Jean-Victor Blanc","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Chemsex: </strong>A GROWING AND EVOLVING PRACTICE. Chemsex, the voluntary use of psychoactive substances to facilitate, initiate, increase, intensify or prolong sexual relations and performance, often involves multiple substance use. These include synthetic cathinones, methamphetamine, ketamine and cocaine, all of which can induce psychic disorders. This article presents the current state of this practice, its psychiatric complications and its management. As dual pathologies are frequent, it is essential that people with problematic chemsex use should be able to have dual psychiatric and addictological follow-up when necessary.</p>","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"75-79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Multiple myeloma of the bones].","authors":"Margaret Macro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94123,"journal":{"name":"La Revue du praticien","volume":"75 1","pages":"101-109"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}