Journal of postgraduate medicine最新文献

Report of two cases of lipedema: An under-recognized, misdiagnosed, and under-reported disorder in India. 报告两例脂肪水肿：印度一种未被认识、误诊和未被报告的疾病。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2025-12-10 DOI: 10.4103/jpgm.jpgm_273_25

V S Kuttiatt, M Anandan, N Elangovan, A Sadhasivam

{"title":"Report of two cases of lipedema: An under-recognized, misdiagnosed, and under-reported disorder in India.","authors":"V S Kuttiatt, M Anandan, N Elangovan, A Sadhasivam","doi":"10.4103/jpgm.jpgm_273_25","DOIUrl":"10.4103/jpgm.jpgm_273_25","url":null,"abstract":"Abstract: Lipedema is a chronic adipose tissue disorder primarily affecting women, marked by abnormal, symmetrical, and disproportionate accumulation of subcutaneous fat in the lower limbs and sometimes in the arms, with hands and feet typically spared. Frequently misdiagnosed as lymphedema or obesity, lipedema presents with pain, easy bruising, bilateral nonpitting edema, and swelling that worsens throughout the day. We present two cases: Two middle-aged women reported longstanding bilateral lower limb swelling, pain, and varicose veins, without significant comorbidities. Clinical examination revealed characteristic disproportionate fat distribution and negative Stemmer's sign. Laboratory investigations and lymphoscintigraphy excluded other causes of edema. Imaging confirmed subcutaneous thickening, fat stranding, and varicosities. Both patients were advised to have conservative management including compression therapy, limb elevation, physiotherapy and dietary counseling; one patient had significant limb volume reduction. Our report underscores the importance of recognizing lipedema for early diagnosis and effective management to prevent progression and complications.","PeriodicalId":94105,"journal":{"name":"Journal of postgraduate medicine","volume":" ","pages":"32-36"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13105436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145727096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sinonasal IgG4-related disease: A rare masquerader of sinonasal pathologies. 鼻窦igg4相关疾病：一种罕见的鼻窦病变伪装者。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-01 DOI: 10.4103/jpgm.jpgm_581_25

S Mitra, P Choulera

引用次数: 0

An update on Burkholderia cepacia complex infections in a tertiary care hospital. 一家三级保健医院关于洋葱伯克霍尔德菌复合感染的最新情况。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-16 DOI: 10.4103/jpgm.jpgm_790_25

E Rajni, S Kataria, H Galav

{"title":"An update on Burkholderia cepacia complex infections in a tertiary care hospital.","authors":"E Rajni, S Kataria, H Galav","doi":"10.4103/jpgm.jpgm_790_25","DOIUrl":"10.4103/jpgm.jpgm_790_25","url":null,"abstract":"Abstract: Despite the growing clinical significance of Burkholderia cepacia complex (Bcc), there are lacunae regarding indepth understanding of its epidemiology and management. The present study was conducted to evaluate the clinico-epidemiological profile of patients presenting with Bcc infections and antibiotic susceptibility profile of these clinical isolates.This retrospective observational study was conducted in a tertiary care teaching university hospital, from January' 2018 to December' 2024 and included all Bcc isolates recovered during the study period. Identification and antimicrobial susceptibility testing were done using VITEK 2 compact automated system. A total of 224 Bcc isolates were included in the study. The most predominant age group was >60 years, accounting for 29.5%, and male preponderance was observed. A total of 90% isolates were from inpatients, with 56.7% being admitted to ICUs. Maximum isolates were recovered from blood (61.2%), and diabetes was the most common comorbidity observed (44.6%). Respiratory samples amounted to only 9.8% of isolates. The susceptibility rates observed for ceftazidime, meropenem, trimethoprim-sulfamethoxazole, minocycline, and levofloxacin were 93%, 85.7%, 78.1%, 70%, and 60%, respectively. To the best of our knowledge, this is the first record of clinico-epidemiological and microbiological characteristics of Bcc isolates from Rajasthan. This research could significantly inform clinical practice, optimizing treatment strategies for infections caused by this opportunistic pathogen. Since it is a difficult-to-treat emerging pathogen, regular and systematic surveillance is crucial.","PeriodicalId":94105,"journal":{"name":"Journal of postgraduate medicine","volume":" ","pages":"19-22"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13105433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From bedside to journal: Writing high-quality case reports. 从病床到日志：撰写高质量的病例报告。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-02-20 DOI: 10.4103/jpgm.jpgm_1036_25

C A Divecha, M S Tullu

引用次数: 0

A rare case of duodenal tuberculosis complicated with gastric outlet obstruction in a young female: A case report. 年轻女性罕见的十二指肠结核合并胃出口梗阻1例。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-01 DOI: 10.4103/jpgm.jpgm_805_25

A Shastri, S Rose, S Mitra, A De

引用次数: 0

Algorithmic sycophancy: A new source of systematic distortion in AI-driven biomedical research. 算法谄媚：人工智能驱动的生物医学研究中系统性扭曲的新来源。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-02 DOI: 10.4103/jpgm.jpgm_919_25

H Sharma, M Ruikar

{"title":"Algorithmic sycophancy: A new source of systematic distortion in AI-driven biomedical research.","authors":"H Sharma, M Ruikar","doi":"10.4103/jpgm.jpgm_919_25","DOIUrl":"10.4103/jpgm.jpgm_919_25","url":null,"abstract":"Abstract: Artificial intelligence (AI) systems based on Large Language Model (LLM) are becoming an increasingly important aspect of biomedical research, assisting with the tasks ranging from research design to data analysis and publication. Although AI systems increase productivity by cutting the time taken for individual tasks, they also expose their users to severe risk due to systematic distortion of outputs due to algorithmic sycophancy. The honesty of these AI systems is questionable, and can effortlessly crumble when user prompts are incorrect or when the system is under pressure. This viewpoint emphasizes the fundamental understanding of algorithmic sycophancy and the potential mechanism underlying it, which leads to systematic distortion of biological research. There is an important need to bring this issue to light in order to prevent systematic distortion of biomedical research through the cautious utilization of these LLM-based AI systems. Understanding this threat can also help to minimize the propagation of unreliable findings and literature, which pose a significant safety risk to biomedical research as a whole.","PeriodicalId":94105,"journal":{"name":"Journal of postgraduate medicine","volume":" ","pages":"23-27"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13105447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Injection-site calcified granuloma: A silent complication of repeated intramuscular injections. 注射部位钙化肉芽肿：反复肌内注射的无症状并发症。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-16 DOI: 10.4103/jpgm.jpgm_888_25

R G Sawant, A S Lodha

引用次数: 0

Chyle leak following left axillary lymph node excision in an unusual case of isolated left axillary tuberculous lymphadenitis. 孤立性左腋窝结核性淋巴结炎罕见病例左腋窝淋巴结切除后乳糜漏。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-13 DOI: 10.4103/jpgm.jpgm_784_25

A S Girme, S B Chelani

引用次数: 0

Economic burden of Duchenne muscular dystrophy from a societal perspective in Mumbai, India. 从印度孟买的社会视角看杜氏肌萎缩症的经济负担。

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-16 DOI: 10.4103/jpgm.jpgm_716_25

S Antony, M Muranjan, N J Gogtay

{"title":"Economic burden of Duchenne muscular dystrophy from a societal perspective in Mumbai, India.","authors":"S Antony, M Muranjan, N J Gogtay","doi":"10.4103/jpgm.jpgm_716_25","DOIUrl":"10.4103/jpgm.jpgm_716_25","url":null,"abstract":"Introduction: Healthcare demands of Duchenne muscular dystrophy (DMD) impose a significant burden with the possibility of country-specific differences.Material and methods: Analysis to determine cost-of-illness from a societal perspective was performed by prevalence-based, bottom-up microcosting in 60 boys with DMD between July 2022 and January 2024. Direct (medical and nonmedical), indirect (productivity losses of caregivers) and intangible (cost of suffering monetized by willingness to pay method) costs were estimated. National burden was calculated using India-specific prevalence.Results: The cumulative annual cost for 60 patients was ₹ 23,987,323 (USD 290,157). The total median annual cost per patient was ₹ 268,325 (USD 3245). The national economic burden of DMD was ₹ 20,549,902,776 (248,577,510 USD). The highest cost driver of direct costs was expenditure on complementary and alternative medicines and unapproved therapies (₹ 8,549,790 or USD 103,420). Nature of therapy was a significant predictor of total, direct, and intangible costs ( P < 0.001, 0.003, and < 0.001, respectively). Residence in tier X city was a predictor for direct ( P = 0.042) and intangible costs ( P = 0.032). Residence in urban areas ( P = 0.022) and Mumbai ( P = 0.002) were significant predictors of intangible costs.Conclusions: Despite some limitations, the study provides directions for planning healthcare services for DMD in India by developing standard treatment guidelines, allocation of resources through national health schemes for carrier screening and prenatal diagnosis, promoting evidence-based therapeutic practices, and regulation to curb unscientific therapies. Baseline data are available to decide cost-effectiveness of public expenditure for disease-modifying drugs for DMD.","PeriodicalId":94105,"journal":{"name":"Journal of postgraduate medicine","volume":" ","pages":"6-14"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13105440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synchronous arch arterial occlusion - A clinical impasse? 同步弓动脉闭塞-临床僵局？

IF 1.2

Journal of postgraduate medicine Pub Date : 2026-01-01 Epub Date: 2026-03-11 DOI: 10.4103/jpgm.jpgm_895_25

P Bhatia, P Vaideeswar, R D Patil, P B Iyer

引用次数: 0