Udit Thakur, Jason Nogic, Andrea Comella, Nitesh Nerlekar, Jasmine Chan, Timothy Abrahams, Michael Michail, Adam Nelson, Damini Dey, Brian Ko, Sujith Seneviratne, Adam J Brown
{"title":"Computed tomography coronary angiography assessment of left main coronary artery stenosis severity.","authors":"Udit Thakur, Jason Nogic, Andrea Comella, Nitesh Nerlekar, Jasmine Chan, Timothy Abrahams, Michael Michail, Adam Nelson, Damini Dey, Brian Ko, Sujith Seneviratne, Adam J Brown","doi":"10.1016/j.jcct.2024.07.005","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.07.005","url":null,"abstract":"<p><strong>Background: </strong>Angiographic assessment of left main coronary artery (LMCA) stenosis severity can be unreliable. In cases of ambiguity, intravascular ultrasound (IVUS) can be utilised with a minimal lumen area (MLA) of ≥6 mm<sup>2</sup> an accepted threshold for safe deferral of revascularization. We sought to assess whether quantitative computer tomography coronary angiography (CTCA) measures could assist clinicians making LMCA revascularization decisions when compared with IVUS as gold standard.</p><p><strong>Methods: </strong>Consecutive patients undergoing IVUS assessment of angiographically intermediate LMCA stenosis were included. All patients had undergone 320-slice CTCA <90 days prior to IVUS imaging. Offline quantitative assessment of IVUS- and CT-derived measures were undertaken with the cohort divided into those with significant (s-LMCA) versus non-significant (ns-LMCA) disease using the accepted IVUS threshold.</p><p><strong>Results: </strong>Fifty-eight patients were included, with no difference in mean age (61.5 ± 12.2 vs. 59.7 ± 11.9 years, p = 0.57), diabetic status (24.2% vs 16.0%, p = 0.44) or other baseline demographics between groups. Patients with ns-LMCA had larger CT luminal area (8.64 ± 3.91 vs. 5.41 ± 1.54 mm<sup>2</sup>, p < 0.001), larger minimal lumen diameter (MLD) (3.25 ± 0.74 vs. 2.56 ± 0.38 mm, p < 0.001) and lower area stenosis (45.74 ± 18.10 vs. 60.93 ± 14.68%, p = 0.001). There was a significant positive correlation between CTCA and IVUS MLA (r = 0.68, p < 0.001) and MLD (r = 0.67, p < 0.001). ROC analysis demonstrated CTCA MLA cut-off <8.29 mm<sup>2</sup> provides the greatest negative predictive value and sensitivity in predicting the presence of significant LMCA disease.</p><p><strong>Conclusion: </strong>CTCA derived MLA and MLD have a strong correlation with IVUS. A CTCA derived MLA cut-off <8.29 mm<sup>2</sup> showed greatest clinical utility for predicting the need for further assessment, based on IVUS gold standard.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John P Salvas, Juhi Ramchandani, Purva Patel, Tarek Aridi, Keyur Vora, Olexandr Smolensky, Kristen Olsen, Rohan Dharmakumar, Subha V Raman
{"title":"Lipoprotein(a) and coronary artery disease burden in patients with diabetes.","authors":"John P Salvas, Juhi Ramchandani, Purva Patel, Tarek Aridi, Keyur Vora, Olexandr Smolensky, Kristen Olsen, Rohan Dharmakumar, Subha V Raman","doi":"10.1016/j.jcct.2024.07.001","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.07.001","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Erbay, S. Susarla, D. Lee, V. Manubolu, A. Kinninger, H. Sandhu, D. Behjatnia, O. Bikhazi, K. Ngo, A. Jung, I. Yusufu, T. Ahmad, Budoff M
{"title":"Distribution Of Coronary Plaque Subtypes Among Races Quantified By Automated Coronary Plaque Analysis","authors":"M. Erbay, S. Susarla, D. Lee, V. Manubolu, A. Kinninger, H. Sandhu, D. Behjatnia, O. Bikhazi, K. Ngo, A. Jung, I. Yusufu, T. Ahmad, Budoff M","doi":"10.1016/j.jcct.2024.05.169","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.169","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Krishnan, D. Li, S. Mao, F. Flores, Y. Gao, S. Luo, M. Budoff
{"title":"Comprehensive Assessment Of CT Hounsfield Unit Variation Within Patients, Scanners, And Integrated Measures","authors":"S. Krishnan, D. Li, S. Mao, F. Flores, Y. Gao, S. Luo, M. Budoff","doi":"10.1016/j.jcct.2024.05.150","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.150","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Chamie, R. Okubo, Y. Sobue, U. Kaneko, H. Sato, S. Fujimoto, Y. Nozaki, T. Kajiya, T. Miyoshi, K. Ichikawa, M. Abe, T. Kitagawa, H. Ikenaga, K. Osawa, M. Saji, N. Iguchi, G. Nakazawa, K. Takahashi, T. Ijich, H. Mikamo, A. Kurata, M. Moroi, R. Iijima, A. Lansky, A. Demuyakor, H. Matsuo, U. Hoffmann, J. Min, J. Earls, R. Nakanishi
{"title":"Optimal Threshold For Characterizing Calcified Plaque On Ccta As Determined By Correlation With Oct","authors":"D. Chamie, R. Okubo, Y. Sobue, U. Kaneko, H. Sato, S. Fujimoto, Y. Nozaki, T. Kajiya, T. Miyoshi, K. Ichikawa, M. Abe, T. Kitagawa, H. Ikenaga, K. Osawa, M. Saji, N. Iguchi, G. Nakazawa, K. Takahashi, T. Ijich, H. Mikamo, A. Kurata, M. Moroi, R. Iijima, A. Lansky, A. Demuyakor, H. Matsuo, U. Hoffmann, J. Min, J. Earls, R. Nakanishi","doi":"10.1016/j.jcct.2024.05.189","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.189","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Tremamunno, A. Varga-Szemes, U. Schoepf, E. Zsarnóczay, G. Aquino, J. O'Doherty, M. Vecsey-Nagy, T. Emrich
{"title":"Fully Automated Functional Assessment Of Pre-procedural Cardiac Ct Predicts Outcome In Transcatheter Aortic Valve Replacement Candidates","authors":"G. Tremamunno, A. Varga-Szemes, U. Schoepf, E. Zsarnóczay, G. Aquino, J. O'Doherty, M. Vecsey-Nagy, T. Emrich","doi":"10.1016/j.jcct.2024.05.202","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.202","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Atlas, C. Zhang, A. Reeves, D. Li, T. Atlas, M. Budoff, M. Naghavi
{"title":"AI-enabled Bone Mineral Density Measurement In Coronary Artery Calcium Scans Associated With High Coronary Artery Calcium Independently Of Conventional Risk Factors: Multi-ethnic Study Of Atherosclerosis (mesa)","authors":"K. Atlas, C. Zhang, A. Reeves, D. Li, T. Atlas, M. Budoff, M. Naghavi","doi":"10.1016/j.jcct.2024.05.139","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.139","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Analysis Of Coronary Calcium Scoring Using True Non-contrast And Photon-counting Detector Ct Virtual Non-contrast Reconstructions","authors":"A. Alatoum, S. Pryia","doi":"10.1016/j.jcct.2024.05.137","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.137","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Onuegbu, J. Weber, C. Sarpong, J. Orozco Diaz, E. Wolff, Z. Ali, O. Khalique
{"title":"The Diagnostic Accuracy Of Photon Counting Detector CT Scan In The Detection Of Obstructive Coronary Artery Disease In Comparison To Invasive Coronary Angioraphy In Patients With Agatston Coronary Artery Calcium Score Of Greater Than 1000.","authors":"A. Onuegbu, J. Weber, C. Sarpong, J. Orozco Diaz, E. Wolff, Z. Ali, O. Khalique","doi":"10.1016/j.jcct.2024.05.164","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.164","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sultana, D. Paneitz, B. Badreldin, M. Randhawa, J. Arminder, S. Hedgire
{"title":"Measuring Aortic Root On CTA: A Comparative Study On Different Measurement Techniques","authors":"S. Sultana, D. Paneitz, B. Badreldin, M. Randhawa, J. Arminder, S. Hedgire","doi":"10.1016/j.jcct.2024.05.123","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.123","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}