Ibrain最新文献 - Book学术

Emotional recognition while watching emotional videos: Based on electroencephalography signal analysis and machine learning models 观看情绪视频时的情绪识别：基于脑电图信号分析和机器学习模型

Ibrain Pub Date : 2025-09-19 DOI: 10.1002/ibra.70002

Afshin S. Asl, Sahar Karimpour

{"title":"Emotional recognition while watching emotional videos: Based on electroencephalography signal analysis and machine learning models","authors":"Afshin S. Asl, Sahar Karimpour","doi":"10.1002/ibra.70002","DOIUrl":"https://doi.org/10.1002/ibra.70002","url":null,"abstract":"Depending on the impact of emotions on a person's performance and emotional disorders that can be the main cause of many mental illnesses, as well as the desire of technology to design machines that are able to change their performance according to a person's emotional states, the study of electroencephalography (EEG) signals to analyze the different dimensions of human emotions has become increasingly significant. Based on machine learning models, this study was designed to identify the five emotions of relaxation, happiness, motivation, sadness and fear using EEG signal analysis. EEG data were collected from 23 male master's students at Tabriz University, aged 24–31, as they watched five videos designed to elicit different emotional responses. After preprocessing to remove noise and artifacts, we extracted statistical and frequency-domain features from the raw signal. The features were labeled and selected using statistical tests. In the final step, five different emotions were classified using decision tree, linear discriminant analysis (LDA), Naive Bayes, support vector machine (SVM), K-nearest neighbor (KNN), ensemble, logistic regression and neural network. It has been verified that ensemble and decision tree models had the highest accuracy with 95.38% and 91.77%.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 3","pages":"347-363"},"PeriodicalIF":0.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epigenetic regulation in cognitive impairment: Focus on N6-methyladenosine modification and its potential role in perioperative neurocognitive disorders 认知障碍的表观遗传调控：n6 -甲基腺苷修饰及其在围手术期神经认知障碍中的潜在作用

Ibrain Pub Date : 2025-09-11 DOI: 10.1002/ibra.70000

Ting Liu, Xiao-Juan Yang, Lin Zhou, Mi Gan, Ting-Ting He, Sen Hong, Yan-Yan Feng, Gao Su, You-Xiao Zhao, Ying Cao, Qing-Fan Zeng

{"title":"Epigenetic regulation in cognitive impairment: Focus on N6-methyladenosine modification and its potential role in perioperative neurocognitive disorders","authors":"Ting Liu, Xiao-Juan Yang, Lin Zhou, Mi Gan, Ting-Ting He, Sen Hong, Yan-Yan Feng, Gao Su, You-Xiao Zhao, Ying Cao, Qing-Fan Zeng","doi":"10.1002/ibra.70000","DOIUrl":"https://doi.org/10.1002/ibra.70000","url":null,"abstract":"N6-methyladenosine (m6A), the most abundant internal modification in mammalian mRNA, plays a critical role in cognitive function by dynamically regulating gene expression. This narrative review examines m6A's role in cognitive processes and its potential impact on perioperative neurocognitive disorders (PNDs), which encompass a spectrum including postoperative delirium, delayed neurocognitive recovery, and postoperative cognitive dysfunction. The m6A regulatory machinery—comprising methyltransferases (“writers”), demethylases (“erasers”), and recognition proteins (“readers”)—modulates neuronal development, synaptic plasticity, and cognitive processes by influencing mRNA stability, translation, and degradation. Evidence from animal models indicates that m6A dysregulation contributes to neuroinflammation, neurodegeneration, and neuronal injury, which are pathophysiological mechanisms implicated in PNDs. Notably, anesthetic agents and surgical stress have been shown to alter hippocampal m6A levels, and manipulation of m6A-related proteins may ameliorate cognitive deficits. While these findings suggest potential mechanistic connections, direct evidence specifically linking m6A modifications to PNDs pathogenesis remains preliminary and largely based on preclinical models. Further research is needed to establish causal relationships, identify m6A-modified targets relevant to PNDs pathology, and evaluate m6A as a potential biomarker or therapeutic target. This review provides a foundation for understanding how m6A modification may influence perioperative cognitive outcomes and identifies promising avenues for future investigation.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 3","pages":"332-346"},"PeriodicalIF":0.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.70000","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic parallels between borderline and bipolar patients in psychopathology: Similarities, differences, comorbidities, neural correlates, and a new proposal for the Perrotta Border-Bipolar Profile Diagnostic Questionnaire 边缘型人格障碍和双相情感障碍患者在精神病理学上的诊断相似之处：相似点、差异、合并症、神经相关性，以及对Perrotta边缘型人格障碍诊断问卷的新建议

Ibrain Pub Date : 2025-09-02 DOI: 10.1002/ibra.70001

Giulio Perrotta, Simona Grilli, Stefano Eleuteri, Irene Petruccelli

引用次数: 0

Histological investigation of the interthalamic adhesion and periventricular region: Evidence for midline neural connectivity 丘脑间粘连和心室周围区域的组织学研究：中线神经连通性的证据

Ibrain Pub Date : 2025-06-13 DOI: 10.1002/ibra.12200

Nicole van Heerden, Lané Prigge, Gerda Venter

{"title":"Histological investigation of the interthalamic adhesion and periventricular region: Evidence for midline neural connectivity","authors":"Nicole van Heerden, Lané Prigge, Gerda Venter","doi":"10.1002/ibra.12200","DOIUrl":"https://doi.org/10.1002/ibra.12200","url":null,"abstract":"The interthalamic adhesion (IA), which may not be present in all humans, is a midline structure that connects the two thalami within the brain's third ventricle. A review of the known literature regarding the IA shows few histological studies and controversy regarding the organization of neurons within this region. This study conducted an anatomical investigation of the human IA in adult South African samples. Samples were obtained from 20 human adult embalmed cadavers: 11 from brains with a visible IA and 9 from brains without this feature. All the samples were harvested using sagittal sections of the area. Three additional samples were sectioned horizontally, yielding 33 tissue blocks. Before observation, these samples were appropriately processed for light microscopy and stained with haematoxylin and eosin, as well as cresyl violet. The results showed that no specific structural arrangements of the neurons were identifiable. The appearance appeared random, except for a distinguishable range in the frequency and dispersion of specific cells upon basic observation. Microglia were the most abundant cell type, and blood vessels were also observed. This study reports a novel inspection of the general histology of the thalamus, specifically of the IA and the periventricular (PVR) region, in midsagittal sections and three horizontal sections. This study confirmed the presence of pyramidal neurons within the IA, forming a bridge between the PVR region of the thalami, thus providing evidence to suggest that the IA could serve as a potential bridge for neural connections crossing over the brain's midline.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 3","pages":"375-384"},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12200","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunomodulatory natural polysaccharide-based nanoparticles for the treatment of neurodegenerative diseases 用于治疗神经退行性疾病的免疫调节天然多糖纳米颗粒

Ibrain Pub Date : 2025-05-12 DOI: 10.1002/ibra.12199

Leto-Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis

{"title":"Immunomodulatory natural polysaccharide-based nanoparticles for the treatment of neurodegenerative diseases","authors":"Leto-Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis","doi":"10.1002/ibra.12199","DOIUrl":"https://doi.org/10.1002/ibra.12199","url":null,"abstract":"Polysaccharide-based nanoparticles offer significant potential for the treatment of neurodegenerative diseases and the modulation of inflammatory responses in the central nervous system. These biopolymers, when derived from natural sources, possess inherent immunomodulatory properties, which can be leveraged to regulate immune activity, positioning them as promising candidates for both prophylactic and therapeutic strategies. Furthermore, when integrated with other materials, polysaccharides form nanocomposites with enhanced structural, physicochemical, and biological properties, making them highly versatile platforms for drug delivery in the central nervous system. This review provides a comprehensive analysis of polysaccharide-based nanoparticles, focusing on their application in the treatment of three major neurodegenerative diseases: Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Emphasis is placed on optimizing these nanomaterials for targeted drug delivery and immune modulation, underscoring their potential to improve therapeutic outcomes in neurodegenerative disorders. The review also examines the structural, chemical, and biological characteristics of key polysaccharides, and explores their innovative roles in combating neuroinflammation and neurodegeneration.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 3","pages":"277-296"},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanotechnology in brain cancer treatment: The role of gold nanoparticles as therapeutic enhancers 纳米技术在脑癌治疗中的作用：金纳米颗粒作为治疗增强剂的作用

Ibrain Pub Date : 2025-05-10 DOI: 10.1002/ibra.12198

Simona Tarantino, Annalisa Bianco, Valeria De Matteis, Edoardo Scarpa, Rosaria Rinaldi

{"title":"Nanotechnology in brain cancer treatment: The role of gold nanoparticles as therapeutic enhancers","authors":"Simona Tarantino, Annalisa Bianco, Valeria De Matteis, Edoardo Scarpa, Rosaria Rinaldi","doi":"10.1002/ibra.12198","DOIUrl":"https://doi.org/10.1002/ibra.12198","url":null,"abstract":"Brain cancer, with glioblastoma (GBM) being one of the most aggressive and treatment-resistant cancers, represents a leading cause of mortality and morbidity worldwide. Its complex nature and the presence of the blood-brain barrier (BBB) significantly hinder the effectiveness of conventional therapies, posing major challenges for treatment development. In this context, nanotechnology—particularly nanomedicine—has emerged as a promising strategy to overcome these barriers and enhance standard treatments like chemotherapy and radiotherapy (RT). This review focuses on three of the most challenging brain neoplasms—GBM, brain metastases, and pediatric brain tumors—and explores the growing role of nanoparticle-based therapies, with special emphasis on gold nanoparticles (AuNPs). Owing to their unique physicochemical properties, such as surface functionalization, biocompatibility, and the ability to cross the BBB, AuNPs have shown great potential in selectively delivering drugs, enhancing RT as radiosensitizers, and reducing systemic toxicity. Despite their therapeutic advantages, concerns remain regarding the long-term safety of AuNPs. Their small size and ability to cross biological barriers may lead to unintended biodistribution, immune responses, and cytotoxic effects. Reported risks include inflammatory reactions, apoptosis, and developmental toxicity, highlighting the need for comprehensive safety assessments. AuNPs offer a promising avenue for improving therapeutic efficacy and patient survival in brain cancers. However, their clinical application requires further in-depth preclinical and clinical evaluation to ensure both effectiveness and safety","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 2","pages":"119-145"},"PeriodicalIF":0.0,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions 阿尔茨海默病的治疗前景：当前策略和未来方向

Ibrain Pub Date : 2025-05-10 DOI: 10.1002/ibra.12197

Tapas Kumar Mohapatra, Reena Rani Nayak, Ankit Ganeshpurkar, Prashant Tiwari, Dileep Kumar

{"title":"Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions","authors":"Tapas Kumar Mohapatra, Reena Rani Nayak, Ankit Ganeshpurkar, Prashant Tiwari, Dileep Kumar","doi":"10.1002/ibra.12197","DOIUrl":"https://doi.org/10.1002/ibra.12197","url":null,"abstract":"Alzheimer's disease (AD), a neurodegenerative disease leading to dementia, lacks a single definitive diagnosis. While current medications only manage symptoms, the ideal treatment would restore cognition. Traditional therapies targeting beta-amyloid haven't yielded significant results, while new approaches target tau protein tangles, protein degradation pathways, inflammation, and neurotrophic factor depletion. Autophagy, a cellular degradation and recycling process, has emerged as a crucial hallmark and contributor to the pathogenesis of AD. Notably, autophagy induction has emerged as a promising therapeutic approach, with inducers like celastrol and caudatin promoting the degradation of toxic protein aggregates. Additionally, innovative drug formulations, such as nanoparticles, are being explored for targeted drug delivery. Research is increasingly focusing on neuroinflammation and developing multi-targeted drugs to address various aspects of AD, potentially leading to preventive strategies in the early stages. This review summarizes the current state and emerging trends in AD drug development.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 2","pages":"162-184"},"PeriodicalIF":0.0,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12197","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The rise of 3D bioprinting advancements in modeling neurodegenerative diseases 3D生物打印在神经退行性疾病建模方面的进步

Ibrain Pub Date : 2025-04-22 DOI: 10.1002/ibra.12196

Lucia Iafrate, Gianluca Cidonio

{"title":"The rise of 3D bioprinting advancements in modeling neurodegenerative diseases","authors":"Lucia Iafrate, Gianluca Cidonio","doi":"10.1002/ibra.12196","DOIUrl":"https://doi.org/10.1002/ibra.12196","url":null,"abstract":"Neurodegenerative diseases (NDs) are disorders that drastically alter the physiological functioning of neurons in the brain. These processes are often accompanied by abnormal protein aggregates that alter the physical and chemical properties of brain tissue and peripheral nerves. The causes of NDs are complex, involving genetic factors, neuroinflammation, oxidative stress, environmental influences, and lifestyle, while symptoms and progression vary significantly based on the mechanisms of cell death. Currently, no definitive treatment exists for NDs, as the underlying degenerative processes remain poorly understood. Existing therapies focus on symptom alleviation but are insufficient to halt or prevent disease progression. This highlights the urgent need for strategies that mimic the pathophysiology of NDs, facilitating deeper insights and the development of effective treatments. Conventional in vitro and in vivo models attempt to replicate NDs but often fail to capture the physiological complexity of nervous tissue and its interactions. In this context, 3D microfluidic bioprinting emerges as a transformative technology. By enabling precise deposition of cells and biomaterials, it allows the creation of in vitro models with a high degree of structural and functional complexity. These advancements provide a valuable platform for faithfully modeling NDs, bridging critical gaps in our understanding, and paving the way toward innovative therapeutic approaches.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 2","pages":"259-267"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12196","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prefrontal cortex iron content in neurodegeneration and healthy subjects: A systematic review 神经退行性疾病和健康受试者的前额叶皮层铁含量：系统综述

Ibrain Pub Date : 2025-04-10 DOI: 10.1002/ibra.12195

Sana Mohammadi, Sadegh Ghaderi, Masoud Hoseini Pourasl, Farzad Fatehi

{"title":"Prefrontal cortex iron content in neurodegeneration and healthy subjects: A systematic review","authors":"Sana Mohammadi, Sadegh Ghaderi, Masoud Hoseini Pourasl, Farzad Fatehi","doi":"10.1002/ibra.12195","DOIUrl":"https://doi.org/10.1002/ibra.12195","url":null,"abstract":"Iron accumulation in the prefrontal cortex (PFC) has been implicated in neurodegeneration and cognitive decline. Magnetic resonance imaging (MRI) enables noninvasive quantification of brain iron content and deposition. This review aimed to summarize the evidence on the MRI-based assessment of PFC iron accumulation in healthy individuals and patients with neurodegeneration. A systematic preliminary literature review was conducted using the PubMed, Scopus, Web of Science, and Embase databases. MRI techniques for capturing susceptibility changes reflecting iron, such as susceptibility-weighted imaging (SWI), quantitative susceptibility mapping (QSM), and R2* mapping, were included. Data were extracted, and narrative synthesis was performed. Twelve studies that measured PFC iron levels using MRI in diseases with neurodegeneration (five studies) and healthy subjects (seven studies) were included. In general, studies involving diseases with neurodegeneration have found that increased PFC iron content correlates with cognitive impairment. Aging studies on healthy subjects have reported that age-related accumulation of PFC iron, particularly in the dorsolateral, medial, and anterior subregions, increases with age, and is associated with reduced dopamine signaling and poorer cognition. MRI techniques, such as QSM, can quantify prefrontal iron accumulation in diseases with neurodegeneration and aging. As imaging biomarkers, increased prefrontal iron levels may contribute to neurodegeneration and cognitive decline. Longitudinal studies combining advanced QSM and other advanced neuroimaging techniques with cognitive assessments may further elucidate the effects of iron dysregulation on PFC function. Thus, our findings highlight the importance of MRI as a sensitive tool for assessing PFC iron content and its potential role in understanding the pathogenesis of neurodegeneration and the effects of aging on the brain.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 2","pages":"215-227"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mapping the landscape of brain stimulation research: A global scientometric review on cognitive impairment 绘制脑刺激研究的图景：认知障碍的全球科学计量学综述

Ibrain Pub Date : 2025-03-22 DOI: 10.1002/ibra.12194

Mani Abdul Karim

{"title":"Mapping the landscape of brain stimulation research: A global scientometric review on cognitive impairment","authors":"Mani Abdul Karim","doi":"10.1002/ibra.12194","DOIUrl":"https://doi.org/10.1002/ibra.12194","url":null,"abstract":"Several noninvasive brain stimulation techniques have gained significant attention in neurocognitive science and clinical research due to their potential efficacy in addressing neurological, psychiatric, and cognitive impairments. This study explores global trends and research hotspots in brain stimulation research for cognitive impairment and related disorders. Using a data set from 1989 to 2024 sourced from the Web of Science Core Collection, 4156 records were analyzed through bibliometric methods, including publication trends, country or region, and institutional analysis, and document co-citation analysis (DCA). Results revealed a steady increase in research, with a significant increase in publications during the period from 2019 to 2023. The USA led in citation counts (1117), centrality (0.37), while China topped the burst value (72.31). The University of London led in citation counts (235), whereas Capital Medical University topped the sigma value (1.77). Transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS) dominated the top positions in DCA analysis. Emerging trends were identified through burst keywords, including “transcranial Doppler,” “subthalamic nucleus stimulation,” “cerebral blood flow,” “vascular dementia,” and “cardiopulmonary bypass.” These emerging research hotspots underscore the growing focus on vascular aspects of cognitive impairment and advanced brain stimulation methods. Additionally, newer noninvasive techniques like fast gamma magnetic stimulation, paired-associative stimulation with TMS (PAS-TMS), and theta-burst stimulation are identified as promising avenues for future research, offering significant potential for therapeutic advancements. This study provides a comprehensive overview of the global landscape, trends, and future directions in brain stimulation research for cognitive impairment.","PeriodicalId":94030,"journal":{"name":"Ibrain","volume":"11 2","pages":"185-204"},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ibra.12194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0