Hemodialysis international. International Symposium on Home Hemodialysis最新文献

{"title":"Three Dimensional Speckle Tracking Echocardiography in Hemodialysis Patients.","authors":"Serap Yadigar, Gülümser Sevgin Halil, Pınar Özdemir, Erman Özdemir, Ezgi Gültekin Güner, Abdurrahman Engin Demir, Sukru Hakan Gunduz, Banu Şahin Yıldız, Mustafa Yıldız","doi":"10.1111/hdi.13272","DOIUrl":"https://doi.org/10.1111/hdi.13272","url":null,"abstract":"<p><strong>Background: </strong>It has been suggested that ventricular strain measurements may be impaired in chronic hemodialysis patients despite having no history of heart disease. The aim of this study is to investigate whether ventricular strain parameters can be used to detect subclinical cardiac dysfunction in hemodialysis patients.</p><p><strong>Methods: </strong>In our study, 47 patients under the age of 65 years with no known history of cardiac or valvular disease and receiving chronic hemodialysis treatment for at least 1 year were compared with an age- and sex-matched control group of 29 healthy individuals. Transthoracic echocardiography was used to evaluate parameters such as global longitudinal strain, right ventricular global longitudinal strain, and left ventricular diastolic diameter. Differences between groups were analyzed by Student's t-test and Mann-Whitney U test.</p><p><strong>Results: </strong>The global longitudinal strain values of the hemodialysis group were significantly lower than those of the control group (-13.2 ± 3.91 vs. -22.1 ± 1.59, p < 0.001). Right ventricular global longitudinal strain (RV GLS) and left ventricular diastolic diameter were also significantly impaired in the hemodialysis group (p < 0.05). These results indicate the presence of subclinical cardiac dysfunction in hemodialysis patients.</p><p><strong>Conclusions: </strong>Ventricular strain measurements may be impaired in chronic hemodialysis patients without a history of cardiovascular disease. Therefore, it is considered that ventricular strain measurements can be a useful method for the early detection of cardiac dysfunction in hemodialysis patients.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Dialysis Review: Reducing Water, Energy, and Waste.","authors":"Kyle J Backston, Cole J Thompson, Manya Raina, Nafees R Sathik, Lydia S Noh, Pooja P Lokkur, Shyam B Bansal","doi":"10.1111/hdi.13251","DOIUrl":"https://doi.org/10.1111/hdi.13251","url":null,"abstract":"<p><strong>Background: </strong>Hemodialysis is a lifesaving therapy but imposes a significant environmental burden due to its excessive consumption of water and energy and the generation of non-recyclable medical waste. The emerging Green Dialysis movement aims to mitigate these environmental impacts by promoting sustainable practices in nephrology. We summarize current knowledge on the environmental challenges associated with hemodialysis and highlight innovative strategies for reducing its ecological footprint through the Green Dialysis framework.</p><p><strong>Methods: </strong>This review synthesized recent literature on water use, energy consumption, and waste generation in dialysis, evaluating practical and technological innovations, including water recycling, reduced dialysate flow, renewable energy integration, and sorbent-based systems, that aim to improve sustainability in nephrology care.</p><p><strong>Results: </strong>Key environmental challenges of hemodialysis include excessive water and energy consumption and substantial waste generation. Hemodialysis facilities consume vast quantities of water, with up to 60 percent of treated water being discarded, while energy demands produce considerable carbon emissions. Waste production, particularly plastic waste, poses additional environmental challenges, as much of it is non-recyclable and poorly managed. Through the Green Dialysis movement, there is a concerted effort to promote sustainable practices in nephrology. Innovative solutions such as water recycling, reduced dialysate flow rates, adoption of renewable energy sources, and advanced hemodialysis machine designs may minimize resource use and waste.</p><p><strong>Conclusion: </strong>The Green Dialysis movement offers a comprehensive and actionable approach to improving the environmental sustainability of dialysis care. By integrating these strategies, the Green Dialysis movement aims to mitigate the environmental footprint of hemodialysis, fostering a sustainable and resilient future for nephrology care.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Hemorrhagic Rectal Ulcer in a Uremic Patient: A Case Report and Literature Review.","authors":"Dongdong Liu, Xingbing Han, Min Li, Lingyan Li, Yi Huang, Jingmei Song","doi":"10.1111/hdi.13273","DOIUrl":"https://doi.org/10.1111/hdi.13273","url":null,"abstract":"<p><strong>Background: </strong>Acute hemorrhagic rectal ulcer (AHU) is a rare but severe cause of painless lower GI bleeding, mainly in elderly patients with comorbidities. Uremia increases bleeding risk due to platelet dysfunction and hemodialysis anticoagulation, but AHU in dialysis patients is underreported.</p><p><strong>Aims: </strong>To report a case of AHU in a uremic hemodialysis patient and analyze management challenges.</p><p><strong>Materials and methods: </strong>A 78-year-old female with ESRD presented with rectal bleeding. Colonoscopy showed a 3 × 4 cm ulcer, managed with clips, injections, and adhesives.</p><p><strong>Results: </strong>The patient experienced recurrent bleeding, requiring multiple endoscopic interventions (titanium clip placement, methylene blue-polydocanol injection, tissue adhesive). Despite initial hemostasis, she developed worsening heart failure and multi-organ failure, dying at home after ICU admission.</p><p><strong>Discussion: </strong>Uremia, anticoagulation, and comorbidities fueled bleeding. Endoscopic therapy was key, but systemic decline dominated. Multidisciplinary care is vital for high-risk patients.</p><p><strong>Conclusion: </strong>This case instills awareness of the exigency regarding continuous observation and tailored management in this population of patients with high risk.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Artificial Intelligence in Scientific Writing. The Danger of Trying Too Hard to Please.","authors":"John T Daugirdas","doi":"10.1111/hdi.13270","DOIUrl":"https://doi.org/10.1111/hdi.13270","url":null,"abstract":"<p><p>The author describes his experience using several artificial intelligence programs to assist in the process of editing or preparing manuscripts for publication. While the programs were very useful to increase clarity and optimize the English of previously written text, problems arose when asked to review the literature to describe or expand on concepts, and then to cite references to support those statements. Citations were sometimes fabricated. The artificial intelligence program would even provide PubMed identification (PMID) numbers for references cited, which sometimes pointed to completely different publications. In references that were correctly cited, a request to extract data from their abstracts yielded data that were completely fabricated or incorrect. The newer versions of these artificial intelligence programs appear to be enormously helpful in helping with the process of scientific writing, but one needs to assiduously verify every statement made with regard to their interpretation of the medical literature and double-check any citations by retrieving and reading those references. Because statements made by these agents are proffered with great confidence and using excellent writing skills, the resulting errors can be difficult to anticipate. The motivations behind such errors are unknown, but appear to be related to a desire of AI to please the user at any cost. Programmers who create these tools somehow managed to allow such errors, and this issue must be addressed in future versions of AI. Also, it would help greatly if AI had access to the full text of medical scientific articles, which might be achieved by contractual agreements with the main medical publishers.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Distress in Hemodialysis: Impact of Life Events, Illness Perception, and Difficulty Processing Emotions (Alexithymia).","authors":"Weihuan Sun, Yanshuang Chang","doi":"10.1111/hdi.13269","DOIUrl":"https://doi.org/10.1111/hdi.13269","url":null,"abstract":"<p><strong>Background: </strong>Depression and anxiety in individuals undergoing hemodialysis (HD) significantly impair daily functioning and hinder renal rehabilitation efforts. Various factors, including negative life events, illness perceptions, and difficulty processing emotions (alexithymia), have been associated with these psychological challenges; however, their specific impact on HD-related psychological distress remains unclear.</p><p><strong>Methods: </strong>In this cross-sectional study, 246 individuals receiving HD were assessed using self-administered questionnaires, including the Life Events Scale (LES), Illness Perceptions Questionnaire (IPQ-R), Toronto Alexithymia Scale (TAS-20), and the Hospital Anxiety and Depression Scale (HADS).</p><p><strong>Results: </strong>The study found that 32.5% and 41.5% of HD patients exhibited symptoms of depression and anxiety, respectively. Logistic regression analyses revealed significant correlations between negative life events, illness perceptions, and alexithymia with both depression and anxiety. Specifically, higher scores on the \"Negative Emotional Representation about Illness\" subscale were associated with an increased risk of depression (adjusted odds ratio [OR], 1.302; 95% confidence interval [CI], 1.118-1.544; p < 0.001). Conversely, lower scores on \"Personal Control\" were linked to a heightened risk of depression (adjusted OR, 0.796; 95% CI, 0.683-0.927; p = 0.003). For anxiety, elevated scores in \"Negative Emotional Representation about Illness\" (adjusted OR, 1.185; 95% CI, 1.014-1.261; p = 0.015) and \"difficulty identifying feelings\" (adjusted OR, 1.210; 95% CI, 1.031-1.411; p = 0.016) indicated increased risk, while lower scores in \"Personal Control\" were similarly associated with heightened anxiety risk (adjusted OR, 0.852; 95% CI, 0.734-0.983; p = 0.042).</p><p><strong>Conclusion: </strong>This study suggests that negative life events, specific illness perceptions, and alexithymia are significant predictors of depression and anxiety among HD patients. Addressing maladaptive illness perceptions and emotional regulation deficits could offer novel strategies to enhance mental health outcomes in this population, highlighting the need for further investigation.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Thirst Perception on Health-Related Quality of Life in Hemodialysis Patients: A Multicenter Study.","authors":"Jyana G Morais, Murilo Guedes, Ana B Barra, John W Larkin, Maria E F Canziani, Roberto Pecoits-Filho, Fabiana B Nerbass","doi":"10.1111/hdi.13271","DOIUrl":"https://doi.org/10.1111/hdi.13271","url":null,"abstract":"<p><strong>Introduction: </strong>Thirst distress is a common yet underexplored symptom among hemodialysis (HD) patients, with limited understanding of its impact on quality of life. This study aims to evaluate thirst perception, identify factors associated with its intensity, and examine its relationship with quality of life in a multicenter cohort of HD patients.</p><p><strong>Methods: </strong>This cross-sectional analysis utilized baseline data from the Hemodiafiltration on Physical Activity and Self-Reported Outcomes: A Randomized Controlled Trial (HDFit). Participants were over 18 years old from 13 dialysis units across Brazil. Thirst perception was assessed using the Dialysis Thirst Inventory (DTI) questionnaire, and health-related quality of life (HRQoL) was measured with the SF-36 questionnaire. We compared participants with low versus high thirst perception based on the median DTI score and conducted multiple regression analysis to identify independent determinants of physical and mental HRQoL components.</p><p><strong>Findings: </strong>The study sample comprised 195 patients (male: 71%; median age: 54 [41-66] years; 29% with diabetes) from 13 dialysis centers, with chronic HD duration up to 24 months. The median DTI score was 17 (14-22). Participants with higher thirst perception (DTI > 17) were younger, had a higher prevalence of lower income and educational levels, and a lower prevalence of fluid overload. Multiple regression analysis, adjusted for demographic, clinical, and nutritional variables, revealed that increased thirst perception was independently associated with poorer physical and mental HRQoL.</p><p><strong>Conclusion: </strong>In a multicenter HD population, higher thirst perception was an independent determinant of diminished health-related quality of life.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid Nodule Incidence, Characteristics, and Localization in Hemodialysis Patients With End-Stage Renal Disease: A Cross-Sectional Study in Palestine.","authors":"Firas K Fohely, Ammar A Oglat, Mousa M Shaheen, Sema I Athamnah, Raed Al Saeed, Sami A Makharza, Kamel M Jebrin, Haneen Nur, Hussein ALMasri","doi":"10.1111/hdi.13268","DOIUrl":"https://doi.org/10.1111/hdi.13268","url":null,"abstract":"<p><strong>Background: </strong>Patients with end-stage kidney disease (ESKD) undergoing hemodialysis frequently exhibit thyroid dysfunction or morphological abnormalities such as thyroid nodules. Although prior studies indicate a high prevalence of thyroid abnormalities in ESKD patients, few have explored the specific incidence, types, and anatomical distribution of thyroid nodules in this population.</p><p><strong>Purpose: </strong>This study aimed to determine the prevalence, types, and anatomical distribution of thyroid nodules in ESKD patients on hemodialysis and to evaluate the relationship between hemodialysis duration and nodule occurrence.</p><p><strong>Methods: </strong>A cross-sectional study was conducted at Beit Jala Hospital, Palestine, involving 200 ESKD patients receiving hemodialysis. Thyroid ultrasound was used to assess nodule presence, morphology, and distribution. Patient demographics, medical history, and dialysis duration were analyzed using statistical methods.</p><p><strong>Results: </strong>Thyroid nodules were identified in 41.0% (n = 82) of participants, with no significant gender differences (p = 0.839). Solid nodules (58.5%) were more prevalent than cystic nodules (41.4%), and unilateral multinodular goiter (60.5%) was more common than bilateral multinodular goiter (39.5%), though these differences were not statistically significant. A significant correlation was observed between hemodialysis duration and nodule prevalence, with a higher incidence in patients on dialysis for ≥ 5 years (p = 0.003), suggesting prolonged dialysis may contribute to nodule formation.</p><p><strong>Conclusion: </strong>This study confirms a high prevalence of thyroid nodules in ESKD patients on hemodialysis, predominantly solid nodules, and unilateral multinodular goiter. The significant association between longer dialysis duration and increased nodule prevalence highlights the need for routine thyroid monitoring in this population. Further research is needed to elucidate underlying mechanisms and optimize clinical management of thyroid abnormalities in ESKD patients.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Function Tests to Assess Postural Balance in Patients on Dialysis: A Systematic Review.","authors":"Luciana A S Jesus, Bruno V Pinheiro, Emanuele P L Gravina, Carlos M B Silva, Gabriela F Paticcié, Pelagia Koufaki, Leda M F Lucinda, Cristino C Oliveira, Maycon M Reboredo","doi":"10.1111/hdi.13263","DOIUrl":"https://doi.org/10.1111/hdi.13263","url":null,"abstract":"<p><strong>Background: </strong>This systematic review evaluated physical function tests used to assess postural balance in patients on dialysis and described their measurement properties.</p><p><strong>Methods: </strong>The study was registered in PROSPERO (#CRD42020186578). Seven databases were searched from inception to August 2023. Observational and experimental studies including at least one physical function test for postural balance in patients on hemodialysis or peritoneal dialysis were eligible. Two independent researchers selected studies, assessed methodological quality using the Critical Review Form-Quantitative Studies, and extracted data.</p><p><strong>Results: </strong>Of the 21 studies analyzed, 42.9% were cross-sectional, and 38.1% demonstrated good methodological quality. The one-leg standing Test was the most common physical function test (used in 47.6% of studies), with variations in protocol, such as eyes open or closed and durations ranging from 5 to 60 s or unspecified. Other tests included the Berg balance scale, balance evaluation systems test, brief-balance evaluation systems test, mini-balance evaluation systems test, stork balance test, standing balance test, functional reach test, and frailty and injuries cooperative studies of intervention technique-4. Reliability, standard error of measurement, and minimal detectable change were reported for only the one-leg standing test, balance evaluation systems test, brief-balance evaluation systems test, and mini-balance evaluation systems test.</p><p><strong>Conclusions: </strong>The one-leg standing test was the most frequently used physical function test for assessing postural balance in patients on dialysis. Additionally, the measurement properties of these tests remain understudied in this population.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Listening to an Audiobook on Anxiety, Depression, and Quality of Life in Patients Receiving Hemodialysis: A Randomized Controlled Trial.","authors":"Sevgi Demir Çam, Elanur Yılmaz Karabulutlu","doi":"10.1111/hdi.13250","DOIUrl":"https://doi.org/10.1111/hdi.13250","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to assess the impact of audiobooks on anxiety, depression, and quality of life in patients undergoing hemodialysis.</p><p><strong>Methods: </strong>We conducted a randomized controlled trial involving 60 patients receiving hemodialysis. The intervention group listened to audiobooks for 4 weeks. Data on anxiety and depression levels were collected using the Hospital Anxiety and Depression Scale, and quality of life was assessed using the SF-36 Quality of Life Scale.</p><p><strong>Results: </strong>Statistically significant reductions in anxiety and depression scores were observed in the intervention group following the 4-week audiobook intervention. Furthermore, the intervention group demonstrated significant improvements in quality of life parameters, specifically in energy, social functioning, physical role limitations, and mental health. The control group showed a significant improvement only in social functioning.</p><p><strong>Conclusions: </strong>The findings suggest that audiobook interventions can effectively reduce anxiety and depression and enhance certain aspects of quality of life in patients receiving hemodialysis.</p><p><strong>Trial registration: </strong>Registration number: NCT05272891.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcome Analysis of Peritoneal Dialysis and Hemodialysis in Patients With End-Stage Kidney Disease: A Real-World Data Analysis.","authors":"Yi-Hsien Chen, Yun-Yi Chen, Yu-Wei Fang, Hung-Hsiang Liou, Jing-Tong Wang, Ming-Hsien Tsai","doi":"10.1111/hdi.13267","DOIUrl":"https://doi.org/10.1111/hdi.13267","url":null,"abstract":"<p><strong>Background: </strong>Despite extensive research on peritoneal dialysis (PD) and hemodialysis (HD), understanding long-term outcomes between these modalities remains limited. We conducted a retrospective cohort study to assess the clinical outcomes of PD and HD in a real-world context.</p><p><strong>Methods: </strong>Utilizing the National Health Insurance Research Database in Taiwan, we studied patients who underwent dialysis from January 2006 to December 2017. Patients with a history of cancer, renal transplantation, age < 20 or > 84 years, or patients on PD who switched to HD within 3 months of starting the modality were excluded. They were categorized into three groups: HD-only (n = 59,751), PD-only (n = 3969), and PD-to-HD transition (n = 3196). Propensity score matching based on sex, age, and the Charlson comorbidity index was used to create comparable groups. Hazard ratios (HR) for clinical outcomes were calculated using the Cox regression model, comparing HD-only versus PD-only and the transition group outcomes. Follow-up continued until December 31, 2020. Finally, external validation was performed using the global TriNetX dataset.</p><p><strong>Results: </strong>After 1:1 propensity score matching and multivariable adjustment, the HD-only group (n = 3969) exhibited significantly lower all-cause mortality and infection-related admissions compared to the PD-only group (n = 3969) (HRs 0.77 and 0.75, 95% CI: 0.72-0.83 and 0.70-0.80, respectively), with a survival advantage across most subgroups. Conversely, the PD-to-HD transition group (n = 2014) had worse hospitalization and major adverse cardiovascular event outcomes than those on PD-only (n = 2014) (HRs 1.83 and 1.22, 95% CIs: 1.71-1.97 and 1.10-1.36, respectively) but showed neutral mortality rates. A survival benefit emerged 2 years post-transition from PD to HD, with an HR of 0.62 (95% CI: 0.54-0.74). These findings were corroborated by the TriNetX data.</p><p><strong>Conclusion: </strong>Our study indicates that HD patients tend to have better clinical outcomes, including greater longevity, compared to PD patients. Thus, the choice of dialysis modality should be tailored to individual patient needs for optimal outcomes.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}