Hand surgery & rehabilitation最新文献

{"title":"Biomechanical comparison of scapholunate reconstruction techniques in a type II wrist model.","authors":"M T Alonso-Rasgado, R Leonardo-Diaz, D Jimenez-Cruz, C G Bailey, S Talwalkar","doi":"10.1016/j.hansur.2026.102759","DOIUrl":"10.1016/j.hansur.2026.102759","url":null,"abstract":"<p><strong>Background: </strong>This study assesses the biomechanical changes following scapholunate interosseous ligament rupture and subsequent surgical reconstruction in a single-subject type II wrist, utilising cadaveric-validated finite element models.</p><p><strong>Methods: </strong>The type II native wrist model was used to simulate scapholunate interosseous ligament rupture alongside three reconstruction techniques, Modified Brunelli, Corella, and Scapholunate Axis Method, across four distinct wrist motions. Wrist stability was assessed through scapholunate gap and angle, contact area, and multidirectional carpal kinematics.</p><p><strong>Results: </strong>Scapholunate interosseous ligament rupture caused scaphoid-lunate contact loss, altered carpal rotational mechanics, and increased dorsal/volar scapholunate gaps and angles. The Modified Brunelli Technique demonstrated the closest restoration of normal carpal biomechanics after scapholunate rupture, more effectively restoring scaphoid, lunate, and triquetral rotation, successfully re-establishing scapholunate articular contact, producing a joint contact pattern that more closely resembled the intact joint pattern. Our findings demonstrate that scapholunate interosseous ligament rupture causes less instability in type II wrists than in type I wrists. The additional hamate facet in type II wrists promotes column mechanics and midcarpal stiffness, keeping kinematics closer to the intact state. The superior performance of the Modified Brunelli Technique in the type II wrist stems from its unique graft configuration, which aligns with the wrist's distinct column mechanics.</p><p><strong>Conclusions: </strong>Following simulation of a scapholunate interosseous ligament rupture in a type II wrist, the Modified Brunelli Technique demonstrated the closest restoration of native kinematics, comparatively to the Corella and Scapholunate Axis Method procedures. The current study provides a platform upon which future work is planned, including evaluating a broader range of wrists to compare surgical techniques and identify optimal approaches for specific wrist types.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102759"},"PeriodicalIF":1.0,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148803530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional thumb carpometacarpal joint motion during activities of daily living: A three-dimensional kinematic analysis.","authors":"Chihiro Fujime, Riko Sumioka","doi":"10.1016/j.hansur.2026.102758","DOIUrl":"10.1016/j.hansur.2026.102758","url":null,"abstract":"<p><strong>Background: </strong>Task-specific three-dimensional data describing thumb carpometacarpal (CMC)-related kinematics during activities of daily living remain limited.</p><p><strong>Purpose: </strong>To describe thumb CMC-related kinematics during standardized functional tasks in healthy young adults using high-frequency magnetic tracking.</p><p><strong>Study design: </strong>Cross-sectional descriptive study.</p><p><strong>Methods: </strong>In 11 healthy young adults, thumb CMC-related motion was recorded during 11 standardized tasks corresponding to the hand-function domain of the Thumb Disability Exam. Radial-ulnar motion, palmar-dorsal motion, and opposition-related axial rotation were summarized within each participant for each task and axis, and task-specific descriptive values were calculated across participant-level summaries.</p><p><strong>Results: </strong>The functional tasks demonstrated distinct kinematic profiles. Tasks involving manipulation, rotation, or bimanual object handling, including using a knife, opening a jar, buttoning a shirt/blouse, tying shoelaces, and wringing a dishcloth/washcloth, showed larger angular excursions than tasks involving more static holding or precision positioning. Descriptive heat maps showed commonly observed angular regions within the processed dataset, but these patterns were interpreted descriptively because the time-series samples were not independent participant-level observations.</p><p><strong>Conclusions: </strong>This study provides preliminary descriptive data on three-dimensional thumb CMC-related kinematics during standardized activities of daily living in healthy young adults. The findings suggest that thumb motion requirements differ across functional tasks. Further validation in larger, older, and clinical populations is required before these data can be applied to orthotic design, surgical planning, or rehabilitation goal setting.</p><p><strong>Clinical relevance: </strong>These preliminary findings describe task-specific thumb CMC-related motion during activities of daily living and may contribute to future research on thumb biomechanics, functional assessment, and clinical intervention planning after further validation.</p><p><strong>Level of evidence: </strong>Diagnostic Level III.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102758"},"PeriodicalIF":1.0,"publicationDate":"2026-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148698702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perineural vascular network of the deep branch of the radial nerve following methylene blue injection: an anatomical study.","authors":"Thomas Yvonnet, Nicolas Bigorre, Marie Loisel, Thomas Daoulas","doi":"10.1016/j.hansur.2026.102757","DOIUrl":"10.1016/j.hansur.2026.102757","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to determine the anterior or posterior predominance of the methylene-blue-stained perineural vascular network surrounding the deep branch of the radial nerve (DBRN).</p><p><strong>Methods: </strong>An anatomical study was conducted on ten elbows from five fresh-frozen donor bodies following low-flow methylene blue injection into the brachial artery. The methylene-blue-stained perineural vascular network surrounding the DBRN within the supinator muscle was observed and classified into three groups: posterior to the nerve, mixed, or anterior. The distribution of the stained network along the nerve was analyzed, as well as the morphology of the tendinous arch of the supinator muscle and the superficial layer of the supinator muscle.</p><p><strong>Results: </strong>Ten elbows were dissected. Fifty percent showed a posterior staining pattern (Group 1), 20% a mixed pattern (Group 2), and 30% an anterior pattern (Group 3). The stained network was concentrated proximally in 40% of cases, extended along the entire intramuscular course of the nerve within the supinator muscle in 40%, and was limited to the distal portion in 20%. The tendinous arch of the supinator muscle was tendinous in 40%, musculotendinous in 40%, and purely muscular in 20% of cases. The superficial layer of the supinator was musculotendinous in 60% and purely muscular in 40%.</p><p><strong>Conclusions: </strong>This descriptive anatomical study showed that the DBRN is surrounded by a methylene-blue-stained perineural vascular network with substantial interindividual variability. Given the limitations inherent to the injection technique, these findings should be interpreted as preliminary observations rather than a definitive characterization of the vascularization of the DBRN. Their clinical implications will need to be confirmed by further studies.</p><p><strong>Level of evidence: </strong>V Cadaveric Anatomical Study.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102757"},"PeriodicalIF":1.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface landmark-based estimation of the posterior interosseous nerve: A cadaveric anatomical study.","authors":"Navita Aggarwal, Rajesh Maurya, Vandana Tiwari, Akhilesh Pathak, Priti Chaudhary","doi":"10.1016/j.hansur.2026.102756","DOIUrl":"10.1016/j.hansur.2026.102756","url":null,"abstract":"<p><strong>Background: </strong>The posterior interosseous nerve (PIN) is a motor branch of the radial nerve. It is particularly vulnerable to compression as it passes through the supinator muscle, especially at the arcade of Frohse. Most anatomical studies describe its course using fixed distances from deep landmarks, such as the radial head, which limits clinical applicability due to interindividual variation in limb dimensions. Therefore, a surface-landmark-based, ratio-driven approach may provide a practical and reproducible method for localising the PIN in surgical settings.</p><p><strong>Methods: </strong>In this study, upper limbs from 15 adult cadavers were dissected. With the forearm in pronation, the lateral epicondyle to radial styloid line (LR line; distance a) and the lateral epicondyle to a point 1 cm radial to ulnar styloid (LU line; distance b) were marked as surface reference lines. The PIN was identified between the brachioradialis and extensor carpi radialis longus muscles, and distances from the lateral epicondyle to its entry (c) and exit (d) points from the supinator were measured, along with the intramuscular travel length (Tr). Ratios a/c and b/d were calculated.</p><p><strong>Results: </strong>Mean distances were:a 24.54 cm, b 22.82 cm, c 4.26 cm, d 8.54 cm, and Tr 5.83 cm. The mean a/c and b/d ratios were 5.76 and 2.67, respectively. PIN entry and exit points are consistently projected near the LR and LU lines.</p><p><strong>Conclusion: </strong>Ratio-based surface mapping is a practical technique for estimating PIN location in forearm peripheral nerve surgeries. However, additional validation in actual patients is needed.</p><p><strong>Level of evidence: </strong>V (Cadaveric anatomical study).</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102756"},"PeriodicalIF":1.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTED: Artificial Intelligence in Osteoarthritis Diagnosis and Treatment: Advancements, Challenges, and Future Prospects.","authors":"Saumya Awasthi, Prafulla Chandra Tiwari, Srishti Awasthi, Arpit Dwivedi, Shikha Srivastava","doi":"10.1016/j.hansur.2026.102587","DOIUrl":"10.1016/j.hansur.2026.102587","url":null,"abstract":"<p><p>Osteoarthritis (OA) is a leading cause of disability, with diagnosis and management limited by inter-observer variability and the absence of individualized therapeutic strategies. This review critically examines recent applications of artificial intelligence (AI) in OA diagnosis, treatment planning, rehabilitation, and drug discovery, with a particular focus on clinically relevant imaging-based and predictive models. We synthesize evidence from radiographic and MRI-based AI systems used for disease grading, progression prediction, and surgical outcome forecasting, highlighting their performance, limitations, and translational barriers. Particular emphasis is placed on how AI-generated outputs can inform clinical decision-making, including treatment selection and rehabilitation monitoring. Current challenges related to dataset bias, external validation, and workflow integration are discussed using concrete examples from published studies. Finally, we outline future directions aimed at improving clinical utility through explainable AI, multi-modal data integration, and prospective validation. This focused synthesis underscores both the promise and the practical constraints of AI-driven osteoarthritis care.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":"102587"},"PeriodicalIF":1.0,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential CpG methylation at <i>Nnat</i> in the early establishment of beta cell heterogeneity.","authors":"Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S Varghese, Pauline Chabosseau, Sayed M Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis, Lorella Marselli, Carmela De Luca, Marta Tesi, Giada Ostinelli, Luis Delgadillo-Silva, Xiwei Wu, Yuki Hatanaka, Alex Montoya, James Elliott, Bhavik Patel, Nikita Demchenko, Chad Whilding, Petra Hajkova, Pavel Shliaha, Holger Kramer, Yusuf Ali, Piero Marchetti, Robert Sladek, Sangeeta Dhawan, Dominic J Withers, Guy A Rutter, Steven J Millership","doi":"10.1101/2023.02.04.527050","DOIUrl":"10.1101/2023.02.04.527050","url":null,"abstract":"<p><strong>Aims/hypothesis: </strong>Beta cells within the pancreatic islet represent a heterogenous population wherein individual sub-groups of cells make distinct contributions to the overall control of insulin secretion. These include a subpopulation of highly-connected 'hub' cells, important for the propagation of intercellular Ca²⁺ waves. Functional subpopulations have also been demonstrated in human beta cells, with an altered subtype distribution apparent in type 2 diabetes. At present, the molecular mechanisms through which beta cell hierarchy is established are poorly understood. Changes at the level of the epigenome provide one such possibility which we explore here by focussing on the imprinted gene neuronatin (<i>Nnat</i>), which is required for normal insulin synthesis and secretion.</p><p><strong>Methods: </strong>Single cell RNA-seq datasets were examined using Seurat 4.0 and ClusterProfiler running under R. Transgenic mice expressing eGFP under the control of the <i>Nnat</i> enhancer/promoter regions were generated for fluorescence-activated cell (FAC) sorting of beta cells and downstream analysis of CpG methylation by bisulphite and RNA sequencing, respectively. Animals deleted for the de novo methyltransferase, DNMT3A from the pancreatic progenitor stage were used to explore control of promoter methylation. Proteomics was performed using affinity purification mass spectrometry and Ca²⁺ dynamics explored by rapid confocal imaging of Cal-520 and Cal-590. Insulin secretion was measured using Homogeneous Time Resolved Fluorescence Imaging.</p><p><strong>Results: </strong><i>Nnat</i> mRNA was differentially expressed in a discrete beta cell population in a developmental stage- and DNA methylation (DNMT3A)-dependent manner. Thus, pseudo-time analysis of embryonic data sets demonstrated the early establishment of <i>Nnat</i>-positive and negative subpopulations during embryogenesis. NNAT expression is also restricted to a subset of beta cells across the human islet that is maintained throughout adult life. NNAT⁺ beta cells also displayed a discrete transcriptome at adult stages, representing a sub-population specialised for insulin production, reminiscent of recently-described \"β_HI\" cells and were diminished in <i>db/db</i> mice. 'Hub' cells were less abundant in the NNAT⁺ population, consistent with epigenetic control of this functional specialization.</p><p><strong>Conclusions/interpretation: </strong>These findings demonstrate that differential DNA methylation at <i>Nnat</i> represents a novel means through which beta cell heterogeneity is established during development. We therefore hypothesise that changes in methylation at this locus may thus contribute to a loss of beta cell hierarchy and connectivity, potentially contributing to defective insulin secretion in some forms of diabetes.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10705251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82487063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of the mallet fracture: Open or percutaneous procedure?","authors":"G. Caruso, Laura Martini, S. Sargenti, A. Vitali","doi":"10.1016/j.hansur.2022.09.102","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.102","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43226124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intérêt de l’arthroscopie du poignet dans la prise en charge du syndrome d’Essex Lopresti au stade aigu","authors":"G. Herzberg, M. Burnier, Lyliane Ly","doi":"10.1016/j.hansur.2022.09.110","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.110","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41610827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conception d’une prothèse de pouce mixte, thermoformée et impression 3D pour les patients amputés","authors":"V. Oca, Maxime Debailleul, Charles Hustin, P. Duriez, d’Almeida Marc-Antoine, P. Laronde","doi":"10.1016/j.hansur.2022.09.233","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.233","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45250410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparaison de l’auto-évaluation et évaluation dans l’apprentissage de la microchirurgie: Une étude rétrospective comparative dans une cohorte d’étudiants en microchirurgie","authors":"J. Brunet, A. Petit, J. Jeudy, E. Maugendre, Y. S. Cast, N. Bigorre","doi":"10.1016/j.hansur.2022.09.152","DOIUrl":"https://doi.org/10.1016/j.hansur.2022.09.152","url":null,"abstract":"","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48023535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}