Enfermeria intensiva最新文献

{"title":"Severity classification and influencing variables of the Postintensive Care Syndrome","authors":"M.A. Narváez-Martínez ,&nbsp;Á.M. Henao-Castaño","doi":"10.1016/j.enfie.2023.07.005","DOIUrl":"10.1016/j.enfie.2023.07.005","url":null,"abstract":"<div><h3>Objective</h3><p>The study aims to characterise Postintensive Care Syndrome by classifying the severity of the disease and identifying the variables of influence in two highly complex intensive care units for adults in Colombia.</p></div><div><h3>Methods</h3><p>A descriptive, cross-sectional, prospective study was carried out to characterise survivors of critical illness<span> using the Healthy Aging<span> Brain Care –Monitor in a sample of 135 patients. Postintensive Care Syndrome severity was classified using Gaussian Mixture Models for clustering, and the most influencing variables were identified through ordinal logistic regression.</span></span></p></div><div><h3>Results</h3><p>Clustering based on Gaussian Mixture Models allowed the classification of Postintensive Care Syndrome severity into mild, moderate, and severe classes, with an Akaike Information Criterion of 308 and an area under the curve<span> of 0.80, which indicates a good fit; Thus, the mild class was characterised by a score on the HABC-M Total scale ≤9; the moderate class for a HABC-M Total score ≥10 and ≤42 and the severe class for a HABC-M Total score ≥43. Regarding the most influencing variables, the probability of belonging to the moderate or severe classes was related to male sex (91%), APACHE II score (22.5%), age (13%), intensive care units days of stay (10.6%), the use of sedation, analgesia<span> and neuromuscular blockers.</span></span></p></div><div><h3>Conclusion</h3><p>Intensive care units survivors were characterised using the Healthy Aging Brain Care–Monitor scale, which made it possible to classify Postintensive Care Syndrome through Gaussian Mixture Models clustering into mild, moderate, and severe and to identify variables that had the major influence on the presentation of Postintensive Care Syndrome.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 2","pages":"Pages 89-96"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9894524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation and validation of the Turkish version of the alarm fatigue assessment questionnaire","authors":"Öznur Erbay-Dallı RN, MSc, PhD ,&nbsp;Kübra Bağcı-Derinpınar RN, MSc","doi":"10.1016/j.enfie.2023.09.001","DOIUrl":"10.1016/j.enfie.2023.09.001","url":null,"abstract":"<div><h3>Objective</h3><p>Alarm fatigue may endanger the safety of patients by negatively affecting nurses' concentration and ability to provide effective care. Identifying alarm fatigue and taking appropriate measures are critical in preventing medical errors and for nurses to work with high motivation. This study aimed to test the psychometric properties of the Turkish version of the 23-item Alarm Fatigue Assessment Questionnaire (AFAQ).</p></div><div><h3>Method</h3><p><span>The study was conducted between February 2022 and April 2022 and included nurses with at least one year of clinical or intensive care<span> experience. The data were collected via a web-based questionnaire. During the adaptation of AFAQ, language, content, and construct validity were evaluated; reliability was examined by </span></span>internal consistency analysis.</p></div><div><h3>Results</h3><p><span>The item and scale content validity index of AFAQ were found to be high (&gt;0.80). The Kaiser–Meyer–Olkin measure of sampling adequacy indicated an adequate sampling (0.85); Bartlett's test of sphericity χ</span>² was 1935.074, p<!--> <!-->&lt;<!--> <span>0.001. Exploratory factor analysis<span> (EFA) showed that the 21-item scale had a five-factor structure, explaining 51.606% of the total variance, and the factor loadings of the items were &gt;0.30 (0.422−0.803). Confirmatory factor analysis (CFA) showed that the five-factor model had a good fit index (χ</span></span>²/df<!--> <!-->=<!--> <!-->1.855, SRMR<!--> <!-->=<!--> <!-->0.039, RMSEA<!--> <!-->=<!--> <!-->0.048, CFI<!--> <!-->=<!--> <!-->0.915, and TLI<!--> <!-->=<!--> <!-->0.908) and appropriate factor loadings (&gt;0.30). The internal consistency of AFAQ (Cronbach's alpha coefficient) was 0.85, and the corrected item-total correlations were between 0.32−0.55.</p></div><div><h3>Conclusion</h3><p>The results indicated that the Turkish version of the Alarm Fatigue Assessment Questionnaire was sufficiently valid and reliable to measure alarm fatigue in nurses.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 2","pages":"Pages 114-123"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41170890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of closed blood sampling systems in intensive care patients: a scoping review","authors":"M. Raurell-Torredà PhD, MSN, RN ,&nbsp;S. Arias-Rivera PhDc, MSN, RN ,&nbsp;M.E. Rodríguez-Delgado RN, MsC ,&nbsp;C. Campos-Asensio BPharm, MLS ,&nbsp;R.-J. Fernández-Castillo PhDc, MSN, RN","doi":"10.1016/j.enfie.2023.05.001","DOIUrl":"10.1016/j.enfie.2023.05.001","url":null,"abstract":"<div><h3>Background</h3><p><span>Anemia associated with blood extraction for diagnostic purposes is a highly prevalent entity in </span>intensive care units (ICU) for adults. The evidence recommends its prevention through different strategies, among which we can find the use of closed blood sampling systems (CBSS). Different experimental studies support the use of these devices.</p></div><div><h3>Objective</h3><p>To identify knowledge gaps regarding the effectiveness of CBSS in ICU patients.</p></div><div><h3>Methods</h3><p>Scoping review with search in PubMed, CINAHL<span><span>, Embase, </span>Cochrane Library and Joanna Briggs Institute databases, between September-2021 and September-2022. No time, language, or other limits were applied to ensure the recovery of all relevant studies. Gray literature sources: DART-Europe, OpenGrey and Google Scholar. Two researchers independently reviewed titles and abstracts and assessed full texts against the inclusion criteria. The following data was extracted for each study: design and sample, inclusion and exclusion criteria, variables, type of CBSS, results and conclusions.</span></p></div><div><h3>Results</h3><p>18 articles were included in the final review, 11 clinical trials (RCTs) published between 1992 and 2014. Three systematic reviews<span><span> were found, but they only analyzed the effect of CBSS in reducing blood loss, hemoglobin stabilization, and the need for transfusion. Five of the RCTs analyzed the risk of infection, one </span>catheter complications, and two alterations in blood pressure readings.</span></p></div><div><h3>Conclusions</h3><p><span>The use of CBSS is recommended to reduce blood loss in ICUs. However, there are discrepancies about their ability to prevent anemia and/or the need for blood transfusion. Its use does not increase catheter-related infection rates or alter the measurement of </span>mean arterial pressure.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 2","pages":"Pages 133-145"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9761060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not all frail patients are elderly","authors":"Federico Gordo-Vidal","doi":"10.1016/j.enfie.2024.05.002","DOIUrl":"https://doi.org/10.1016/j.enfie.2024.05.002","url":null,"abstract":"","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 2","pages":"Pages 77-78"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-pharmacological interventions to reduce physical restraints in critical care units","authors":"G. Via-Clavero ,&nbsp;M. Acevedo Nuevo ,&nbsp;D. Gil-Castillejos ,&nbsp;J.J. Rodríguez Mondéjar ,&nbsp;D. Alonso Crespo","doi":"10.1016/j.enfie.2023.11.002","DOIUrl":"10.1016/j.enfie.2023.11.002","url":null,"abstract":"<div><p>Physical restraint use in critical care units is a frequent low-value care practice influenced by numerous factors creating a local culture. The translation of evidence-based recommendations into clinical practice is scarce so, the analysis of interventions to de-adopt this practice is needed. This update aims to describe and identify nonpharmacological interventions that contribute to minimising the use of physical restraints in adult critically ill patients. Interventions are classified into two groups: those that include education alone and those that combine training with one or more components (multicomponent interventions). These components include less restrictive restraint alternatives, use of physical and cognitive stimulation, decision support tools, institutional multidisciplinary committees, and team involvement. The heterogeneity in the design of the programmes and the low quality of the evidence of the interventions do not allow us to establish recommendations on their effectiveness. However, multicomponent interventions including training, physical and cognitive stimulation of the patient and a culture change of professionals and the organisations towards making restraints visible might be the most effective. The implementation of these programmes should underpin on a prior analysis of each local context to design the most effective-tailored combination of interventions to help reduce or eliminate them from clinical practice.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 2","pages":"Pages e8-e16"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140069023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurses’ perceptions of the obstacles and supportive behaviors of end-of-life care in intensive care units","authors":"Majd T. Mrayyan ,&nbsp;Nijmeh Al-Atiyyat ,&nbsp;Ala Ashour ,&nbsp;Ali Alshraifeen ,&nbsp;Abdullah Algunmeeyn ,&nbsp;Sami Al-Rawashdeh ,&nbsp;Murad Sawalha ,&nbsp;Abdallah Abu Khait ,&nbsp;Imad Alfayoumi ,&nbsp;Mohammad Sayaheen ,&nbsp;Mohammad Odeh","doi":"10.1016/j.enfie.2023.04.001","DOIUrl":"10.1016/j.enfie.2023.04.001","url":null,"abstract":"<div><h3>Purpose</h3><p>This study examined the Jordanian registered nurses’ perceptions of the obstacles and supportive behaviors of End-of-Life Care in Intensive Care Units and examined the differences in the concepts based on the samples’ demographics.</p></div><div><h3>Methods</h3><p><span>A cross-sectional and comparative study was conducted using a convenience sample of 230 Intensive Care Unit registered nurses in Jordan. Data were analyzed descriptively, and differences were measured using the independent sample </span><em>t</em><span>-test, the one-way Analysis of Variance, and Scheffe’s post hoc test.</span></p></div><div><h3>Results</h3><p>The registered nurses’ scored moderately on obstacles (74.98 ± 14.54) and supportive behaviors (69.22 ± 4.84). The commonly perceived obstacle and supportive behaviors to End-of-Life Care in Intensive Care Units s were reported. The perceived obstacles differ based on the registered nurses’ certification as an Intensive Care Units nurse (3.04 ± 0.58 vs. 2.74 ± 0.49, p = 0.008), type of Intensive Care Unit (3.28 ± 0.34 vs. 2.86 ± 0.62, p &lt; 0.001), type of facility (3.16 ± 0.59 vs. 2.77 ± 0.61, p &lt; 0.001), number of beds in the unit (3.07 ± 0.48 vs. 2.69 ± 0.48, p = 0.020), and the number of hours worked per week (3.06 ± 0.56 vs. 2.81 ± 0.60, p = 0.005). In contrast, supportive behaviors only differ based on the registered nurses’ age (3.22 ± 0.69 vs. 2.90 ± 0.64, p = 0.019).</p></div><div><h3>Conclusions</h3><p>The common End-of-Life Care perceived obstacle in Intensive Care Units was the lack of nursing education and training regarding the studies concept, which warrants immediate intervention such as on-job training. The common End-of-Life Care perceived supportive behavior in Intensive Care Units was when family members accepted that the patient was dying when nurses offered support to family members; motivational interventions are needed to sustain such behavior. Differences in the perceived obstacles and supportive behaviors should be leveraged for the benefit of patients, nurses, and hospitals.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 1","pages":"Pages 23-34"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41175559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to “Do we actively and early mobilize patients admitted to an intensive care unit during mechanical ventilation?”","authors":"G. Ballesteros-Reviriego PT, MSc ,&nbsp;J. Daniel Martí PT, PhD ,&nbsp;B. Planas-Pascual PT, MSc","doi":"10.1016/j.enfie.2023.06.002","DOIUrl":"10.1016/j.enfie.2023.06.002","url":null,"abstract":"","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 1","pages":"Pages 74-75"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72212272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the implementation of a standardised interdisciplinary information transfer method in the delivery room and intermediate obstetric care unit","authors":"E. Crespo-Mirasol RN, RM, MSc, PhD ,&nbsp;A. Llupià-García MD, MSc, PhD ,&nbsp;J. Bellart-Alfonso MD, MSc, PhD ,&nbsp;A. Peguero-Yus MD, MSc, PhD ,&nbsp;F. Figueras-Retuerta MD, MSc, PhD ,&nbsp;A.S. Hernández-Aguado MD, MSc, PhD","doi":"10.1016/j.enfie.2023.07.002","DOIUrl":"10.1016/j.enfie.2023.07.002","url":null,"abstract":"<div><h3>Aim</h3><p>This study aims to describe the implementation of the standard methodology for information transfer in the labour ward and Intermediate Obstetric Care Unit and to identify the impact of this implementation on the factors that act as facilitators and barriers in the procedure.</p></div><div><h3>Method</h3><p><span>Quasi-experimental pretest-posttest study without a control group in an Intermediate Obstetric Care Unit and delivery room of the Maternal-Fetal Medicine Service of a tertiary hospital in Barcelona. Healthcare staff self-completed an </span><em>ad hoc</em> questionnaire before and after implementing the standardised IDEAS methodology in the service during 2019 and 2020. Personal self-perception in the information transfer procedure was assessed. The Wilcoxon pairwise test was used for comparison before and after.</p></div><div><h3>Results</h3><p>The use of a standardised methodology has shown an impact on improving the transmission of information. Significant differences were detected before and after the intervention in the following dimensions: location, people involved, time period of the procedure, structured, orderly and clear, and sufficient time for questions (p &lt; 0.001); while no differences were observed in: transmission to the referring professional, well-defined actions, and completion of a summary.</p></div><div><h3>Conclusions</h3><p>There are factors such as structural and organisational aspects and lack of time that hinder effective communication and therefore act as barriers to the transfer of information. The implementation of a methodology with the health professionals involved, the time and the appropriate space allows for the improvement of communication aspects in the multiprofessional team and, therefore, patient safety.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 1","pages":"Pages 5-12"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10027141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood glucose monitoring in critically ill adult patients: type of sample and method of analysis. Systematic review and meta-analysis","authors":"S. Arias-Rivera PhDc, MSN, RN ,&nbsp;M. Raurell-Torredà PhD, MSN, RN ,&nbsp;R.-J. Fernández-Castillo PhDc, MSN, RN ,&nbsp;C. Campos-Asensio BPharm, MLS ,&nbsp;I.-J. Thuissard-Vasallo MsC, PhD ,&nbsp;C. Andreu-Vázquez PhD, MsC, MvD ,&nbsp;M.E. Rodríguez-Delgado MsC, RN","doi":"10.1016/j.enfie.2023.02.002","DOIUrl":"10.1016/j.enfie.2023.02.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The clinical guideline for the management of sepsis, recommends using arterial blood samples for glycaemic control. A multicentre study in 86 Spanish intensive care units (ICU) revealed that 85.4% of ICUs used capillary puncture.</p></div><div><h3>Objective</h3><p>To analyse the reliability of glycaemia by comparing different blood samples (arterial, venous, capillary) and instruments (glucometers, gasometers, central laboratory). Secondarily, to estimate the effect of confounding variables and the performance of measuring instruments as determined by different quality standards.</p></div><div><h3>Methodology</h3><p>Systematic review and meta-analysis with search in PubMed, CINAHL and Embase databases in September-2021 and September-2022, with no time or language limits. Grey literature sources: DART-Europe, OpenGrey and Google Scholar. Results summarised by qualitative (description of results, study characteristics) and quantitative (meta-analysis to assess standardised mean difference) synthesis. Methodological quality of articles assessed with Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). Protocol: <span>https://osf.io/</span><svg><path></path></svg> DOI 10.17605/OSF.IO/T8KYP.</p></div><div><h3>Results</h3><p>A total of 32 articles and 5451 patients were included. No discrepancies were obtained between arterial glucometer vs laboratory samples [bias (95%CI): 0.01 (−0.12 to 0.14) mg/dL]. In contrast, arterial samples with a gasometer did significantly overestimate [bias (95%CI): 0.12 (0.01 to 0.24) mg/dL]. The same trend is seen in capillaries with a glucometer, although not significantly [bias (95%CI): 0.07 (-−0.02 to 0.15) mg/dL]. There is discrepancy between studies on the effect of haematocrit and acid-base balance. The greatest consensus is on the poor agreement of glucometer with capillary vs laboratory samples in the presence of shock and vasopressor support, renal failure or during vitamin C treatment.</p></div><div><h3>Conclusions</h3><p>The evidence to date recommends the use of arterial blood with a blood glucose meter for better reliability of glycaemic analysis and less effect of possible confounding variables, frequently present in the critically ill adult patient.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 1","pages":"Pages 45-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2529984023000344/pdfft?md5=071cbe5c78a6fc3d6a86cceb4cd88c32&pid=1-s2.0-S2529984023000344-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9845755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of a hyperoxygenated fatty acid compound in improving the microcirculation of purpura fulminans in paediatric patients with sepsis: a pilot study","authors":"G. Pérez-Acevedo RN, PNP, MSc, PhD ,&nbsp;A. Bosch-Alcaraz PhD, RN, PNP, MSc ,&nbsp;J.E. Torra-Bou PhD, RN, MSc","doi":"10.1016/j.enfie.2023.07.003","DOIUrl":"10.1016/j.enfie.2023.07.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Purpura fulminans (PF) is a serious complication of sepsis resulting from a set of alterations characterised by the development of ecchymotic haemorrhagic lesions and skin necrosis.</p></div><div><h3>Aim</h3><p>To analyse the efficacy and safety of the topical application of HOFA compound, in the cutaneous microcirculation of PF lesions in paediatric patients affected by sepsis.</p></div><div><h3>Material and methods</h3><p>A prospective quasi-experimental pre-test/post-test single-group conducted in a Paediatric Intensive Care Unit of a third level hospital was performed. Paediatric patients aged 0–18 years with sepsis were included. Somatic oximetry values were measured before and after application of HOFAs every 4<!--> <!-->h over the first three days of the patients’ hospitalisation. Patient’s socio-demographic and clinical variables and somatic oximetry by placing a sensor for measuring tissue perfusion on the area with PF were determined.</p></div><div><h3>Results</h3><p>Four patients were recruited, with a median age of 98 months. The purpuric lesions measured were mainly located on both feet and hands and, in two patients, also on the lateral malleoli and calves of both lower extremities. A total of 225 measurements were obtained, with mean pre-intervention scores of 71.17<!--> <!-->±<!--> <!-->15.65% versus 73.68<!--> <!-->±<!--> <!-->14.83% post-intervention. Statistical significance (p<!--> <!-->&lt;<!--> <!-->0.001) was observed upon comparison of the pre- and post-intervention measurements.</p></div><div><h3>Conclusions</h3><p>Early and continued application of HOFAs in the management of sepsis-induced PF is an effective and safe practice in the cases analysed. In more than half of the episodes analysed, an increase in tissue microcirculation was observed after the application of HOFAs, with no adverse events.</p></div>","PeriodicalId":93991,"journal":{"name":"Enfermeria intensiva","volume":"35 1","pages":"Pages 13-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S252998402300040X/pdfft?md5=fa89b2cc1b9f733faeb5f7039974db36&pid=1-s2.0-S252998402300040X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10277669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}