Dermatitis : contact, atopic, occupational, drug最新文献_第10页

Cutaneous Granulomatous Reaction Secondary to Mesotherapy. 继发于中胚层疗法的皮肤肉芽肿反应

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-11-01 Epub Date: 2024-05-23 DOI: 10.1089/derm.2023.0358

Shrishti Singh, Sakshi Sitaniya, Aayush Gupta

引用次数: 0

Nonsteroidal Approaches for Atopic Dermatitis®: A Clinical Update. 治疗特应性皮炎的非类固醇疗法：临床更新。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-11-01 Epub Date: 2024-02-06 DOI: 10.1089/derm.2023.0373

Peter Y Ch'en, Peter A Lio

引用次数: 0

Impact of Atopic Dermatitis® on Quality of Life of Caregivers: A Systematic Review and Meta-Analysis. 特应性皮炎对护理人员生活质量的影响：系统回顾与元分析》。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-11-01 Epub Date: 2024-02-16 DOI: 10.1089/derm.2023.0362

John Chun Hian Yap, Yik Weng Yew

{"title":"Impact of Atopic Dermatitis® on Quality of Life of Caregivers: A Systematic Review and Meta-Analysis.","authors":"John Chun Hian Yap, Yik Weng Yew","doi":"10.1089/derm.2023.0362","DOIUrl":"10.1089/derm.2023.0362","url":null,"abstract":"Abstracts: Background: Atopic Dermatitis® (AD) is a chronic dermatological condition that affects both patients and their caregivers. Aims: To summarize evidence on the impact of AD on the quality of life (QoL) of caregiver. Methods: Observational studies were searched for in Medline, Embase, Cochrane Library, SCOPUS, and CINAHL databases up till March 1, 2023. Results: Seventy studies with a total of 33,291 study participants were identified. The Dermatitis® Family Index (DFI) questionnaire featured in 29 studies and was chosen for further meta-analysis. The pooled DFI for all studies was 9.35 (95% confidence interval [CI] 6.94-11.76). For individual components, the highest component scores were for 1.24 for expenditure (95% CI 0.80-1.69), followed by 1.14 for emotions (95% CI 0.77-1.50), as well as sleep 1.12 (95% CI 0.71-1.54) and exhaustion 1.12 (95% CI 0.76-1.48). Meta-analysis on the effect of patient QoL on family QoL was conducted on 15 studies, with a pooled Spearman's rank coefficient using Infants' Dermatitis® Quality of Life Index (IDQoL) was 0.632 (95% CI 0.558-0.707), whereas that using Children's Dermatology Life Quality Index (CDLQI) was 0.624 (95% CI 0.507-0.741). For the 17 studies correlating AD severity with family QoL, a pooled Spearman's rank coefficient of 0.425 (95% CI 0.330-0.521) was obtained. Conclusions: AD is associated with significant negative impacts on caregiver QoL, particularly in family finance, caregiver burnout, and sleep impairment. This was consistently affected by AD severity and patient QoL in all studies examining this association.","PeriodicalId":93974,"journal":{"name":"Dermatitis : contact, atopic, occupational, drug","volume":" ","pages":"554-595"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139747879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Clinical Phenotype of Patients with Contact Polysensitization, a Retrospective Cohort. 接触性多致敏症患者的临床表型，回顾性队列。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-30 DOI: 10.1089/derm.2024.0004

Danny Daniely, Jonathan Bar, Dan Slodownik

{"title":"The Clinical Phenotype of Patients with Contact Polysensitization, a Retrospective Cohort.","authors":"Danny Daniely, Jonathan Bar, Dan Slodownik","doi":"10.1089/derm.2024.0004","DOIUrl":"https://doi.org/10.1089/derm.2024.0004","url":null,"abstract":" Background: Polysensitization, defined as contact sensitization to three or more allergens, is an allergic phenotype with a common genetic background. Our study aims to characterize the clinical features of patients with polysensitization. Methods: We analyzed patch test results of 5,082 patients from a designated contact dermatitis clinic in Tel Aviv between 2012 and 2022 and compared the polysensitized group with nonsensitized and oligosensitized patients, hence patients reacting to 1 or 2 allergens. Results: About 8.5% of patients were polysensitized. In the nonsensitized group, there were significantly fewer female patients and more children (P < 0.05) than in the polysensitized group. Asthma prevalence was linearly associated with the number of positive reactions in patch test. Polysensitized patients were more commonly suffering from hand eczema and an occupational etiology (P < 0.05). Textile dye mix, lyral, fragrance mix II, formaldehyde, colophonium, and p-phenylendiamine were more common sensitizers among the polysensitized group, whereas nickel sulfate, 2-hydroxyethyl methacrylate, fragrance mix 1, p-tert-butylphenol formaldehyde resin, and sodium metabisulfite were more common among the oligosensitized group. Conclusions: The association between polysensitization, asthma prevalence, and sensitization to volatile allergens raises an intriguing clinical phenotype. Further mechanistic studies are needed in this regard.","PeriodicalId":93974,"journal":{"name":"Dermatitis : contact, atopic, occupational, drug","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing Unmet Needs in Atopic Dermatitis: Evaluating Disease-Modifying Capabilities of Current and Emerging Therapies. 满足特应性皮炎未满足的需求：评估现有疗法和新兴疗法的疾病调节能力。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-28 DOI: 10.1089/derm.2024.0261

Sarah G Brooks, Lourdes M Lopez, Kayla D Mashoudy, Gil Yosipovitch, Tali Czarnowicki

{"title":"Addressing Unmet Needs in Atopic Dermatitis: Evaluating Disease-Modifying Capabilities of Current and Emerging Therapies.","authors":"Sarah G Brooks, Lourdes M Lopez, Kayla D Mashoudy, Gil Yosipovitch, Tali Czarnowicki","doi":"10.1089/derm.2024.0261","DOIUrl":"https://doi.org/10.1089/derm.2024.0261","url":null,"abstract":" Atopic dermatitis (AD) is a highly burdensome inflammatory skin condition affecting nearly one-quarter of the pediatric population and often continuing into adulthood. Despite recent advancements in systemic therapies providing temporary symptom relief over the past decade, AD frequently remains difficult to control, necessitating increased dosages or alternative treatments due to recurrent disease. This review synthesizes current literature to identify unmet needs of treating AD beyond medication-related limitations and evaluates existing therapies for their efficacy in modifying underlying disease mechanisms. Key findings include variability in AD pathophysiology and phenotypes across different age groups and ethnicities, indicating a need for research into endotype-specific treatments. The literature also comprises evidence suggesting that select current drugs, such as targeted biologics and Janus Kinase (JAK) inhibitors, may offer long-term disease-modifying benefits. Future management strategies should explore novel approaches, including manipulation of the microbiome, immune response, and neural function, as these may lead to additional improvements in AD treatment and long-term symptom relief.","PeriodicalId":93974,"journal":{"name":"Dermatitis : contact, atopic, occupational, drug","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic Contact Dermatitis from Brimonidine Tartrate Eye Drops: A Rare Dermatological Reaction with a "Teardrop Streak Sign". 酒石酸溴莫尼定滴眼液引起的过敏性接触性皮炎：带有 "泪滴条纹征 "的罕见皮肤病反应。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-24 DOI: 10.1089/derm.2024.0055

Hailey Konisky, A Neal Gregory, Albert Huho

引用次数: 0

Effectiveness and Safety of Upadacitinib in Adolescent and Adult Patients with Atopic Dermatitis: An Analysis of Long-Term (Week 52) Data from a Real-World Multicenter Retrospective Review. 乌达帕替尼对青少年和成人特应性皮炎患者的有效性和安全性：一项真实世界多中心回顾性研究的长期（第52周）数据分析》。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-24 DOI: 10.1089/derm.2024.0208

Brian D Rankin, Siddhartha Sood, Ye-Jean Park, Alexander Rimke, Abrahim Abduelmula, Jorge R Georgakopoulos, Khalad Maliyar, Fernejoy Leung, Lauren A Stark, Alim R Devani, Jensen Yeung, Vimal H Prajapati

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Disseminated Foreign Body Granuloma on the Face Treated with Upadacitinib. 用乌达帕替尼治疗面部播散性异物肉芽肿

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-24 DOI: 10.1089/derm.2024.0352

Jinfa Dou, Hongwei Liu, Chen Wang, Jianguo Li, Jianbo Wang

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Rivaroxaban-Induced Symmetrical Drug-Related Intertriginous and Flexural Exanthema. 利伐沙班诱发与药物相关的对称性三叉神经间和挠性红斑。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-24 DOI: 10.1089/derm.2024.0357

Helena Pires Pereira, Eduardo Silva, Joana Moreira, Isabel Carrapatoso, Ana Todo-Bom

引用次数: 0

The Importance of Pre-Emptive Scarified Patch Testing to Identify Safe, Alternative Ophthalmic Agents: A Case of Phenylephrine Contact Dermatitis. 预防性瘢痕斑贴测试对确定安全的眼科替代药物的重要性：一例苯肾上腺素接触性皮炎病例。

Dermatitis : contact, atopic, occupational, drug Pub Date : 2024-10-21 DOI: 10.1089/derm.2024.0304

Andrew Scheman, Jack Herbster, Madison Wolkov, Lilly Kerchinsky

引用次数: 0