Cirugia espanola最新文献_第7页

Analysis of predictors for complete tumor response after primary systemic therapy in breast cancer 乳腺癌原发性全身治疗后肿瘤完全缓解的预测因素分析。

Cirugia espanola Pub Date : 2025-07-01 DOI: 10.1016/j.cireng.2025.800112

Sonia Martinez Alcaide , Izaskun Balciscueta Coltell , Ricardo Bou Monterde , Maria Jose Enguix Soriano , Pedro Juan Gonzalez Noguera , Francisco Javier Del Pino Porres

{"title":"Analysis of predictors for complete tumor response after primary systemic therapy in breast cancer","authors":"Sonia Martinez Alcaide , Izaskun Balciscueta Coltell , Ricardo Bou Monterde , Maria Jose Enguix Soriano , Pedro Juan Gonzalez Noguera , Francisco Javier Del Pino Porres","doi":"10.1016/j.cireng.2025.800112","DOIUrl":"10.1016/j.cireng.2025.800112","url":null,"abstract":"<div><h3>Introduction</h3><div>Primary systemic therapy in breast cancer is an effective tool for increasing pathological complete response prior to surgery and improving patient survival. The main objective of this study was to analyze the predictive variables for complete tumor response after neoadjuvant therapy.</div></div><div><h3>Methods</h3><div>Data from 146 breast cancer patients treated with primary systemic therapy at La Ribera Hospital between 2018 and 2022 were reviewed. Statistical methods were employed using SPSS 23 software to identify factors predicting tumor response to treatment.</div></div><div><h3>Results</h3><div>Among the patients analyzed, 22.6% presented complete response according to magnetic resonance imaging, and 31.5% showed no residual tumor in the surgical specimen. In the univariate analysis, variables associated with higher presence of residual tumor included lymphovascular invasion (<em>P</em> = 0; 95%CI: 2.361−45.390), luminal B subtype (<em>P</em> = .039; 95%CI: 1.028−5.826), and sentinel node involvement or positive axillary nodes in axillary lymphadenectomy (<em>P</em> = .031; 95%CI: 1.006−72.361). Conversely, tumors smaller than 2 cm (<em>P</em> = .002; 95%CI: 1.567−7.535) and the Her2+ subtype (<em>P</em> = .004; 95%CI: 0.086−0.667) were associated with a higher likelihood of no residual tumor. In the multivariate analysis, lymphovascular invasion was the only statistically significant factor associated with the presence of residual tumor (<em>P</em> = .021; 95%CI: 0.037−0.760).</div></div><div><h3>Conclusions</h3><div>Lymphovascular invasion was identified as a predictor of lack of response to neoadjuvant treatment. Additionally, the Her2+ subtype demonstrated the best response to preoperative therapy. These findings suggest that, to improve therapeutic outcomes, it is crucial to consider these variables when personalizing patient treatment.</div></div>","PeriodicalId":93935,"journal":{"name":"Cirugia espanola","volume":"103 7","pages":"Article 800112"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cirugia espanola Pub Date : 2025-07-01 DOI: 10.1016/j.cireng.2025.800105

Marta Ruiz de la Cuesta , Celia Villodre , Mario Serradilla , Emilio Ruiz de la Cuesta , Cándido Alcazar , José M. Ramia

引用次数: 0

Advantages of the robotic approach for managing late biliary complications in liver transplantation 机器人治疗肝移植晚期胆道并发症的优势。

Cirugia espanola Pub Date : 2025-06-01 DOI: 10.1016/j.cireng.2025.800102

Victor López-López, Pedro Cascales-Campos, Francisco Sánchez-Bueno, Pablo Ramirez, Ricardo Robles-Campos

引用次数: 0

Robotics in rectal cancer: Advantages for surgeons or for patients? 机器人治疗直肠癌：对外科医生有利还是对患者有利？

Cirugia espanola Pub Date : 2025-06-01 DOI: 10.1016/j.cireng.2025.800115

Marcos Gómez Ruiz , Eloy Epin Basany

引用次数: 0

Emergency inguinal hernia surgery: A proposed update to the clinical guidelines algorithm 紧急腹股沟疝手术：临床指南算法的建议更新。

Cirugia espanola Pub Date : 2025-06-01 DOI: 10.1016/j.cireng.2025.800098

Victor Rodrigues-Gonçalves , Mireia Verdaguer-Tremolosa , Alejandro Bravo-Salva , Pilar Martínez-López , José Antonio Pereira-Rodríguez , Manuel López-Cano

{"title":"Emergency inguinal hernia surgery: A proposed update to the clinical guidelines algorithm","authors":"Victor Rodrigues-Gonçalves , Mireia Verdaguer-Tremolosa , Alejandro Bravo-Salva , Pilar Martínez-López , José Antonio Pereira-Rodríguez , Manuel López-Cano","doi":"10.1016/j.cireng.2025.800098","DOIUrl":"10.1016/j.cireng.2025.800098","url":null,"abstract":"<div><h3>Introduction</h3><div>Management strategies for acute irreducible hernias vary, with recent debates on the role of manual reduction versus immediate surgery. This study aimed to identify preoperative risk factors for bowel resection in acute irreducible inguinal hernias.</div></div><div><h3>Methods</h3><div>A retrospective cohort study included patients from 2 university hospitals who underwent emergency surgery for acute irreducible hernias between January 2010 and December 2018.</div></div><div><h3>Results</h3><div>Out of a total of 652 patients, 15% required intestinal resection; females, older individuals, and those with comorbidities were more likely to undergo resection. Multivariate analysis identified patients with femoral hernia (OR 2.272; 95%CI 1.275–4.047; <em>P</em> = .005) and preoperative intestinal obstruction (OR 8.071; 95%CI 4.331–15.043; <em>P</em> < .001). Patients needing resection experienced higher postoperative complication rates and longer hospital stays.</div></div><div><h3>Discussion</h3><div>Femoral hernia and preoperative intestinal obstruction were independent predictors of bowel resection in acute irreducible hernias. Incorporating these factors into decision-making algorithms may improve patient outcomes and optimize surgical management.</div></div>","PeriodicalId":93935,"journal":{"name":"Cirugia espanola","volume":"103 6","pages":"Article 800098"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intestinal obstruction of extraluminal origin 肠腔外源性肠梗阻。

Cirugia espanola Pub Date : 2025-06-01 DOI: 10.1016/j.cireng.2025.800108

Alfonso Serrano García, Antonio Serafín Valero Liñán, José Antonio González Masiá, Belén Conde Inarejos

引用次数: 0

TROPIS is effective in managing complex anal fistulas with additional supralevator rectal opening (ASRO) by Garg phenomenon TROPIS是一种有效的治疗复杂肛瘘与附加的直肠上开口（ASRO） Garg现象。

Cirugia espanola Pub Date : 2025-06-01 DOI: 10.1016/j.cireng.2025.800101

Nicola Clemente , James C.W. Khaw , Yuliya Medkova , Pankaj Garg

引用次数: 0

Response to the Letter to the Editor regarding our article on efficacy one year after the TROPIS Technique for the treatment of complex anal fistula 关于我们关于TROPIS技术治疗复杂肛瘘一年后疗效的文章致编辑的信的回复。

Cirugia espanola Pub Date : 2025-06-01 DOI: 10.1016/j.cireng.2025.800119

Fernando de la Portilla de Juan , María Luisa Reyes Díaz , Fátima Hinojosa Ramirez