Canadian journal of veterinary research = Revue canadienne de recherche veterinaire最新文献_第7页

The effect of an energy additive on the metabolism of cattle. 能量添加剂对牛新陈代谢的影响。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2021-07-01

Elina Nafikova, Irina Mironova, Igor Gazeev, Dmitry Blagov, Azat Nigmatiyanov

{"title":"The effect of an energy additive on the metabolism of cattle.","authors":"Elina Nafikova, Irina Mironova, Igor Gazeev, Dmitry Blagov, Azat Nigmatiyanov","doi":"","DOIUrl":"","url":null,"abstract":"The objective of this study was to determine the effect of an energy additive on the metabolism of cattle. This article provides information on the analysis of the diet of young cattle calculated for when the animals were both indoors and outdoors. The ration was prepared for 40 heifers, divided into 4 groups consisting of 10 animals in each group. Three of these groups were fed different amounts of a high-energy additive, which was not fed to the control group. The effectiveness of the additive was analyzed according to the balance experiment and by calculating digestibility coefficients. It was determined that the percentage of nitrogen use in young animals was higher in the groups that were fed the additive than in the control group. Increasing the dose of the additive increased the level of nitrogen use. Comparative analysis of live weight indicated intergroup differences in favor of heifers in the groups that were fed the additive of 1.34% to 2.41% at the age of 9 mo; 2.51% to 4.16% at 12 mo; 3.14% to 5.46% at 15 mo; and 3.57% to 6.30% at 18 mo. The average daily growth dynamics indicated a gradual increase in all animals up to 15 mo, with a slight decrease by 18 mo of age. The difference among the groups ranged from 5.08% to 8.85% at 6 to 9 mo of age; 7.08% to 10.79% at 9 to 12 mo; 5.64% to 10.97% at 12 to 15 mo; and 6.05% to 11.11% at 18 mo. It was concluded that feeding the energy additive Tanrem to heifers increased their metabolism so that nitrogen use was improved, and feed was digested more efficiently, which in turn improved the growth of animals. Using an energy additive at the mid-range dose of 500 g a day per animal is recommended, since the effect was similar at the mid-range and maximum dosages.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"85 3","pages":"210-217"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243801/pdf/cjvr_03_210.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of naturally occurring asthma with inhaled fluticasone or oral prednisolone: A randomized pilot trial. 吸入氟替卡松或口服泼尼松治疗自然发生的哮喘：一项随机试验。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2021-01-01

Michael Verschoor-Kirss, Elizabeth A Rozanski, Claire R Sharp, Trisha J Oura, Ashley Egan, Perry Bain, Joyce Knoll

{"title":"Treatment of naturally occurring asthma with inhaled fluticasone or oral prednisolone: A randomized pilot trial.","authors":"Michael Verschoor-Kirss, Elizabeth A Rozanski, Claire R Sharp, Trisha J Oura, Ashley Egan, Perry Bain, Joyce Knoll","doi":"","DOIUrl":"","url":null,"abstract":"The objective of this study was to compare inhaled glucocorticoids with oral glucocorticoids for treatment of naturally occurring feline asthma. Secondary goals were to evaluate serum allergy testing results in cats and to quantify the effect of an inhaled glucocorticoid (fluticasone) on glucose homeostasis. Nine cats with asthma were enrolled on the basis of clinical signs, thoracic radiographic findings, and airway eosinophilia. Cats were randomized and 4 cats were treated with oral glucocorticoids and 5 cats with inhaled glucocorticoids, with a 7-day course of oral glucocorticoids overlapping at the start of therapy. Cats were evaluated at baseline and at 8 wk with thoracic radiographs, bronchoalveolar lavage, lung function testing, and fructosamine levels. Serum allergen panels were evaluated. All cats were clinically normal after treatment and had significantly improved airway eosinophilia and decreased nucleated cell count. No improvement was seen in radiographic changes after treatment with either therapy. Oral, but not inhaled glucocorticoids, caused a decrease in airway resistance, although cats in the inhaled group had a higher baseline resistance than those in the oral group. Fructosamine levels did not change with treatment. Fifty percent of cats tested positive for immunoglobulin E (IgE) antibodies. Asthma is a heterogeneous condition; individual cats responded well to both oral and inhaled glucocorticoids. Ongoing evaluation of the potential underlying causes and therapeutic options is warranted with a larger group of cats.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"85 1","pages":"61-67"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747657/pdf/cjvr_01_61.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Duration of immunity after rabies vaccination in dogs: The Rabies Challenge Fund research study. 狂犬病疫苗接种后狗的免疫持续时间：狂犬病挑战基金研究。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2020-04-01

W Jean Dodds, Laurie J Larson, Kris L Christine, Ronald D Schultz

{"title":"Duration of immunity after rabies vaccination in dogs: The Rabies Challenge Fund research study.","authors":"W Jean Dodds, Laurie J Larson, Kris L Christine, Ronald D Schultz","doi":"","DOIUrl":"","url":null,"abstract":"A prospective study of 65 research beagles kept in a rabies-free environment was undertaken to determine the duration of immunity after they received licensed rabies vaccines. The eventual goal was to extend mandated rabies booster intervals to 5 or 7 years and help reduce the risk of vaccine-associated adverse events. Three groups of dogs were vaccinated with 1 of 2 commercial rabies vaccines or saline at 12 and 15 weeks of age. Beginning 5 years 5 months later, vaccinated and unvaccinated dogs were challenged with virulent rabies virus and observed for 90 days over a series of 3 trials. Humoral and cellular immune responses were examined by serology and flow cytometry. Brain tissue from all challenged dogs was tested for rabies virus. Challenge trial 1 was confounded due to insufficiently virulent virus. In trials 2 and 3 virulent challenge provided 100% mortality in controls. Vaccinate survival was 80% (4/5) after 6 years 7 months, 50% (6/12) after 7 years 1 month, and 20% (1/5) after 8years 0 months. Antibody responses 12 days post-challenge correlated strongly with survival. In a separate non-challenge trial, administration of either a recombinant or a killed rabies vaccine demonstrated memory antibody responses 6 years 1 month after initial vaccination compared with unvaccinated controls. Our data demonstrated that i) duration of immunity to rabies in vaccinated dogs extends beyond 3 years; ii) immunologic memory exists even in vaccinated dogs with serum antibody titer < 0.1 IU/mL; and iii) non-adjuvanted recombinant rabies vaccine induces excellent antibody responses in previously vaccinated dogs 14 days after administration.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"84 2","pages":"153-158"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088826/pdf/cjvr_02_153.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41165391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular variability of Streptococcus uberis isolates from intramammary infections in Canadian dairy farms from the Maritime region. 从加拿大滨海地区奶牛场乳房内感染中分离出的尤伯杯链球菌的分子变异性。

IF 0.8

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2019-07-01

Julian Reyes, Juan C Rodriguez-Lecompte, Adam Blanchard, J T McClure, Javier Sánchez

{"title":"Molecular variability of Streptococcus uberis isolates from intramammary infections in Canadian dairy farms from the Maritime region.","authors":"Julian Reyes, Juan C Rodriguez-Lecompte, Adam Blanchard, J T McClure, Javier Sánchez","doi":"","DOIUrl":"","url":null,"abstract":"The primary objective of this study was to explore the variability of Streptococcus uberis (S. uberis) isolates by extracting multilocus sequence typing (MLST) data from whole-genome sequencing. The secondary objective was to determine the distribution of the phenotypic antimicrobial resistance (AMR) and the associated AMR genes as well as the virulence gene profiles among sequence types (STs). Sixty-two isolates were recovered from 16 herds in 3 Canadian Maritime Provinces: New Brunswick (14.5%), Nova Scotia (48.3%), and Prince Edward Island (37.1%). Of these, 9, 30, and 23 were recovered from post-calving, lactational samples, and post-mastitis samples, respectively. These 62 S. uberis isolates belonged to 34 STs; 11 isolates were typed to 9 known STs and 51 isolates were classified as one of 25 new STs. Thirteen isolates were part of major clonal complexes (CCs). Post-mastitis isolates contained 10 unique STs, lactational isolates contained 11 unique STs, and post-calving isolates had 3 STs. Each farm had only 1 isolate that was a unique ST except for STs 233, 851, 855, 857, 864, and 866, which were found in multiple cows per herd on more than one farm. ST851 and ST857 were found in each of the 3 sample types, with ST857 found in cows from all 3 Maritime provinces. These results indicate that S. uberis is a diverse non-clonal pathogen with specific STs residing in clonal clusters, carrying multiple AMR genes and virulence, with a diverse phenotypic AMR.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"83 3","pages":"168-176"},"PeriodicalIF":0.8,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of external measurements of 3-dimensional (3D) printed biomodels of the canine radius used in an in-hospital setting. 医院环境中使用的犬桡骨三维（3D）打印生物模型的外部测量精度。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2019-07-01

Sebastian Mejia, Nikia Stewart, Angel Miller, Roman Savicky, Christopher Monarski, George E Moore, Dennis Keith

{"title":"Accuracy of external measurements of 3-dimensional (3D) printed biomodels of the canine radius used in an in-hospital setting.","authors":"Sebastian Mejia, Nikia Stewart, Angel Miller, Roman Savicky, Christopher Monarski, George E Moore, Dennis Keith","doi":"","DOIUrl":"","url":null,"abstract":"The objective of this study was to determine if biomodels printed on a fused deposition modeling (FDM) device from computed tomography (CT) data are accurate by comparing external measurements to the native bone, considering that the clinical usefulness of the printed biomodels in an in-hospital setting depends on their verified accuracy and consistency. Using canine cadaveric radii previously stripped of all soft tissues, 7 parameters of the actual bone and the 3-dimensional (3D) printed biomodels were measured and compared to determine how accurately the models represent the cadaveric bone. A total of 28 canine radii were collected, in which the landmarks for measurements were established. Radiographs were then taken to determine the frontal center of rotation of angulation (CORA) and CT scans were carried out. Finally, a 3D virtual reconstruction was done and converted into a stereolithography (STL) format file, from which 2 biomodels were printed per bone. Measurements for biomodels were compared for equivalence to cadaveric measurements. For the 7 measured parameters, the mean difference between biomodel and cadaveric parameters ranged from an increase of +0.66% in cranial-caudal proximal (CrCdP)-CORA to a decrease of -1.32% in distal width of the radius. For all 7 measured parameters, measurements for biomodels were statistically equivalent to their corresponding cadaveric bone (P < 0.001). The 7 measured parameters in the 3D models printed with an FDM device were not significantly different than those in the original bone. In fact, these measurements closely approximated original bone measurements (within 1.5%); therefore, validating their application in future presurgical planning for various orthopedic procedures.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"83 3","pages":"181-186"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587886/pdf/cjvr_03_181.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A missense mutation in MYO7A is associated with bilateral deafness and vestibular dysfunction in the Doberman pinscher breed. MYO7A的一个错义突变与杜宾犬品种的双侧耳聋和前庭功能障碍有关。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2019-04-01

Aubrey A Webb, Alison L Ruhe, Mark W Neff

引用次数: 0

Evaluation of hyaluronic acid, procollagen type III N-terminal peptide, and tissue inhibitor of matrix metalloproteinase-1 as serum markers of canine hepatic fibrosis. 将透明质酸、III型胶原蛋白N端肽和基质金属蛋白酶组织抑制剂-1作为犬肝纤维化的血清标志物进行评估。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2016-10-01

Jonathan A Lidbury, Aline Rodrigues Hoffmann, Joanna K Fry, Jan S Suchodolski, Jörg M Steiner

{"title":"Evaluation of hyaluronic acid, procollagen type III N-terminal peptide, and tissue inhibitor of matrix metalloproteinase-1 as serum markers of canine hepatic fibrosis.","authors":"Jonathan A Lidbury, Aline Rodrigues Hoffmann, Joanna K Fry, Jan S Suchodolski, Jörg M Steiner","doi":"","DOIUrl":"","url":null,"abstract":"The only way to diagnose hepatic fibrosis in dogs is by histological assessment of a liver biopsy specimen. As this technique is invasive and susceptible to sampling variation, serum biomarkers are used to detect hepatic fibrosis in humans. The objective of this study was to assess the utility of hyaluronic acid (HA), procollagen type III N-terminal peptide (PIIINP), and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) as serum markers of canine hepatic fibrosis. Serum samples were collected from 47 dogs with histologically confirmed hepatobiliary disease and 24 healthy dogs in order to measure concentrations of HA, PIIINP, and TIMP-1. Hepatic fibrosis was staged using a 5-point scoring scheme. There was no correlation between serum concentrations of HA or PIIINP and the severity of hepatic fibrosis. There was a negative correlation between serum concentration of TIMP-1 and the severity of hepatic fibrosis (rs = -0.33; P = 0.036). It was not possible to use serum concentrations of HA, PIIINP, or TIMP-1 to discriminate between dogs with absent-to-moderate hepatic fibrosis and those with marked-to-very-marked fibrosis. The results of this study do not support the utility of measuring serum concentrations of HA, PIIINP, or TIMP-1 for diagnosing canine hepatic fibrosis. Further studies are needed to support this finding.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"80 4","pages":"302-308"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical staging in bitches with mammary tumors: Influence of type and histological grade. 乳腺肿瘤母犬的临床分期：类型和组织学分级的影响。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2016-10-01

Lígia F Gundim, Camila P de Araújo, William T Blanca, Ednaldo C Guimarães, Alessandra A Medeiros

{"title":"Clinical staging in bitches with mammary tumors: Influence of type and histological grade.","authors":"Lígia F Gundim, Camila P de Araújo, William T Blanca, Ednaldo C Guimarães, Alessandra A Medeiros","doi":"","DOIUrl":"","url":null,"abstract":"Breast tumors are the most common tumors in dogs and the study of disease prognostic factors is important for establishing the appropriate treatment protocols. The purpose of this study was to clinically stage mammary tumors of bitches and correlate the stages with histological type and grade. The tumors of 63 dogs were clinically staged based on the findings of tumor sizing, lymph node evaluation, and radiographic examination. After surgical excision, the tumors were classified histologically and graded. The relationship between the tumor grade, stage, and histological type was evaluated using a binomial test. Stage I tumors were the most numerous (31.75%), followed by tumors at stages II, III, IV, and V. Animals with histological grade I carcinomas presented stage I, II, or III tumors more frequently and stage IV and V tumors less frequently. The number of animals with simple carcinomas that were at stage I of the disease was greater than that at stage V. Carcinomas in the mixed tumors were less aggressive; however, the small number of animals in stage V of the disease made any statistical association impossible. The complex carcinomas presented with the invasion of the lymph nodes and less cellular differentiation in a larger number of animals than did simple carcinomas. Histological grading proved to be the best parameter for the prognostic evaluation of the breast carcinomas.","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"80 4","pages":"318-322"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140289891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oncolytic reovirus synergizes with chemotherapeutic agents to promote cell death in canine mammary gland tumor. 肿瘤溶解性再病毒与化疗药物协同促进犬乳腺肿瘤细胞死亡。

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire Pub Date : 2016-01-01

Masaya Igase, Chung Chew Hwang, Satoshi Kambayashi, Masato Kubo, Matt Coffey, Takako Shimokawa Miyama, Kenji Baba, Masaru Okuda, Shunsuke Noguchi, Takuya Mizuno

{"title":"Oncolytic reovirus synergizes with chemotherapeutic agents to promote cell death in canine mammary gland tumor.","authors":"Masaya Igase, Chung Chew Hwang, Satoshi Kambayashi, Masato Kubo, Matt Coffey, Takako Shimokawa Miyama, Kenji Baba, Masaru Okuda, Shunsuke Noguchi, Takuya Mizuno","doi":"","DOIUrl":"","url":null,"abstract":"The oncolytic effects of reovirus in various cancers have been proven in many clinical trials in human medicine. Oncolytic virotherapy using reovirus for canine cancers is being developed in our laboratory. The objective of this study was to examine the synergistic anti-cancer effects of a combination of reovirus and low doses of various chemotherapeutic agents on mammary gland tumors (MGTs) in dogs. The first part of this study demonstrated the efficacy of reovirus in canine MGTs in vitro and in vivo. Reovirus alone exerted significant cell death by means of caspase-dependent apoptosis in canine MGT cell lines. A single injection of reovirus impeded growth of canine MGT tumors in xenografted mice, but was insufficient to induce complete tumor regression. The second part of this study highlighted the anti-tumor effects of reovirus in combination with low doses of paclitaxel, carboplatin, gemcitabine, or toceranib. Enhanced synergistic activity was observed in the MGT cell line treated concomitantly with reovirus and in all the chemotherapeutic agents except toceranib. In addition, combining reovirus with paclitaxel or gemcitabine at half dosage of half maximal inhibitory concentration (IC50) enhanced cytotoxicity by activating caspase 3. Our data suggest that the combination of reovirus and low dose chemotherapeutic agents provides an attractive option in canine cancer therapy. ","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"80 1","pages":"21-31"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140195312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0