Canadian journal of veterinary research = Revue canadienne de recherche veterinaire最新文献

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Optimization of conditions related to Chrono-log platelet aggregation in feline whole blood. 猫全血血小板时间日志聚集相关条件的优化。
IF 1.1
WeiChun Huang, Anthony Carr, Kevin Cosford
{"title":"Optimization of conditions related to Chrono-log platelet aggregation in feline whole blood.","authors":"WeiChun Huang, Anthony Carr, Kevin Cosford","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Platelet function testing is a crucial component in the diagnosis and management of hemostatic disorders in feline patients. Despite its importance, standardized methodologies for assessing platelet function in cats remain underexplored. This study aimed to optimize the conditions for Chrono-log platelet impedance aggregometry (IA) in feline whole blood, focusing on the impact of agonist type (collagen or ADP), agonist concentration, and anticoagulant (citrate or hirudin) on platelet aggregation responses. Whole blood from 10 clinically healthy domestic shorthair cats was prospectively evaluated under varying experimental conditions. Our results indicated that hirudin-anticoagulated samples produced significantly higher platelet aggregation responses compared to those anticoagulated with citrate across all agonist concentrations. A partial dose-dependent relationship was observed with collagen but not with ADP. These findings underscore the importance of selecting appropriate assay conditions for accurate platelet function testing in cats. This study provides insight into the methodology of feline whole blood impedance platelet aggregometry using the Chrono-log analyzer.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 4","pages":"136-143"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of risk of dehiscence in dogs and cats after gastrotomy. 狗和猫胃切除术后裂开的风险评估。
IF 1.1
Masha Roman, Daniel Spector
{"title":"Evaluation of risk of dehiscence in dogs and cats after gastrotomy.","authors":"Masha Roman, Daniel Spector","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The objective of this study was to evaluate the rate of dehiscence after surgical gastrotomy in dogs and cats. A secondary objective was to determine factors associated with dehiscence. Electronic medical records were searched for patients (141 dogs and 71 cats) undergoing gastrotomy from 2012 to 2024. Data collected included age, sex, additional procedures done under the same general anesthesia, presence and duration of surgical hypotension, comorbidities, long-term medications, use of a 1- or 2-layer closure, suture pattern of closure, pre-operative lactate and albumin concentrations, American Society of Anesthesiologists (ASA) status, whether or not surgery was done after-hours, a Board-certified surgeon was present, and dehiscence was confirmed. Two of 212 (0.94%) animals had a confirmed gastrotomy dehiscence based on diagnosis of septic peritonitis peri-operatively. These patients had only a gastrotomy, with no other surgical procedures. The dehiscence rate was too low and uncommon to statistically evaluate factors associated with dehiscence after gastrotomy. Confirmed gastrotomy dehiscence rates appeared lower than previously reported in the small intestines. As it was not possible to determine specific factors associated with an increased risk of dehiscence, further studies are required to identify and evaluate such factors.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 4","pages":"144-148"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of HbA1c in identifying dogs at high risk for diabetes despite normal blood glucose levels. HbA1c在识别血糖正常的狗患糖尿病高风险中的作用。
IF 1.1
Jeong-Ho Ha, Yunho Jeong, Jin-Ok Ahn, Jin-Young Chung
{"title":"The role of HbA1c in identifying dogs at high risk for diabetes despite normal blood glucose levels.","authors":"Jeong-Ho Ha, Yunho Jeong, Jin-Ok Ahn, Jin-Young Chung","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The objective of this study was to confirm the clinical utility of hemoglobin A1c (HbA1c) in identifying dogs at a high risk for diabetes. In this cross-sectional study, all the dogs were categorized into a control group and 3 experimental groups (overweight, elderly, and dogs with diseases that can contribute to diabetes). The control group included young and healthy dogs that visited veterinary clinics mainly for health checkups or neutering. The HbA1c concentration of all the dogs was estimated and compared between the control group and the experimental groups. The HbA1c level was significantly higher in the experimental groups than in the control group. In addition, a significant correlation was observed between the HbA1c concentration and all experimental variables. The HbA1c concentration was higher in the overweight group [mean, median: 3.94, 3.9; range (R): 3.5 to 4.3%], the elderly group [mean, median: 3.94, 3.9 (R: 3.5 to 4.3%)], and the disease group [mean, median: 3.99, 4.0 (R: 3.5 to 4.9%)] than in the control group [mean, median: 3.52, 3.6 (R: 2.9 to 3.8%)]. According to the results of this study, HbA1c can be used to evaluate high-risk groups for diabetes in the veterinary field, as in human medicine.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 4","pages":"130-135"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative outcomes following laparotomy-assisted endoscopic removal or gastrotomy for treatment of linear foreign bodies in dogs and cats. 腹腔镜下内镜下切除或胃切开术治疗犬猫线状异物的比较结果。
IF 1.1
Jonah Zitsman, Ryan Ford, Heather Baginski, Garrett Davis
{"title":"Comparative outcomes following laparotomy-assisted endoscopic removal or gastrotomy for treatment of linear foreign bodies in dogs and cats.","authors":"Jonah Zitsman, Ryan Ford, Heather Baginski, Garrett Davis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to compare the outcomes of linear foreign bodies anchored at the pylorus treated <i>via</i> laparotomy-assisted endoscopic removal <i>versus</i> traditional gastrotomy in dogs and cats. The medical records of patients that underwent either procedure from 2020 to 2022 at 1 of 3 affiliated private practice hospitals were reviewed retrospectively. Intra-operative parameters, including surgical time, signalment, pre-operative blood abnormalities, after-hours <i>versus</i> daytime surgeries, and level of surgical training, showed no differences between the 2 groups. The laparotomy-assisted group had a significantly decreased anesthetic time and total hospitalization duration. There was no significant difference in post-operative complication rates between the 2 groups, although incisional infections occurred in 12/121 (10%) of the gastrotomy patients and only 2/24 (8%) of the laparotomy-assisted endoscopy patients. In addition, none of the laparotomy-assisted groups developed post-operative septic peritonitis, whereas septic peritonitis occurred in 2/121 (1.6%) of gastrotomy patients. Laparotomy-assisted endoscopic removal of linear foreign bodies anchored at the pylorus is a viable treatment option that may have the benefits of decreased anesthetic and hospitalization times.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 4","pages":"123-129"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serotype distribution of Actinobacillus pleuropneumoniae isolated from diseased pigs in Argentina (2020-2024). 阿根廷病猪胸膜肺炎放线杆菌血清型分布(2020-2024年)
IF 1.1
Valentina I Cane, Marcelo Gottschalk, Antony T Vincent, Fernando D Cane, Javier E Sarradell, Julia L Cane, Norma B Pereyra
{"title":"Serotype distribution of <i>Actinobacillus pleuropneumoniae</i> isolated from diseased pigs in Argentina (2020-2024).","authors":"Valentina I Cane, Marcelo Gottschalk, Antony T Vincent, Fernando D Cane, Javier E Sarradell, Julia L Cane, Norma B Pereyra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study aimed to monitor the serotype distribution of <i>Actinobacillus pleuropneumoniae</i> (App) in Argentina from 2020 to 2024. A total of 105 App strains, isolated from pigs that died of porcine pleuropneumonia (PP), were serotyped using multiplex PCR. The results showed a predominance of serotype 1 (66.7%), followed by serotypes 4 (12.4%), 5 (7.6%), 7 (6.7%), 8 (4.7%), and 12 (1.9%). This study confirms the continued dominance of serotype 1 in Argentina and highlights the importance of ongoing surveillance to improve disease control strategies.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 4","pages":"149-152"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum. 勘误表。
IF 1.1
{"title":"Erratum.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>[This corrects the article on p. 26 in vol. 89, PMID: 39744463.].</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 4","pages":"129"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of supplementation with Saccharomyces boulardii CNCM I-1079 on the fecal microbiota of healthy young Japanese black calves: A field trial. 添加博氏酵母CNCM I-1079对健康日本幼黑犊牛粪便微生物群的影响:田间试验
IF 0.8
Kazusa Mori, Asato Uchiumi, Kai Yamamoto, Yuki Shimizu, Risa Ueda, Hiroyuki Fukazawa, Hiromichi Ohtsuka
{"title":"Effects of supplementation with <i>Saccharomyces boulardii</i> CNCM I-1079 on the fecal microbiota of healthy young Japanese black calves: A field trial.","authors":"Kazusa Mori, Asato Uchiumi, Kai Yamamoto, Yuki Shimizu, Risa Ueda, Hiroyuki Fukazawa, Hiromichi Ohtsuka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of more than 1 month of supplementation with <i>Saccharomyces boulardii</i> on the gut microbiota of healthy young calves are unclear. The objective of this study was to describe the effects of 7 wk of supplementation with <i>S. boulardii</i> CNCM I-1079 on the fecal bacterial microbiota of healthy young Japanese black calves. Calves in the <i>S. boulardii</i> group (SB group) were fed 2.0 × 10<sup>10</sup> CFUs/day of <i>S. boulardii</i> CNCM I-1079 in milk replacer starting at 2 wk of age. Fecal samples were collected and the V3 and V4 regions of 16S rRNA were sequenced. The SB group exhibited significantly higher fecal alpha diversity at 9 wk of age (7 wk after starting supplementation) than the untreated control group. Beta diversity differed at 6 and 9 wk of age (4 and 7 wk after supplementation). Analysis of the composition of microbiomes revealed that calves in the SB group had higher fecal levels of <i>Bacilli</i>_RF39 than the control group at 9 wk of age. Linear discriminant analysis of effect sizes revealed higher levels of <i>Oscillospiraceae</i> at 3 wk of age (1 wk after) and of <i>Bacilli</i>_RF39 and <i>Atopobiaceae</i> at 9 wk of age (7 wk after) in the SB group than in the control group. Furthermore, a higher abundance of bacteria-producing short-chain fatty acids (SCFAs) was observed at 9 wk of age than at 6 wk in the SB group. These findings indicate that <i>S. boulardii</i> CNCM I-1079 can increase bacterial alpha diversity and might increase the abundance of SCFA-producing bacteria in the gut of healthy young calves.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 3","pages":"91-99"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High expression of prostaglandin EP4 receptor mRNA in feline head and neck squamous cell carcinoma. 前列腺素EP4受体mRNA在猫头颈部鳞状细胞癌中的高表达。
IF 0.8
Margaret L Musser, Raquel Doke, Austin K Viall, Rachel L Phillips, Olufemi Fasina, Chad M Johannes
{"title":"High expression of prostaglandin EP4 receptor mRNA in feline head and neck squamous cell carcinoma.","authors":"Margaret L Musser, Raquel Doke, Austin K Viall, Rachel L Phillips, Olufemi Fasina, Chad M Johannes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Feline head and neck squamous cell carcinoma (HNSCC) has limited treatment options. Previous studies suggest inflammation, mediated by cyclooxygenase-2 and prostaglandin E2 (PGE2), may play a developmental role. PGE2 signals through 1 of 4 receptors: EP1, EP2, EP3, and EP4. Increased expression of EP4 is associated with the development of multiple human and canine cancers but has not been evaluated in feline neoplasms. The objective of this study was to describe the mRNA expression of the EP4 receptor gene <i>(ptger4)</i> in feline HNSCC compared to normal oral mucosal. Archived HNSCC (<i>n</i> = 18) and normal oral mucosa (<i>n</i> = 20) were evaluated for <i>ptger4</i> using RNA <i>in-situ</i> hybridization (RNAscope). HALO was used to quantify RNAscope signals. Data were expressed as copy number, H-index, and percent probe positivity. In HNSCC and normal oral mucosa, mRNA of <i>ptger4</i> was identified. The mRNA expression in HNSCC samples was significantly higher in copy number (<i>P</i> < 0.0001), H-index (<i>P</i> < 0.0001), and percent probe positivity (<i>P</i> < 0.0001) compared to normal oral mucosa. High EP4 receptor expression suggests inflammation may play a role in the development of feline HNSCC. Therapeutically targeting the EP4 receptor with antagonists may add to the current treatment options for this devastating cancer.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 3","pages":"113-119"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of 2 peg sleeve designs on test scores for the laparoscopic peg transfer task. 2钉套设计对腹腔镜钉转移任务测试分数的影响。
IF 0.8
Emily M Austin, Boel A Fransson
{"title":"The effect of 2 peg sleeve designs on test scores for the laparoscopic peg transfer task.","authors":"Emily M Austin, Boel A Fransson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The objective of this study was to determine how the use of 2 different peg sleeve designs would affect the scores of the peg transfer task in laparoscopic skills testing. A total of 22 participants were divided into 3 skill levels: inexperienced (DVM candidates), intermediate (ACVS residents), and expert laparoscopic surgeons (ACVS diplomates). All participants carried out the peg sleeve transfer task using 2 designs of peg sleeves on the same pegboard. The skills test was done in a laparoscopic trainer box using laparoscopic instruments. Participants were randomly assigned to the order in which the peg sleeve designs were tested. The score was based on time taken and errors made and was compared between peg transfers, while controlling for the skill level of the participant. Although no difference was detected between scores obtained using the 2 peg sleeve designs, a warm-up effect, <i>i.e.</i>, a higher score on the second run, was detected across all experience levels in this study population. It was concluded that the 2 sleeve designs appeared to have a minimal impact on the score for the task.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 3","pages":"100-104"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective study of prognostic factors in 29 dogs with surgically treated thymic epithelial tumors. 回顾性研究29只胸腺上皮肿瘤的预后因素。
IF 0.8
Yuko Hashimoto, Dai Nagakubo, Kanako Muta, Masaya Tsuboi, Takayuki Nakagawa, Ryohei Nishimura
{"title":"A retrospective study of prognostic factors in 29 dogs with surgically treated thymic epithelial tumors.","authors":"Yuko Hashimoto, Dai Nagakubo, Kanako Muta, Masaya Tsuboi, Takayuki Nakagawa, Ryohei Nishimura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thymic epithelial tumors (TETs) are a rare type of tumor that occur in the anterior mediastinum. The biological behavior of these tumors and the prognostic factors in dogs remain unclear. Although several studies have suggested that clinical staging (Masaoka classification) is related to prognosis, the prognostic significance of histological subtypes (WHO classification) and paraneoplastic syndromes remains controversial. The objective of this study was to investigate whether paraneoplastic syndromes, Masaoka classification, and WHO classification are associated with the prognosis of canine TET. Hypercalcemia and anemia were observed as paraneoplastic syndromes in the 29 dogs included in this study. The presence of hypercalcemia did not result in a statistical difference in median survival time. Anemia could not be statistically analyzed due to the small number of cases. Our results suggest that the WHO classification, like the Masaoka classification, may also be useful for predicting the prognosis of canine TET.</p>","PeriodicalId":93919,"journal":{"name":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire","volume":"89 3","pages":"105-112"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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