BMJ (Clinical research ed.)最新文献

{"title":"Medical devices: Government vows to tackle ethnic inequities.","authors":"Elisabeth Mahase","doi":"10.1136/bmj.q647","DOIUrl":"10.1136/bmj.q647","url":null,"abstract":"","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"384 ","pages":"q647"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"25 year trends in cancer incidence and mortality among adults aged 35-69 years in the UK, 1993-2018: retrospective secondary analysis.","authors":"Jon Shelton, Ewa Zotow, Lesley Smith, Shane A Johnson, Catherine S Thomson, Amar Ahmad, Lars Murdock, Diana Nagarwalla, David Forman","doi":"10.1136/bmj-2023-076962","DOIUrl":"10.1136/bmj-2023-076962","url":null,"abstract":"<p><strong>Objective: </strong>To examine and interpret trends in UK cancer incidence and mortality for all cancers combined and for the most common cancer sites in adults aged 35-69 years.</p><p><strong>Design: </strong>Retrospective secondary data analysis.</p><p><strong>Data sources: </strong>Cancer registration data, cancer mortality and national population data from the Office for National Statistics, Public Health Wales, Public Health Scotland, Northern Ireland Cancer Registry, NHS England, and the General Register Office for Northern Ireland.</p><p><strong>Setting: </strong>23 cancer sites were included in the analysis in the UK.</p><p><strong>Participants: </strong>Men and women aged 35-69 years diagnosed with or who died from cancer between 1993 to 2018.</p><p><strong>Main outcome measures: </strong>Change in cancer incidence and mortality age standardised rates over time.</p><p><strong>Results: </strong>The number of cancer cases in this age range rose by 57% for men (from 55 014 cases registered in 1993 to 86 297 in 2018) and by 48% for women (60 187 to 88 970) with age standardised rates showing average annual increases of 0.8% in both sexes. The increase in incidence was predominantly driven by increases in prostate (male) and breast (female) cancers. Without these two sites, all cancer trends in age standardised incidence rates were relatively stable. Trends for a small number of less common cancers showed concerning increases in incidence rates, for example, in melanoma skin, liver, oral, and kidney cancers. The number of cancer deaths decreased over the 25 year period, by 20% in men (from 32 878 to 26 322) and 17% in women (28 516 to 23 719); age standardised mortality rates reduced for all cancers combined by 37% in men (-2.0% per year) and 33% in women (-1.6% per year). The largest decreases in mortality were noted for stomach, mesothelioma, and bladder cancers in men and stomach and cervical cancers and non-Hodgkin lymphoma in women. Most incidence and mortality changes were statistically significant even when the size of change was relatively small.</p><p><strong>Conclusions: </strong>Cancer mortality had a substantial reduction during the past 25 years in both men and women aged 35-69 years. This decline is likely a reflection of the successes in cancer prevention (eg, smoking prevention policies and cessation programmes), earlier detection (eg, screening programmes) and improved diagnostic tests, and more effective treatment. By contrast, increased prevalence of non-smoking risk factors are the likely cause of the observed increased incidence for a small number of specific cancers. This analysis also provides a benchmark for the following decade, which will include the impact of covid-19 on cancer incidence and outcomes.</p>","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"384 ","pages":"e076962"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10935512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wegovy: FDA approves weight loss drug to cut cardiovascular risk.","authors":"Janice Hopkins Tanne","doi":"10.1136/bmj.q642","DOIUrl":"10.1136/bmj.q642","url":null,"abstract":"","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"384 ","pages":"q642"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coroner warns of \"multiple failures\" that contributed to child's death from asthma.","authors":"Clare Dyer","doi":"10.1136/bmj.q641","DOIUrl":"10.1136/bmj.q641","url":null,"abstract":"","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"384 ","pages":"q641"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NHS staff to receive paid leave following pregnancy loss.","authors":"Abi Rimmer","doi":"10.1136/bmj.q638","DOIUrl":"10.1136/bmj.q638","url":null,"abstract":"","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"384 ","pages":"q638"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140133496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homelessness is a public health emergency, report warns.","authors":"Jacqui Wise","doi":"10.1136/bmj.q632","DOIUrl":"10.1136/bmj.q632","url":null,"abstract":"","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"384 ","pages":"q632"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early psychosis for the non-specialist doctor.","authors":"Musa Basseer Sami, David Shiers, Saqib Latif, Sagnik Bhattacharyya","doi":"10.1136/bmj.j4578","DOIUrl":"10.1136/bmj.j4578","url":null,"abstract":"","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"357 ","pages":"j4578"},"PeriodicalIF":0.0,"publicationDate":"2017-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35236407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Former editor who fabricated data is suspended for four months.","authors":"Clare Dyer","doi":"10.1136/bmj.j4537","DOIUrl":"https://doi.org/10.1136/bmj.j4537","url":null,"abstract":"A former editor of the British Journal of Diabetes who was found last April to have fabricated research data and forged the signatures of coauthors has been suspended from the UK medical register for four months.\u0000\u0000Paul Grant had been appointed editor in chief of Clinical Medicine , the journal of the Royal College of Physicians, when allegations surfaced of irregularities in five research papers he submitted. He never took up the post.\u0000\u0000Two of the papers were published and later retracted. The most serious allegations concerned a study of anxiety and depression in 350 patients with type 1 diabetes …","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"358 ","pages":"j4537"},"PeriodicalIF":105.7,"publicationDate":"2017-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.j4537","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35401022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiologist is cleared of sexual assault charges.","authors":"Clare Dyer","doi":"10.1136/bmj.j4533","DOIUrl":"https://doi.org/10.1136/bmj.j4533","url":null,"abstract":"A consultant cardiologist has been cleared of sexually assaulting three women during medical examinations at Lewisham Hospital in southeast London.\u0000\u0000Sumit Basu, 59, was acquitted at Woolwich Crown Court in London of seven charges of sexual assault and three charges of assault by penetration against the three women between 2006 and 2014.\u0000\u0000Allegations were first made to …","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"358 ","pages":"j4533"},"PeriodicalIF":105.7,"publicationDate":"2017-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.j4533","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35456472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are radical changes to health and social care paving the way for fewer services and new user charges?","authors":"","doi":"10.1136/bmj.j4531","DOIUrl":"https://doi.org/10.1136/bmj.j4531","url":null,"abstract":"Seismic changes in the organisation, delivery, and funding of health and social care services have been underway since the secretary of state’s duty to provide key services throughout England was abolished by the Health and Social Care Act 2012. One of the acts’ major changes was to transfer public health responsibilities to local authorities—described as “one of the most significant extensions of local government powers and duties in a generation.” The Cities and Local Government Devolution Act 2016 allows further health functions to be devolved to local authorities. At the same time, NHS England is implementing sustainability and transformation plans (STPs) covering 44 geographical “footprints” in England. These have been reported to be required to cut 26bn (€29bn; $35bn) from health and social care costs over five years. STPs are intended to pool the budgets of health bodies and local authorities for joint commissioning of health and social care services, creating new organisational forms and care models, such as newly proposed accountable care organisations. The devolution deals and STPs are being presented to the public and health professionals as a way of integrating health and local authority social care. But missing from the picture is their fundamentally different funding bases: social care is a local authority responsibility and subject to means testing and user charges, whereas NHS services are free at the point of delivery. These changes are taking place while the NHS undergoes the largest sustained reduction in spending as a percentage of gross domestic product (GDP) since 1951, NHS providers have recorded their highest ever deficit, and there has been a 37% real terms reduction in local authority funding from central government grants from 2010 to 2016 (excluding public health and the Better Care Fund), alongside the ongoing radical and regressive reform of local government finance. How will these changes and reductions in funding affect access to care, equity, and already widening inequalities? Experience from the last major transfer of responsibilities from the NHS to local authorities suggests they are likely to lead to reduced services and entitlements, more private provision of publicly funded services and, potentially, the introduction of charges for health services. Effects on services and entitlements","PeriodicalId":93911,"journal":{"name":"BMJ (Clinical research ed.)","volume":"358 ","pages":"j4531"},"PeriodicalIF":105.7,"publicationDate":"2017-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.j4531","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35401019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}