Biological psychiatry. Cognitive neuroscience and neuroimaging最新文献

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Cognitive Phenotype Shifts in Risk Taking: Interplay of Nonsuicidal Self-Injury Behaviors and Intensified Depression. 冒险行为的认知表型转变：非自杀性自伤行为与抑郁加剧的相互作用。

Biological psychiatry. Cognitive neuroscience and neuroimaging Pub Date : 2024-06-11 DOI: 10.1016/j.bpsc.2024.05.011

Yi-Long Lu, Yuqi Ge, Mingzhu Li, Shutian Liang, Xiaoxi Zhang, Yupeng Sui, Lei Yang, Xueni Li, Yuyanan Zhang, Weihua Yue, Hang Zhang, Hao Yan

{"title":"Cognitive Phenotype Shifts in Risk Taking: Interplay of Nonsuicidal Self-Injury Behaviors and Intensified Depression.","authors":"Yi-Long Lu, Yuqi Ge, Mingzhu Li, Shutian Liang, Xiaoxi Zhang, Yupeng Sui, Lei Yang, Xueni Li, Yuyanan Zhang, Weihua Yue, Hang Zhang, Hao Yan","doi":"10.1016/j.bpsc.2024.05.011","DOIUrl":"10.1016/j.bpsc.2024.05.011","url":null,"abstract":"Background: Nonsuicidal self-injury (NSSI) behavior is significantly prevalent in both adolescents and psychiatric populations, particularly in individuals with major depressive disorder. NSSI can be considered a result of risky decision making in response to negative emotions, where individuals choose self-harm over other less harmful alternatives, suggesting a potential decision-making deficit in those engaging in NSSI. This study delves into the complex relationship between NSSI and depression severity in decision making and its cognitive underpinnings.Methods: We assessed decision behaviors in 57 patients with major depressive disorder and NSSI, 42 patients with major depressive disorder without NSSI, and 142 healthy control participants using the Balloon Analog Risk Task, which involves risk taking, learning, and exploration in uncertain scenarios. Using computational modeling, we dissected the nuanced cognitive dimensions influencing decision behaviors. A novel statistical method was developed to elucidate interaction effects between NSSI and depression severity.Results: Contrary to common perceptions, we found that individuals with NSSI behaviors were typically more risk averse. There was also a complex interaction between NSSI and depression severity in shaping risk-taking behaviors. As depressive symptoms intensified, the individuals with NSSI began to perceive less risk and behave more randomly.Conclusions: This research provides new insights into the cognitive aspects of NSSI and depression, highlighting the importance of considering the influence of comorbid mental disorders when investigating the cognitive underpinnings of such behaviors, especially in the context of prevalent cross-diagnostic phenomena such as NSSI behaviors.","PeriodicalId":93900,"journal":{"name":"Biological psychiatry. Cognitive neuroscience and neuroimaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141319306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating Exploitative Traps: Unveiling the Uncontrollable Reward Seeking of Individuals With Internet Gaming Disorder. 探索剥削陷阱：揭开网络游戏障碍者无法控制的奖励追求。

Biological psychiatry. Cognitive neuroscience and neuroimaging Pub Date : 2024-06-03 DOI: 10.1016/j.bpsc.2024.05.005

Lin Zuo, Kedan Ai, Weili Liu, Bensheng Qiu, Rui Tang, Jiaxin Fu, Ping Yang, Zhuo Kong, Hongwen Song, Xiaoyu Zhu, Xiaochu Zhang

{"title":"Navigating Exploitative Traps: Unveiling the Uncontrollable Reward Seeking of Individuals With Internet Gaming Disorder.","authors":"Lin Zuo, Kedan Ai, Weili Liu, Bensheng Qiu, Rui Tang, Jiaxin Fu, Ping Yang, Zhuo Kong, Hongwen Song, Xiaoyu Zhu, Xiaochu Zhang","doi":"10.1016/j.bpsc.2024.05.005","DOIUrl":"10.1016/j.bpsc.2024.05.005","url":null,"abstract":"Background: Internet gaming disorder (IGD) involves an imbalance in the brain's dual system, characterized by heightened reward seeking and diminished cognitive control, which lead to decision-making challenges. The exploration-exploitation strategy is key to decision making, but how IGD affects this process is unclear.Methods: To investigate the impact of IGD on decision making, a modified version of the 2-armed bandit task was employed. Participants included 41 individuals with IGD and 44 healthy control individuals. The study assessed the strategies used by participants in the task, particularly focusing on the exploitation-exploration strategy. Additionally, functional magnetic resonance imaging was used to examine brain activation patterns during decision-making and estimation phases.Results: The study found that individuals with IGD demonstrated greater reliance on exploitative strategies in decision making due to their elevated value-seeking tendencies and decreased cognitive control. Individuals with IGD also displayed heightened activation in the presupplementary motor area and the ventral striatum compared with the healthy control group in both decision-making and estimation phases. Meanwhile, the prefrontal cortex showed more inhibition in individuals with IGD than in the healthy control group during exploitative strategies. This inhibition decreased as cognitive control diminished.Conclusions: The imbalance in the development of the dual system in individuals with IGD may lead to an overreliance on exploitative strategies. This imbalance, marked by increased reward seeking and reduced cognitive control, contributes to difficulties in decision making and value-related behavioral processes in individuals with IGD.","PeriodicalId":93900,"journal":{"name":"Biological psychiatry. Cognitive neuroscience and neuroimaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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