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Best practice & research. Clinical endocrinology & metabolism最新文献

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Predominantly cystic craniopharyngiomas: Current management approaches, outcomes and limitations. 主要是囊性颅咽管瘤：目前的治疗方法，结果和局限性。
Best practice & research. Clinical endocrinology & metabolism Pub Date : 2025-02-05 DOI: 10.1016/j.beem.2025.101981
Francesco Calvanese, Gianpaolo Jannelli, Camille Sergeant, Romain Manet, Loic Feuvret, François Ducray, Gèrarld Raverot, Emmanuel Jouanneau
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引用次数: 0
Autoimmune Addison's disease. 自身免疫性艾迪生病。
Best practice & research. Clinical endocrinology & metabolism Pub Date : 2020-01-01 DOI: 10.1056/nejm196312122692422
Serena Saverino, A. Falorni
{"title":"Autoimmune Addison's disease.","authors":"Serena Saverino, A. Falorni","doi":"10.1056/nejm196312122692422","DOIUrl":"https://doi.org/10.1056/nejm196312122692422","url":null,"abstract":"Primary adrenal insufficiency (PAI) occurs in 1/5000-1/7000 individuals in the general population. Autoimmune Addison's disease (AAD) is the major cause of PAI and is a major component of autoimmune polyendocrine syndrome type 1 (APS1) and type 2 (APS2). Presence of 21-hydroxylase autoantibodies (21OHAb) identifies subjects with ongoing clinical or pre-clinical adrenal autoimmunity. AAD requires life-long substitutive therapy with two-three daily doses of hydrocortisone (HC) (15-25 mg/day) or one daily dose of dual-release HC and with fludrocortisone (0.5-2.0 mg/day). The lowest possible HC dose must be identified according to clinical and biochemical parameters to minimize long-term complications that include osteoporosis and cardiovascular and metabolic alterations. Women with AAD have lower fertility and parity as compared to age-matched healthy controls. Patients must be educated to double-triple HC dose in the case of fever or infections and to switch to parenteral HC in the case of vomiting, diarrhoea or acute hypotension.","PeriodicalId":93894,"journal":{"name":"Best practice & research. Clinical endocrinology & metabolism","volume":"1 1","pages":"101379"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1056/nejm196312122692422","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42725642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Puberty. 青春期。
Best practice & research. Clinical endocrinology & metabolism Pub Date : 2019-02-15 DOI: 10.1002/9781119386230.ch5
M. Zacharin
{"title":"Puberty.","authors":"M. Zacharin","doi":"10.1002/9781119386230.ch5","DOIUrl":"https://doi.org/10.1002/9781119386230.ch5","url":null,"abstract":"","PeriodicalId":93894,"journal":{"name":"Best practice & research. Clinical endocrinology & metabolism","volume":"1 1","pages":"101301"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9781119386230.ch5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43739674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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