Archives of gerontology and geriatrics最新文献

{"title":"Effect of temporal variation in social activity participation on physical frailty among community-dwelling middle-aged and older adults: A longitudinal study with a three-wave survey.","authors":"Yuya Goto, Koji Yamatsu","doi":"10.1016/j.archger.2025.105979","DOIUrl":"10.1016/j.archger.2025.105979","url":null,"abstract":"<p><p>An aging population necessitates strategies for extending healthy lifespan, with physical frailty as a key obstacle. Social activity participation is a potential intervention. However, previous studies examining the association between social activity participation and physical frailty have predominantly employed cross-sectional designs with single-wave surveys or longitudinal designs with two-wave surveys, and studies using multi-wave longitudinal designs are limited. Few studies have systematically evaluated the classification of physical frailty in subsequent follow-up assessments while considering temporal variations in social activity participation. Therefore, we studied the effect of temporal variations in social activity on subsequent physical frailty classifications using a three-wave survey. We found that sustained non-participation in sports-based activities significantly increased the risk of Pre-Frailty or Frailty at follow-up compared to sustained participation. Similarly, transitioning from participation to non-participation in culture-based activities increased this risk. These results suggest that maintaining participation in sports activities and avoiding cessation of cultural activities are crucial for preventing frailty. Individuals who consistently avoided sports or stopped cultural activities were more likely to be classified as pre-frail or frail in subsequent assessments.</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"138 ","pages":"105979"},"PeriodicalIF":3.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Employment outcomes for older adults aged 50-74 by major local industry typology and the health of a place: findings from the ONS Longitudinal Study 2001-2011.","authors":"Nicola Shelton, Paul Norman, Jenny Head, Emily T Murray","doi":"10.1016/j.archger.2025.105973","DOIUrl":"10.1016/j.archger.2025.105973","url":null,"abstract":"<p><strong>Objectives: </strong>Poor health at the individual and area level has been shown to be associated with earlier labour market exit. This paper builds on work demonstrating that health in a place is associated with higher chances of work exit for older workers even once their own health is taken into account. This paper looks at an additional risk factor for work exit: industrial mix.</p><p><strong>Study design: </strong>Data was drawn from the full 2011 Census and an approximately 1.1 % representative sample from England and Wales, the Office for National Statistics Longitudinal Study from 2001 to 2011.</p><p><strong>Methods: </strong>We analysed people aged 40-64 in paid work in 2001 and measured their employment outcomes in 2011, at ages 50-74. Four industrial landscape clusters were derived by K-means cluster analysis using industry mix for 348 local authorities from 2011 Census. 'Health of a place' was measured using 2001 Census data for the usually resident population aged 50-74 years, the proportion who reported 'fair', 'bad' or 'very bad' self-rated health (as opposed to 'good' or 'very good') was calculated and split into tertiles.</p><p><strong>Results: </strong>Work exit showed industrial landscape and area health inequalities. Older workers in healthy service sector areas in London had the lowest work exit chances with a gradient to those in unhealthy rural areas having the highest chance of work exit.</p><p><strong>Conclusions: </strong>More research is required to investigate why, in areas where the same types of industry dominate, the health of the local population was associated with differing odds of work exit.</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"138 ","pages":"105973"},"PeriodicalIF":3.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex and gender differences in caregiver burden among family caregivers of persons with dementia: A systematic review and meta-analysis.","authors":"Thitinan Duangjina, Thanakrit Jeamjitvibool, Chang Park, Rebecca Raszewski, Valerie Gruss, Cynthia Fritschi","doi":"10.1016/j.archger.2025.105977","DOIUrl":"10.1016/j.archger.2025.105977","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review and meta-analysis examined sex and gender differences in caregiver burden among family caregivers of persons with dementia and explored variations by region and country income level.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a comprehensive literature search was conducted in four databases (CINAHL, PubMed, EMBASE, and PsycINFO), including studies up to December 2024. Forty-seven studies representing 24 countries were included in the systematic review, with 39 studies (41 effect sizes) included in the meta-analysis. A random-effects model was used to calculate pooled effect sizes (Cohen's d), and subgroup analyses were performed based on region and national income level.</p><p><strong>Results: </strong>Across the 47 studies, 14,919 family caregivers participated, of whom 70 % were women. Most family caregivers were either spouses (44 %) or adult children (43 %). Care recipients were predominantly diagnosed with Alzheimer's disease. Female caregivers reported significantly greater burden than males (Cohen's d= 0.21, 95 % CI: 0.13-0.29, p< 0.001). Subgroup analyses showed higher burden in Asian countries (d= 0.27) compared to Western countries (d= 0.19), though the difference was not statistically significant. High-income countries showed greater disparities (d= 0.21) than middle-income countries (d= 0.16), with no significant difference. High heterogeneity was observed among Western and high-income countries.</p><p><strong>Conclusion: </strong>Female family caregivers experience a higher burden than male caregivers across regions and economic settings. Although regional and income-level subgroup differences were not statistically significant, findings underscore the role of cultural and structural contexts in shaping caregiver burden. Gender-sensitive, context specific interventions are essential to address these disparities.</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"138 ","pages":"105977"},"PeriodicalIF":3.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence for health promotion interventions to improve cognitive and physical functioning outcomes in older adults with MCI: A state-of-the-art review.","authors":"Tasmin Alanna Rookes, Rachael Frost, Louise Marston, Megan Armstrong, Yolanda Barrado-Martin, Kate Walters","doi":"10.1016/j.archger.2025.106049","DOIUrl":"https://doi.org/10.1016/j.archger.2025.106049","url":null,"abstract":"<p><strong>Background: </strong>Health promotion activities for people with mild cognitive impairment (MCI) may improve their overall health and prevent progression to dementia. We need to understand the best approaches to behaviour change in this population.</p><p><strong>Aim: </strong>To summarise the types of health promotion interventions and current clinical effectiveness evidence for physical and cognitive functioning outcomes in people with MCI.</p><p><strong>Design: </strong>State-of-the art review METHOD: Medline was searched in April 2025, for systematic reviews synthesising randomised controlled trials testing effectiveness of health promotion interventions in older adults with MCI, published since 2015. Abstracts, titles, and full texts were single screened and, for eligible reviews, the characteristics, intervention type, primary outcome, and evidence for people with MCI, were extracted. Key messages were narratively synthesised across reviews, grouping by type of intervention and outcome measure.</p><p><strong>Results: </strong>From 1776 titles and abstracts, 57 systematic reviews were eligible. Regular moderate intensity multicomponent physical exercise and memory-focussed cognitive training interventions had the strongest evidence base for improving cognitive functioning. However, combining physical exercise and cognitive training was more beneficial for cognitive domains and physical functioning, in comparison to doing them individually. The evidence for nutrition interventions was mixed. One review of psychological interventions showed improvements for wellbeing.</p><p><strong>Conclusion: </strong>There is evidence that health promotion interventions can support people with MCI and dementia to improve or maintain their cognitive function, through multicomponent physical activity combined with cognitive training. More evidence is needed for nutritional recommendations, psychological interventions, and social inclusion interventions.</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"140 ","pages":"106049"},"PeriodicalIF":3.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of music therapy on agitation in elderly patients with dementia: A systematic review and meta-analysis.","authors":"Jing Hu, Ling Xu","doi":"10.1016/j.archger.2025.106048","DOIUrl":"https://doi.org/10.1016/j.archger.2025.106048","url":null,"abstract":"<p><p>Agitation impacts 50 - 80 % of elderly dementia patients, imposing burdens on caregivers and healthcare systems. Pharmacological treatments are limited, whereas non-pharmacological music therapy (MT) holds promise. This study sought to evaluate MT's efficacy in alleviating agitation. A thorough search across multiple databases was carried out, incorporating 14 studies (10 RCTs, 4 pre-post trials; n = 847). Meta-analysis demonstrated that MT significantly reduced agitation with a moderate effect size (d = 0.42). Subgroup analyses yielded consistent findings. Heterogeneity was low, and publication bias was negligible. MT effectively mitigated agitation in dementia patients despite heterogeneity in aspects like music duration and genre, underscoring its generalizability, particularly in resource-constrained areas and households lacking professional nursing support. It offers evidence for integrating MT into patient care. The review was registered on PROSPERO (CRD420251033860).</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"140 ","pages":"106048"},"PeriodicalIF":3.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interaction between activities of daily living and psychological resilience on all-cause mortality and cognitive impairment among Chinese older adults: A cohort study based on CLHLS.","authors":"Yingtian Wang, Haining Qi, Xinru Hu, Qian Yu, Manshu Yu, Fan Yang, Xirui Qiu, Fangyi Chen, Ye Ding, Meng Jiang, Xiaoxiao Wang, Li Liu, Wei Wang","doi":"10.1016/j.archger.2025.106047","DOIUrl":"https://doi.org/10.1016/j.archger.2025.106047","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the joint effects and interactions of psychological resilience (PR) and activities of daily living (ADL) on cognitive impairment and all-cause mortality.</p><p><strong>Methods: </strong>Chinese older adults were recruited from the Chinese Longitudinal Healthy Longevity Survey. Cox proportional hazards regression and log-binomial regression were employed to estimate the associations between exposures and all-cause mortality and cognitive impairment (defined as MMSE score <18 or self-reported dementia). Interactions were test on the basis of multivariable regressions.</p><p><strong>Results: </strong>Compared to participants with normal ADL and high PR (Group 1), participants with limited ADL and high PR (Group 3, HR = 2.105; 95 % CI: 1.656, 2.676) and those with limited ADL and low PR (Group 4, HR = 3.076; 95 % CI: 2.436, 3.884) showed significantly increased risks of all-cause mortality. Moreover, the synergistic interactions between ADL and PR for all-cause mortality were evidenced by relative excess risk due to interaction (RERI = 0.824; 95 % CI: 0.363, 1.286), attributable proportion due to interaction (AP = 0.268; 95 % CI: 0.121, 0.415) and synergy index (SI = 1.659; 95 % CI: 1.134, 2.426). Regarding cognitive impairment, compared to Group 1, Group 3 (RR = 1.662; 95 % CI: 1.073, 2.576) and Group 4 (RR = 2.138; 95 % CI: 1.399, 3.8) exhibited increased risks. Additionally, subgroup analysis showed additive interaction for cognitive impairment was significant only in males.</p><p><strong>Conclusions: </strong>Limited ADL and low PR jointly increase the risks of cognitive impairment and all-cause mortality in Chinese older adults, with a synergistic additive interaction observed for all-cause mortality.</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"140 ","pages":"106047"},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and enablers to primary care in Australian residential aged care homes: A scoping review.","authors":"Jolyn Johal, Heather Block, Alison Dymmott, Elsa Dent, Helen Exley, Stacey George","doi":"10.1016/j.archger.2025.106032","DOIUrl":"https://doi.org/10.1016/j.archger.2025.106032","url":null,"abstract":"<p><strong>Objectives: </strong>To identify barriers and enablers to primary care in Australian residential aged care homes (RACHs).</p><p><strong>Study design: </strong>Scoping review of articles published from 2019 to June 2024 in which barriers and enablers to primary care in Australian RACHs have been quantitatively measured, qualitatively collected or reported following implementation.</p><p><strong>Data sources: </strong>Medline, CINAHL, AgeLine, Cochrane, Scopus, JBI, and Google Scholar.</p><p><strong>Data synthesis: </strong>Of 1705 records screened, 28 studies were included, which were predominantly qualitative or mixed methods. They included general practitioner, nurse practitioner, pharmacy, allied health, oral health and dental services. Ninety barriers and 72 enablers were identified, and inductively classified into seven categories: System Level: 1. Funding and Resources; Organisational Level: 2. Employment and Service Models, 3. Management and Culture and, 4. Collaboration, Coordination and Communication; and Individual Level: 5. Workload, Job Satisfaction and Security, 6. Attributes, Skills and Preparedness for Role and, 7. Recipient Needs, Attitudes and Preferences. Barriers and enablers related to 'Funding and Resources' and 'Employment and Service Models' appeared key, interacting with multiple categories. On-site models were reported to foster greater collaboration and care.</p><p><strong>Conclusions: </strong>This review revealed the systems-, organisational- and individual-level factors that influence primary care in Australian RACHs. These can be considered when designing future initiatives to increase primary care access in RACHs. With the Australian Government recently introducing funding to employ on-site pharmacists, this is an opportunity for systematic evaluation of on-site models to inform future policies, which can be considered for extension to other professions.</p><p><strong>Registration: </strong>Open Science Framework, https://osf.io/nyqrm/.</p>","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"140 ","pages":"106032"},"PeriodicalIF":3.8,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory age and its impact on age-related health in older Chinese adults","authors":"Rui Zhen Wang, W. Zhang, Chao Qiang Jiang, Feng Zhu, Y. Jin, Lin Xu","doi":"10.1016/j.archger.2024.105476","DOIUrl":"https://doi.org/10.1016/j.archger.2024.105476","url":null,"abstract":"","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"47 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141029156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Transcriptomic and Proteomic Data for a Comprehensive Molecular Perspective on the Association between Sarcopenia and Osteoporosis","authors":"Jincheng Chen, Jie Xu, Lingyun Gou, Yong Zhu, Weihua Zhong, Hai Guo, Yujuan Du","doi":"10.1016/j.archger.2024.105486","DOIUrl":"https://doi.org/10.1016/j.archger.2024.105486","url":null,"abstract":"","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"54 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141042781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Science-Based Review of the World's Best-Selling Book on Aging.","authors":"Charles Brenner","doi":"10.1016/j.archger.2022.104825","DOIUrl":"10.1016/j.archger.2022.104825","url":null,"abstract":"","PeriodicalId":93880,"journal":{"name":"Archives of gerontology and geriatrics","volume":"104 ","pages":"104825"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}