Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft最新文献

{"title":"Peer-Assisted Uniform Learning in Musculoskeletal Anatomy: Enhancing Performance Across Cognitive Domains in Objective Structured Practical Examination.","authors":"Sadia Qazi, Shahid Akhund, Muhammad Atif Mazhar, Aftab Ahmed Shaikh, Eshal Atif, Samir Odeh, Mohammed Alged Elsheikh Musa, Hassan Shaibah, Paul Ganguly, Ahmed Yaqinuddin","doi":"10.1016/j.aanat.2025.152744","DOIUrl":"https://doi.org/10.1016/j.aanat.2025.152744","url":null,"abstract":"<p><strong>Background: </strong>Peer-assisted learning enhances conceptual understanding in anatomy education; however, its impact on structured cognitive outcomes remains unclear. We evaluated the effect of the Peer-Assisted Uniform Learning (PAUL) program on musculoskeletal (MSK) anatomy objective structured practical examination (OSPE) performance.</p><p><strong>Methods: </strong>We used a cross-sectional, controlled, observational design to analyse the OSPE scores of 304 students. Seventy-nine students who attended at least two PAUL sessions formed the exposure group, while 225 served as the control group. The PAUL participants alternated between tutor and tutee roles during the sessions. The OSPE items were divided into Cluster 1 (identification/recall) and Cluster 2 (application/analysis). A validated survey was used to assess the participants perceived learning outcomes and satisfaction.</p><p><strong>Results: </strong>PAUL participants outperformed non-participants in Cluster 1 (78.4 vs. 73.7, p = 0.01) and Cluster 2 (87.2 vs. 82.8, p = 0.02). The relative gain was greater for application-based items (interaction effect: F = 8.37, p = 0.004), supporting the program's effect on higher-order reasoning. Survey responses (91% response rate) showed high satisfaction (mean 4.3 ± 0.6) and perceived learning gains (mean 4.1 ± 0.7); 85% of students reported improved understanding of the subject.</p><p><strong>Conclusion: </strong>The PAUL program, grounded in social constructivist principles and supported by faculty oversight, improved performance in both recall and application of MSK anatomy OSPE items, with the strongest impact on application-based learning.</p>","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":" ","pages":"152744"},"PeriodicalIF":1.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Canals and grooves for the supraclavicular nerves revisited: Anatomical and radiological study outlining their topography for clinical practice.","authors":"Anhelina Khadanovich, Judita Kamlerova, Sarlota Havlikova, Michal Benes, Petr Fulin, David Kachlik, Vojtech Kunc","doi":"10.1016/j.aanat.2025.152742","DOIUrl":"https://doi.org/10.1016/j.aanat.2025.152742","url":null,"abstract":"<p><strong>Objectives: </strong>Supraclavicular nerves cross the clavicle to provide sensory innervation to the skin over the clavicle, ventromedial shoulder region and upper part of the thorax. Although rare, they may variably perforate the clavicle throughout their course. Since the current literature lacks a comprehensive analysis of the resultant canals and grooves for the supraclavicular nerves, this study aimed to provide detailed morphometric and topographical data for clinical practice.</p><p><strong>Materials and methods: </strong>In total, 524 dry clavicles and 200 CT images were assessed for the presence of canals or grooves for the supraclavicular nerves. Morphometric parameters were digitally measured, and correlated between dry bones and supraclavicular nerves' course in ten formaldehyde-preserved neck regions. Radiological observations were assessed for their suitability in preoperative planning.</p><p><strong>Results: </strong>Twenty-two out of 524 dry clavicles (4.2%) featured a canal for the supraclavicular nerve, and a groove was present in 6 cases (1.1%). The average distances from the sternal and acromial ends to the closest margin of the canal or groove corresponded to the course of the intermediate supraclavicular nerve. A canal was detected in eight out of 200 CTs (4%) while a groove was not identified at all.</p><p><strong>Conclusion: </strong>Although both variations are rare, canals for the supraclavicular nerves appear more frequently. Both canals and grooves for the supraclavicular nerves are indentations of the intermediate supraclavicular nerve. These data can be implicated in the management of clavicular fractures and surgical decompression of the neural entrapment within the canal or the groove.</p>","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":" ","pages":"152742"},"PeriodicalIF":1.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical mapping of porcine dentin and branches with Brillouin confocal VIPA-based microscopy.","authors":"Richard Younes, Frédéric Cuisinier, Benoit Rufflé, Rémy Vialla, Shahid Ali Shah, Pierre-Yves Collart-Dutilleul, Alban Desoutter","doi":"10.1016/j.aanat.2025.152743","DOIUrl":"10.1016/j.aanat.2025.152743","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the mechanical properties of porcine dentin using Brillouin confocal microscopy, focusing on its tubules and canaliculi. By mapping the Brillouin shift, we aimed to gain deeper insight into dentin biomechanics and assess how porcine dentin compares to human dentin as a model for dental research.</p><p><strong>Design: </strong>Porcine molars were prepared by dehydration, precision cutting and polishing. A Brillouin microscope with a dual-VIPA configuration was used for spectral acquisition at 0.3 µm steps. Brillouin frequency shift, full width at half maximum (FWHM) and intensity were analyzed.</p><p><strong>Results: </strong>Brillouin microscopy identified three distinct zones in porcine dentin: tubules, intertubular regions and branching areas, similar to human dentin. The Brillouin shifts ranged from 17 to 21.5 GHz, with an average around 19 GHz, lower than the 20-25 GHz typically found in human dentin. Mapping revealed branching tubules resembling tree trunks, with intricate branch-like structures in the intertubular regions. Peritubular areas exhibited higher frequency shifts, reaching around 21 GHz, distinguishing them from the more uniform intertubular zones. The dense branch networks surrounded by harder material provided insights into dentin's microstructure. However, challenges in refractive index and density measurements hindered direct conversion of frequency shifts to precise elastic longitudinal modulus values.</p><p><strong>Conclusion: </strong>This study demonstrated that Brillouin VIPA-based microscopy can effectively map the mechanical properties of porcine dentin. The results show its potential for non-contact, high-resolution mechanical histology in biological tissues, offering promise for studying healthy and diseased mineralized tissues. Further optimization is needed to adapt the technique for human samples, considering differences in optical and mechanical properties.</p>","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":" ","pages":"152743"},"PeriodicalIF":1.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hormones and growth factors involved in supplying offspring: insights from fish to mammals.","authors":"Elisabeth Eppler, Alessandro Bilella, Karl Link, Helena D'Cotta, Jean-François Baroiller","doi":"10.1016/j.aanat.2025.152745","DOIUrl":"https://doi.org/10.1016/j.aanat.2025.152745","url":null,"abstract":"<p><p>A plethora of analogies to support energy provision and offspring nourishment have been posited between mammals and teleosts. This review provides a comprehensive overview of the intricate interactions between hormones and growth factors ranging from early egg development to feeding the newborn in mammals. The discussion encompasses hormones and growth factors in sexual development of male and female bony fish and then focuses on factors relevant during ovarian development and egg and yolk formation in female teleosts. The next chapter focuses on mechanisms to ensure calcium supply for embryo skeletal growth across vertebrate species and the respective maternal calcium mobilisation. Marine and freshwater fish possess divergent strategies for the acquisition of calcium, i.e., mineral homeostasis and osmoregulation. This review will focus primarily on actions of the growth hormone-insulin-like growth factor-system, the parathyroid hormone family, and other signalling factors and hormones. Prolactin is in the literature proposed as an evolutionary link between maternal nutrient supply in mammals, particularly calcium through lactation, and its ancestral role in regulating electrolyte and calcium uptake from the surrounding water in fish. The following section will present some hormones and growth factors in parental care in fish followed by signals in skeletal formation, lactation and calcium homeostasis in soil-egg-laying vertebrates, calcium metabolism in oviparous mammals and during embryonic and postnatal bone formation in placental mammals. Finally, hormones and factors relevant for the development of the mammalian breast are described.</p>","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":" ","pages":"152745"},"PeriodicalIF":1.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthetic composites versus calcium phosphate cements in bone regeneration: a narrative review.","authors":"Oana Bulagea Dima, A. Didilescu, C. Manole, Cornelis Pameijer, Claudiu Călin","doi":"10.1016/j.aanat.2024.152273","DOIUrl":"https://doi.org/10.1016/j.aanat.2024.152273","url":null,"abstract":"","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":"17 7","pages":"152273"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141051056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of rat vertebrae cortical bone microstructures using confocal Raman microscopy combined to tomography and electron microscopy.","authors":"S.A. Shah, H. Salehi, Vincent Cavaillès, Frédéric Fernandez, F. Cuisinier, P. Collart-Dutilleul, A. Desoutter","doi":"10.2139/ssrn.4397670","DOIUrl":"https://doi.org/10.2139/ssrn.4397670","url":null,"abstract":"BACKGROUND\u0000The rat vertebrae is a good model to study bone regeneration after implantation of biomaterials used to treat bone loss, a major problem in oral and dental surgery. However, the precise characterization of bone microstructures in the rat vertebrae has not been reported. Therefore, the aim of this study was to achieve the complete analysis of such bone, at different scales, in order to have a clear model of healthy bone for comparison with regenerated bone.\u0000\u0000\u0000METHODS\u0000In order to image the cortical bone of rat caudal vertebra, confocal Raman microscopy was combined with high resolution X-ray micro computed tomography (micro-CT), with scanning electron microscopy (SEM) using backscatter electron imaging and with more conventional histology coloration techniques. SEM and Raman microscopy were done in various regions of the cortical bone corresponding to external, middle and internal areas. The spongy bone was imaged in parallel. Micro-CT was performed on the whole vertebra to monitor the network of haversian canals in the cortical bone. Osteonic canals characteristics, and relative chemical composition were analysed in several regions of interest, in cortical and spongy bone. Five rats were included in this study.\u0000\u0000\u0000RESULTS\u0000On micro-CT images, differences in intensity were observed in the cortical bone, substantiated by SEM. Chemical analysis with Raman spectra confirmed the difference in composition between the different regions of the cortical and spongy bone. PCA and k-mean cluster analysis separated these groups, except for the external and middle cortical bone. Peak intensity ratio confirmed these results with a CO3 to ν2 PO4 ratio significantly different for the internal cortical bone. Grayscale images stack extracted from micro-CT showed that global architecture of cortical bone was characterized by a dense and complex network of haversian osteonic canals, starting from the surface towards the vertebrae center. The mean diameter of the canals was 18.4µm (SD 8.6µm) and the mean length was 450µm (SD 152µm). Finally, Raman reconstructed images of the lamellar bone showed an enlargement of the lamellar layer width, both in circumferential lamellar bone and around haversian canals.\u0000\u0000\u0000CONCLUSIONS\u0000Micro-CT and confocal Raman microscopy are good tools to complete classical analysis using optical and electron microscopy. The results and measurements presented in a rat model known for its small inter-individual differences provide the main characteristics of a mature bone. This study will allow the community working on this rat vertebrate model to have a set of characteristics, in particular on the structure of the haversian canals.","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":"5 1","pages":"152162"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81658095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"yThe influence of censorship laws on Viennese anatomy textbooks from the outgoing 18th Century until after the student revolution of 1848 in Austrian absolutism.","authors":"Sophia Bauer, Leo Maria Schaukal, W. Weninger","doi":"10.2139/ssrn.4330785","DOIUrl":"https://doi.org/10.2139/ssrn.4330785","url":null,"abstract":"INTRODUCTION\u0000Anatomy textbooks´ connection to the rigid censoring laws enacted by Habsburg rulers, was never sufficiently investigated. Using anatomy textbooks written at the University of Vienna, our article aims at investigating the influence of censorship laws on the anatomy textbooks in Vienna between 1786 and 1865.\u0000\u0000\u0000METHODS\u0000In our case study we compared legal text and archival sources (source material A) with seven prefaces of textbooks written by Viennese anatomists (source material B). The prefaces were comparatively investigated by applying the following questions based on source material A: (1) What motives for writing the textbooks were indicated by the anatomists in the prefaces? (2) What legal or other influences were mentioned as motives that point to a connection to the censorship regulations installed? (3) Referring to changing censorship guidelines is there a change in the mentioned audience?\u0000\u0000\u0000RESULTS\u0000Our results are that we found evidence for censorship regulations (source material A) in the prefaces (source material B). Also, the motives for writing those textbooks changed over time because of changing censorship regulations.\u0000\u0000\u0000CONCLUSION\u0000Our findings show that Viennese anatomy textbooks were part of the Austrian censorship laws in the investigated period with a timely correlation between the appointment as professor and the publication of the textbooks and prefaces (indirectly) referring to censorship laws. The academic tradition of writing textbooks arose from this system, when freedom of speech stood in opposition to the absolute Habsburg reign. Thus, when working with historical anatomy textbooks it is important to reflect on their censorship heritage.","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":"296 1","pages":"152129"},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76304471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior superior alveolar nerves contribute to sensation in the anterior teeth.","authors":"Sanako Makishi, Mikako Tanaka, Taichi Kobayashi, R. Tanaka, Takafumi Hayashi, H. Ohshima","doi":"10.21203/rs.3.rs-123843/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-123843/v1","url":null,"abstract":"BACKGROUND\u0000There is no available data on the occurrence rate of a converged alveolar canal, the detailed three-dimensional (3D) courses of alveolar canals/grooves (ACGs), or the contribution of each superior alveolar nerve to each area in the maxilla. This study aimed to clarify the 3D courses of ACGs, the relationship between ACGs and superior alveolar nerves, and the contribution of posterior superior alveolar nerves (PSANs) using computed tomography (CT) with histological analysis.\u0000\u0000\u0000METHODS\u0000During the gross anatomy course at Niigata University, we investigated nine human cadavers.\u0000\u0000\u0000RESULTS\u0000All anterior and posterior ACGs converged into the common alveolar canal, which contained blood vessels and several nerve bundles surrounded by perineurium, located at the nasal floor near the pyriform aperture. Histometrical analysis clarified that 16.3% of the nerve bundles in this canal were derived from PSANs, and 67% of the bundles were dispersed while they coursed down to the nasal floor. There seems to be no relationship between the density of nerve bundles in the canal and the number of remaining anterior teeth.\u0000\u0000\u0000CONCLUSIONS\u0000Data obtained from observing the detailed 3D courses of anterior and posterior ACGs, and their relationship with superior alveolar nerves, suggest that PSANs partially contribute to the nociception of the anterior teeth.","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":"28 1","pages":"151784"},"PeriodicalIF":0.0,"publicationDate":"2020-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72710710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Special Issue \"Human lymph vessels\".","authors":"E. Brenner","doi":"10.1016/j.aanat.2019.151441","DOIUrl":"https://doi.org/10.1016/j.aanat.2019.151441","url":null,"abstract":"","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":"521 1","pages":"151441"},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78856252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related changes of the human retinal vessels: possible involvement of lipid peroxidation.","authors":"T. Nag, M. Maurya, T. Roy","doi":"10.1016/j.aanat.2019.06.007","DOIUrl":"https://doi.org/10.1016/j.aanat.2019.06.007","url":null,"abstract":"","PeriodicalId":93872,"journal":{"name":"Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89398656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}