Acupuncture and herbal medicine最新文献

{"title":"An umbrella review of Lianhua Qingwen combined with Western medicine for the treatment of coronavirus disease 2019.","authors":"Kelu Yang, Jiaoyan Zhang, Liang Zhao, Luying Cheng, Yuanyuan Li, Yuchen Kang, Xiangyu Zhang, Yingying Kang","doi":"10.1097/HM9.0000000000000041","DOIUrl":"10.1097/HM9.0000000000000041","url":null,"abstract":"<p><p>Lianhua Qingwen combined with Western medicine (LHQW+WM) has been proposed as a viable treatment for coronavirus disease 2019 (COVID-19). Interestingly, umbrella reviews of systematic reviews (SRs), which provide the most comprehensive evidence, are the best evidence in evidence-based medicine. Therefore, an umbrella review of SRs that summarizes and evaluates the efficacy of LHQW+WM for COVID-19 is urgently required.</p><p><strong>Methods: </strong>Overall, 6 databases were used to conduct a comprehensive literature search from inception to January 22, 2022. The corrected covered area (CCA) was used to analyze the overlapping between SRs. Meta-analysis was conducted when that of the included SRs was inappropriate. A MeaSurement Tool to Assess Systematic Reviews (AMSTAR-2) was also employed to assess the quality of the included SRs.</p><p><strong>Results: </strong>In total, 12 SRs were identified, which included 12 unique primary studies. The included SRs ranged in quality from moderate to critically low and had an extremely high CCA (36.4%). Compared to conventional treatment, LHQW+WM showed efficacy concerning fatigue recovery [risk ratio (<i>RR</i>) = 1.69, 95% confidence interval (<i>CI</i>): 1.04-2.73, <i>n</i> = 2, <i>I</i>² = 0%], cough recovery (<i>RR</i> = 1.65, 95% <i>CI</i>: 1.09-2.51, <i>n</i> = 3, <i>I</i>² = 39.1%), and overall effective rates (<i>RR</i> = 1.17, 95% <i>CI</i>: 1.07-1.28, <i>n</i> = 3, <i>I</i>² = 17.5%).</p><p><strong>Conclusion: </strong>LHQW+WM may improve the clinical symptoms of patients with COVID-19; however, the results should be interpreted cautiously because of the rigorous processes in the included SRs.</p><p><strong>Graphical abstract: </strong>http://links.lww.com/AHM/A32.</p>","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"143-151"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/86/hm9-2-143.PMC9746252.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41164621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation of innate and adaptive immunity using herbal medicine: benefits for the COVID-19 vaccination.","authors":"Xuan Li,&nbsp;Nuttapong Wichai,&nbsp;Jiabao Wang,&nbsp;Xiuping Liu,&nbsp;Huimin Yan,&nbsp;Yu Wang,&nbsp;Mingchi Luo,&nbsp;Shengyuan Zhou,&nbsp;Kai Wang,&nbsp;Lin Li,&nbsp;Lin Miao","doi":"10.1097/HM9.0000000000000046","DOIUrl":"10.1097/HM9.0000000000000046","url":null,"abstract":"<p><p>Vaccination is a major achievement that has become an effective prevention strategy against infectious diseases and active control of emerging pathogens worldwide. In response to the coronavirus disease 2019 (COVID-19) pandemic, several diverse vaccines against severe acute respiratory syndrome coronavirus 2 have been developed and deployed for use in a large number of individuals, and have been reported to protect against symptomatic COVID-19 cases and deaths. However, the application of vaccines has a series of limitations, including protective failure for variants of concern, unavailability of individuals due to immune deficiency, and the disappearance of immune protection for increasing infections in vaccinated individuals. These aspects raise the question of how to modulate the immune system that contributes to the COVID-19 vaccine protective effects. Herbal medicines are widely used for their immune regulatory abilities in clinics. More attractively, herbal medicines have been well accepted for their positive role in the COVID-19 prevention and suppression through regulation of the immune system. This review presents a brief overview of the strategy of COVID-19 vaccination and the response of the immune system to vaccines, the regulatory effects and mechanisms of herbal medicine in immune-related macrophages, natural killer cells, dendritic cells, and lymphocytes T and B cells, and how they help vaccines work. Later in the article, the potential role and application of herbal medicines in the most recent COVID-19 vaccination are discussed. This article provides new insights into herbal medicines as promising alternative supplements that may benefit from COVID-19 vaccination.</p><p><strong>Graphical abstract: </strong>http://links.lww.com/AHM/A31.</p>","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"196-206"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/41/hm9-2-196.PMC9746255.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41165148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herbal medicine in the treatment of COVID-19 based on the gut-lung axis.","authors":"Qiaoyu He,&nbsp;Yumeng Shi,&nbsp;Qian Tang,&nbsp;Hong Xing,&nbsp;Han Zhang,&nbsp;Mei Wang,&nbsp;Xiaopeng Chen","doi":"10.1097/HM9.0000000000000038","DOIUrl":"10.1097/HM9.0000000000000038","url":null,"abstract":"<p><p>Respiratory symptoms are most commonly experienced by patients in the early stages of novel coronavirus disease 2019 (COVID-19). However, with a better understanding of COVID-19, gastrointestinal symptoms such as diarrhea, nausea, and vomiting have attracted increasing attention. The gastrointestinal tract may be a target organ of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The intestinal microecological balance is a crucial factor for homeostasis, including immunity and inflammation, which are closely related to COVID-19. Herbal medicine can restore intestinal function and regulate the gut flora structure. Herbal medicine has a long history of treating lung diseases from the perspective of the intestine, which is called the gut-lung axis. The physiological activities of guts and lungs influence each other through intestinal flora, microflora metabolites, and mucosal immunity. Microecological modulators are included in the diagnosis and treatment protocols for COVID-19. In this review, we demonstrate the relationship between COVID-19 and the gut, gut-lung axis, and the role of herbal medicine in treating respiratory diseases originating from the intestinal tract. It is expected that the significance of herbal medicine in treating respiratory diseases from the perspective of the intestinal tract could lead to new ideas and methods for treatment.</p><p><strong>Graphical abstract: </strong>http://links.lww.com/AHM/A33.</p>","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"172-183"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/81/hm9-2-172.PMC9746256.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post COVID-19 burden: focus on the short-term condition.","authors":"Fengwen Yang,&nbsp;Bo Pang,&nbsp;Xinyao Jin,&nbsp;Zhe Chen,&nbsp;Wentai Pang,&nbsp;Qingquan Liu,&nbsp;Junhua Zhang,&nbsp;Boli Zhang","doi":"10.1097/HM9.0000000000000036","DOIUrl":"10.1097/HM9.0000000000000036","url":null,"abstract":"The catastrophic pandemic of the coronavirus disease 2019 (COVID-19) has caused serious harm to human life and global social economy. As of June 13, 2022, there were more than 530 million confirmed cases of COVID19 and over 6.3 million deaths[1]. During the past 2 years, global studies on prevention and therapies for COVID19 have achieved a series of promising findings, including antiviral drugs (Remdesivir, Molnupiravir, Paxlovid) and monoclonal antibodies (Bamlanivimab and Etesevimab, Sotrovimab, Casirivimab and Imdevimab)[2]. World Health Organization (WHO) has validated 11 vaccines for the emergency use listing (EUL)[3]. As of June 13, 2022, more than 11.9 billion vaccine doses have been administered worldwide[1]. In China, integrated using of traditional Chinese medicine (TCM) and Western medicine is one of the highlights in fighting COVID-19. “Three formulations and three drugs” (Jinhua Qinggan granules, Lianhua Qingwen capsule, Xuebijing injection, and Qingfei Paidu decoction, Huashi Baidu decoction, Xuanfei Baidu decoction) have been approved by National Medical Products Administration (NMPA) as new drugs or adding indications for COVID-19[4]. The new drugs and vaccines had become effective weapons in the fight against the pandemic.","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"139-142"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/be/hm9-2-139.PMC9746249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptoms associated with nucleic acid turning-negative-time in COVID-19 patients?","authors":"Qiang Li,&nbsp;Lei Zhang,&nbsp;Limin Feng,&nbsp;Hongyuan Sun,&nbsp;Yan Ma,&nbsp;Xiaoya Liu,&nbsp;Cunzhong Shi,&nbsp;Mingchi Luo","doi":"10.1097/HM9.0000000000000037","DOIUrl":"10.1097/HM9.0000000000000037","url":null,"abstract":"Objective: To explore on the association between nucleic acid turning-negative-time and traditional Chinese medicine (TCM) symptoms in coronavirus disease 2019 (COVID-19) patients with the Omicron variant. Method: For this retrospective cross-sectional study, we enrolled 189 patients with COVID-19 (age 20–90 years) were included. multiple linear regression models were used to investigate the TCM symptoms affecting the nucleic acid turning-negative-time of COVID-19 patients, during the process of data analysis, taking with nucleic acid turning-negative-time as the dependent variable, and TCM symptoms as independent variables, and at the same time, sex, age, hypertension, diabetes, and coronary heart disease were as confounding variables. Results: The study found that the most common TCM symptoms of COVID-19 patients with Omicron were cough, dry throat, expectoration, fever, sore throat, pharyngeal itching, running nose, and nasal congestion. Regression analysis showed that the fit regressive equation showed a significant difference (F = 4.286, P < 0.001), R = 0.400, the adjusted R 2 = 0.123, and three variables in the regression equation showed significant difference (P < 0. 05). The results showed that nucleic acid turning-negative-time was mostly related to constipation, fever, and expectoration. If the patients had the symptoms of constipation, fever, and expectoration; that is, if patients showed these symptoms, the turning-negative-time of nucleic acid in patients with Omicron will be prolonged. Conclusions: Treatment based on symptoms for patients with constipation, fever, and expectoration may have important clinical significance for the COVID-19 patients with Omicron.","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"207-209"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/5f/hm9-2-207.PMC9746246.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41170049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Chinese medicine for promoting mental health of patients with COVID-19: a scoping review.","authors":"Zhaochen Ji, Haiyin Hu, Danlei Wang, Marco Di Nitto, Alice Josephine Fauci, Masayoshi Okada, Kai Li, Hui Wang","doi":"10.1097/HM9.0000000000000045","DOIUrl":"10.1097/HM9.0000000000000045","url":null,"abstract":"<p><p>This study aimed to systematically review and depict the current studies of traditional Chinese medicine for the mental health of patients with coronavirus disease 2019 (COVID-19).</p><p><strong>Methods: </strong>A scoping review was conducted by searching PubMed, Web of Science, CNKI, Wanfang database, VIP database, and SinoMed, with the retrieval time being from the establishment of the database to April 18, 2022. The basic information of the included studies, objective, design, types of patients, interventions, outcomes, etc., was reviewed and summarized narratively. Methodological quality was assessed using the Cochrane Risk of Bias assessment tool, the methodological index for non-randomized studies or the Newcastle-Ottawa scale.</p><p><strong>Results: </strong>We identified 30 traditional Chinese medicine (TCM) studies from six databases. Among them, finished randomized controlled trials (<i>n</i> = 16) accounted for most of the studies, followed by single-arm studies (n = 9). In terms of study theme, 20 studies defined the mental health of patients with COVID-19 as the research theme. Psychological assessment was included in the inclusion criteria (performed before participation) of nine studies, whereas the other studies only mentioned the mental outcomes. TCM interventions included TCM exercises (Yijinjing, Baduanjin, Liuzijue, Taichi), acupoint stimulation (auricular and body points), moxibustion, decoction, or granules based on TCM syndrome differentiation, decoction, or granules with fixed formulae (Baidu Jieduan granules, Xuanfei Baidu decoction, and Qingfei Paidu decoction), Chinese patent medicine (Jinhua Qinggan granules), TCM psychological therapy (TCM ideological therapy, TCM five-tone therapy, and TCM psychological sand table), and TCM nursing (dialectical care, dialectical diet, and psychological counseling). Anxiety and depression were the main outcomes evaluated in regard to mental health in patients with COVID-19. The limitations of methodological quality were predominantly from follow-up, blinding, and registration. Positive results were reported by 27 studies (90%, <i>n</i> = 30).</p><p><strong>Conclusion: </strong>We summarized the existing literature about the impact of TCM on mental health in patients with COVID-19. The number of studies evaluating the impact of TCM on mental health is encouraging, but overall methodological quality was low. Several TCM interventions warrant further evaluation, particularly among populations outside of China, for the purpose of establishing supporting evidence. More importantly, research with stronger methodological quality needs to be developed.</p><p><strong>Graphical abstract: </strong>http://links.lww.com/AHM/A36.</p>","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"184-195"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/30/1e/hm9-2-184.PMC9746253.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41176195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moxibustion for COVID-19: a systematic scoping review.","authors":"Meng Xia,&nbsp;Bo Pang,&nbsp;Shaowei Yi,&nbsp;Xinjue Shan,&nbsp;Shizhe Deng,&nbsp;Yinan Qin,&nbsp;Tao Jiang,&nbsp;Hai Lu","doi":"10.1097/HM9.0000000000000044","DOIUrl":"10.1097/HM9.0000000000000044","url":null,"abstract":"<p><p>Moxibustion has been widely used in the prevention and treatment of COVID-19. However, there is no systematic review of current topics and clinical findings on moxibustion for COVID-19. We conducted this scoping review to systematically summarize and analyze the themes and findings of published articles, and to provide an overview of current knowledge and practice of moxibustion for COVID-19.</p><p><strong>Methods: </strong>PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, SinoMed, Wan Fang Data, and VIP databases were searched from inception until April 2022. The relevant data were presented through bar graphs, structured tables, and figures along with descriptive statistics and analysis. This scoping review was conducted based on the PRISMA-ScR Checklist.</p><p><strong>Results: </strong>A total of 76 articles were reviewed: 47 reviews, 19 clinical research studies, seven systematic reviews (all were protocols), and three guidelines. All the studies were conducted by Chinese researchers and published from January 1, 2020 to March 14, 2022. The feasibility of moxibustion in the prevention and treatment of mild or moderate COVID-19 is based on the consensus of therapeutic mechanisms and effectiveness. The most adopted approach was the suspended and gentle moxibustion, and the most frequently applied or recommended acupoints were found to be ST36, CV8, CV6, CV4, CV12, GV14, BL13, LI4, ST25, and LR3.</p><p><strong>Conclusions: </strong>As a convenient and safe traditional Chinese medicine (TCM) therapy with its specific feature, moxibustion has been significantly effective at ameliorating mild or moderate symptoms among COVID-19 patients. Further large-scale, well-designed research and international cooperation are still warranted in clinical evaluations of moxibustion.</p><p><strong>Graphical abstract: </strong>http://links.lww.com/AHM/A35.</p>","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 3","pages":"162-171"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/aa/hm9-2-162.PMC9746254.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-line spectroscopy combined with multivariate analysis methods for endpoint determination in column chromatographic adsorption processes for herbal medicine","authors":"Cheng Jiang, Hai-bin Qu","doi":"10.1097/HM9.0000000000000035","DOIUrl":"https://doi.org/10.1097/HM9.0000000000000035","url":null,"abstract":"Objective: In a chromatographic cycle, the adsorption process is a critical unit operation that has a significant impact on downstream processes and, ultimately, the quality of the final products. The development of a rapid method to determine the endpoints of adsorption processes in a large-scale manufacturing is of substantial importance for herbal medicine (HM) manufacturers. Methods: In this study, the adsorption of saponins on a macroporous resin column chromatograph, a critical unit operation in Panax notoginseng (Burkill) F.H.Chen injection manufacturing, was considered as an example. The evaluation results of in-line ultraviolet and visible spectra combined with various multivariate analysis methods, including the moving block standard deviation (MBSD), difference between the moving block average and the target spectrum (DMBA-TS), soft-independent modeling of class analogy (SIMCA), and partial least-squares discriminant analysis (PLS-DA), were compared. Results: MBSD was unsuitable for adsorption processes. The relative standard errors of prediction between the predicted and experimental endpoints were 13.2%, 4.67%, and 5.71% using DMBA-TS, SIMCA, and PLS-DA, respectively. Conclusions: Among the considered analysis methods, SIMCA and PLS-DA were more effective for endpoint determination. The results of this study provide a more comprehensive overview of the effectiveness of various multivariate analysis methods to facilitate the selection of the most suitable method. This study was also conducive to address the issues of the in-line detection of adsorption endpoints to guide practical HM manufacturing. Graphical abstract: http://links.lww.com/AHM/A23","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"70 1","pages":"253 - 260"},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75336209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-fatigue effect from <i>Ginseng Radix et Rhizoma</i>: a suggestive and promising treatment for long COVID.","authors":"Xiangda Zhou, Keying Zhang, Lanbo Liu, Qianru Zhao, Ming Huang, Rui Shao, Yanyan Wang, Bin Qu, Yu Wang","doi":"10.1097/HM9.0000000000000033","DOIUrl":"10.1097/HM9.0000000000000033","url":null,"abstract":"<p><p>Two years after the coronavirus disease 2019 (COVID-19) outbreak, an increasing number of patients continue to suffer from long COVID (LC), persistent symptoms, and/or delayed or long-term complications beyond the initial 4 weeks from the onset of symptoms. Constant fatigue is one of the most common LC symptoms, leading to severely reduced quality of life among patients. <i>Ginseng Radix et Rhizoma</i>-known as the King of Herbs in traditional Chinese medicine-has shown clinical anti-fatigue effects. In this review, we summarize the underlying anti-fatigue mechanisms of <i>Ginseng Radix et Rhizoma</i> extracts and their bioactive compounds, with a special focus on anti-viral, immune remodeling, endocrine system regulation, and metabolism, suggesting that <i>Ginseng Radix et Rhizoma</i> is a potentially promising treatment for LC, especially in regard to targeting fatigue.</p>","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"2 2","pages":"69-77"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c0/ec/hm9-2-69.PMC9407182.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41157037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture and moxibustion treating lower urinary tract symptoms due to benign prostatic hyperplasia: a systematic review and network meta-analysis","authors":"Zhe Chen, Tao Jiang, Yingying Peng, Xiaoyu Qiang, Fengwen Yang, Haiyin Hu, Chunxiang Liu, Myeong Soo Lee","doi":"10.1097/HM9.0000000000000029","DOIUrl":"https://doi.org/10.1097/HM9.0000000000000029","url":null,"abstract":"Abstract Objective: Lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) affect the quality of life of elderly individuals. Acupuncture and moxibustion are used in the clinic in China for improving LUTS symptoms due to BPH. However, there is no evidence to suggest which is the best option. We compared the efficacy of acupuncture and moxibustion to provide evidence for clinical decision-making. Methods: PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wan Fang Data, and VIP databases were searched from inception to July 2020 to identify the randomized controlled trials (RCTs) of acupuncture and moxibustion for LUTS due to BPH. Two researchers filtered studies and extracted the information independently. This study conducted a network meta-analysis using the Bayesian random method. The interventions ranking was evaluated using the surface under the cumulative ranking curve (SUCRA). Results: We finally included 40 studies comprising 10 treating therapies and 3655 patients with LUTS caused by BPH. In terms of the International Prostate Symptom Score, maximum urinary flow rate, and quality of life, electroacupuncture (EA) (MD = −3.6, 95% credible interval [CrI] [−5.5, −1.8], very low certainty of evidence; MD = 2.2, 95% CrI [1.1, 3.3], low certainty of evidence; MD = −1.3, 95% CrI [−2.2, −0.43], very low certainty of evidence) may be consistently the optimal treatment compared with other interventions, with SUCRA values of 84%, 81%, and 89%, respectively. Conclusions: Of all treatments, EA may have the best efficacy with fewer adverse events for LUTS due to BPH. The quality of evidence supporting this result is low to very low certainty of the evidence due to limitations of primary studies; thus, more high-quality RCTs are needed for further evidence.","PeriodicalId":93856,"journal":{"name":"Acupuncture and herbal medicine","volume":"7 1","pages":"84 - 90"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85262436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}