Encarnación Antúnez-Estudillo , Laura Riera Tur , Andrés Caballero García
{"title":"Perichondritis and auricular cellulitis related to piercings as first manifestation of monkeypox","authors":"Encarnación Antúnez-Estudillo , Laura Riera Tur , Andrés Caballero García","doi":"10.1016/j.otoeng.2024.01.001","DOIUrl":"10.1016/j.otoeng.2024.01.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Pinna infections are usually due to <em>Staphylococcus aureus</em><span> infection. It is common for the patient to have had an earring in the area of infection. Monkeypox infection has gone from being an endemic infection to a worldwide health emergency.</span></p></div><div><h3>Case summary</h3><p>In this article we present five cases of monkeypox earring infection of the pinna and what common features we have seen that differentiate them from <em>Staphylococcus aureus</em> infection.</p></div><div><h3>Discussion</h3><p><span>Symptoms of monkeypox include general malaise, fever with uni- or bilateral lymphadenopathy<span>, and then the appearance within one or two days of skin lesions, we want to alert he otolaryngologist and the medical society to the possibility the diagnostic possibility of monkeypox </span></span>in patients with an auricular perichondritis.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 2","pages":"Pages 129-132"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Reda del Barrio , Alfredo García Fernández , Juan Francisco Quesada-Espinosa , María Teresa Sánchez-Calvín , Irene Gómez-Manjón , Olalla Sierra-Tomillo , Alexandra Juárez-Rufián , Joaquín de Vergas Gutiérrez
{"title":"Genetic diagnosis of childhood sensorineural hearing loss","authors":"Sara Reda del Barrio , Alfredo García Fernández , Juan Francisco Quesada-Espinosa , María Teresa Sánchez-Calvín , Irene Gómez-Manjón , Olalla Sierra-Tomillo , Alexandra Juárez-Rufián , Joaquín de Vergas Gutiérrez","doi":"10.1016/j.otoeng.2023.07.002","DOIUrl":"10.1016/j.otoeng.2023.07.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Congenital/early-onset sensorineural hearing loss (SNHL) is one of the most common hereditary disorders in our environment. There is increasing awareness of the importance of an etiologic diagnosis, and genetic testing with next-generation sequencing (NGS) has the highest diagnostic yield. Our study shows the genetic results obtained in a cohort of patients with bilateral congenital/early-onset SNHL.</p></div><div><h3>Materials and methods</h3><p>We included 105 children with bilateral SNHL that received genetic testing between 2019 and 2022. Genetic tests were performed with whole exome sequencing, analyzing genes related to hearing loss (virtual panel with 244 genes).</p></div><div><h3>Results</h3><p>48% (50/105) of patients were genetically diagnosed. We identified pathogenic and likely pathogenic variants in 26 different genes, and the most frequently mutated genes were <em>GJB2</em>, <em>USH2A</em> and <em>STRC</em>. 52% (26/50) of variants identified produced non-syndromic hearing loss, 40% (20/50) produced syndromic hearing loss, and the resting 8% (4/50) could produce both non-syndromic and syndromic hearing loss.</p></div><div><h3>Conclusions</h3><p>Genetic testing plays a vital role in the etiologic diagnosis of bilateral SNHL. Our cohort shows that genetic testing with NGS has a high diagnostic yield and can provide useful information for the clinical workup of patients.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 2","pages":"Pages 83-93"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aina Sansa , Cristina Valero , Albert Pujol , Blanca Sauter , Julia Gayà , Miquel Quer , Xavier León
{"title":"Prognostic capacity of PIV (pan-immune-inflammation value) in patients with head and neck squamous cell carcinoma","authors":"Aina Sansa , Cristina Valero , Albert Pujol , Blanca Sauter , Julia Gayà , Miquel Quer , Xavier León","doi":"10.1016/j.otoeng.2023.07.003","DOIUrl":"10.1016/j.otoeng.2023.07.003","url":null,"abstract":"<div><h3>Introduction</h3><p><span>The pan-immune-inflammation value (PIV), an index that results from the following ratio: (neutrophils × monocytes × platelets)/lymphocytes, has been proposed as a prognostic biomarker in different tumour models. The aim of this study is to analyse the prognostic capacity of PIV </span>in patients<span> with head and neck squamous cell carcinoma (HNSCC).</span></p></div><div><h3>Patients and methods</h3><p>Retrospective study of 1187 patients with HNSCC treated at our centre between 2000−2017. PIV value was obtained from an analysis performed within 3 weeks prior to the start of treatment.</p></div><div><h3>Results</h3><p><span>PIV value was significantly associated with toxic consumption (0.001), tumour location (0.0001), tumour extension (0.0001), and histological grade (0.016). Four categories were defined based on PIV value using a recursive partitioning analysis: category I: PIV < 136.3 (</span><em>n</em> = 118, 9.9%), category II: PIV 136.3–451.1 (<em>n</em> = 594, 50.0%), category III: PIV 451.1−1,141.2 (<em>n</em> = 357, 30.1%), and category IV: PIV > 1141.2 (<em>n</em><span> = 118, 9.9%). A significant and ordered decrease in disease-specific survival was observed as the PIV category increased. This decrease in survival was independent of the type of treatment, tumour extension, or location of the primary tumour. The PIV category was and independent prognostic factor of disease-specific survival in a multivariable study.</span></p></div><div><h3>Conclusions</h3><p>PIV is a prognostic biomarker in patients with HNSCC.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 2","pages":"Pages 94-101"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serafín Sánchez-Gómez , Elena Molina-Fernández , María Eugenia Acosta Mosquera , José María Palacios-García , Fernando López-Álvarez , María Sonia de Juana Morrondo , Beatriz Tena-García
{"title":"Tracheotomy versus tracheostomy, the need for lexicographical clarification","authors":"Serafín Sánchez-Gómez , Elena Molina-Fernández , María Eugenia Acosta Mosquera , José María Palacios-García , Fernando López-Álvarez , María Sonia de Juana Morrondo , Beatriz Tena-García","doi":"10.1016/j.otoeng.2023.06.011","DOIUrl":"10.1016/j.otoeng.2023.06.011","url":null,"abstract":"<div><p>In the healthcare field, the terms “traqueotomía” and “traqueostomía” are frequently used, often leading to confusion among professionals regarding the appropriate definition for each term or which one should be considered more correct in specific cases. A search was conducted for the terms “traqueotomía” and “traqueostomía” in general Spanish-language dictionaries such as the Dictionary of the Royal Spanish Academy (DRAE) and the Historical Dictionary of the Spanish Language of the Royal Spanish Academy (DHLE), as well as for the English terms “tracheotomy” and “tracheostomy” in English general dictionaries like the Oxford Dictionary, the Cambridge Dictionary, and the Collins English Dictionary. Additionally, searches were performed in medical dictionaries in both Spanish, specifically the Dictionary of Medical Terms of the National Academy of Medicine (DTM), and English, including the Farlex Dictionary. The terms were also explored using the Google search engine. Definitions were analyzed from both lexicographical and etymological perspectives. Definitions found in general dictionaries, in both Spanish and English, were found to be imprecise, limited, and ambiguous, as they mixed outdated indications with criteria that deviated from etymology. In contrast, definitions in medical dictionaries in both languages were more aligned with etymology. “Traqueotomía” strictly identifies the surgical procedure of creating an opening in the anterior face of the trachea. “Traqueostomía” identifies the creation of an opening that connects the trachea to the exterior, involving a modification of the upper airway by providing an additional entry for the respiratory pathway. “Traqueostomía” becomes the sole means of entry to the airway in total laryngectomies. Both terms can be used synonymously when a traqueotomía culminates in a traqueostomía. However, it is not appropriate to use the term “traqueostomía” when the procedure concludes with the closure of the planes and does not result in the creation of a stoma. Traqueostomas can be qualified with adjectives indicating permanence (temporary/permanent), size (large/small), shape (round/elliptical), or depth, without being linked to any specific disease or surgical indication. Not all permanent traqueostomas are the result of total laryngectomies, and they do not necessarily have an irreversible character systematically.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 2","pages":"Pages 73-82"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In response to the letter to the editor “Comments to: Manifestations ENT manifestations in monkeypox”","authors":"Berta Alegre , Isabel Vilaseca","doi":"10.1016/j.otoeng.2023.10.008","DOIUrl":"10.1016/j.otoeng.2023.10.008","url":null,"abstract":"","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 2","pages":"Page 135"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139827586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic ablation for glottic cancer in a patient with temporomandibular joint ankylosis","authors":"Petru Gurău , Eusebiu Sencu , Sergiu Vetricean","doi":"10.1016/j.otoeng.2023.09.003","DOIUrl":"10.1016/j.otoeng.2023.09.003","url":null,"abstract":"","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 1","pages":"Pages 67-69"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10311182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gian Antonio Bertoli , Marco De Vincentiis , Edoardo Covelli , Haitham H. Elfarargy
{"title":"The novel retro-conchal approach for middle ear surgeries: Our experience in 196 patients","authors":"Gian Antonio Bertoli , Marco De Vincentiis , Edoardo Covelli , Haitham H. Elfarargy","doi":"10.1016/j.otoeng.2023.06.009","DOIUrl":"10.1016/j.otoeng.2023.06.009","url":null,"abstract":"<div><h3>Background</h3><p>This study aimed to describe a new proposed retro-conchal approach for middle ear surgery and to evaluate its advantages and postoperative impact.</p></div><div><h3>Methodology</h3><p><span><span>A retrospective case-series study was held at a tertiary university hospital from March 2008 to April 2022. We included 196 adult patients who were candidates for middle ear surgery because of chronic otitis media. The retro-conchal approach entailed a skin </span>incision<span><span> on the medial conchal surface 1 cm anterior to the auricular sulcus. It allowed the harvesting of the required size of conchal cartilage and temporalis fascia through the same incision with access into the middle ear and complete exposure to the mastoid process. In addition, we evaluated the use of this approach in </span>tympanoplasty, including </span></span>cholesteatoma surgeries with at least one-year postoperative follow-up.</p></div><div><h3>Result</h3><p><span><span>The long-term follow-up (22.9 ± 6.37 months) revealed that most operated cases (89%) did not develop postoperative sequelae related to this approach. On the other hand, 22 patients (11%) developed </span>adverse outcomes, with a statistically significant difference regarding adverse outcomes as the </span><em>P</em>-value <0.001.</p></div><div><h3>Conclusion</h3><p>According to our experience with a relatively large number of patients, the retro-conchal technique was practical for various middle ear surgeries. It allowed optimal access to different middle ear areas and obtaining large-sized conchal cartilage and temporalis fascia (if needed) through the same incision without needing extra surgical steps. In addition, it was a safe maneuver without significant adverse outcomes in the long-term follow-up.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 1","pages":"Pages 40-46"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10311185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara Espina González , Antonio Morant Ventura , Ignacio Pla Gil , María Aragonés Redó , Tomás Pérez Carbonell , Jaime Marco Algarra
{"title":"Variation of electrical impedance over 5 years post-implantation and relationship with the maximum comfort level (MCL) in adults with cochlear implants","authors":"Clara Espina González , Antonio Morant Ventura , Ignacio Pla Gil , María Aragonés Redó , Tomás Pérez Carbonell , Jaime Marco Algarra","doi":"10.1016/j.otoeng.2024.01.004","DOIUrl":"10.1016/j.otoeng.2024.01.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The maximum comfort level (MCL), threshold level (THR) and electrical impedance change in the postoperative period<span> of the cochlear implant for months until they stabilize. The objective of this article is to establish the variation during 5 post-surgical years of impedance, and its relationship with MCL in unilaterally implanted adults.</span></p></div><div><h3>Methods</h3><p>Retrospective study over 5 years, with 78 adult patients implanted with MED-EL in a tertiary hospital from the year 2000 to 2015. The variation in impedance, MCL and the relationship between them were analyzed in basal (9–12), medial (5–8) and apical electrodes (1–4), performing an inferential ANOVA analysis of repeated measures with comparisons between consecutive times, corrected with Bonferroni criteria.</p></div><div><h3>Results</h3><p>33 men (42.3%) and 45 women (57.7%), with a mean age of 52.7<!--> <!-->±<!--> <!-->14.6 years. “Stability” was considered the time of follow-up without statistically significant differences between one visit and the next. Changes in impedance in medial electrodes ceased to be statistically significant at 3 months, and in apicals at 6 months, with mean values of 5.84 and 6.43<!--> <!-->kΩ. MCL stabilized at 2 years in basal and apical electrodes, and at 3 years in medial, with mean values of 24.9, 22.7, and 25.6<!--> <!-->qu. There was a correlation between MCL and impedance in medium electrodes up to 3 months and in apical ones up to one year.</p></div><div><h3>Conclusions</h3><p>Electrical impedance drops significantly in medial and apical electrodes up to 3 and 6 months. MCL increases significantly up to two years. Impedance is related to MCL up to 6 months.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 1","pages":"Pages 23-30"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139471380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Ciorba, Virginia Fancello, Beatrice Sacchet, Michela Borin, Nicola Malagutti, Chiara Bianchini, Francesco Stomeo, Stefano Pelucchi
{"title":"Acute mastoiditis in cochlear implanted children: A single-centre experience","authors":"Andrea Ciorba, Virginia Fancello, Beatrice Sacchet, Michela Borin, Nicola Malagutti, Chiara Bianchini, Francesco Stomeo, Stefano Pelucchi","doi":"10.1016/j.otoeng.2023.09.004","DOIUrl":"10.1016/j.otoeng.2023.09.004","url":null,"abstract":"<div><h3>Background</h3><p>Acute mastoiditis<span> (AM) is the most common complication of acute otitis media<span> and primarily affects children under the age of two; current data on its prevalence in paediatric patients with cochlear implant (CI) are still scant. Proper management of AM in CI children is crucial in order to avoid the implications (financial and emotional) of an explant.</span></span></p><p>Aim of this paper is to describe the cases of AM occurred among young patients with CI in follow up at our department, also in order to evaluate its prevalence, potential predisposing factors, clinical course and therapeutic strategies.</p></div><div><h3>Patients and methods</h3><p>Retrospective study. Medical records<span> of all paediatric patients with CI, who had at least one year of follow-up, were searched aiming to identify those who developed AM, from January 1st 2002 to January 31st 2022. The following data were collected and analysed: demographic features, implant type and side, interval between CI surgery and AM, treatment, laboratory tests, clinical course, vaccination history, associated diseases.</span></p></div><div><h3>Results</h3><p>AM was developed by six (1.3%) of the 439 children with CI (541 implanted ears). In total, 9 episodes (2.05 %) were recorded, as three patients reported two consecutive infections. Average time interval between CI surgery, to the first or only AM diagnosis, was 13.8 months (range 3–30 months). Furthermore, 3/6 of patients had a history of recurrent acute otitis media; 2/6 an autism spectrum disorder<span><span>, associated to a combined immune deficiency in one case. All patients were hospitalized and promptly treated by intravenous antibiotic therapy; 4/6 also underwent a </span>mastoidectomy. CI was not explanted in any cases of this series.</span></p></div><div><h3>Conclusions</h3><p>Over a 20-year period, AM rate in CI children was 1.3%, which is consistent with the current literature rates of 1–4.7%. All cases were successfully treated, preserving the integrity of the device. In our experience, the early parenteral antibiotic therapy and, when necessary, surgical treatment were adequate to eradicate the infection.</p></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"75 1","pages":"Pages 17-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10362030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}