World journal of gastroenterology, hepatology and endoscopy最新文献

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High-dose rate brachytherapy for palliative care in rectal cancer: A case with a complete response, followed by a rare complication 直肠癌姑息治疗的高剂量率近距离放疗:一例完全缓解,随后出现罕见并发症
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000178
Aurélia Alati, Leobon Sophie, C. Pierre
{"title":"High-dose rate brachytherapy for palliative care in rectal cancer: A case with a complete response, followed by a rare complication","authors":"Aurélia Alati, Leobon Sophie, C. Pierre","doi":"10.15761/ghe.1000178","DOIUrl":"https://doi.org/10.15761/ghe.1000178","url":null,"abstract":"","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74153677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual cause of deranged liver function tests: From paracetamol to Pompe’s 肝功能检查异常的不寻常原因:从扑热息痛到庞培
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000182
R. Rajendram, R. Parker
{"title":"An unusual cause of deranged liver function tests: From paracetamol to Pompe’s","authors":"R. Rajendram, R. Parker","doi":"10.15761/ghe.1000182","DOIUrl":"https://doi.org/10.15761/ghe.1000182","url":null,"abstract":"AMD (glycogen storage disease type 2) or Pompe’s disease is an autosomal recessive disorder with an estimated incidence of approximately 1:40,000 [1,2]. There is a deficiency of the enzyme α1,4 glucosidase which breaks down glycogen in cell lysosomes. Glycogen accumulates within lysosomes and disrupts cellular function. This affects skeletal muscle including the diaphragm. The presentation is usually insidious with gradually increasing peripheral muscle weakness or respiratory failure. Prognosis is highly variable and depends on the gene mutation and enzyme activity. As no cure is available, supportive therapies such as noninvasive ventilation and genetic screening of family members are the cornerstones of management. However, enzyme replacement therapies have been developed and the results of initial studies are promising [3,4].","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88009090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospital zero hepatitis: Easy and useful! 医院零肝炎:简单实用!
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/GHE.1000180
Remy André-Jean
{"title":"Hospital zero hepatitis: Easy and useful!","authors":"Remy André-Jean","doi":"10.15761/GHE.1000180","DOIUrl":"https://doi.org/10.15761/GHE.1000180","url":null,"abstract":"Introduction: 59000 hepatitis C patients were unknown or not followed in France. In 2017, 81% of our “new” patients have already been hospitalized, especially in emergency units. Hepatitis C was noted in their file as other medical histories like appendicitis or shin fracture! Drug users came one to twelve times per year in hospital for different reasons, but never for hepatitis care. No HCV care was proposed to these patients after other health problem resolution. Objective: To identify HCV patients coming to our hospital by using nurses of every service for a goal of zero hepatitis hospital. Methodology: Our hepatitis specialized nurse did training sessions of nurses in every unit of our hospital about hepatitis screening, diagnosis and treatment and when to call hepatitis nurse if they had HCV positive patient and gave specific flyers and posters. Results: In 15 months, hepatitis nurse did training sessions in 15 units of our hospital, including 92 nurses. We received 58 calls about 52 patients with hepatitis C; 50/58 patients were current or formers drug users, 32 patients are known as negative viral load, spontaneously or after antiviral treatment; 20 had positive viral load and took care by our team; 13 started immediately DAA. All drug users had also risk reduction session. Conclusion: Hospital nurses training was easy to set up and cheap and useful to detect new patients or known patients without medical care, specially drug users. Same project could be done in every hospital. *Correspondence to: Remy Andre-Jean, Mobile Hepatitis Team, Perpignan Hospital, France, Tel: 0468616137; E-mail: andre.remy@ch-perpignan.fr","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86326326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic removal of impacted Dormia basket: The post-cut procedure 内窥镜切除嵌塞睡眠篮:切后手术
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000185
W. Ferjaoui, Mohamed Ali Chaouech, Wafa B Hmida, R. Bouali, W. Ghariani, H. Jerraya, R. Nouira
{"title":"Endoscopic removal of impacted Dormia basket: The post-cut procedure","authors":"W. Ferjaoui, Mohamed Ali Chaouech, Wafa B Hmida, R. Bouali, W. Ghariani, H. Jerraya, R. Nouira","doi":"10.15761/ghe.1000185","DOIUrl":"https://doi.org/10.15761/ghe.1000185","url":null,"abstract":"Endoscopic procedures are widely used for the management of bile duct stones. Pancreatitis, haemorrhage, cholangitis and intestinal perforation are the most commonly reported complications. Impaction of stone-retrieving devices such as Dormia basket is rare. It can be removed using a smaller basket, balloons, percutaneous transhepatic removal, laparoscopic retrieval or even through laparotomy. In our case, it was feasible and safe using the post cut technique which is a type of a second biliary sphincterotomy performed after a previous sphincterotomy in order to enlarge the papillary orifice and to extract the impacted Dormia basket. *Correspondence to: Wael Ferjaoui, Department of Surgery B23, Charles Nicolle Hospital, Tunisia, Tel: +216 52430099; E-mail: farjaouiwael4@gmail.com key words: common bile duct stone, impacted Dormia basket, post cut Received: July 15, 2019; Accepted: August 01, 2019; Published: August 05, 2019 Introduction Endoscopic management is the first line therapy of common bile duct stones [1]. In most cases, they are successfully extracted with Endoscopic Retrograde Cholangiopancreatography (ERCP) and endoscopic sphincterotomy (ES) using a Dormia basket or balloon catheters [1]. This endoscopic treatment ensures less morbidity and mortality then surgery [1]. The most common complications of endoscopic treatment are pancreatitis, bleeding and perforation [2]. Recognizing other less common events like Dormia basket impaction is important in order to prevent disastrous outcomes. The aim of this article is to report a case of Dormia basket impaction that could be managed using an endoscopic technique called the post-cut procedure in order to prove its efficiency and safety.","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80117701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A rare cause of abdominal pain in a child: Mesenteric panniculitis 一种罕见的引起儿童腹痛的原因:肠系膜性肠膜炎
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000181
Ishak Abdurrahman Isik
{"title":"A rare cause of abdominal pain in a child: Mesenteric panniculitis","authors":"Ishak Abdurrahman Isik","doi":"10.15761/ghe.1000181","DOIUrl":"https://doi.org/10.15761/ghe.1000181","url":null,"abstract":"","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87078163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe hepatopathy and celiac disease 严重肝病和乳糜泻
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/GHE.1000175
M. Firwana, I Benelberhdadi, A Aomari, Ajana Fz
{"title":"Severe hepatopathy and celiac disease","authors":"M. Firwana, I Benelberhdadi, A Aomari, Ajana Fz","doi":"10.15761/GHE.1000175","DOIUrl":"https://doi.org/10.15761/GHE.1000175","url":null,"abstract":"Of a total of 248 cases of celiac disease observed in our department, 78 cases (31.5%) had chronic associated liver disease, including 05 cases of severe liver disease. There are 3 women and 2 men with a sex ratio F/H of 1.5, the average age was 35 years [25-57]. The diagnosis of celiac disease was made before the appearance of chronic liver disease in 04 patients with an average delay of 9.5 years, whereas only one patient had a chronic liver disease diagnosed 05 years before the discovery of celiac disease. The reason for consultation was mainly malabsorption diarrhoea (5 cases). The physical examination found a syndrome of portal hypertension in 3 cases and is normal in 2 cases. In the biology, there was anaemia in 4 cases including one case of pan cytopenia, one hepatic cytolysis in 4 cases. The abdominal ultrasound showed a chronic hepatic appearance +/sign of HTP in 4 cases and normal in one case. The etiological balance of cytolysis was negative (B, C, autoimm, overload). Upper digestive endoscopy showed a rarefaction of duodenal folds in 3 cases, with signs of HTP in all patients. The histopathological study of the biopsies showed intraepithelial lymphocytosis > 30% with villous atrophy in all patients. Antitransglutaminase antibodies were positive in 04 patients and negative in 01 cases. The liver biopsy puncture showed severe fibrosis (F3) in 03 cases and cirrhosis (F4) in 2 cases. All our patients are on gluten-free diet, with symptomatic treatment of portal hypertension. The evolution was marked by a stabilization of chronic liver disease and its complications. One case presented ascitic decompensation for poor compliance with the glutenfree diet. No case of CHC has been noted in our series.","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79878458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increased liver tests and hepatomegaly: Is there an increased prevalence of Gaucher disease in this population? 肝检查增加和肝肿大:戈谢病在这一人群中的患病率是否增加?
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000173
Elkilic O, Laeremans H, Lasser L, Mboti F
{"title":"Increased liver tests and hepatomegaly: Is there an increased prevalence of Gaucher disease in this population?","authors":"Elkilic O, Laeremans H, Lasser L, Mboti F","doi":"10.15761/ghe.1000173","DOIUrl":"https://doi.org/10.15761/ghe.1000173","url":null,"abstract":"The screening was performed using a dried bloodspot on Whatman paper 906. The enzymes were measured with a LC-MS-MS method according to the protocol of CDC (Centre of disease control and prevention). The method was validated for stability of the enzymes in the dried blood spot and variability. All runs were controlled with external controls from CDC and blanc correction was adapted. Cut-off values were 3 umol/l/h has been proposed and used by the reference center.","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80605893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A seriously overlooked hemorrhage following paracentesis managed by trans-arterial embolization of the deep circumflex iliac artery: A case report 经动脉栓塞治疗旋髂深动脉穿刺后严重被忽视的出血:一例报告
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000174
M. Habib, M. Hillis, Khaled Hani Alkhodari
{"title":"A seriously overlooked hemorrhage following paracentesis managed by trans-arterial embolization of the deep circumflex iliac artery: A case report","authors":"M. Habib, M. Hillis, Khaled Hani Alkhodari","doi":"10.15761/ghe.1000174","DOIUrl":"https://doi.org/10.15761/ghe.1000174","url":null,"abstract":"","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"234 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75916059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Motivators, barriers and incidence of screening for celiac disease in first degree relatives at 14 years after initial screening 首次筛查后14年一级亲属乳糜泻筛查的动机、障碍和发病率
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000179
Anne R Lee, S. Keats, R. Wolf, B. Lebwohl, E. Ciaccio, P. Green
{"title":"Motivators, barriers and incidence of screening for celiac disease in first degree relatives at 14 years after initial screening","authors":"Anne R Lee, S. Keats, R. Wolf, B. Lebwohl, E. Ciaccio, P. Green","doi":"10.15761/ghe.1000179","DOIUrl":"https://doi.org/10.15761/ghe.1000179","url":null,"abstract":"Background: The prevalence of celiac disease (CD) is nearly 1% of the general population, but higher among first-degree relatives. Current guidelines recommend testing for symptomatic first-degree relatives and consideration of testing for asymptomatic first-degree relatives. We sought to determine incidence of follow-up testing, as well as facilitators and barriers, in first-degree relatives who participated in a Family Screening Day 2005. Method: The 272 first-degree relatives who provided initial contact information were invited to participate in this study. A self-administered questionnaire queried retesting, conversion, additional diagnosis, and relationship to the index family member. Data was analyzed using descriptive statistics. Results: Responses (n=34, 13% of the originally screened cohort) were received, 17 participants met inclusion criteria and completed the survey. The participants were predominately female (71%) and between the ages of 26-55 (59%) at follow-up. Thirteen (77%) of the 17 participants tested negative in 2005. The majority (N=9, 69%) of those initially testing negative had not been retested nearly 14 years later. Barriers to retesting were the belief that retesting was not necessary (78%) and lack of symptoms (22%). Presence of symptoms were a motivating factor for the 3 of the four individuals who did retest (75%). Conclusion: We found a low rate of retesting of first-degree relatives despite recommendations. In the light of increased incidence of celiac disease in first-degree relatives, as well as the increased risk of developing comorbidities if celiac disease is left untreated, the results of this study indicate the need for increased awareness of testing recommendations among first-degree relatives. *Correspondence to: Anne R Lee, Celiac Disease Center, Columbia University Irving Medical Center, Harkness Pavilion, 180 Fort Washington Avenue, New York, NY, USA, Tel: (212) 305-5590; E-mail: arl2004@cumc.columbia.edu","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83397567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune diseases associated with autoimmune hepatitis in a series of 21 cases 自身免疫性疾病伴自身免疫性肝炎21例
World journal of gastroenterology, hepatology and endoscopy Pub Date : 2019-01-01 DOI: 10.15761/ghe.1000191
Bennani Gk, Benelbarhdadi I, Bourehma M, Berhili C, Lagdali N, Ajana Fz
{"title":"Autoimmune diseases associated with autoimmune hepatitis in a series of 21 cases","authors":"Bennani Gk, Benelbarhdadi I, Bourehma M, Berhili C, Lagdali N, Ajana Fz","doi":"10.15761/ghe.1000191","DOIUrl":"https://doi.org/10.15761/ghe.1000191","url":null,"abstract":"","PeriodicalId":93828,"journal":{"name":"World journal of gastroenterology, hepatology and endoscopy","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79664763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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