{"title":"Effect of regional anesthesia on pain sensitization after surgery: New concepts","authors":"Laurent Bollag MD, Philippe Richebé MD, PhD","doi":"10.1053/j.trap.2013.03.002","DOIUrl":"10.1053/j.trap.2013.03.002","url":null,"abstract":"<div><p><span>Severe postoperative pain and wound </span>hyperalgesia<span>, a clinical sign of central sensitization, are risk factors for the development of chronic postsurgical pain. This article describes the neuronal changes that surgical pain and possibly high opioid doses cause in the central nervous system<span>. It also relates how regional anesthesia might oppose these changes and block both the pain sensitization and the pain chronification following surgery.</span></span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 3","pages":"Pages 127-130"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Tornero Tornero MD , Luis Aliaga Font MD, PhD
{"title":"Training on regional anesthesia—From neurostimulation to ultrasound","authors":"Carlos Tornero Tornero MD , Luis Aliaga Font MD, PhD","doi":"10.1053/j.trap.2013.03.003","DOIUrl":"10.1053/j.trap.2013.03.003","url":null,"abstract":"<div><p><span>The number of procedures carried out with regional anesthesia techniques is increasingly higher; this applies not only to the anesthetic act itself but also includes </span>postoperative analgesia<span>, with the added advantage of the possibility of being a tool that prevents pain from becoming chronic. Anesthesiologists should be adequately trained in neurostimulation and ultrasound regional anesthesia techniques. The progress of ultrasound over the last few years has pushed both anatomical cutaneous references and basic pharmacologic knowledge into the background, so as to focus essentially on ultrasound visualization. This article reviews the different elements required for a good training in regional anesthesia (phantoms, simulators, tutorials, corpse workshop, etc) without disregarding neurostimulation, and it focuses on ultrasound as the main nerve location tool for the performance of regional anesthesia techniques.</span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 3","pages":"Pages 131-135"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vicente Roqués Escolar MD , Ana Isabel Sánchez Amador MD , Mari Carmen Martínez-Segovia MD
{"title":"Is ultrasound essential for regional anesthesia in children?","authors":"Vicente Roqués Escolar MD , Ana Isabel Sánchez Amador MD , Mari Carmen Martínez-Segovia MD","doi":"10.1053/j.trap.2013.03.008","DOIUrl":"10.1053/j.trap.2013.03.008","url":null,"abstract":"<div><p>According to systematic reviews<span><span><span> performed on adults, ultrasound provides moderate advantages in latency time reduction and block quality. Whether it really reduces the number of complications at the expense of less vascular puncturing, less diaphragm paralysis, and less pleural puncturing, together with lower doses of </span>local anesthetic used, is a controversial question. Neither is there evidence that ultrasound achieves a higher rate of success than traditional techniques. Pediatric patients have special characteristics that differentiate them from adult patients, so the existing studies and their results should not be extrapolated. Ultrasound has a series of advantages: real-time visualization of our target or infiltration of anatomical plane; a view of the needle performing the puncture; and continuous monitoring of spreading of the local anesthetic. Few techniques satisfy so many requirements for adoption by the medical practice, but trials proving that this is an essential technique for </span>pediatric<span> regional anesthesia are scarce. However, ultrasound has shown to be at least as efficient and as safe as traditional techniques and should therefore be routinely used in pediatric regional anesthesia.</span></span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 3","pages":"Pages 158-163"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.03.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Hernando Sáez MD , Carlos Tornero Tornero MD , Vicente Roqués Escolar MD , Francisco Hernández Méndez MD , Luis Aliaga Font MD, PhD
{"title":"Development of complications in ultrasound-guided regional anesthesia vs neurostimulation","authors":"Jorge Hernando Sáez MD , Carlos Tornero Tornero MD , Vicente Roqués Escolar MD , Francisco Hernández Méndez MD , Luis Aliaga Font MD, PhD","doi":"10.1053/j.trap.2013.03.007","DOIUrl":"10.1053/j.trap.2013.03.007","url":null,"abstract":"<div><p><span>The use of peripheral nerve block<span> techniques has significantly increased over the last two decades; as a consequence, development of complications has also increased. Neurostimulation has been the technique of choice for locoregional anesthesia for many years and has even been considered the gold standard. Compared with location by means of paresthesia, this technique reduces the potential risk of postoperative </span></span>neuropathy<span><span>, as it limits any direct contact between the needle and the nerve structure. Neurostimulation provides high efficacy with a minimum complication rate; currently, however, as ultrasound provides real time visualization of the nerve, needle and local anesthetic distribution relationship, the use of neurostimulation is less prevalent. Additionally to an apparent improvement of ultrasound-guided peripheral block success rate, there are also many trials available promoting the decrease of </span>neurologic complications. Thus the unavoidable question comes up: is ultrasound the quality gold standard for locoregional anesthesia today? Should we rule out formerly used techniques? The current evidence for maintaining routine and exclusive use of ultrasound over any other peripheral nerve block method is limited. So, why not use all anesthetic techniques available to us, that is neurostimulation, injection pressure control, and ultrasound, to bring the complication rate down?</span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 3","pages":"Pages 152-157"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.03.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-frequency spinal cord stimulation: An emerging treatment option for patients with chronic pain","authors":"Ricardo Vallejo MD, PhD","doi":"10.1053/j.trap.2012.12.002","DOIUrl":"10.1053/j.trap.2012.12.002","url":null,"abstract":"<div><p><span><span>Chronic pain is a complex syndrome estimated to affect over 100 million Americans. Pharmaceutical-based therapy, including the use of opioids, is widely accepted as a primary treatment strategy but is associated with addiction, overdose, and diversion risk. </span>Spinal cord stimulation<span> (SCS) is a well-established, device-based alternative for pain management. Though effective in treating leg pain, traditional SCS has been much less effective at achieving long-term back-pain relief. In addition, stimulation with traditional SCS often leads to tingling sensations and inadvertent postural-related shocks that many patients find unpleasant. A newly developed SCS system (Nevro Corp., Menlo Park, CA) shows promise in addressing these limitations. This new device is similar to traditional SCS systems but is able to stimulate at much higher frequencies, up to 10</span></span> <span>kHz. Prospective clinical studies of high-frequency SCS (HF-SCS) suggest improved effectiveness in treating chronic low-back pain and other types of pain that often do not respond well to traditional SCS. In addition, HF-SCS appears capable of delivering pain relief without paresthesia, both simplifying the implant procedure and improving patient satisfaction. The system is currently undergoing study in a multicenter, randomized controlled clinical trial in the United States. If the results are positive, HF-SCS could represent an important advancement in the treatment of chronic pain.</span></p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 2","pages":"Pages 106-112"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2012.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58055325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Tyler Perryman MS, MBA, Benjamin Speck MS, Carlos Montes Garcia MD, Ralph Rashbaum MD
{"title":"Injectable spinal cord stimulator system: Pilot study","authors":"Laura Tyler Perryman MS, MBA, Benjamin Speck MS, Carlos Montes Garcia MD, Ralph Rashbaum MD","doi":"10.1053/j.trap.2013.02.006","DOIUrl":"10.1053/j.trap.2013.02.006","url":null,"abstract":"<div><p><span><span>Spinal cord stimulation<span> (SCS) is widely used for relief of chronic back and limb pain. However, numerous adverse events pose a hindrance to the widened acceptability of the treatment. A prospective, nonrandomized </span></span>cohort study was conducted to compare the efficacy of a wirelessly powered SCS novel system with commercial SCS systems. Each of 12 patients were serially implanted with a Medtronic 1 × 8 SCS trial lead and a Stimwave Freedom trial lead for a 1-day evaluation. Patients were asked to report on pain relief, paresthesia coverage, paresthesia intensity, and paresthesia comfort. Ten of the 12 patients successfully underwent the trial whereas the remaining 2 procedures were terminated because of operating-equipment failures. Of the successful patients, all reported good pain relief and paresthesia for each device. The average pain reduction was reported as 80% for the Stimwave system and 66% for the Medtronic system. The average paresthesia coverage was 91% and 77%, respectfully. Differences in the averages reported by patients can be attributed to the fact that no randomization was designed in the study. The study showed that wirelessly powered, injectable SCS systems are just as effective as commercial products at relieving pain and at creating paresthesia coverage for patients who suffer from chronic back and limb pain and have the added advantages of shortened procedure time and elimination of open ports during the trial periods, as well as elimination of the need for tunneling and pocket creation for implantable </span>pulse generators.</p></div>","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 2","pages":"Pages 102-105"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.02.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sean M. Tutton MD , Francis R. Facchini MD , Larry E. Miller PhD
{"title":"Minimally invasive treatments for osteoporotic vertebral compression fracture: Current concepts and state-of-the-art technologies","authors":"Sean M. Tutton MD , Francis R. Facchini MD , Larry E. Miller PhD","doi":"10.1053/j.trap.2013.02.008","DOIUrl":"10.1053/j.trap.2013.02.008","url":null,"abstract":"Osteoporotic vertebral compression fractures (VCFs) are common in the elderly and can result in debilitating pain, loss of function, kyphosis with resulting height loss, and reductions in quality of life. Conservative treatment of VCFs is considered the gold standard but has limited effectiveness after the initial 23-week period when the majority of uncomplicated VCFs resolve. Surgical intervention is invasive and associated with morbidity, particularly in the elderly patient with poor bone quality. Percutaneous techniques such as vertebroplasty and vertebral augmentation have revolutionized the treatment of VCFs by filling the treatment gap between conservative care and surgery. A robust series of randomized controlled trials and case series have demonstrated effective pain reduction, function improvement, and acceptable safety with these procedures. However, limitations still exist with these techniques including the need for bipedicular access, inadequate vertebral height restoration, trabecular destruction with balloon-based techniques, inability to precisely control cement delivery, and significant radiation exposure to patients and physicians. New technologies are emerging that retain the clinical advantages of traditional percutaneous vertebroplasty and vertebral augmentation while minimizing these limitations. This review article discusses the history of minimally invasive VCF treatment, summarizes clinical evidence with these therapies, and highlights the most innovative experimental and commercial technologies available today.","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 2","pages":"Pages 118-123"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.02.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in biological techniques for treatment of lumbar discogenic pain","authors":"Jeffrey D. Petersohn MD","doi":"10.1053/j.trap.2013.02.003","DOIUrl":"10.1053/j.trap.2013.02.003","url":null,"abstract":"Treatment of lumbar discogenic pain is based upon restoration of mechanical function and suppression of nociception within the intervertebral disc. The biophysical and pathologic basis of disc injury is reviewed with discussion of treatment modalities. Ablative intradiscal ethanol and restorative intradiscal fibrin appear promising. Intradiscal platelet-rich plasma is tantalizing, but unproven. Biochemical modification of anabolic-catabolic balance by intradiscal administration of growth factors including BMP-7 and GDF-5 in clinical trials, as well as multiple investigational pharmacologic moieties, is discussed. Successful use of intradiscal autologous and mesenchymal stem cells has been demonstrated for in animal models, but human experience is limited. Clinical considerations and risks of these treatments are discussed.","PeriodicalId":93817,"journal":{"name":"Techniques in regional anesthesia & pain management","volume":"16 2","pages":"Pages 89-94"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.trap.2013.02.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58056141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}