International journal of translational medical research and public health最新文献

{"title":"Cancer Registry in Bangladesh: Challenges and Opportunities","authors":"Md. Matiur Rahman, Md. Kaoser Bin Siddique, Mohammad Mahbub ur Rahim","doi":"10.25259/ijtmrph_522","DOIUrl":"https://doi.org/10.25259/ijtmrph_522","url":null,"abstract":"The Cancer Registry is a database created for collecting, managing, and storing information about people with cancer. Collaborative research, preventive, and treatment initiatives benefit nations with cancer registries. Several Asian countries have recently made their cancer registries. It is done by a designated Organization, such as the National Cancer Registry Programme (NCRP) in India and National Cancer Registry (CNCR) in China. Both countries decentralized their programs in different parts of their country. Bangladesh’s National Cancer Registry has not yet been established due to a lack of government policy, fund allocation, trained manpower, workforce, awareness, and readiness among health professionals.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140232315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Risk Assessment of Hepatitis B Infection among Barbers and Beauty Salon Workers in Mwanza, Tanzania","authors":"Semvua Kilonzo, Hyasinta Jaka, Sylvanus Mapunda","doi":"10.25259/ijtmrph_476","DOIUrl":"https://doi.org/10.25259/ijtmrph_476","url":null,"abstract":"\u0000\u0000Community-acquired hepatitis B virus (HBV) infection is increasing in developing countries. In Tanzania, there is an exponential increase in barbershops and beauty salons, which are potential sites of transmission of HBV. Occupational exposure rates and HBV vaccination rates among salon workers are unknown; their level of knowledge about infection prevention and control (IPC) is also unknown. This study aimed to evaluate the risk of infection and the knowledge of barbers and beauty salon workers about HBV transmission and prevention.\u0000\u0000\u0000\u0000A cross-sectional study was conducted using a convenience sample of 200 barbers and beauty salon workers from 13 barber shops and 13 beauty salons in the urban district of Mwanza, Tanzania. Data were collected using a self-administered questionnaire, entered into EpiData version 3.1, and analyzed with Stata version 13. Categorical variables were expressed as frequencies, and association levels were compared using Fisher’s exact test.\u0000\u0000\u0000\u0000Fifty-four percent of the study participants were female, and the mean age was 25 (21.0–29.5) years. A total of 126 (63%) participants were aware of the existence of HBV infection, of which only 22% had general good knowledge of HBV transmission and prevention. Both HBV awareness (P < 0.001) and good knowledge of its transmission and prevention (P = 0.03) were positively associated with higher levels of education. Seventy-three (36.5%) participants reported a history of occupational injuries. Merely 27.8% of participants were familiar with the correct methods of decontamination beauty tools, and only 14.3% understood the correct procedures for post-exposure wound care. Vaccination coverage was low with only (2%) of barbers and beauty salon workers having received vaccines.\u0000\u0000\u0000\u0000The frequent occupational injuries and inadequate vaccination among barbers and beauty salon workers amplify their risk of HBV infection. They also lack basic knowledge about HBV transmission and prevention, placing the clients they serve at high risk for infection. We recommend that training on HBV Infection Prevention and Control (IPC) should focus on this specific group, and the implementation of these measures should be closely monitored in barbershops and beauty salons. Moreover, this vulnerable group should be considered for a global vaccination program.\u0000","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140234566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Innovative Approach to E-mentorship for Black Applicants to Graduate Medical Education (GME) Programs","authors":"Omar M. Young, Jackyln C. Fuller, Henry W. Lewis III","doi":"10.25259/ijtmrph_3_2023","DOIUrl":"https://doi.org/10.25259/ijtmrph_3_2023","url":null,"abstract":"The path to medical education is complex and challenging. This is particularly true for Black applicants seeking to pursue graduate medical education. These individuals encounter a multitude of challenges due to disparities in access and resources. These hurdles include difficulties in navigating the residency application process and lower matriculation rates. To address these issues, medical schools need to support diverse and innovative mentorship initiatives, including E-mentoring that is specifically tailored to Black applicants. This article examines the benefits of E-mentoring from the perspectives of our innovative E-mentorship platforms.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":"307 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"State and Metropolitan Area Disparities in Long COVID-19 and Related Symptoms among US Adults, June-October 2022","authors":"Gopal K. Singh, Hyunjung Lee, Lyoung Hee Kim, R. Azuine","doi":"10.21106/ijtmrph.443","DOIUrl":"https://doi.org/10.21106/ijtmrph.443","url":null,"abstract":"Background: Little research exists on sociodemographic and geographic inequalities in Long COVID, defined as COVID-19 symptoms lasting 3 months or longer. Using the latest nationally representative data, we examine geographic disparities in prevalence of Long COVID and severe COVID symptoms among United States (US) adults aged ≥18 years. Methods: We analyzed five consecutive rounds of the US Census Bureau’s Household Pulse Survey from June 1 to October 17, 2022 (N=108,064). Using multivariable logistic regression and health disparity indices, we modeled disparities in Long COVID and severe COVID symptoms by state and metropolitan area, controlling for race/ethnicity, socioeconomic status, health insurance, and other demographic characteristics. Results: During June–October 2022, an estimated 35.4 million or 32.2% of COVID patients in the US reported developing Long COVID; and 15.2 million or 13.8% of COVID patients reported experiencing severe COVID symptoms. The prevalence of Long COVID ranged from 24.0% in the District of Columbia (DC), 25.4% in Hawaii to 39.2% in Alabama, 39.9% in Wyoming, and 43.6% in West Virginia. Adjusted for covariates, adults with COVID-19 diagnosis in Alabama, Wyoming, and West Virginia had 48-178% higher adjusted odds of developing Long COVID than their counterparts in DC. Adults with COVID-19 diagnosis in Alabama, Arkansas, Colorado, Iowa, Kentucky, Mississippi, Montana, North Dakota, South Dakota,Texas, Utah, Virginia, Wyoming, and West Virginia had 2.0-2.5 times higher adjusted odds of experiencing severe COVID symptoms than their counterparts in Vermont. Large disparities in prevalence of Long COVID and severe COVID symptoms existed among the 15 largest metropolitan areas of the US, with the prevalence of Long COVID ranging from 21.9% in San Francisco to 38.0% in Riverside, California. Socioeconomic, demographic and health insurance characteristics explained 34% of the state-level disparity and 45% of the metropolitan-area disparity in Long COVID prevalence. Conclusion and Implications for Translation: Marked geographic disparities existed, with COVID patients/survivors in the Southeast, Southwest, and Northern Plains states being at substantially higher risks of developing Long COVID and severe COVID symptoms. Equitable access to care and support services among patients with Long COVID is critical to reducing inequities in COVID-related healthoutcomes.   Copyright © 2023 Singh et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":"24 2-3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139269882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in Prevalence of COVID-19, Long COVID, Disease Severity, and Mental Health Outcomes among US Adults by Industrial Sector of Employment, September-November 2022","authors":"Gopal K. Singh, Lyoung Hee Kim, Hyunjung Lee, R. Azuine","doi":"10.21106/ijtmrph.436","DOIUrl":"https://doi.org/10.21106/ijtmrph.436","url":null,"abstract":"Background: The coronavirus disease (COVID-19) pandemic has had a major adverse impact on people’s health and well-being in the United States (US) and globally. Although inequalities in COVID-19 prevalence and to a lesser extent in Long COVID and related mental health impact among US adults have been documented, disparities in COVID-related outcomes by industrial sector of employment, an important social determinant, have not been studied. Using the latest nationally representative data, we examine disparities in COVID-19, Long COVID, and associated mental health impact among US adults aged ≥18 years by industrial sector. Methods: Using three consecutive rounds of the US Census Bureau’s Household Pulse Survey from September 14 to November 14, 2022 (N=148,813), disparities in COVID-related outcomes by industrial sector were modeled by multivariable logistic regression after controlling for race/ethnicity, socioeconomic status, health insurance, and other demographic characteristics. Results: During September–November 2022, an estimated 117 million or 48.7% of US adults reported having been diagnosed with COVID-19; 34.3 million or 29.4% of COVID patients reported developing Long COVID; 14.7 million or 12.6% of COVID patients reported experiencing severe COVID symptoms; 10.7% of COVID patients reported serious depression, and 17.8% reported serious anxiety. Adjusted for covariates, workers in wholesale trade, finance and insurance, educational services, healthcare, social assistance, and accommodation and food services had 30-39% higher odds of being diagnosed with COVID-19 than workers in the agricultural sector. Workers in social assistance, real estate, utilities, construction, and healthcare sectors had 48-102% higher adjusted odds of developing Long COVID than workers in wholesale trade. Conclusion and Implications for Translation: Marked disparities in COVID-related outcomes existed, with workers in employment industries such as healthcare, social assistance, real estate, arts and entertainment, and accommodation and food services being at increased risk of COVID-19 diagnosis, Long COVID, severe COVID symptoms, serious depression, and anxiety. Equitable access to social services and healthcare, including mental and behavioral health services, among workers afflicted with these conditions is critical to reducing inequities in COVID-related health outcomes.   Copyright © 2023 Singh et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":"12 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139270677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Reproductive and Maternal Healthcare Uptake in India: An Evaluation of Project Ujjwal Public-Private Partnership Program","authors":"Anagha Lokhande","doi":"10.21106/ijtmrph.429","DOIUrl":"https://doi.org/10.21106/ijtmrph.429","url":null,"abstract":"Background and Objective: Project Ujjwall was a public private partnership established to improve maternal and child health (MCH) outcomes in Bihar and Odisha in India. This paper examines whether Project Ujjwal meaningfully increased the usage of family planning methods and maternal health services to determine whether the Ujjwall program model should be expanded in India. This is the first attempt to establish the causal impact of Project Ujjwal on access to reproductive healthcare in India.\u0000Methods: Data were obtained from the National Family Health Survey of India. A difference-in-differences strategy and linear probability models were used to estimate the likelihood of ever having encountered family planning information or ever having used contraceptives, antenatal care, etc.\u0000Results: The sample size for Odisha was 4,540; the sample size for Bihar was 3,818; the total sample size for all states in the control group was 24,922. Within Odisha and Bihar, Project Ujjwal increased the likelihood of ever having used any contraceptive by 8.9%, increased the likelihood of having ever accessed antenatal care from a licensed doctor or nurse by 2.5% and increased the likelihood of having ever encountered family planning media by 5.1%. However, most results seem differentially driven by the success of the program in either Odisha or Bihar: among all results, only the odds that a woman received delivery assistance (2.8%) and the odds that a woman will have used oral contraceptives by (9.3%) increased statistically significant in both states.\u0000Conclusion and Implications for Translation: These results are promising and show Project Ujjwal may have been more effective than existing government programs. Limitations of this analysis include a lack of information about the demand generation tactics and an inability to include state-level fixed effects due to over-specification concerns. Disparities in the impact of Project Ujjwal on Bihar and Odisha and the lack of specific information about latent demand both suggest the need for further investigation.\u0000 \u0000Copyright © 2023 Lokhande. Published by Global Health and Education Projects, Inc.This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47555291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Students' Perceptions of Clinical and Research Training: An International Needs Assessment of 26 Countries.","authors":"Sergio M Navarro,&nbsp;Kelsey Stewart,&nbsp;Katelyn M Tessier,&nbsp;Aemon Berhane,&nbsp;Susana Prestinary Alvarado,&nbsp;Tavonga Tafirei,&nbsp;Hodan Abdi,&nbsp;Evan J Keil,&nbsp;Todd Tuttle,&nbsp;Jennifer Rickard","doi":"10.21106/ijtmrph.454","DOIUrl":"https://doi.org/10.21106/ijtmrph.454","url":null,"abstract":"<p><strong>Objective: </strong>Despite calls to incorporate research training into medical school curriculum, minimal research has been conducted to elucidate trends in research knowledge, opportunities, and involvement globally. This study aims to: (1) assess medical students' perceptions of the level of training they received on research based on their medical school training, and (2) evaluate the obstacles related to conducting research as part of medical students' training.</p><p><strong>Methods: </strong>A 94-question, bilingual survey designed by a small focus group of individuals from medical schools across the globe and administered to medical students from different parts of the world, distributed via social media networks (Twitter, Now X, Facebook) and email distributions via international partnerships from November 1 to December 31, 2020. The survey collected demographic information including age, gender, medical institution and country, degree, year in training, clinical rotations completed, plans for specialization, and additional graduate degrees completed. Statistical analysis included a summary of survey participant characteristics, and a comparison between regions, with a variety of comparison and logistic regression models used.</p><p><strong>Results: </strong>A total of 318 medical students from 26 countries successfully completed the survey. Respondents were majority female (60.1%), from Latin America (LA) (53.1%), North America (NA) (28.6%), and Other world regions (Other) (18.2%). Students felt research was an important component of medical training (87.7%), although many reported lacking research support from their institution (47.5%). There were several reported barriers to research, including lack of research opportunities (69.4%), lack of mentors (56.6%), lack of formal training (54.6%), and barriers due to the coronavirus disease 2019 (COVID-19) pandemic (49.3%). Less frequent were barriers related to financial resources (41.6%), physical resources (computer or internet access) (18%), and English language ability (6.9%). Students from Latin America and Other were more likely to report a desire to pursue research later in their medical careers compared with students from North America.</p><p><strong>Conclusions and implications for translation: </strong>Despite significant interest in research, medical students globally report a lack of formal research training, opportunities, and several barriers to conducting research, including the COVID-19 pandemic. The study highlights the need for student research training internationally and the role of further regional-specific and institutional-specific evaluation of research training needs.</p>","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexually Transmitted Infections in Pre-Exposure Prophylaxis Patients","authors":"Nicholas Sleeman, Carol Hoban, S. Koutoubi","doi":"10.21106/ijtmrph.461","DOIUrl":"https://doi.org/10.21106/ijtmrph.461","url":null,"abstract":"Background and Objective: Pre-exposure prophylaxis (PrEP) effectively prevents the spread of the human immunodeficiency virus (HIV). HIV is a disease primarily contracted by men who have sex with men or the sharing of needles, syringes, and other drug injection equipment. However, there is some disparity over the thought that PrEP patients have a disproportionate incidence of sexually transmitted infections (STIs) compared with non-PrEP patients. This study aims to clarify the disparity and identify if PrEP patients have a higher incidence of STIs.\u0000Methods: A survey of 143 respondents was conducted on STI incidence, risk factors, and abstinence from May 13, 2022, to June 20, 2022. The results were analyzed in Statistical Package for the Social Sciences (SPSS V28.0.0.0). SPSS was used to analyze the descriptive statistics associated with STI data obtained from the Naval Medical Readiness and Training Command, Camp Lejeune, Community Health Clinic Patient and Laboratory Tracker.\u0000Results: This study found a higher incidence of STIs among PrEP patients than non-PrEP patients and a statistical significance (p = 0.010) between the number of partners a person had sex with over the past year and the lifetime incidence of STIs. Portions of the data in the linear regression were used to calculate the significance and can be used as a predictor of STIs based on the number of partners a person has. This can help patients within this community understand their actual risk of contracting an STI based on a potential risk factor.\u0000Conclusion and Implications for Translation: This study found a higher incidence of STIs among PrEP patients than non-PrEP patients. Additionally, the study can help public health professionals understand the risks associated with military patients who take PrEP and target specific risk factors that influence the disparity in the incidence of STIs. Future studies may use survey data from this study to understand the implications of other risk factors and their association with STIs. Public health professionals can also use these data to develop a predictive index for many risk factors. A predictive index on STI risk is an extremely valuable tool as it allows users to view their risk of obtaining an STI.\u0000 \u0000Copyright © 2023 Sleeman and Hoban. Published by Global Health and Education Projects, Inc.This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45054196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Perceived Susceptibility, Perceived Severity, Perceived Barriers and Benefits in COVID-19 Vaccine Hesitancy and Uptake Among Outpatient Surgery Nurses in the United States: A Qualitative Study","authors":"Dania Matta, P. Herring, W. Beeson, S. Wiafe","doi":"10.21106/ijtmrph.439","DOIUrl":"https://doi.org/10.21106/ijtmrph.439","url":null,"abstract":"Background and Objective: This qualitative study explores outpatient nurses’ perceptions of coronavirus disease 2019 (COVID-19) and the COVID-19 vaccine, aiming to inform future research and health education strategies for reducing vaccination hesitancy among healthcare workers, particularly nurses. The nurses recruited for this study were all registered nurses (RNs). Studies have shown that registered professional nurses consistently display higher vaccination hesitancy versus other healthcare groups, specifically doctors. Little is known about the vaccine acceptance disparities that exist among healthcare workers, or why nurses appear to consistently display higher rates of vaccine hesitancy, versus other healthcare groups, especially doctors.\u0000Methods: Semi-structured interviews guided by the health belief model were conducted with 8 outpatient nurses, and a focus group guided by the health belief model was conducted with 5 outpatient nurses, for a total of 13 nurses (N=13). The data were triangulated through interviews, a focus group, and a literature review. In addition, an independent external secondary analyst confirmed the findings.\u0000Results: Three key themes appeared: (1) sources of information (trusted sources of information), (2) experience (belief about personal risk and personal responsibility), and (3) logistics (COVID-19 testing requirements, booster frequency, and mandate versus choice).\u0000Conclusion and Implications for Translation: We advise public health professionals to adopt a grassroots approach to vaccine hesitancy interventions, engaging and training doctors and nurses. We also recommend consistency in prevention approaches, as that produces trust. We also recommend further research into the booster requirement, as requiring an unknown number of boosters appears to lower trust among nurses.\u0000 \u0000Copyright © 2023 Matta et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46318111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of Hyperbaric Oxygenation Treatment and Evaluation of Associated Clinical Parameters: A Single-Institutional Prospective Cohort Study","authors":"Gonzalo Monge, Matías Otto-Yáñez, Nicole Norambuena, V. Martinez, Daniela Retamales, R. Torres-Castro","doi":"10.21106/ijtmrph.430","DOIUrl":"https://doi.org/10.21106/ijtmrph.430","url":null,"abstract":"Background and Objective: Adverse events (AEs) associated with hyperbaric oxygen therapy (HBOT) are uncommon and typically not serious, being the most frequent otic/sinus barotrauma. The objective of this study is to analyze the safety of the HBOT at 1.45 atmosphere absolute (ATA) and compare it with reportsat the same and higher pressures of treatment.\u0000AE per session was 7.1% for total AE and 4.1% for overall barotrauma. AE was reported in 28.3% of patients (n=49), with barotrauma and non-barotrauma AE in 20.3% (n=35) and 8.1% (n=14). All barotrauma was recorded as subjective (100% of ear ache without eardrum damage, Teed scale=0). The frequency of total AE obtained in our study was statistically higher for 1.5, 2, and >2 ATA. Non-barotrauma AE was also higher; the frequency of total AE obtained in our study was statistically significant for 1.5, 2, and >2 ATA but objective barotrauma was not present, and it was significantly lower than previously reported (p < 0.001). A very slow rate of pressurizations (below 1 psi/min) was associated with ear pain (OR=3.32; 95 CI%, 1.32-8.35; p < 0.001). The AEs reported in this safety surveillance prospective study are minor, and no objective barotrauma was reported. HBOT at 1.45 ATA is a safe treatment, that can be performed with a portable light and a less expensive hyperbaric chamber.\u0000Methods: A total of 175 patients (68 male, 107 female) were included in this prospective study. All patients were treated with HBOT at our facility from December 2019 to August 2021. For the comparative analysis, reports from studies published from 2012 to 2021 in MEDLINE EMBASE, BIREME, Lilacs, Scielo, and the Cochrane library were used. Binary variables are described in percentages with a 95% confidence interval (95% CI). Inferential analysis was performed using a bivariate analysis by calculating odds ratio (OR) with 95% confidence intervals. Statistical analyses and sample size calculations were performed with Stata version 13.0 (College Station, TX, USA).\u0000Results: In this study, the AE per session was 7.1% for total AE and 4.1% for overall barotrauma. AE was reported in 28.3% of patients (n=49), with barotrauma and non-barotrauma AE in 20.3% (n=35) and 8.1% (n=14), respectively. All barotrauma was recorded as subjective (100% of ear ache without eardrum damage, Teed scale=0). The frequency of total AE obtained in our study was statistically higher for 1.5, 2, and >2 ATA. Non-barotrauma AE was also higher, but objective barotrauma was not present and was significantly lower than previously reported (p <0.001). A very slow rate of pressurizations (below 1psi/minute) was associated with ear pain (OR = 3.32; 95% CI, 1.32-8.35; p <0.001).\u0000Conclusion and Implications for Translation: In this study, the AE reported in this prospective safety surveillance study are minor, and no objective barotrauma was reported. The HBOT at 1.45 ATA is a safe treatment that can be performed with a portable lighter and a less expensive hyperbar","PeriodicalId":93768,"journal":{"name":"International journal of translational medical research and public health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43496242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}