Bulletin of Problems Biology and Medicine最新文献_第4页

THE ROLE OF EPITHELIAL-MESENCHYMAL TRANSFORMATION IN INFERTILITY CAUSED BY CHRONIC ENDOMETRITIS 上皮-间质转化在慢性子宫内膜炎所致不孕症中的作用

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-1-168-343-351

D. Kiriya

引用次数: 0

BIOLOGICAL EFFECTS OF THE LOW-MOLECULAR FRACTION OF THE DORSAL ROOT GANGLIA CRYOEXTRACT ON THE REPRODUCTIVE SYSTEM OF FEMALE RATS 背根神经节低温提取物低分子组分对雌性大鼠生殖系统的生物学影响

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-402-409

А. V. Nesteruk, E. Legach

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NON-SPECIFIC ADAPTIVE REACTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION (STEMI) AT DIFFERENT BODY WEIGHTS 不同体重急性冠状动脉综合征st段抬高患者的非特异性适应反应

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-269-277

N. Lutsiv, V. Akimova, O. Labinska, M. P. Halkevich, N. R. Demyanchuk, M. Shchurko, L. P. Kostiuk

{"title":"NON-SPECIFIC ADAPTIVE REACTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION (STEMI) AT DIFFERENT BODY WEIGHTS","authors":"N. Lutsiv, V. Akimova, O. Labinska, M. P. Halkevich, N. R. Demyanchuk, M. Shchurko, L. P. Kostiuk","doi":"10.29254/2077-4214-2023-2-169-269-277","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-269-277","url":null,"abstract":"three research groups (79 patients) were analyzed: Group I - 28 patients with STEMI and normal body weight, Group II - 24 patients with STEMI and excess body weight, and Group III - 27 patients with STEMI and obesity of the I-III degrees. The diagnosis (acute coronary syndrome) of ACS was made based on a complex clinical, laboratory and instrumental examination. Blood was taken for the study when patients were admitted to the department. The total number of leukocytes and the leukocyte blood formula were determined by standardized methods; the type of non-specific adaptation reaction - according to the method of L.H. Harkavi; the ratio of the absolute content of neutrophils to the absolute content of lymphocytes (neutrophil to lymphocyte ratio, NLR), and the ratio of the absolute content of neutrophils to the absolute content of platelets (neutrophil to platelet ratio, NPR) was determined. The course of ACS occurs against the background of several non-specific adaptation reactions, where the stress reaction was dominant (42.8% - group I, 50% - group II, and 51.9% - group III), indicating the disease's severity. The highest level of NLR (p<0.05) was found in group III, relative to the NLR indicator in group I and group II, and the highest level of NPR was found in group III precisely in case of a stress reaction, which indicates an unfavourable prognosis for patients of this group. Determining the type of nonspecific adaptation reaction can serve as an additional indicator of the severity of the patient and allows us to assess the effectiveness of therapy in patients with STEMI. The indicators of NLR and NPR were useful and powerful indicators of adverse consequences during the hospitalization of patients with ACS. The type of adaptive response and the indicators of NLR and NPR are determined based on clinical blood analysis indicators, and they are economical biomarkers for predicting the severity of inflammation.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88387091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE EFFECTIVENESS OF THE INFLUENCE OF A COMPLEX OF PHYSICAL EXERCISES ON THE RESULTS AND EVALUATION OF PHYSICAL WORKABILITY IN CHILDREN WITH SCOLIOSIS 综合体育锻炼对脊柱侧凸儿童身体可操作性评估结果影响的有效性

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-1-168-429-434

D. Dychko, O. Dychko, O. Nekhanevich, I. V. Kushakova, O. Zinoviev, V. Dychko, O. Shayda

引用次数: 0

CHANGES IN HEMATOLOGICAL INDICATORS IN PATIENTS WITH CORONAVIRUS DISEASE 冠状病毒病患者血液学指标的变化

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-1-168-120-130

O. Voronkova, O. Pavlova, O. Starishko, O. M. Prykhodko, A. V. Narbiekova, O. M. Simonova

引用次数: 0

DYNAMIC COMPARISON THE THIGH LENGTH IN STUDENTS OF BUKOVYNA 布科维纳学生大腿长度的动态比较

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-424-431

Karatieieva Svitlana, Yuriyivna Каратєєва, Світлана Юріївна

{"title":"DYNAMIC COMPARISON THE THIGH LENGTH IN STUDENTS OF BUKOVYNA","authors":"Karatieieva Svitlana, Yuriyivna Каратєєва, Світлана Юріївна","doi":"10.29254/2077-4214-2023-2-169-424-431","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-424-431","url":null,"abstract":"A paired t-test (paired-samples t-test) was performed to compare the respondents' indicators during the first and second measurements a year later. Statistical analysis of the obtained data was carried out using the licensed program RStudio. When testing the hypothesis that the average value of the length of the right thigh significantly increased, a significant increase in the length of the right thigh was found between the first (M=53.870, SD=4.098) and the second (M=54.319, SD=4.118) measurements; t(68)= -6.704, p<0.001. The average value of the length of the left thigh also increased significantly, and there was a significant increase in the length of the left thigh between the first (M=53.855, SD=4.237) and the second (M=54.478, SD=4.161) measurements; t(68)= -5.328, p<0.001. A comparison of the length of the thigh in the dynamics after a year; in student-athletes of the main group showed a difference in the increase of the length of the thigh in 2022 compared to 2021 (±0.48-0.62 cm). According to the comparison of the left and right thigh during the second measurement of student-athletes, no significant difference in the average length of the right and left thigh was found (right – 54.31±2.04 cm, left – 54.47±2.04 cm). A significant predictor of thigh length is height. A model was derived for predicting the length of the right thigh Lr = 0.308 h and the left Ll = 0.309 h, where L is the length of the thigh, h is height. The coefficient of determination is 99.8%.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86608844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE BIOGRAPHICAL METHOD AS A MEANS OF FORMING THE PROFESSIONAL PERSONALITY AND PROFESSIONAL IDENTITY OF THE FUTURE DOCTOR (as exemplified by the integration of the study of human anatomy and the disciplines of the foreign language training cycle) 作为形成未来医生职业人格和职业认同的手段的传记法(以人体解剖学研究与外语训练周期学科的整合为例)

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-1-168-224-232

O. Bieliaieva, S. Bilash, O. Pronina, Y. Lysanets, V. P. Bilash, K. Havrylieva, Z. Taran

引用次数: 1

USE OF HEALTH-PRESERVING FEATURES OF LEARNING IN THE CONTEXT OF OPTIMIZATION AND IMPROVEMENT OF PEDAGOGICAL MANAGEMENT IN HIGHER MEDICAL EDUCATION 在优化和改进高等医学教育教学管理的背景下利用学习的养生特色

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2022-4-167-251-254

V. P. Bilash, N. Svintsytska, S. Bilash, O. Pronina, O. Bilanov, Ya. O. Oliinichenko, O. T. Tkachenko

引用次数: 0

THE CONCEPT OF NITRO-OXIDATIVE STRESS IN ACUTE GENERALIZED PERITONITIS ON THE BACKGROUND OF OBESITY IN EXPERIMENT 肥胖背景下急性广泛性腹膜炎硝基氧化应激的概念

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2077-4214-2023-2-169-277-281

Lutsiv Natalia, Zbyslavivna, Луців Наталія, Збиславівна, I. Horbachevsky

{"title":"THE CONCEPT OF NITRO-OXIDATIVE STRESS IN ACUTE GENERALIZED PERITONITIS ON THE BACKGROUND OF OBESITY IN EXPERIMENT","authors":"Lutsiv Natalia, Zbyslavivna, Луців Наталія, Збиславівна, I. Horbachevsky","doi":"10.29254/2077-4214-2023-2-169-277-281","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-277-281","url":null,"abstract":"Obesity was simulated using a high-calorie diet. On the 1st day, the level of NOx metabolites in the blood serum of the group of animals with AGP on the background of obesity was 9 % significantly higher than that of the group of animals with isolated GPP, on the 3rd day – by 8 %, and on the 7th day – by 7 %, respectively (р<0,05). Comparing the indicators of NO-synthase activity in the liver of the rats of the main group and the comparison group, we obtained higher indicators in the animals of the AGP group and the background of obesity during all periods of the experiment: on the 1st day – by 16 %, on the 3rd day – by 14 %, and on the 7th day – by 13 % (р<0,05). The mechanisms of nitrooxidative stress are significantly increased in animals with AGP against the background of obesity during all periods of the experiment, which is confirmed by statistically significantly higher levels of NO-synthase in the liver and the content of nitrates and nitrites in blood serum compared to animals with isolated obe - sity or animals with AGP.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82492583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

МОЖЛИВОСТІ ВИКОРИСТАННЯ КРІОЕКСТРАКТУ ПЛАЦЕНТИ ДЛЯ ОПТИМІЗАЦІЇ РЕПАРАТИВНОЇ РЕГЕНЕРАЦІЇ КІСТКОВОЇ ТКАНИНИ ПІСЛЯ ОПЕРАЦІЇ ВИДАЛЕННЯ ЗУБА

Bulletin of Problems Biology and Medicine Pub Date : 2023-01-01 DOI: 10.29254/2523-4110-2023-2-169/addition-20

Давид Соломонович Аветіков, В. В. Хатту, Ігор Олексійович Іваницький, О. С. Іваницька, Ольга Петрівна Буханченко

引用次数: 0