Forensic genomics最新文献_第3页

The Idaho Student Homicides and the Future of Forensic Genetic Genealogy 爱达荷州学生凶杀案和法医基因谱系的未来

Forensic genomics Pub Date : 2023-03-02 DOI: 10.1089/forensic.2023.0004

Nicole M. M. Novroski

引用次数: 0

Developmental Validation of the Illumina Infinium Assay Using the Global Screening Array on the iScan System for Use in Forensic Laboratories 利用iScan系统上的全局筛选阵列开发验证Illumina Infinium检测，用于法医实验室

Forensic genomics Pub Date : 2023-03-01 DOI: 10.1089/forensic.2022.0013

David A. Russell, Erin M. Gorden, Michelle A. Peck, Christina M. Neal, Mary C. Heaton, Jessica L. Bouchet, Alexander F. Koeppel, Elayna Ciuzio, Stephen D. Turner, Carmen R. Reedy

{"title":"Developmental Validation of the Illumina Infinium Assay Using the Global Screening Array on the iScan System for Use in Forensic Laboratories","authors":"David A. Russell, Erin M. Gorden, Michelle A. Peck, Christina M. Neal, Mary C. Heaton, Jessica L. Bouchet, Alexander F. Koeppel, Elayna Ciuzio, Stephen D. Turner, Carmen R. Reedy","doi":"10.1089/forensic.2022.0013","DOIUrl":"https://doi.org/10.1089/forensic.2022.0013","url":null,"abstract":"Microarray processing, which interrogates hundreds of thousands of single nucleotide polymorphisms (SNPs) across the human genome, has recently gained traction in forensics due to its use in forensic genetic genealogy, which is based on analysis using SNPs to compare distant relatives in publicly curated databases for the purposes of developing investigative leads or identifying human remains. To date, there has been no published developmental validation of microarray processing using the Scientific Working Group on DNA Analysis Methods (SWGDAM) Validation Guidelines for DNA Analysis Methods and Federal Bureau of Investigation Quality Assurance Standards. Validation of these methods are warranted to identify samples suitable for microarray analysis and to assess the quality of the data obtained before upload to genealogical databases. In this study, we validated the Global Screening Array for use in forensic investigations according to SWGDAM guidelines, including the following studies: precision and accuracy, sensitivity, contamination, degradation, species specificity, mock case-type samples, mixtures, repeatability and reproducibility, and stability. Results indicated accurate genotype calls with SNP call rates >95% at DNA input as low as 0.20 ng. In addition to SNP call rate, we developed interpretation thresholds for signal intensity and heterozygosity to allow for sample quality assessment and identification of highly degraded and/or non-human DNA. This study demonstrates that high-quality data can be generated from multiple sample types, including mock forensic evidence that simulated the challenges that are often encountered in forensic cold cases.","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"174 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136095449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of Religious Inbreeding on the Genetic Structure of the Subpopulations Versus Villages from Lebanon 宗教近亲繁殖对黎巴嫩亚群与村落遗传结构的影响

Forensic genomics Pub Date : 2023-03-01 DOI: 10.1089/forensic.2023.0001

Sarah Abbas, Ijaz Anwar, I. Mansour

引用次数: 0

Acknowledgment of Reviewers 2022 审稿人致谢

Forensic genomics Pub Date : 2023-03-01 DOI: 10.1089/forensic.2022.29014.ack

{"title":"Acknowledgment of Reviewers 2022","authors":"","doi":"10.1089/forensic.2022.29014.ack","DOIUrl":"https://doi.org/10.1089/forensic.2022.29014.ack","url":null,"abstract":"Forensic GenomicsVol. 3, No. 1 AcknowledgmentFree AccessAcknowledgment of Reviewers 2022Published Online:15 Mar 2023https://doi.org/10.1089/forensic.2022.29014.ackAboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail Critical evaluations of articles by expert reviewers make a vital contribution to ensuring the high quality of a journal's content. The editorial leadership of Forensic Genomics is very grateful for the support of the highly qualified peer reviewers who have dedicated their time and effort to reviewing our articles. We would like to show our appreciation by thanking the following individuals for their assistance with the review of articles for the journal in 2022.**Data through November 30, 2022.Lisa BrightBruce BudowleBrendan ChapmanDaniela CuencaKatherine GettingsJodi IrwinHarmeet KaurAna NeckovicNicole NovroskiMuhammad SajjadNathan ScudderChristopher StaleyAndreas TillmarIrina VelskoJodie WardFrank WendtFiguresReferencesRelatedDetails Volume 3Issue 1Mar 2023 InformationCopyright 2023, Mary Ann Liebert, Inc., publishersTo cite this article:Acknowledgment of Reviewers 2022.Forensic Genomics.Mar 2023.30-30.http://doi.org/10.1089/forensic.2022.29014.ackPublished in Volume: 3 Issue 1: March 15, 2023Online Ahead of Print:January 27, 2023PDF download","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136173679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Biomedical Communication in Forensic Genetics Education: An Interview with Michie Wu 生物医学传播在法医遗传学教育中的作用:吴美琪访谈

Forensic genomics Pub Date : 2023-03-01 DOI: 10.1089/forensic.2023.0003

Nicole M. M. Novroski

引用次数: 0

Highlighting the Forensic Impact of ISHI33 突出ISHI33的法医影响

Forensic genomics Pub Date : 2022-12-16 DOI: 10.1089/forensic.2022.29015.editorial

Nicole M. M. Novroski

引用次数: 0

Correction to: Developmental Validation of the forensicGEM Universal Kit for the Extraction of Genomic DNA, by Conte et al. Forensic Genom 2022;2(3):71–79; doi: 10.1089/forensic.2022.0008 更正:用于提取基因组DNA的法医gem通用试剂盒的发展验证，由Conte等人编写。法医基因组2022;2(3):71-79;doi: 10.1089 / forensic.2022.0008

Forensic genomics Pub Date : 2022-11-11 DOI: 10.1089/forensic.2022.0008.correx

引用次数: 0

Developmental Validation of the forensicGEM Universal Kit for the Extraction of Genomic DNA 法医gem基因组DNA提取通用试剂盒的开发验证

Forensic genomics Pub Date : 2022-09-20 DOI: 10.1089/forensic.2022.0008

J. Conte, Janine Kishbaugh, Dylan J. Baxter, Robert Thompson, Shrivastava Pankaj, R. Chilukuri, Pamela Marshall

引用次数: 0

Forensic Genomics: A New Era 法医基因组学:一个新时代

Forensic genomics Pub Date : 2022-09-20 DOI: 10.1089/forensic.2022.29013.editorial

Nicole M. M. Novroski

引用次数: 0

Relationship Inference with Low-Coverage Whole Genome Sequencing on Forensic Samples 法医样本低覆盖率全基因组测序的关系推断

Forensic genomics Pub Date : 2022-09-01 DOI: 10.1089/forensic.2022.0009

V. Nagraj, M. Scholz, Shakeel Jessa, Jianye Ge, Meng Huang, August E. Woerner, Dixie Peters, B. Budowle, M. Coble, Stephen D. Turner

引用次数: 2