Journal of Translational Critical Care Medicine最新文献_第4页

Timing for Initiating Renal Replacement Therapy in Patients with Acute Kidney Injury: Late is Better? 急性肾损伤患者开始肾脏替代治疗的时机:越晚越好?

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-21-00025

K. Yu

引用次数: 0

Timing and Route of Nutritional Therapy for Severe Acute Pancreatitis: From Bench to Bedside 营养治疗重症急性胰腺炎的时机和途径:从实验室到床边

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-21-00027

Z. Chang, Siying Chen, X. Chu, C. Di

引用次数: 0

Online objective structured clinical examination in critical care teaching: A pilot study 在线客观结构化临床考试在重症监护教学中的初步研究

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-21-00029

Chu-lin Huang, Hai-jun Wang, S. Qu, Hao Zhang, Hao Wang, Xue-zhong Xing

引用次数: 0

Early Clinical Management of Sepsis: Past, Present, and Future 脓毒症的早期临床管理:过去，现在和未来

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-22-00016

C. Coopersmith, Jerome C. Anyalebechi

引用次数: 1

A Step-up Approach for the Management of Infected Pancreatic Necrosis 感染性胰腺坏死的一种升级治疗方法

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm_d-21-00022

F. Cao, Jinwei Yao, Da Liu

引用次数: 0

Less is more in Corona Virus Disease 2019 2019冠状病毒病少即是多

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-21-00019

Jingjing Xu, K. Kang, Fu Li, Dong-sheng Fei, Wei Yang, Changsong Wang, Kaijiang Yu

{"title":"Less is more in Corona Virus Disease 2019","authors":"Jingjing Xu, K. Kang, Fu Li, Dong-sheng Fei, Wei Yang, Changsong Wang, Kaijiang Yu","doi":"10.4103/jtccm-d-21-00019","DOIUrl":"https://doi.org/10.4103/jtccm-d-21-00019","url":null,"abstract":"both the World Health Organization guidance for the clinical management of COVID‐19 and the National Institutes of Health COVID‐19 treatment guidelines. However, the effect of glucocorticoid on patients with COVID‐19 is controversial. According to a study,[5] dexamethasone group VS standard care group was no significant difference in mortality, intensive care unit‐free days, or mechanical ventilation duration. Hence, glucocorticoid is not to use regularly. Finally, according to the above review, immunotherapy or targeted therapy is not recommended for now. We need more clinical trials for immunotherapy in COVID‐19 to guide us to personalized use. Contrary, what we think needs to be done: Proper nutritional support is another important therapy for COVID‐19, enteral nutrition, the earlier the better; then, anticoagulant therapy is necessary to prevent thrombosis. There are lots of studies that reported that thromboprophylaxis was associated with a lower risk of death and a lower cumulative incidence of thromboembolic events, especially with high doses.[6] In addition, the fever, cough, and other symptoms of the patient should be treated by symptomatic treatment. For oxygen, perform in the prone position and tidal volume for ventilation (<10 ml/kg). Last but not least, organ support such as a ventilator, continuous renal replacement therapy, and extracorporeal membrane oxygenation are in clinical trials,[1] the results are being expected.","PeriodicalId":93326,"journal":{"name":"Journal of Translational Critical Care Medicine","volume":"9 1","pages":"1 - 2"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89391859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Update of Thoracic Epidural Analgesia Used in Acute Pancreatitis 胸廓硬膜外镇痛在急性胰腺炎中的应用进展

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-21-00021

Xiaoyun Fu, Bao Fu, Zhengguang Geng

引用次数: 0

Pain and its management in severe acute pancreatitis 重症急性胰腺炎的疼痛及其处理

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/2665-9190.343745

Zhengying Jiang, Y. Long, Guixin Wu

引用次数: 1

Corticosteroids Utilization in the Management of Critically Ill Coronavirus Disease-2019 Pneumonia 糖皮质激素在重症冠状病毒病-2019肺炎治疗中的应用

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm.JTCCM-D-21-00011

Cheng Yang, Jiahao Zhang, Rongzhang Dou, Zhongyi Sun, Jie Yang, Li He, Nanhui Jiang, Rong Huang, Feng Yuan, G. Xiao, Quan Gan, Q. Lu, Z. Peng, L. Su

{"title":"Corticosteroids Utilization in the Management of Critically Ill Coronavirus Disease-2019 Pneumonia","authors":"Cheng Yang, Jiahao Zhang, Rongzhang Dou, Zhongyi Sun, Jie Yang, Li He, Nanhui Jiang, Rong Huang, Feng Yuan, G. Xiao, Quan Gan, Q. Lu, Z. Peng, L. Su","doi":"10.4103/jtccm.JTCCM-D-21-00011","DOIUrl":"https://doi.org/10.4103/jtccm.JTCCM-D-21-00011","url":null,"abstract":"Background: There are controversies regarding corticosteroids using in coronavirus disease-2019 (COVID-19) pneumonia in the current pandemic. Objectives: This study investigates the efficacy and safety profiles of corticosteroids therapy in COVID-19 patients. Methods: Retrospective, multicenter study case series of consecutive patients with confirmed COVID-19 infection at the whole hospital from January 1 to March 1, 2020, were enrolled. Demographic, clinical, radiological, laboratory, and treatment data were collected and analyzed. The effect of corticosteroids therapy on death and organ-failure complications of pneumonia were analyzed by logistic regression. Results: A total of 470 COVID-19 patients at the whole hospital were enrolled. According to the time of corticosteroids initiation and severity of illness, there were 159 patients stratified into critical ill group and 64% (102 of 159) patients received corticosteroids treatments. Ninety-four percent (166 of 176) of corticosteroids were methylprednisolone. The median cumulative corticosteroids dosage was 300 mg equivalent of methylprednisolone over a median duration of 6 days. Multivariate regression analysis showed that corticosteroids use did not affect the mortality. However, corticosteroids therapy at moderate cumulative doses (total exposure 480 mg to 1200 mg) was associated with deceased occurrence of organ-failure complications in critically ill COVID-19. Conclusions: Corticosteroids have no effect to mortality in COVID-19 patients. The moderate cumulative doses of corticosteroids might decrease organ-failure complications in critically ill COVID-19. Further large-scale randomized controlled trials are warranted to confirm our findings, until then use of corticosteroids should be used with caution COVID-19 patients.","PeriodicalId":93326,"journal":{"name":"Journal of Translational Critical Care Medicine","volume":"39 1","pages":"1 - 7"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78968322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endotoxemic Sepsis: Clinical Features and Therapy 内毒素脓毒症:临床特征和治疗

Journal of Translational Critical Care Medicine Pub Date : 2022-01-01 DOI: 10.4103/jtccm-d-22-00015

J. Kellum, H. Shoji, D. Foster, P. Walker

引用次数: 2